90 results about "Palmitates" patented technology

The present invention relates to the field of pharmaceuticals and health food technology, and specifically to a method for preparing and applying red date polysaccharides. The specific technical solution comprises the following steps: a method for preparing red date polysaccharides comprises concentrating jujubes with distilled water, removing proteins, and then precipitating with ethanol to obtain a primary ethanol precipitate containing polysaccharides; dialyzing the primary ethanol precipitate, and then precipitating with ethanol to obtain a secondary ethanol precipitate containing polysaccharides, which is then freeze-dried. The extracted red date polysaccharides can improve glucose utilization, increase GLUT4 protein expression, and prevent palmitate-induced insulin resistance and muscle damage in muscle cells, and can be used to prevent, improve, or treat anabolic or muscular diseases.

The invention relates to the technical field of titanium dioxide production, in particular to high-retention and high-weather-resistance titanium dioxide as well as a preparation method and application thereof. Comprising a titanium dioxide base material and a coating layer located on the surface of the titanium dioxide base material, and the coating layer sequentially comprises an aluminum oxide film layer, a tin oxide film layer and an ascorbyl palmitate film layer from inside to outside. The preparation method comprises the following steps: preparing titanium dioxide-based material slurry, sequentially carrying out aluminum oxide coating and tin oxide coating, then carrying out water washing, flash evaporation and steam powdering, and adding ascorbyl palmitate in the steam powdering process to obtain the high-retention and high-weather-resistance titanium dioxide. The tin coating layer and the ascorbyl palmitate coating layer are introduced to the outer side of the aluminum oxide coating layer, so that the retention rate and weather resistance of titanium dioxide in paper are remarkably improved, and the use requirements of high-end paper are met; the white water treatment pressure can be reduced, and the economic benefit is improved.

The invention discloses application of a lycium barbarum Lb03G03224 gene in catalysis of esterification of free carotenoids, the nucleotide sequence of the lycium barbarum Lb03G03224 gene is as shown in SEQ ID NO: 1, and the amino acid sequence of encoded protein is as shown in SEQ ID NO: 2. According to the present invention, it is found that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate thereof can be generated when the Lb03G03224 gene is expressed in the engineering escherichia coli for generating beta-carotene, beta-cryptoxanthin and zeaxanthin, such that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate can be produced, the protein coded by the Lb03G03224 has the function of catalyzing esterification reaction of carotenoid containing free hydroxyl and fatty acid acyl donor, and has important application value in in-vitro biosynthesis of esterified carotenoid.

The invention relates to a composition containing anti-wrinkle lipidosome for cosmetic preparation and a preparation method of the composition, and belongs to the technical field of cosmetics. The invention discloses a composition containing anti-wrinkle lipidosome and a preparation method thereof. The composition comprises four plant extracts of purple coneflower, calendula officinalis, salvia officinalis and elderberry, and lipidosome consisting of lecithin, cholesterol, sphingomyelin and ascorbyl palmitate, and is supplemented with components such as a humectant and an emulsifier. According to the composition, through the synergistic effect of the plant extract and the lipidosome, the anti-wrinkle effect is enhanced, and the storage and illumination stability is improved; an extract structure is optimized by a compound fermentation process, and a liposome system is adapted; the components are safe and suitable for multiple skin types, the preparation process is compatible with industrial production, and the pain points that traditional anti-wrinkle products are poor in stability and insufficient in effect are solved.

The research finds that the SUMOylation level of the liver in a clinical specimen and an animal model of the metabolic dysfunction fatty liver disease is obviously reduced. UBC9 is used as the only key E2 ligase for SUMOylation to regulate and control the SUMOylation level. The invention discloses application of a UBC9 gene overexpression preparation in drugs for treating or preventing metabolic dysfunction fatty liver diseases. Through overexpression of liver specificity UBC9 mediated by an AAV adeno-associated virus vector or overexpression of UBC9 in HepG2 cells by a lentiviral vector, lipid deposition of a C57 mouse liver induced by high fat diet and a cell model treated by palmitate can be remarkably improved, and reduction of the SUMOylation level of the mouse liver and the human HepG2 cells under the high fat background can be reversed. Therefore, the UBC9 gene overexpression preparation can be used for developing drugs for treating metabolic dysfunction fatty liver diseases.

