208 results about "Skin structure" patented technology

The invention relates to the field of biomedical materials, in particular to a novel composite collagen material for wound repair, and particularly relates to a preparation method of the novel composite collagen material containing 21-type recombinant humanized collagen (ColpepA1 21) and application of the novel composite collagen material in wound repair. The ColpepA1 21 is used for remarkably promoting key biological reactions in the wound healing process, including accelerating cell migration, enhancing the skin hydration state and barrier function and improving the stability and elasticity of the skin structure, a novel composite collagen material is developed, wound healing and cell regeneration can be effectively promoted, and oxidative damage can be relieved.

The invention relates to the technical field of skin care, in particular to a collagen composition with anti-wrinkle and repairing effects and a preparation method. Comprising 1.5-4.5 parts of mixed collagen, 2.5-5 parts of mixed polypeptide and 4-8 parts of mixed extract, wherein the mixed extract comprises 1-2 parts of centella asiatica extract, 1-2 parts of polygonum cuspidatum root extract, 1-2 parts of bilberry fruit extract and 1-2 parts of bidens pilosa extract; the collagen is directly supplied to the skin to supplement collagen, and is mainly used for repairing the skin structure, increasing the density, elasticity and compactness of the skin and remarkably improving fine wrinkles and looseness; the polypeptide inhibits the expression of MMP-1; the natural plant active ingredients promote the expression of TGF-beta, enhance the activity of fibroblasts, accelerate the synthesis of collagen, prevent excessive oxidation of skin, repair skin inflammation, activate cell energy and delay skin aging.

The invention discloses a multifunctional aircraft skin bionic heterostructure and a preparation method thereof, belongs to the technical field of aerospace, and aims to solve the problem that a traditional aircraft skin structure is difficult to synergistically realize impact resistance, sound absorption, noise reduction and electromagnetic shielding, and a multifunctional composite skin protection structure is designed in a breakthrough manner. Through collaborative innovation of a bionic framework and a functional material, triple optimization of mechanical-acoustic-electromagnetic characteristics is realized. A bionic skeleton structure with outstanding mechanical properties is obtained through a layered annular structure of a glass sponge skeleton and a hierarchical structure design of a thighbone, and the bionic skeleton structure is combined with modified polyurethane foam with excellent sound absorption performance and electromagnetic shielding performance to obtain a multifunctional heterostructure with impact resistance, noise reduction and electromagnetic shielding.

The invention relates to a fiber continuous longitudinal and transverse reinforced integral composite material skin structure which is formed by co-bonding an upper skin (3), a lower skin (1) and a longitudinal and transverse reinforced structure (2). The invention further relates to a forming method of the fiber continuous longitudinal and transverse reinforced integral composite material skin structure. The forming method comprises the step of forming the longitudinal and transverse reinforced structure (2). Paving the skin and positioning the longitudinal and transverse reinforcing structure (2); and curing the paved fiber continuous longitudinal and transverse reinforced integral composite material skin structure, machining a circular opening in each of the left side and the right side of the longitudinal and transverse reinforced structure (2), and completing the whole forming process of the fiber continuous longitudinal and transverse reinforced integral composite material skin structure. The skin structure is light in weight and continuous in fiber, the structural strength is effectively enhanced through integral structure cementing co-curing forming, the integral structure is more excellent in rigidity performance, and the embedded longitudinal and transverse reinforcing structure is high in size and position precision.

The present invention relates to the field of biomedical materials, particularly to a novel composite collagen material for wound repair, and more specifically to a method for preparing a novel composite collagen material comprising recombinant humanized collagen type 21 (ColpepA1 21) and its use in wound repair. The present invention utilizes ColpepA1 21 to significantly promote key biological reactions in the wound healing process, including accelerating cell migration, enhancing skin hydration and barrier function, and improving the stability and elasticity of skin structure. The resulting novel composite collagen material effectively promotes wound healing and cell regeneration, alleviating oxidative damage.

The invention belongs to the field of cellulose materials, and particularly relates to a functional cellulose fiber as well as a preparation method and application thereof. The functional cellulose fiber comprises a core structure formed by fiber raw materials and a skin layer structure formed by functional components, the skin layer structure covers the surface of the core structure, and the functional components are selected from one or more of silk fibroin, sodium alginate and soybean protein. The cellulose functional fiber with the skin-core structure is prepared, the core layer is a cellulose layer, high strength is provided, the skin layer is a functional layer, and good comfort is provided.

