22 results about "Monolaurin" patented technology

The application relates to the technical field of cosmetics, in particular to a water-in-oil system makeup primer and a preparation method thereof. The water-in-oil system makeup primer comprises the following components in parts by weight: cosmetic-grade purified water, cetyl PEG / PPG-10 / 1 dimethicone, dimethicone, isononyl isononanoate, synthetic wax, microcrystalline wax, glycerol, 1,3-propanediol / octyldodecanol / ethylhexylglycerin, butylene glycol, sodium chloride and a polyoxyethylene (20) sorbitan monolaurate-polyoxypropylene (4) sorbitan monolaurate compound. The water-in-oil system makeup primer provided by the application can realize 80% high-aqueous-phase stable bearing, provide sufficient moisturizing reserves for dry skin, realize instant film forming and water locking during smearing, improve the water retention rate to more than 85%, solve the problem of water supplement efficacy attenuation, thereby realize the dual effects of instant water locking and long-acting moisturizing, and resolve the contradiction between water locking and skin feeling.

The present invention discloses a novel stable, single phase aqueous suspension for nasal administration to treat bacterial sinusitis. The composition takes azithromycin dihydrate as an active ingredient, and adopts a suspending agent system to prevent phase separation during storage. Embodiments include a formulation comprising a sorbitan monolaurate, or a combination of chitosan and a sorbitan monolaurate, to maintain the stability of the suspension. The present invention has a variety of advantages, including local delivery of azithromycin to an infected site, which can reduce systemic exposure and associated side effects compared to oral formulations.

This invention belongs to the field of pharmaceutical chemistry technology, specifically relating to a monopravir-caprolactam cocrystal, its preparation method, and its applications. The monopravir-caprolactam cocrystal is composed of monopravir and caprolactam in a molar ratio of 1:1.9-2.1. X-ray powder diffraction was performed using Cu-Kα radiation, with angles expressed as 2θ±1, at 6.91, 7.09, 8.38, 11.24, 12.52, 13.26, 13.87, 14.24, 15.22, 16.82, 17.31, and 1... Characteristic peaks are observed at 9.73, 20.22, 20.53, 20.84, 21.90, 22.28, 22.52, 22.95, 23.51, 23.75, 24.00, 24.31, 24.86, 25.35, 26.44, 27.41, 28.02, 28.69, 29.22, 29.84, and 30.33. Monopravir-caprolactam cocrystals can be successfully prepared by grinding and / or solution methods, and grinding and / or melting methods. The preparation process is simple, and the obtained product has high purity. Characterization has confirmed it to be a new cocrystal. Powder flowability and tableting tests revealed that the monopravir-caprolactam cocrystals provided by this invention have better flowability and tableting properties compared to monopravir crystal form I, meeting the requirements of formulation and manufacturing processes.

This invention relates to ophthalmic compositions comprising troxerutin and a surfactant selected from polyoxyethylene 35 castor oil, polyoxyethylene 40 hydrogenated castor oil, polyoxyethylene (20) sorbitan monooleate, polyoxyethylene (20) sorbitan monolaurate, and mixtures thereof, wherein the weight ratio of troxerutin to the surfactant is from 0.02:1 to 100:1, wherein the surfactant is present in an amount of up to 7% by weight relative to the total weight of the composition, and wherein the composition is in the form of a solution, suspension, or gel. The invention also relates to the compositions for treating dry eye disease.

The embodiment of the invention discloses a composite freeze-drying protective agent based on CRISPR-Cas13a, a microsphere molecular diagnostic reagent and a preparation method. The composite freeze-drying protective agent comprises a vitrification matrix component, a structure support component, a protein aggregation inhibitor and a surfactant, the vitrification matrix component comprises mannitol and trehalose, and the mass ratio of mannitol to trehalose is (3-7): (3-7); the structural support component comprises any one of PEG8000, PEG6000 and PEG4000 and any one of glucan 10000, glucan 8000 and glucan 20000, and the mass ratio of the PEG8000 to the PEG6000 to the glucan 8000 to the glucan 20000 is (1-5): (1-5); the protein aggregation inhibitor is bovine serum albumin, and the surfactant is polyoxyethylene sorbitan monolaurate; the mass ratio of the structure supporting component to the vitrification matrix component is (1-5): (3-7), the mass ratio of the protein inhibitor to the structure supporting component is (0.01-1): (2-10), and the mass ratio of the surfactant to the structure supporting component is (0.001-0.1): (2-10).