The invention belongs to the technical field of resveratrol synthesis, and particularly relates to a preparation method of resveratrol and application of resveratrol in meat preservation. The method comprises the following steps: taking 3, 5-dimethoxybenzoic acid as a raw material, and carrying out acylation reaction to obtain 3, 5-dimethoxybenzoyl chloride. Then reacting with p-acetoxystyrene to generate 3, 3 '-dihydroxy-3, 3'-dihydroxy-3 The preparation method comprises the following steps: taking 1, 5-dimethoxy-4 '-acetoxystilbene as a raw material, hydrolyzing and demethylating to obtain resveratrol, and preparing resveratrol lipid nanoparticle suspension by taking resveratrol, a ZIF-8 / chitosan compound, compound lipid, cholesterol, epsilon-polylysine, ascorbyl palmitate and phosphate buffer saline as raw materials. High load and controlled release of resveratrol are achieved, and the problems that resveratrol is poor in water solubility and prone to oxidation are solved.

This rotigotine-containing adhesive patch comprises a support layer and an adhesive layer, wherein the adhesive layer contains: at least one selected from the group consisting of rotigotine and pharmaceutically acceptable salts of rotigotine; a rubber-based adhesive base; and an antioxidant. The antioxidant includes propyl gallate, ascorbyl palmitate, and sodium pyrosulfite.

This invention discloses a soothing and repairing composition and its application, comprising the following raw materials: phytosterols, chamomile extract, hydrolyzed sodium hyaluronate, tocopherol, ceramide NP, triethanolamine, lactobacillus, macadamia seed oil, magnolia alcohol, matricaria flower extract, maltodextrin, lecithin, phosphatidylcholine, ascorbyl palmitate, inulin root juice, arginine / lysine polypeptide, squalane, jojoba seed oil, scutellaria baicalensis root extract, polygonum cuspidatum root extract, fructose, glycerin, p-hydroxyacetophenone, butylene glycol, acrylate / C10-30 alkanol acrylate crosspolymer, α-glucan oligosaccharide, 1,2-hexanediol, and water as the balance. Compared with the prior art, the soothing and repairing composition prepared by this invention has the effects of rapidly rebuilding the skin barrier, regulating skin immune function, improving skin microecology, synergistic effect, and rapid skin repair.

The present invention provides pharmaceutical compositions comprising a therapeutically effective dose of vitamin A palmitate; processes for their preparation, and uses and methods of treatment comprising them. The compositions provided by the present invention may be used in the treatment and / or prophylaxis of conditions and diseases caused by vitamin A deficiency.

The invention provides starch sodium octenylsuccinate-free, protein-free and lactose-free fat powder as well as a preparation method and application thereof, and belongs to the technical field of foods. The fat powder provided by the invention comprises 25%-60% of glucose syrup (in terms of solid matter), 1%-20% of maltodextrin, 20%-50% of edible plant blend oil, 0.01%-3% of mono-and diglycerol fatty acid ester, 0.01%-3% of citric acid fatty glyceride, 0.1%-1% of sodium ascorbate, 0.005%-0.02% of ascorbyl palmitate and 0.01%-1% of potassium hydroxide. The fat powder provided by the invention is free of starch sodium octenylsuccinate, protein and lactose, good in solubility, good in dispersity and high in sinking speed. After being dissolved, the emulsion is milky white, has no (or few) small oil droplet floating, no precipitate and no floating object, and after standing, the solution is not layered.

The present application relates to the field of feed additive, and discloses a feed additive, a preparation method and application thereof.The feed additive contains astaxanthin, curcumin, vitamin C palmitate, vitamin E, vitamin D3, piperine and a carrier.The preparation method comprises the following steps: mixing astaxanthin, curcumin, vitamin C palmitate, vitamin E, vitamin D3, piperine and the carrier.The feed additive can significantly improve the stress resistance, immunity, antioxidant capacity and disease resistance of aquatic animals, and has significant economic benefits.

The application provides a crude oil direct oiling type spinning oil, a preparation method and application. The crude oil direct oiling type spinning oil comprises 65-75% of a composite smoothing agent, and the composite smoothing agent is composed of tetradecyl tetradec-9-enoate 25-35 parts and PEG-12 dipalmitate 65-75 parts. The composite smoothing agent is composed of specific compounds, so that the spinning oil can have smoothness, oil film strength and heat resistance; meanwhile, the friction coefficient of the yarn can be reduced and the uniformity of the yarn can be improved, and the quality of the yarn is good.

