Scar repair material

A technology for repairing materials and scars, which is applied in medical science, surgery, etc., and can solve the problem of fibroblasts and collagen fibers not having a clear direct effect, no bacteria killing or inhibiting effect on the scar surface, and small cracks and infections that are not easy to detect with the naked eye. and other problems to achieve the effect of accelerating healing, good repairing effect, and reducing the proportion

Active Publication Date: 2012-04-11
TIANJIN JIASHITANG SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this type of product has the following disadvantages: a, passively seals moisture, does not have the function of actively moisturizing scarred skin, and passively repairs scars by hydrating scarred skin, rather than actively promoting the change of scarred skin structure; b, silicon The gel seals the scar skin from external bacterial infection, but does not actively kill or inhibit the bacteria on the surface of the scar; c, the skin epidermis on the surface of the scar body (scar or keloid after burn) is actually incomplete, and it is likely There are small cracks and infections that are not easy to detect with the naked eye, and simple silicone gel preparations cannot repair these small inflammations; d. It has no clear direct effect on inhibiting fibroblasts and collagen fibers in the scar body

Method used

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Examples

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Embodiment 1

[0021] A kind of scar repairing material, is made with following method: be that the degree of substitution is 60% carboxymethyl chitosan 1g is dissolved in 60g water under stirring, adds the polyoxyethylene sorbitan monolauric acid that plays emulsifying effect 2 g of ester, 5 g of moisturizing agent glycerin, and mix well to obtain a transparent gel-like solution; under homogenization, add 40 g of polydimethylsiloxane with a kinematic viscosity of 40,000 cst into the gel-like solution, mix evenly, and obtain A scar repair material.

Embodiment 2

[0023] A kind of scar repairing material, is made with following method: be that the degree of substitution is 90% carboxymethyl chitosan 4g is dissolved in 80g water under stirring, adds the polyoxyethylene sorbitan monolauric acid that plays emulsifying effect 2g of ester, 8g of glycerin with moisturizing effect, mix well to get a transparent gel-like solution; under homogenization, 50g of polydimethylsiloxane with a kinematic viscosity of 100000cst is added to the gel-like solution, mixed Evenly, a kind of scar repair material can be obtained.

Embodiment 3

[0025] A kind of scar repairing material, is made with following method: 0.5 g of carboxymethyl chitosan of degree of substitution 100% is dissolved in 10 g of water under stirring, adds the polyoxyethylene sorbitan monolauric acid that plays emulsifying effect 1g of ester, 10g of glycerin with moisturizing effect, and mix well to obtain a transparent gel-like solution; under homogeneous condition, add 20g of polydimethylsiloxane with a kinematic viscosity of 80000cst into the gel-like solution, mix evenly, That is, a scar repair material is obtained.

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Abstract

The invention discloses a scar repair material. A preparation method comprises the following steps of: dissolving water-soluble chitosan in water or dissolving chitosan with the deacetylation degree of 75 to 97 percent in an acetic acid aqueous solution under stirring, adding polyoxyethylene sorbitan monolaurate with an emulsifying effect and glycerin with a moisturizing effect, and uniformly mixing to obtain a transparent gel-like solution; and adding polydimethylsiloxane into the gel-like solution under homogenizing, and uniformly mixing to obtain the scar repair material. The scar repair material can actively and passively moisture skin, has a hydration effect on scar skin, has a good repair effect, has an effect of resisting and inhibiting bacteria, has a good effect of resisting and inhibiting the bacteria on the surfaces of scars and outside the scars, has an effect of accelerating skin wound healing, can have a good effect of repairing and protecting fine cracks on the surfacesof the scars, and can inhibit the secretion of collagen type I in keloid skin to reduce the proportion of the collagen type I or collagen type III.

Description

technical field [0001] The invention relates to a medical biological material, in particular to a scar repair material. Background technique [0002] Most of the scar treatment products currently on the market are single-component silicone scar repair stickers or silicone gel scar repair creams made of polysiloxane. The principle of such products for scar repair is to seal the skin with silicone , Form a breathable and impermeable protective film, prevent the moisture in the scar from dissipating, and form hydration with the skin to repair the scar. However, this type of product has the following disadvantages: a, passively seals moisture, does not have the function of actively moisturizing scarred skin, and passively repairs scars by hydrating scarred skin, rather than actively promoting the change of scarred skin structure; b, silicon The gel seals the scar skin from external bacterial infection, but does not actively kill or inhibit the bacteria on the surface of the sca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/04
Inventor 王倩丁利营
Owner TIANJIN JIASHITANG SCI & TECH
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