115 results about "Palmitates" patented technology

The present invention relates to a precise lactation feed for lactating sows, and 100 kg of the feed product comprises the following raw materials by weight: 20 to 28 kg of soybean meal, 2 to 5 kg of fish meal, 2 to 5 kg of MCT microcapsules, 0.2 to 0.4 kg of rumen protected methionine, 0.1 to 0.2 kg of rumen protected tryptophan, 1.5 to 2.5 kg of inulin, 1 to 2 kg of sodium lignin sulfonate, 0.01 to 0.03 kg of a fenugreek seed extract, 1.2 to 1.8 kg of sn-2 palmitate, 0.4 to 0.6 kg of alpha-ketoglutaric acid, 0.08 to 0.12 kg of glycine iron, and the balance of water. The feed is prepared from the following raw materials by weight: 0.15-0.25 kg of zinc methionine, 4-8 kg of wheat bran, 1.2-1.8 kg of a calcium propionate solution, 2-3 kg of lactic acid bacteria fermentation liquor, 0.2-0.4 kg of a rosemary extract and the balance of corn, wherein the total weight of the raw materials is 100 kg. The feed is a precise nutrition regulation feed formula for the sows in the lactation period, and milk yield increase, piglet weaning performance optimization and sow body condition protection are achieved through multi-dimensional nutrition intervention.

The invention relates to the field of cosmetics, and particularly discloses a novel magical color magnetic plane water-gloss cream and a preparation method thereof.The novel magical color magnetic plane water-gloss cream is prepared from, by weight, 20%-60% of hydrogenated polyisobutene, 10%-55% of isononyl isononanoate, 1%-15% of styrene / isoprene copolymer, 0.1%-8% of dextrin palmitate, 0.2%-16% of film-forming agent, 0.01%-0.5% of antioxidant, 0.1%-1% of preservative and 0.01%-10% of magnetic pearling agent. And 0.35-13% of a humectant. A wax-free formula is adopted, a transparent raw material is used as a basis, a magnetic pearling agent with magnetic attraction force is matched, filling can be carried out through a mold with a magnet, magnetic pearling agent particles are induced to be directionally arranged, formed patterns can be not limited according to mold modeling, a common filling machine is adopted as filling equipment, and products with uniform formula, color and pattern lines can be obtained. And the formula paste is transparent and stable, and has good skin feeling and makeup effect.

The present invention relates to the field of pharmaceuticals and health food technology, and specifically to a method for preparing and applying red date polysaccharides. The specific technical solution comprises the following steps: a method for preparing red date polysaccharides comprises concentrating jujubes with distilled water, removing proteins, and then precipitating with ethanol to obtain a primary ethanol precipitate containing polysaccharides; dialyzing the primary ethanol precipitate, and then precipitating with ethanol to obtain a secondary ethanol precipitate containing polysaccharides, which is then freeze-dried. The extracted red date polysaccharides can improve glucose utilization, increase GLUT4 protein expression, and prevent palmitate-induced insulin resistance and muscle damage in muscle cells, and can be used to prevent, improve, or treat anabolic or muscular diseases.

The invention belongs to the technical field of compositions, and provides a moisture-retaining and eye-moistening composition as well as a preparation method and application thereof. According to the moisturizing eye-moistening composition provided by the invention, the soybean lecithin, the retinol palmitate lipidosome, the xanthophyll, the oligomeric hyaluronic acid and the ethylenediamine tetraacetic acid in a specific ratio are combined, and all the components can play a good synergistic effect, so that the effects of relieving asthenopia symptoms, protecting eyesight and maintaining normal vision are improved; the eye drops can improve and relieve eye dryness and eye astringency symptoms caused by various reasons (such as fatigue, wearing of contact lenses, use of electronic products, excessive use of eyes and the like).