The invention relates to the technical field of feed additives, in particular to a Chinese herbal medicine ultrafine powder feed additive and a preparation method thereof, the following raw materials are respectively weighed: codonopsis pilosula, acanthopanax, hawthorn, andrographis paniculata, citric acid, catechin, L-ascorbyl palmitate and reduced glutathione; immersing the codonopsis pilosula sections, the acanthopanax sections and the haw slices into enzymatic hydrolysate to carry out enzymatic hydrolysis reaction; crushing the codonopsis pilosula, the acanthopanax, the hawthorn and the andrographis paniculata sections subjected to enzymolysis by using a hammer crusher to obtain mixed powder; adding citric acid, catechin, L-ascorbyl palmitate and reduced glutathione, and mixing; the mixture is subjected to superfine grinding through a jet mill, and superfine powder is obtained; and mixing the superfine powder with hydroxypropyl-beta-cyclodextrin, adding water to prepare slurry, stirring and clathrating, and then carrying out spray drying to obtain the Chinese herbal medicine superfine powder feed additive.

The application discloses a bacteriostatic cleaning agent for pets and a preparation method thereof, and belongs to the technical field of cleaning agents.The bacteriostatic cleaning agent comprises the following components in percentage by weight: 10-20% of a surfactant, 1-5% of borage acid diglyceride monopalmitate, 5-10% of a humectant, 1-5% of a thickening agent, 0.1-0.5% of an odor inhibitor, and the balance of water.The specific compatibility of the borage acid diglyceride monopalmitate and the surfactant has the adsorption effect on dust particles and dirt with positive charges in the hair during cleaning, and the cleaning effect is improved.The repulsion between dirt and the surface of an object is increased, the dispersion of the dirt in water is facilitated, the re-deposition of the dirt is prevented, and the cleaning time is prolonged.

The application relates to the technical field of feed additives, and discloses a monensin premix and a preparation method thereof.The raw material composition of the monensin premix comprises monensin, a carrier, a surfactant, a binder, amino acid chelated trace elements, vitamin E, ascorbic acid palmitate and coenzyme Q10.The preparation method comprises the following steps: S1, stirring and mixing monensin and the carrier to prepare a mixture I; S2, dissolving the binder in a water bath at 80-100 DEG C, cooling to room temperature, adding the mixture I and the remaining raw materials, and stirring and mixing to prepare a mixture II; S3, uniformly treating the mixture II to prepare an intermediate product; and S4, preparing the intermediate product into granules by using a spray drying method, so that the monensin premix is obtained.The monensin premix prepared by the application is uniform in granularity, good in stability and uniformity, and high in drug efficacy.

The invention relates to eye drops containing umbilical cord mesenchymal stem cell exosomes. The eye drops are prepared from the following raw materials: sodium hyaluronate, an L-ascorbyl palmitate / hydroxypropyl-beta-cyclodextrin inclusion compound, panthenol, a solution containing the umbilical cord mesenchymal stem cell exosomes, water and normal saline, the concentration of the sodium hyaluronate is 0.2 to 0.6 mg / mL; the concentration of the L-ascorbyl palmitate / hydroxypropyl-beta-cyclodextrin inclusion compound ranges from 0.1 mg / mL to 0.4 mg / mL; the concentration of the panthenol is 0.2 to 1.0 mg / mL; the concentration of the umbilical cord mesenchymal stem cell exosome is 0.2 * 10 < 10 >-0.6 * 10 < 10 > parts / mL. The eye drops have good effects on treating xerophthalmia and repairing corneal epithelium injury.

The invention provides a method for preparing dehydroepiandrosterone, which comprises the following steps: S1, taking 4-androstene-3, 17-diketone as a raw material to react to generate 5-androstene-3, 17-diketone; s2, sodium acetate is dissolved in a buffer system, ascorbyl palmitate, L-glutathione, the 5-androstene-3, 17-diketone, ketoreductase, coenzyme and a coenzyme regeneration system are sequentially added for a reaction, and dehydroepiandrosterone is obtained. According to the invention, the ascorbyl palmitate, the L-glutathione and the sodium acetate cooperate to inhibit the side reaction of an intermediate product, active oxygen and the like to generate impurities, so that the purity and the yield of the dehydroepiandrosterone are improved, the purity of the final product dehydroepiandrosterone is as high as 99%, and the yield is as high as 95%.

The application discloses isobutyryl amino thiazyl resorcinol dipalmitate and a preparation method and application thereof. The compound is successfully prepared by performing an acylation reaction on isobutyryl amino thiazyl resorcinol and palmitic acid. Experiments prove that, compared with the prior art, the compound not only retains excellent whitening efficacy, but also exhibits extremely low cytotoxicity and significant soothing efficacy. The compound has whitening, soothing and high safety, overcomes the defect that traditional whitening agents are strong in irritation, and can be directly applied to cosmetics or skin external drugs, and has extremely high industrial value.