The application discloses a method for continuously synthesizing monolara. Cytidine and acylation reagent are dissolved in a reaction solvent, and acylation is selectively carried out on the fifth site of the cytidine in a micro-channel reactor to obtain 5'-O-methyl propenyl cytosine nucleoside; through extraction and pH adjustment, the solvent is replaced by water to obtain 5'-O-methyl isopropyl cytosine nucleoside aqueous solution; the obtained aqueous solution is pumped into a fixed bed reactor, hydrolysis is completed, and then a hydroxylamine reagent is pumped in; after uniform mixing, the mixture is pumped into a micro-channel reactor to complete hydroxylamine reaction, and monolara aqueous solution is obtained; finally, monolara product is obtained through concentration, cooling, filtration, washing and drying. The application successfully realizes two-step continuous process for preparing monolara, and greatly shortens the time required for synthesizing monolara compared with a kettle type reaction.

The present application relates to a kind of waterproof antifouling wrinkle-resistant high twist cashmere wool yarn, and the high twist yarn of cashmere fiber and wool fiber blend is treated to obtain by composite finishing liquid;The composite finishing liquid includes wool peptide grafting polysiloxane copolymer, multiple anchor, arabic gum grafting epichlorohydrin, wool keratin hydrolysate, polyoxyethylene sorbitan monolaurate, polyglyceryl-3 diisostearate and deionized water.The composite finishing liquid of the present application uses wool peptide grafting polysiloxane copolymer as waterproof antifouling agent, and is homologous compatible with cashmere wool fiber, avoids the hand feeling rigid caused by traditional fluorine reagent;Collaborate arabic gum grafting epichlorohydrin wrinkle-resistant enhancer, and synergistically strengthen wrinkle-resistant performance with high twist structure, simultaneously realize the firm adhesion of functional layer by multiple anchor, give consideration to waterproof antifouling and wrinkle-resistant effect, solve the problem of traditional fluorine waterproof agent hand feeling rigid, function easy to fall off, wrinkle resistance decreases.

The invention includes a method for treating a vascular abnormality of the skin of a human subject, comprising topically administering to the abnormality a composition comprising: a) Rapamycin; b) Monolaurin and Monomyristin as vehicle; and c) water; once daily at a rate of: d) 4 -8 mg Rapamycin / cm2; and / or e) 1-6 mg Rapamycin.

An example of the present invention provides a fuel additive composition, which includes a mixture of a mixture of tert-butylhydroquinone, a catalyst, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, a lubricant, and a lubricant. The CAS number is 1948-33-0), and the CAS number is 1948-33-0), and the CAS number is 1948-33-0), and the CAS number is 1948-33-0, and the CAS number is 1948-33-0; the invention relates to a calcium acetylacetonate hydrate and a preparation method thereof. The calcium acetylacetonate hydrate is characterized in that the CAS number is 61789-86-4. The invention relates to a high-base-number petroleum calcium sulfonate, which is characterized in that the CAS number is 345909-31-1), and the high-base-number petroleum calcium sulfonate is prepared by the following steps of: preparing a high-base-number petroleum calcium sulfonate, a high-base-number petroleum calcium sulfonate and a high-base-number petroleum calcium sulfonate; the CAS number is 68783-96-0), and the content of sorbitan monolaurate (Sorbitan monolaurate; the CAS serial number is 1338-39-2) and 2-ethylhexyl nitrate ester (2-ethylhexyl nitrate; the CAS serial number is 1338-39-2) and 2-ethylhexyl nitrate ester (2-ethylhexyl nitrate; and the CAS serial number is 27247-96-7). The fuel additive composition according to one embodiment of the present invention can be added to various fuels such as gasoline, light oil, heavy oil and the like to improve the combustion efficiency at the time of fuel combustion while significantly reducing the generation of atmospheric pollutants such as particulate matter (PM), carbon monoxide (CO), hydrocarbon (HC), nitrogen oxide (NOx) and the like.