The invention relates to the technical field of titanium dioxide production, in particular to high-retention and high-weather-resistance titanium dioxide as well as a preparation method and application thereof. Comprising a titanium dioxide base material and a coating layer located on the surface of the titanium dioxide base material, and the coating layer sequentially comprises an aluminum oxide film layer, a tin oxide film layer and an ascorbyl palmitate film layer from inside to outside. The preparation method comprises the following steps: preparing titanium dioxide-based material slurry, sequentially carrying out aluminum oxide coating and tin oxide coating, then carrying out water washing, flash evaporation and steam powdering, and adding ascorbyl palmitate in the steam powdering process to obtain the high-retention and high-weather-resistance titanium dioxide. The tin coating layer and the ascorbyl palmitate coating layer are introduced to the outer side of the aluminum oxide coating layer, so that the retention rate and weather resistance of titanium dioxide in paper are remarkably improved, and the use requirements of high-end paper are met; the white water treatment pressure can be reduced, and the economic benefit is improved.

The invention discloses a reagent combination for protecting fragment integrity in DNA methylation detection, the reagent combination is used for protecting fragment integrity in DNA methylation detection sample transformation, and the reagent combination comprises tetrahydrofurfuryl alcohol, L-ascorbyl palmitate and ethylenediamine tetraacetic acid; wherein the volume concentration of the tetrahydrofurfuryl alcohol is 10%-80%; the molar concentration of the L-ascorbyl palmitate is 10 mM to 100 mM; the molar concentration of the ethylenediamine tetraacetic acid is 1 mM to 10 mM. The invention also provides a kit and a method for DNA conversion by using the kit. According to the reagent combination, damage of sulfite to DNA in the transformation process can be reduced, DNA degradation is prevented, a transformed fragment is longer than that of a traditional transformation method, the DNA recovery concentration and the library concentration are higher, follow-up detection is facilitated, and the sensitivity of a follow-up detection method is improved.

The invention discloses application of a lycium barbarum Lb03G03224 gene in catalysis of esterification of free carotenoids, the nucleotide sequence of the lycium barbarum Lb03G03224 gene is as shown in SEQ ID NO: 1, and the amino acid sequence of encoded protein is as shown in SEQ ID NO: 2. According to the present invention, it is found that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate thereof can be generated when the Lb03G03224 gene is expressed in the engineering escherichia coli for generating beta-carotene, beta-cryptoxanthin and zeaxanthin, such that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate can be produced, the protein coded by the Lb03G03224 has the function of catalyzing esterification reaction of carotenoid containing free hydroxyl and fatty acid acyl donor, and has important application value in in-vitro biosynthesis of esterified carotenoid.

The invention relates to a composition containing anti-wrinkle lipidosome for cosmetic preparation and a preparation method of the composition, and belongs to the technical field of cosmetics. The invention discloses a composition containing anti-wrinkle lipidosome and a preparation method thereof. The composition comprises four plant extracts of purple coneflower, calendula officinalis, salvia officinalis and elderberry, and lipidosome consisting of lecithin, cholesterol, sphingomyelin and ascorbyl palmitate, and is supplemented with components such as a humectant and an emulsifier. According to the composition, through the synergistic effect of the plant extract and the lipidosome, the anti-wrinkle effect is enhanced, and the storage and illumination stability is improved; an extract structure is optimized by a compound fermentation process, and a liposome system is adapted; the components are safe and suitable for multiple skin types, the preparation process is compatible with industrial production, and the pain points that traditional anti-wrinkle products are poor in stability and insufficient in effect are solved.

The research finds that the SUMOylation level of the liver in a clinical specimen and an animal model of the metabolic dysfunction fatty liver disease is obviously reduced. UBC9 is used as the only key E2 ligase for SUMOylation to regulate and control the SUMOylation level. The invention discloses application of a UBC9 gene overexpression preparation in drugs for treating or preventing metabolic dysfunction fatty liver diseases. Through overexpression of liver specificity UBC9 mediated by an AAV adeno-associated virus vector or overexpression of UBC9 in HepG2 cells by a lentiviral vector, lipid deposition of a C57 mouse liver induced by high fat diet and a cell model treated by palmitate can be remarkably improved, and reduction of the SUMOylation level of the mouse liver and the human HepG2 cells under the high fat background can be reversed. Therefore, the UBC9 gene overexpression preparation can be used for developing drugs for treating metabolic dysfunction fatty liver diseases.