The application relates to the field of biological medicine, and discloses ascorbyl palmitate nanoliposomes capable of inducing tumor cell oncosis, a preparation method and application thereof. The nanoliposomes are constructed by inserting ascorbyl palmitate as a lipid component into a phospholipid bilayer, and are prepared by a film dispersion method from lecithin, cholesterol, pegylated phospholipid and ascorbyl palmitate. The average particle size of the nanoliposomes is 80-150 nm, the encapsulation rate is high, and the stability is good. The nanoliposomes can be administered through a tail vein, utilize the specific hydrolysis of matrix metalloproteinase MMP-2 which is highly expressed by tumor cells to hydrolyze ascorbyl palmitate, release palmitic acid and ascorbic acid, thereby inducing Caspase-independent oncosis of tumor cells, effectively overcoming apoptosis-related drug resistance, and reversing a tumor immunosuppressive microenvironment. The nanoliposomes avoid the cumulative toxicity of metal-type inducers, and provide a new safe and effective option for reversing chemotherapy resistance.

The invention belongs to the technical field of imbibition oil extraction, and provides a water-based nano-emulsion imbibition oil displacement agent and a preparation method thereof. According to the preparation method of the water-based nano-emulsion imbibition oil displacement agent, polyoxyethylene lauryl ether, sorbitan monopalmitate, mahogany petroleum sulfonate, an oily solvent, nano silicon oxide and water are uniformly mixed through a phase transition component method to prepare the water-based nano-emulsion imbibition oil displacement agent. The preparation method of the water-based nano-emulsion imbibition oil-displacing agent can effectively improve the crude oil recovery rate of unconventional oil reservoirs.

The invention discloses a rhizoma polygonati anti-aging extract and a preparation method thereof. The method comprises the following steps: pre-treating raw materials by adopting a composite cleaning agent containing green tea polyphenol and a ginger extract; soaking with a sugar protecting agent containing fructo-oligosaccharide and L-ascorbyl palmitate; carrying out nine-steaming nine-drying treatment after gradient ultrasonic cleaning, and recovering polysaccharide in condensed water through spiral condensation, centrifugation and ceramic membrane filtration in the steaming process; the preparation method comprises the following steps: extracting with hot water, heating and concentrating, mixing the obtained extract with polysaccharide recovered from condensed water, compounding with a cistanche deserticola extract according to a ratio of 3: 2, mutually dissolving with a composite cosolvent, carrying out gelatin-Arabic gum microencapsulation, and finally granulating with a slow-release matrix. According to the invention, the problems of loss of pretreatment polysaccharide, waste of active ingredients of condensed water, poor stability of terminal products, asynchronous release and the like are solved through a full-chain technology, and the retention rate, the stability and the anti-aging synergistic effect of the active ingredients are remarkably improved.

The application provides a kind of tea polyphenol ester-RNA self-assembly and hybrid nanovesicle of probiotic outer membrane vesicle and preparation method thereof, which first adjusts the hydrophilicity and hydrophobicity of tea polyphenol EGC through molecular modification strategy, and the EGC palmitate obtained by modification can directly wrap RNA and self-assemble into tea polyphenol ester-RNA nanovesicle, which has superior encapsulation capacity. Further introduce OMVs as intestinal targeted delivery carrier and fuse with RNA-tea polyphenol nanovesicle to form a structure stable hybrid vesicle. The hybrid vesicle of the application ingeniously integrates the advantages of both sides: tea polyphenol ester-RNA nanovesicle ensures efficient encapsulation of RNA, and OMVs provide natural protection for its translocation through gastrointestinal tract, and promote intestinal cell uptake with its inherent bioadhesion. This strategy can effectively promote the encapsulation and stabilization of oral RNA delivery.

The invention relates to a composition suitable for an oil-in-water sunscreen system and application of the composition. The composition is prepared from polysorbate, polyethylene glycol monomethyl ether polydimethylsiloxane, dextrin palmitate and hydrolyzed royal jelly protein. The composition is safe and non-irritant in formula, has excellent sunscreen performance, is easier to prepare a stable oil-in-water sunscreen product, does not need to be removed by a cleaning product, and can be washed by clean water.

Stabilized oils including an edible oil and an antioxidant composition comprising α-lipoic acid and least one of ascorbic acid, ascorbyl palmitate, green tea extract, lecithin, and rosemary extract or at least one of 1,2,4-benzenetriol, carnosic acid, dihydromyricetin, dihydrorobinetin, epigallocatechin, gallic acid, 3-hydroxytyrosol, myricetin, and nepodin, and methods of preparing such stabilized edible oils. The stabilized oils may have an Oxidative Stability Index (“OSI”) at 110° C. of at least 30 hours.