The invention discloses a bionic skin structure capable of generating a natural deformation effect. The bionic skin structure comprises bionic skin, a groove is formed in the back surface of the bionic skin; and / or a hard material is arranged on the back surface of the bionic skin or inside the bionic skin, and the hardness of the hard material is higher than that of the bionic skin; and / or a soft material is arranged on the back surface of the bionic skin or inside the bionic skin, and the hardness of the soft material is lower than that of the bionic skin; and / or the back surface of the bionic skin or the interior of the bionic skin is provided with a reinforcing material, and the reinforcing material is used for improving the tear resistance of the bionic skin; and / or the back surface of the bionic skin is provided with connecting points, and the connecting points are used for connecting attachment points on bones or bionic muscles. According to the scheme, the bionic skin can effectively and controllably generate the effects of specific wrinkles, traction and the like, the deformation effect is natural, simulated and more vivid, and therefore the man-machine interaction effect can be further improved.

The robot simulation skin structure comprises a temperature control unit and an evaporation heat dissipation unit, the temperature control unit comprises a flexible base layer and a silver electrode layer, the silver electrode layer covers the flexible base layer, the flexible base layer is made of a flexible PTC material, the evaporation heat dissipation unit comprises a liquid storage layer and an opening and closing door, and the opening and closing door is made of a flexible PTC material. The opening and closing door covers the liquid storage layer, the opening and closing door is a shape memory alloy opening and closing door or a shape memory polymer opening and closing door, and heat dissipation liquid is arranged in the liquid storage layer. Therefore, according to the simulated skin structure, the temperature sensing function, the self-adaptive heating function and the evaporative heat dissipation function are integrated into a single flexible structure, the autonomous response of local heat management can be achieved without an external complex control system, and therefore an extra sensor, an extra controller and an extra complex circuit are omitted; independent work and quick response of each local area are realized, and the system structure is greatly simplified.

The invention provides a low-energy-consumption mechanical anti-icing and de-icing device and method and an aircraft skin structure, and the device comprises a passive anti-icing part which comprises an elastic interlayer, and the elastic interlayer is used for being adhered to the first side face of a skin of an aircraft; the elastic interlayer at least comprises a lubricating material capable of reducing the ice adhesion strength; the active deicing part comprises a force applying device, and the force applying device faces the second side face, away from the first side face, of the skin; wherein the aircraft is frozen to form an ice layer-elastic interlayer-skin three-layer structure under the freezing condition, the force application device applies stress load to the second side face of the skin, and the ice layer is actively induced to be broken; through deformation of the elastic interlayer, stress load is concentrated on the ice layer, critical fracture displacement needed for inducing fracture of the ice layer is passively reduced, and meanwhile, through the anti-adhesion effect of the elastic interlayer, the fractured ice layer is promoted to fall off from the elastic interlayer. Through the device provided by the invention, efficient deicing with low energy consumption, repeated use and no damage to the skin structure is realized.

The invention discloses a color-changeable silica gel skin structure. The color-changeable silica gel skin structure comprises thermochromic silica gel skin, a heating piece and a temperature sensor, the thermochromic silica gel skin is made of at least one of a thermochromic silica gel material and a silica gel skin surface coated with a thermochromic silica gel coating, and the thermochromic silica gel skin is further provided with the heating piece and the temperature sensor. According to the scheme, by arranging the thermochromic silica gel skin capable of changing color after being heated, the heating piece and the temperature sensor, the color of the bionic silica gel skin can be effectively and controllably changed, the more vivid visual effect is achieved, and therefore the interaction effect between the robot and people can be improved.

The utility model discloses an eVTOL aircraft wing skin structure which comprises an upper skin, the lower portion of the upper skin is connected with a lower skin, and the front end and the rear end of the butt joint position of the upper skin, the lower skin and a motor arm appearance area are connected with a front splicing piece and a rear splicing piece respectively. According to the structure, the product quality is good, the appearance is complex, the wing appearance area is in lap joint, the motor arm appearance area is in butt joint forming at the combined part of the wing appearance and the motor arm appearance, the defects that the two areas are sunken and the combined part is prone to generating fiber bridging are avoided, and the product quality is improved.