The invention belongs to the technical field of resveratrol synthesis, and particularly relates to a preparation method of resveratrol and application of resveratrol in meat preservation. The method comprises the following steps: taking 3, 5-dimethoxybenzoic acid as a raw material, and carrying out acylation reaction to obtain 3, 5-dimethoxybenzoyl chloride. Then reacting with p-acetoxystyrene to generate 3, 3 '-dihydroxy-3, 3'-dihydroxy-3 The preparation method comprises the following steps: taking 1, 5-dimethoxy-4 '-acetoxystilbene as a raw material, hydrolyzing and demethylating to obtain resveratrol, and preparing resveratrol lipid nanoparticle suspension by taking resveratrol, a ZIF-8 / chitosan compound, compound lipid, cholesterol, epsilon-polylysine, ascorbyl palmitate and phosphate buffer saline as raw materials. High load and controlled release of resveratrol are achieved, and the problems that resveratrol is poor in water solubility and prone to oxidation are solved.

The invention relates to a livestock breeding technology, and discloses a preparation method of a premix for enhancing laying hen production treatment, in the construction of a basic nutrition framework, the construction of a vitamin system is a core project, vitamin A is supplemented by adopting a palmitate form, the stability of the vitamin A in feed processing is ensured, the level of 8000-12000IU should be maintained in each kilogram of feed, and the content of the vitamin A in the feed processing is reduced. According to the fallopian tube mucous membrane composition, the addition amount of the vitamin D3 in the metabolic activity form of 25-hydroxyD3 needs to reach 2000-3000 IU / kg, the vitamin D3 and parathyroid hormone have a synergistic effect, the calcium and phosphorus deposition efficiency can be remarkably improved, particularly, the synergistic effect of B vitamins is worthy of attention, and thiamine (B1) and riboflavin (B2) are compatible according to the proportion of 1: 2. According to the preparation method of the premix for enhancing laying hen production treatment, the growth speed and the laying efficiency of chicken flocks are effectively improved, the eggshell quality is ensured, nutritional diseases such as chondropathy and egg reduction diseases are reduced, and the economic benefits of laying hen breeding are greatly improved.

This rotigotine-containing adhesive patch comprises a support layer and an adhesive layer, wherein the adhesive layer contains: at least one selected from the group consisting of rotigotine and pharmaceutically acceptable salts of rotigotine; a rubber-based adhesive base; and an antioxidant. The antioxidant includes propyl gallate, ascorbyl palmitate, and sodium pyrosulfite.

This invention discloses a soothing and repairing composition and its application, comprising the following raw materials: phytosterols, chamomile extract, hydrolyzed sodium hyaluronate, tocopherol, ceramide NP, triethanolamine, lactobacillus, macadamia seed oil, magnolia alcohol, matricaria flower extract, maltodextrin, lecithin, phosphatidylcholine, ascorbyl palmitate, inulin root juice, arginine / lysine polypeptide, squalane, jojoba seed oil, scutellaria baicalensis root extract, polygonum cuspidatum root extract, fructose, glycerin, p-hydroxyacetophenone, butylene glycol, acrylate / C10-30 alkanol acrylate crosspolymer, α-glucan oligosaccharide, 1,2-hexanediol, and water as the balance. Compared with the prior art, the soothing and repairing composition prepared by this invention has the effects of rapidly rebuilding the skin barrier, regulating skin immune function, improving skin microecology, synergistic effect, and rapid skin repair.