The present invention provides a composition that suppresses the chemical decomposition of rapamycin during storage. [Solution] A local therapeutic composition, a) Rapamycin as the active ingredient; b) Vehicles including the following: ○Monolaurin, for example, as glyceryl monolaurate; and ○Monomyristate, for example, as glyceryl monomyristate; and c) Water as a solvent A composition containing the following:

To propose a method for effectively reducing the amount of fluorine-containing emulsifiers that may remain in aqueous emulsion polymerization solutions of fluoropolymers, including fluoroelastomers and perfluoroelastomers. [Solution] The following steps: A process of passing a weakly acidic aqueous solution through a hydroxide ion type strongly basic anion exchange resin. A step of adding polyoxyethylene (20) sorbitan monolaurate to an aqueous dispersion of fluoropolymer containing a fluorine-containing emulsifier, followed by A step to obtain an aqueous fluoropolymer dispersion by passing a fluoropolymer aqueous dispersion containing polyoxyethylene (20) sorbitan monolaurate and a fluorine-containing emulsifier through a strongly basic anion exchange resin through which the weakly acidic aqueous solution has been passed. A method for producing an aqueous dispersion of a fluoropolymer containing at least [a specific substance] is provided. Furthermore, a method for producing a fluoropolymer is provided for obtaining a fluoropolymer from the obtained aqueous dispersion of a fluoropolymer.

This invention relates to a wall painting coating and its preparation method, belonging to the field of polymer coating technology. The wall painting coating of this invention comprises the following components in parts by weight: 35-45 parts of waterborne acrylic copolymer emulsion; 15-25 parts of waterborne iron oxide red paste; 1.8-2.5 parts of silane-modified attapulgite clay; 0.4-0.6 parts of associative polyurethane thickener; 0.6-1.0 parts of wood fiber; 0.8-1.2 parts of wetting and dispersing agent; 0.15-0.2 parts of defoamer; 2.0-3.0 parts of film-forming aid; and 31-33 parts of water. The wetting and dispersing agent is sorbitan monolaurate, N,N-bis(2-hydroxypropyl)-dodecanoamide, or N-tris(hydroxymethyl)methyl-citrate monohydrazide amide.

The invention discloses an emulsifier, a preparation method and an application method, the emulsifier has the advantages of low cost, environmental protection, food safety and easiness in use, and the problems of high consumption, high cost and potential food safety of traditional milk in coffee art practice are solved. The emulsifier is prepared by mixing polyoxyethylene (20) sorbitan monolaurate and polyethylene glycol 400 monooleate according to a specific mass ratio, and can simulate the physical characteristics, including density, stability and milk foam quality, of the whipped milk at normal temperature. Through an accurate formula and a simple preparation process, the emulsifier disclosed by the invention can provide experience similar to that of real milk in the coffee art, meanwhile, the dependence on milk is reduced, the food waste is reduced, and the practice efficiency of coffee professionals is improved. Besides, the main component of the emulsifier is a food additive, so that the emulsifier is safer to use and does not threaten human health, and the environmental problem possibly caused by using chemical raw materials is also avoided.

A reactive calcium oxide (CaO) catalyst for catalytic applications is disclosed. The catalyst comprises calcium oxide particles exhibiting rod-like and dumbbell-shaped morphologies and particle characteristics associated with enhanced catalytic activity in monolaurin synthesis. The catalyst possesses reduced particle agglomeration and increased accessible surface area relative to calcium oxide materials produced under non-optimized calcination conditions. In certain embodiments, the catalyst exhibits an average particle size in the nanometer range suitable for glycerolysis reactions. The reactive calcium oxide catalyst may be derived from thermal decomposition of calcium hydroxide precursor material and is suitable for use in monolaurin production and related catalytic processes.

Pharmaceutical aerosol formulations containing pre-micronized albuterol sulfate, high amount of green propellant trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), and a surfactant (polysorbate 80 (polyoxyethylene (20) sorbitan monooleate), polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate), polyethylene glycol 1000, span 85 (sorbitan trioleate), polyvinylpyrrolidone K25, or their combination) in a pressurized metered dose inhaler are described. The formulations do not use any co-solvent, i.e., they are co-solvent-free (e.g., free of ethanol, glycerol, propylene glycol, and a combination thereof). The formulations provide highly efficient delivery, through metered dose inhaler (MDI), of pre-micronized albuterol particles into the patients' respiratory tracts and have the advantages of high efficacy, improved safety, and a low global warming potential (GWP) for environmental impact.