The invention relates to a self-adaptive skin structure suitable for a cross-airspace speed domain morphing aircraft, and belongs to the technical field of intelligent skin. The skin structure is of a multi-layer form and sequentially comprises a heat insulation protection layer, a flexible skin base body, a sensing layer and a bearing and driving layer from the outer side to the inner side. Wherein the outermost side adopts a fiber sandwich structure formed by coating aerogel with an alumina fiber reinforced alumina composite material as a heat insulation protective layer; a high-temperature-resistant carbon fiber elastic matrix composite material is used as a flexible skin matrix; a bearing layer and a driving layer on the inner side are integrally designed, and a honeycomb cell element structure driven by an integrated high-temperature shape memory alloy wire is adopted; an optical fiber sensor is embedded between the flexible skin substrate and the bearing and driving layer, the optical fiber sensor realizes direct strain measurement, and the thickness change of the skin is calculated through a strain measurement value; the method can realize self-adaptive active flexible deformation of the skin when the cross-airspace speed domain aircraft is in a hypersonic flight stage, and has important application value in the field of skin design of the cross-airspace speed domain aircraft.

The invention discloses a vascularized skin chip, a vascularized skin model and application of the vascularized skin chip and the vascularized skin model. The material of the vascularized skin chip does not contain polydimethylsiloxane; the vascularized skin chip comprises a dermal culture chip layer and an epidermal culture chip layer from bottom to top, wherein a vertically through culture cavity is formed between the dermal culture chip layer and the epidermal culture chip layer; the dermal culture chip layer is provided with a capillary channel, and the capillary channel is used for constructing a capillary in the dermal layer. According to the vascularized skin chip, dermis and epidermis can make direct contact, interaction between cells is truly simulated, the activity and functions of the cells are kept, good mechanical support is provided for the epidermis and the dermis layer, and cell growth and tissue form maturation are promoted. The microvessel channel can simulate microvessels of a corium layer and is used for simulating supply of nutrient substances and excretion of metabolic waste, a dynamic fluid environment is provided, and the skin structure and the microenvironment are restored more truly.

The invention discloses a zero-blood-permeation Pickering emulsion entrapment system and application thereof.The zero-blood-permeation Pickering emulsion entrapment system is prepared by the steps that spirulina protein isolate and chitosan are dissolved in deionized water respectively, and a spirulina protein isolate solution and a chitosan solution are prepared; the preparation method comprises the following steps: mixing and stirring a spirulina protein isolate solution and a chitosan solution to prepare a spirulina protein isolate-chitosan composite nanoparticle dispersion liquid; and adding an oil phase containing an active matter into the spirulina isolated protein-chitosan composite nanoparticle dispersion liquid, and homogenizing to prepare the stable Pickering emulsion of the spirulina isolated protein-chitosan composite nanoparticles. The penetration enhancing system is used for skin drug delivery, can accurately deliver the drug into the epidermis or corium layer, does not cross the skin barrier to enter blood circulation, and is an optimal drug delivery system for treating diseases in the skin or modifying the skin structure.

The invention discloses a composite monofilament with a skin-core structure and a preparation method, the monofilament structure comprises a core body structure and a skin layer structure, the core body structure adopts a pre-drafted polyester resin monofilament, and the skin layer structure adopts a polyamide resin material modified by nano conductive carbon black and polytetrafluoroethylene. The polyester core yarn is used as a framework of the composite monofilament to keep the monofilament to have required tensile strength, elongation, shrinkage and dimensional stability in the length direction, and the skin layer is used as a coating layer to endow the composite filament with required conductive or anti-static performance, high wear resistance and self-cleaning performance. The monofilament is used for completely or partially replacing a spiral net made of common polyester monofilaments with the same or similar wire diameter, has excellent conductive / anti-static performance and wear resistance, has self-cleaning performance, and is used for a process transmission net needing conductive or anti-static performance.