The present invention provides pharmaceutical compositions comprising a therapeutically effective dose of vitamin A palmitate; processes for their preparation, and uses and methods of treatment comprising them. The compositions provided by the present invention may be used in the treatment and / or prophylaxis of conditions and diseases caused by vitamin A deficiency.

The invention provides starch sodium octenylsuccinate-free, protein-free and lactose-free fat powder as well as a preparation method and application thereof, and belongs to the technical field of foods. The fat powder provided by the invention comprises 25%-60% of glucose syrup (in terms of solid matter), 1%-20% of maltodextrin, 20%-50% of edible plant blend oil, 0.01%-3% of mono-and diglycerol fatty acid ester, 0.01%-3% of citric acid fatty glyceride, 0.1%-1% of sodium ascorbate, 0.005%-0.02% of ascorbyl palmitate and 0.01%-1% of potassium hydroxide. The fat powder provided by the invention is free of starch sodium octenylsuccinate, protein and lactose, good in solubility, good in dispersity and high in sinking speed. After being dissolved, the emulsion is milky white, has no (or few) small oil droplet floating, no precipitate and no floating object, and after standing, the solution is not layered.

The present application relates to the field of feed additive, and discloses a feed additive, a preparation method and application thereof.The feed additive contains astaxanthin, curcumin, vitamin C palmitate, vitamin E, vitamin D3, piperine and a carrier.The preparation method comprises the following steps: mixing astaxanthin, curcumin, vitamin C palmitate, vitamin E, vitamin D3, piperine and the carrier.The feed additive can significantly improve the stress resistance, immunity, antioxidant capacity and disease resistance of aquatic animals, and has significant economic benefits.

The application provides a crude oil direct oiling type spinning oil, a preparation method and application. The crude oil direct oiling type spinning oil comprises 65-75% of a composite smoothing agent, and the composite smoothing agent is composed of tetradecyl tetradec-9-enoate 25-35 parts and PEG-12 dipalmitate 65-75 parts. The composite smoothing agent is composed of specific compounds, so that the spinning oil can have smoothness, oil film strength and heat resistance; meanwhile, the friction coefficient of the yarn can be reduced and the uniformity of the yarn can be improved, and the quality of the yarn is good.

The present invention provides an enhanced whitening cosmetic composition comprising (A) concentrated birch sap and (B) one or more substances selected from arbutin, tranexamic acid, niacinamide, glabridin, ascorbic acid, ascorbyl glucoside, ascorbyl dipalmitate and ascorbyl tetraisopalmitate, wherein the concentrated birch sap is concentrated at a multiple of about 1.05-6 times, preferably about 1.1-5 times, and more preferably about 1.2-4 times.

The invention relates to the technical field of feed additives, in particular to a Chinese herbal medicine ultrafine powder feed additive and a preparation method thereof, the following raw materials are respectively weighed: codonopsis pilosula, acanthopanax, hawthorn, andrographis paniculata, citric acid, catechin, L-ascorbyl palmitate and reduced glutathione; immersing the codonopsis pilosula sections, the acanthopanax sections and the haw slices into enzymatic hydrolysate to carry out enzymatic hydrolysis reaction; crushing the codonopsis pilosula, the acanthopanax, the hawthorn and the andrographis paniculata sections subjected to enzymolysis by using a hammer crusher to obtain mixed powder; adding citric acid, catechin, L-ascorbyl palmitate and reduced glutathione, and mixing; the mixture is subjected to superfine grinding through a jet mill, and superfine powder is obtained; and mixing the superfine powder with hydroxypropyl-beta-cyclodextrin, adding water to prepare slurry, stirring and clathrating, and then carrying out spray drying to obtain the Chinese herbal medicine superfine powder feed additive.