The present invention provides compositions and methods for treating a subject diagnosed with ASD. In preferred embodiments, the subject compositions comprise tellimagrandin II, glycyrrhizin, monolaurin, selenium, honokiol, a probiotic, and one or more biological amphiphilic molecules, which when administered to a subject, can support immune and / or digestive health, and suppress and / or disable viral pathogenic agents in the body.

Provided are: an inkjet ink for a solid preparation, the inkjet ink having exceptional dischargeability from a nozzle of an inkjet head when applied using an inkjet method; a solid preparation; and a method for producing a solid preparation. An inkjet ink for a solid preparation according to the present invention contains ethanol that serves as the main solvent, an active ingredient that is soluble in ethanol, and a viscosity adjuster that adjusts the viscosity of the inkjet ink for a solid preparation, the viscosity modifier being at least one selected from the group consisting of polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyethylene glycol sorbitan monooleate, polyethylene glycol, lauromacrogol, polyvinylpyrrolidone having a K value of 25 or lower, and shellac.

The invention relates to the technical field of cosmetics, in particular to water-in-oil system pre-makeup cream and a preparation method thereof. The water-in-oil system pre-makeup cream comprises the following components in parts by weight: cosmetic-grade purified water; and cetyl PEG (Polyethylene Glycol) / PPG-10 / 1 polydimethylsiloxane. A polydimethylsiloxane; isononyl isononanoate; synthetic wax; microcrystalline wax; glycerol; 1, 3-propylene glycol / caprylyl glycol / ethylhexylglycerin; butanediol; sodium chloride; and a compound of polyoxyethylene (20) sorbitan monolaurate and polyoxypropylene (4) sorbitan monolaurate is prepared from the polyoxyethylene (20) sorbitan monolaurate and the polyoxypropylene (4). The water-in-oil system pre-makeup cream provided by the invention can realize 80% high water phase stable bearing, and provides sufficient moisturizing reserve for dry skin; meanwhile, in the smearing process, instant film forming and water locking can be achieved, the water retention rate is increased to 85% or above, and the problem that the water supplementing effect is attenuated is solved, so that the double effects of instant water locking and long-acting moisturizing are achieved, and the contradiction between water locking and skin feeling is eliminated.

The utility model discloses a granulation tower for improving the distribution state of monolauric acid glyceride particles, which comprises a tower body, a feed port is arranged on the upper side of the tower body, the lower end of the feed port is positioned in the tower body and is fixedly connected with a material distribution plate, and a granulation plate is fixedly connected in the tower body positioned on the lower side of the material distribution plate. A spray pipe is fixedly connected to the tower body between the granulation plate and the distribution plate, a mounting plate is fixedly connected to the rear side of the tower body, a bearing plate is slidably connected in the mounting plate, the bearing plate is slidably connected with the granulation plate, an electric telescopic rod is fixedly connected to the outer side of the mounting plate, and the output end of the electric telescopic rod is fixedly connected with the bearing plate; a first sieve plate and a second sieve plate are fixedly connected in the tower body on the lower side of the granulation plate, vibration motors are fixedly connected to the lower sides of the first sieve plate and the second sieve plate, discharge ports are formed in the two sides of the tower body, guide plates are fixedly connected in the discharge ports, and an air feeder is fixedly connected to the bottom in the tower body. By means of the structure, particles which are not uniform in size and broken can be screened out, and the production quality is improved.

A topical mosquito repellent and sunscreen product includes active and inert ingredients. The active ingredients include geraniol, clove oil, and rosemary oil. The inert ingredients include water, mineral oil, zinc oxide, beeswax, monolaurin, triethyl citrate, zeolite, lecithin, and xanthan gum. The mosquito repellent and sunscreen composition is provided as a lotion.

The invention includes a method for treating a vascular abnormality of the skin of a human subject, comprising topically administering to the abnormality a composition comprising: a) Rapamycin; b) Monolaurin and Monomyristin as vehicle; and c) water; once daily at a rate of: d) 4 -8 mg Rapamycin / cm2; and / or e) 1-6 mg Rapamycin.