The invention provides a skin fibrosis in-vitro model as well as a construction method and application thereof, and relates to the technical field of cell biology. According to the skin fibrosis in-vitro model construction method, a full-thickness skin model with an epidermal layer and a corium layer is constructed by utilizing a cell culture chamber or a cell culture micro-fluidic chip, and the skin fibrosis in-vitro model is obtained by performing induced culture through a chemical reagent, a growth factor or mechanical stress while the corium layer is constructed. According to the construction method, the problem that an existing in-vitro model can only reflect early-stage fibrosis skin characteristics and cannot effectively simulate fibrosis skin formed under the condition of a long disease course is solved. Besides, the corium layer and the epidermal layer in the full-thickness skin structure are not separated, isolated and differentiated through a porous membrane, corium layer fibrosis can generate more direct influence on the epidermis, richer inflammatory factor expression change of the whole model is obvious, and the simulation degree of skin fibrosis diseases is higher.

The invention provides self-adjustable skin bionic hydrogel, a preparation method and application, and belongs to the technical field of biomedical materials, methyl acrylate (MA), 3-acrylamido phenylboronic acid (AAPBA) and the like are used as raw materials to prepare organogel, polyphenol drugs and antibiotics are encapsulated, double-drug-loading organogel is prepared, and the hydrogel is used for preparing the skin bionic hydrogel. The preparation method comprises the following steps: firstly, preparing a hydrogel (QL-MAB) by replacing an organic solvent with water as a medium, carrying out rapid phase separation on an MA hydrophobic fragment to form a compact outer layer similar to'epidermis', combining an AAPBA fragment with quercetin through a borate bond to construct a glucose-responsive'pore '-similar active site, and finally constructing a skin bionic hydrogel system which simulates a skin structure and can realize intelligent drug delivery. The skin bionic hydrogel provided by the invention can realize on-demand release of drugs, and can effectively promote the repair of wound surfaces infected by diabetes mellitus.

The invention relates to a preparation method of a biological membrane with a bionic cuticle'brick-slurry 'structure and a wound dressing application of the biological membrane, and belongs to the technical field of biological auxiliary materials. The preparation method comprises the following steps: dispersing prepared wool keratin microspheres in a fibroin solution, realizing a stable and firm brick-slurry structure by combining solvent volatilization with a photo-crosslinking technology, further crosslinking by utilizing metal ion coordination, and simultaneously endowing the dressing with the capabilities of effectively blocking bacterial permeation and sterilizing. The biological membrane exceeds the design of traditional layered wound dressings, and accurate reproduction of a natural skin structure is preferentially considered. The microspheres are assembled into a densely-arranged masonry structure material in a planned manner, so that the dressing has high moisture permeability, oxygen permeability and strong antibacterial barrier capacity, can promote repair of infectious wounds and burn and scald wounds, and has remarkable clinical application value.

The invention discloses a particle trap based on a shark skin structure, and relates to particle traps. A plurality of air inlet ducts and air outlet ducts are formed in the carrier, porous medium wall surfaces are arranged between the adjacent air inlet ducts and air outlet ducts, and a plurality of shark skin odontoid imitating placoid scale structures are arranged on the hole walls of the air inlet ducts. By simulating a streamline structure of shark skin, a shark skin odontoid imitating placoid scale structure is designed in the air inlet duct, and the placoid scale structure can destroy a boundary layer and delay flow separation, so that differential pressure resistance is reduced, the effect of optimizing a flow path of airflow is achieved, and exhaust back pressure is effectively reduced.

The invention provides a beautifying composition and application thereof in whitening, anti-inflammatory and anti-aging products, and belongs to the technical field of cosmetics. The beautifying composition is prepared from collagen peptide, sodium hyaluronate and ergothioneine, wherein the mass concentration ratio of the collagen peptide to the sodium hyaluronate to the ergothioneine is (75 to 85) to (3.5 to 10) to (0.4 to 3.5); the beautifying composition shows remarkable advantages in the aspects of collagen regeneration and skin improvement, the collagen content can be remarkably increased, and multi-effect collagen regeneration promotion is achieved by inhibiting collagen degrading enzyme MMP-1 and up-regulating TGF-beta1; the content of AQP3 and HA can be increased, and water locking and moisturizing of the skin are enhanced; by activating an Nrf2 pathway, the SOD2 level is improved, IL-6 and IL-1alpha are inhibited, and the antioxidant, anti-inflammatory and whitening effects are achieved; the thickness of an epidermal layer and the density of dermal fibroblasts can be remarkably improved, wrinkle resistance and repairing are effectively achieved, and the skin structure is improved.