The invention relates to the technical field of medicines, in particular to triamcinolone acetonide palmitate nano-emulsion as well as a preparation method and application thereof. The composition comprises a water phase and an oil phase, the oil phase comprises triamcinolone acetonide palmitate, a surfactant, oil and a cosurfactant; the water phase comprises an osmotic pressure regulator and a charge modifier. In the triamcinolone acetonide palmitate nano-emulsion, the content ratio of the oil to the surfactant is (3: 1)-(1: 1). According to the preparation method of the triamcinolone acetonide palmitate nano-emulsion provided by the invention, a phase transformation method is adopted, and the average particle size of the triamcinolone acetonide palmitate nano-emulsion is accurately controlled by changing the dosage of the oil phase and the surfactant, so that the triamcinolone acetonide palmitate nano-emulsion suitable for eye iontophoresis is obtained. Meanwhile, it is further found that the permeability of the triamcinolone acetonide palmitate nano-emulsion can be remarkably enhanced by adding cations into the triamcinolone acetonide palmitate nano-emulsion, and the delivery efficiency is enhanced.

The application belongs to the technical field of compositions, and provides a moisturizing eye composition, a preparation method and application thereof. The moisturizing eye composition provided by the application is combined by soybean lecithin, retinol palmitate liposome, lutein, oligomeric hyaluronic acid and ethylenediaminetetraacetic acid in a specific ratio, and good synergies can be achieved among the components, the effect of relieving asthenopia, protecting eyesight and maintaining normal vision is improved, and the effect of improving and relieving the symptoms of dry eyes and dry eyes caused by various reasons (such as fatigue, wearing contact lenses, using electronic products, overuse of eyes, etc.) is improved.

The invention relates to nutritional soft sweets containing lutein ester microcapsule powder and a preparation method of the nutritional soft sweets. The soft sweets comprise the following raw materials in percentage by weight: 15-20% of lutein ester microcapsule powder, 60-70% of soft sweets matrix, 1-3% of auxiliaries and the balance of drinking water, the lutein ester microcapsule powder is prepared from the following raw materials in percentage by weight: 10 to 15 percent of lutein ester crystals, 10 to 12 percent of vegetable oil, 0.5 to 1 percent of ascorbyl palmitate, 8 to 12 percent of starch octenyl succinate, 5 to 8 percent of succinylated black bean protein, 1.5 to 2.5 percent of blueberry polysaccharide and the balance of drinking water. The soft sweets provided by the invention can realize long-acting stability of lutein ester, and finally guarantee persistence of an eye protection effect.

The present invention relates to the field of optical cable technology, and specifically to a non-metallic fire-resistant, rat-proof and ant-proof optical cable and a processing method. A non-metallic fire-resistant, rat-proof and ant-proof optical cable comprises a cable core, an insulation layer, a sheath layer and a rat-proof and ant-proof layer arranged in sequence from the inside to the outside. The present invention reacts palmitic acid and capsaicin to form capsaicin palmitate. Palmitic acid combines with capsaicin, and capsaicin can attack mice through a group. The slightly volatile odor of palmitate enhances the rat-repelling effect, thereby achieving a repelling effect. In addition, the odor emitted by the palmitate formed by palmitic acid and capsaicin also has a certain repelling effect on ants. In addition, the reaction between palmitic acid and capsaicin will not destroy the group of capsaicin used to repel rats and ants, and its rat-repelling irritation is retained. The fat-soluble structure of capsaicin palmitate can slowly release active ingredients in the coating, and permanently repel rats and ants from gnawing on the optical cable.

The application discloses a process method for co-production of L-ascorbyl palmitate and biodiesel, which comprises the following steps: performing a first enzyme catalysis reaction on L-ascorbic acid and palm oil to obtain a first enzyme catalysis mixture; performing layer separation and vacuum distillation treatment on the first enzyme catalysis mixture to obtain a first enzyme catalysis product; performing a second enzyme catalysis reaction on the first enzyme catalysis product to obtain a second enzyme catalysis mixture; and performing distillation treatment on the second enzyme catalysis mixture under online dehydration conditions to obtain L-ascorbyl palmitate and biodiesel; the application utilizes the solubility of L-ascorbic acid in short-chain alcohol, promotes mutual solubility of L-ascorbic acid and palm oil, adopts two-step enzyme catalysis reaction under mild conditions, realizes reaction of L-ascorbic acid and palm oil catalyzed by lipase to generate L-ascorbyl palmitate, and realizes reaction of palm oil and short-chain alcohol catalyzed by lipase to generate biodiesel, so that integrated co-production of various high-value-added products is realized.