The application discloses a bacteriostatic cleaning agent for pets and a preparation method thereof, and belongs to the technical field of cleaning agents.The bacteriostatic cleaning agent comprises the following components in percentage by weight: 10-20% of a surfactant, 1-5% of borage acid diglyceride monopalmitate, 5-10% of a humectant, 1-5% of a thickening agent, 0.1-0.5% of an odor inhibitor, and the balance of water.The specific compatibility of the borage acid diglyceride monopalmitate and the surfactant has the adsorption effect on dust particles and dirt with positive charges in the hair during cleaning, and the cleaning effect is improved.The repulsion between dirt and the surface of an object is increased, the dispersion of the dirt in water is facilitated, the re-deposition of the dirt is prevented, and the cleaning time is prolonged.

The application relates to the technical field of feed additives, and discloses a monensin premix and a preparation method thereof.The raw material composition of the monensin premix comprises monensin, a carrier, a surfactant, a binder, amino acid chelated trace elements, vitamin E, ascorbic acid palmitate and coenzyme Q10.The preparation method comprises the following steps: S1, stirring and mixing monensin and the carrier to prepare a mixture I; S2, dissolving the binder in a water bath at 80-100 DEG C, cooling to room temperature, adding the mixture I and the remaining raw materials, and stirring and mixing to prepare a mixture II; S3, uniformly treating the mixture II to prepare an intermediate product; and S4, preparing the intermediate product into granules by using a spray drying method, so that the monensin premix is obtained.The monensin premix prepared by the application is uniform in granularity, good in stability and uniformity, and high in drug efficacy.

The invention provides a crude oil direct oiling type spinning oil agent, a preparation method and application, the crude oil direct oiling type spinning oil agent comprises 65-75% of a composite smoothing agent, and the composite smoothing agent is composed of 25-35 parts of tetradecyl tetradecane-9-olefine acid ester and 65-75 parts of PEG-12 dipalmitate. Specific compounds are selected to form the composite smoothing agent, so that the spinning oil agent has smoothness, oil film strength and heat resistance at the same time; meanwhile, the friction coefficient of the yarn can be reduced, the uniformity of the yarn is improved, and the yarn quality is good.

The invention relates to eye drops containing umbilical cord mesenchymal stem cell exosomes. The eye drops are prepared from the following raw materials: sodium hyaluronate, an L-ascorbyl palmitate / hydroxypropyl-beta-cyclodextrin inclusion compound, panthenol, a solution containing the umbilical cord mesenchymal stem cell exosomes, water and normal saline, the concentration of the sodium hyaluronate is 0.2 to 0.6 mg / mL; the concentration of the L-ascorbyl palmitate / hydroxypropyl-beta-cyclodextrin inclusion compound ranges from 0.1 mg / mL to 0.4 mg / mL; the concentration of the panthenol is 0.2 to 1.0 mg / mL; the concentration of the umbilical cord mesenchymal stem cell exosome is 0.2 * 10 < 10 >-0.6 * 10 < 10 > parts / mL. The eye drops have good effects on treating xerophthalmia and repairing corneal epithelium injury.

The invention provides a method for preparing dehydroepiandrosterone, which comprises the following steps: S1, taking 4-androstene-3, 17-diketone as a raw material to react to generate 5-androstene-3, 17-diketone; s2, sodium acetate is dissolved in a buffer system, ascorbyl palmitate, L-glutathione, the 5-androstene-3, 17-diketone, ketoreductase, coenzyme and a coenzyme regeneration system are sequentially added for a reaction, and dehydroepiandrosterone is obtained. According to the invention, the ascorbyl palmitate, the L-glutathione and the sodium acetate cooperate to inhibit the side reaction of an intermediate product, active oxygen and the like to generate impurities, so that the purity and the yield of the dehydroepiandrosterone are improved, the purity of the final product dehydroepiandrosterone is as high as 99%, and the yield is as high as 95%.

The application discloses isobutyryl amino thiazyl resorcinol dipalmitate and a preparation method and application thereof. The compound is successfully prepared by performing an acylation reaction on isobutyryl amino thiazyl resorcinol and palmitic acid. Experiments prove that, compared with the prior art, the compound not only retains excellent whitening efficacy, but also exhibits extremely low cytotoxicity and significant soothing efficacy. The compound has whitening, soothing and high safety, overcomes the defect that traditional whitening agents are strong in irritation, and can be directly applied to cosmetics or skin external drugs, and has extremely high industrial value.

The invention belongs to the technical field of organic synthesis, and particularly relates to a method for synthesizing L-ascorbyl palmitate by an acyl chloride method. The method comprises the following steps: (1) adding palmitic acid into a mixed solvent, dropwise adding SOCl2, carrying out an acylating chlorination reaction, continuously adding L-ascorbic acid after the reaction is finished, and carrying out heating and heat preservation reaction to obtain a reaction product; (2) adding ethyl acetate and distilled water into the reaction product, putting into a separating funnel to obtain a water layer and an organic layer, extracting the water layer once by using ethyl acetate, and combining the organic layers obtained by two times; washing an organic layer with water for 3 times, then drying with anhydrous Na2SO4, and carrying out rotary evaporation to remove the organic solvent to obtain a crude product; and (3) purifying the crude product by using a silica gel chromatographic column, collecting eluent within 60-150 minutes, and performing rotary evaporation on the eluent to obtain the L-ascorbyl palmitate. The L-ascorbyl palmitate prepared by the method disclosed by the invention is high in yield and purity.

The application relates to the field of biological medicine, and discloses ascorbyl palmitate nanoliposomes capable of inducing tumor cell oncosis, a preparation method and application thereof. The nanoliposomes are constructed by inserting ascorbyl palmitate as a lipid component into a phospholipid bilayer, and are prepared by a film dispersion method from lecithin, cholesterol, pegylated phospholipid and ascorbyl palmitate. The average particle size of the nanoliposomes is 80-150 nm, the encapsulation rate is high, and the stability is good. The nanoliposomes can be administered through a tail vein, utilize the specific hydrolysis of matrix metalloproteinase MMP-2 which is highly expressed by tumor cells to hydrolyze ascorbyl palmitate, release palmitic acid and ascorbic acid, thereby inducing Caspase-independent oncosis of tumor cells, effectively overcoming apoptosis-related drug resistance, and reversing a tumor immunosuppressive microenvironment. The nanoliposomes avoid the cumulative toxicity of metal-type inducers, and provide a new safe and effective option for reversing chemotherapy resistance.

The invention discloses a melogabalin besylate solid pharmaceutical composition, a preparation and a preparation method of the melogabalin besylate solid pharmaceutical composition. The solid pharmaceutical composition comprises melogabalin besylate, and further comprises L-tartaric acid, ascorbyl palmitate and a nonionic ester compound selected from at least one of hydrogenated castor oil and glyceryl behenate. According to the melogabalin besylate solid pharmaceutical composition, due to the adoption of the combination of the L-tartaric acid, the ascorbyl palmitate and at least one nonionic ester compound selected from the hydrogenated castor oil and the glyceryl behenate, through the synergistic effect of the L-tartaric acid, the ascorbyl palmitate and the nonionic ester compound, the stability obviously superior to that in the prior art can be achieved; and the solid preparation has excellent dissolution performance.

The invention belongs to the technical field of imbibition oil extraction, and provides a water-based nano-emulsion imbibition oil displacement agent and a preparation method thereof. According to the preparation method of the water-based nano-emulsion imbibition oil displacement agent, polyoxyethylene lauryl ether, sorbitan monopalmitate, mahogany petroleum sulfonate, an oily solvent, nano silicon oxide and water are uniformly mixed through a phase transition component method to prepare the water-based nano-emulsion imbibition oil displacement agent. The preparation method of the water-based nano-emulsion imbibition oil-displacing agent can effectively improve the crude oil recovery rate of unconventional oil reservoirs.