The invention relates to the technical field of functional nutritious food, in particular to multi-layer skin nutrition powder with a whole-spectrum skin growth and repair promoting effect and a preparation method and application thereof, the core of the multi-layer skin nutrition powder is composed of a collagen peptide system (60-62%), a proteoglycan system (20-22%) and the like, collagen peptide is compounded with three sources of cattle, fish and chicken, and the multi-layer skin nutrition powder has the advantages that the multi-layer skin nutrition powder is prepared; according to the present invention, with the combination of the following components, the skin structure and activity are jointly promoted by using the synergistic effect of the functional polypeptide compound (2.5-3.5%) and the plant active component (3.5-4.5%) rich in asiaticoside and procyanidine, and the nutrition enhancers (4-5%) such as L-ascorbic acid and amino acid chelated zinc and the food-grade auxiliary materials (8-10%) such as microcrystalline cellulose are integrated in the formula, such that the various systems achieve the synergistic effect so as to achieve the effect of nourishing the skin; through the synergistic compatibility of the three-source collagen peptide, the comprehensive supplement of various types of collagen in skin tissues is realized.

The invention discloses a skin-tightening anti-wrinkle essence and a preparation process thereof, and relates to the technical field of cosmetic preparation, and the preparation process comprises the following steps: obtaining animal umbilical cord tissue, culturing, collecting cell culture supernatant after culture, carrying out low-speed centrifugation to remove cells and dead cells, and carrying out concentration, filtration and sterilization through a tangential flow membrane technology to obtain the skin-tightening anti-wrinkle essence. The animal umbilical cord extract is obtained; the preparation method comprises the following steps: mixing the animal umbilical cord extract with water, butanediol, glycerol, hydroxypropyl tetrahydropyrantriol, 1, 2-hexanediol, trehalose, p-hydroxyacetophenone, allantoin, hydrolyzed sodium hyaluronate, sodium hyaluronate, tetrahydromethylpyrimidine carboxylic acid, xanthan gum and essence, homogenizing under a stirring condition, and standing for defoaming. By constructing an active stable microenvironment and an efficient transdermal delivery system, the technical problem that the animal umbilical cord extract serving as a core component is easy to inactivate and difficult to absorb is solved, and a faster and more stable skin structure remodeling effect is realized by utilizing the synergistic effect of the animal umbilical cord extract and functional components.

The invention provides a power generation and energy storage flexible composite skin assembly, which comprises a flexible solar cell, a flexible energy storage cell and a flexible insulating substrate, and is characterized in that the flexible solar cell is arranged on the front surface of the flexible insulating substrate, and the flexible energy storage cell is arranged on the back surface of the flexible insulating substrate. The beneficial effects of the invention are that the flexible solar cell, the flexible energy storage cell, the flexible insulating substrate, the packaging layer and the management circuit are integrated in the skin structure, the advantages of light weight, flexibility, high integration and the like are realized, power supply and electric energy storage are realized, the output of the overall electrical performance of the skin assembly is improved, and the cost is reduced. The maximum power output is kept in the electrical performance output process, and the environmental adaptability and cruising ability of the unmanned aerial vehicle can be greatly improved.

The invention discloses a lamellar liquid crystal nano composition with multiple anti-aging effects and application thereof, and the lamellar liquid crystal nano composition comprises the following components in percentage by total weight of the composition: 0.1-20% of glycolipid emulsifier; 0.1%-5% of an amino acid emulsifier; 0.1%-5% of retinol and a derivative thereof; 0.01%-5% of a water-soluble active matter; 0.01% to 1% of ceramide NP; 10%-20% of grease; 30%-50% of a polyol; the total percentage is 100%. A biological surfactant, ceramide and an amino acid surfactant are compounded according to a certain proportion to form a lamellar liquid crystal structure similar to a skin structure.

The invention relates to a skin structure forming quality control system and method. Comprising a six-axis industrial robot (1), a tail end quality detection unit (2), a rotary table (4), a supporting platform (5) and a control table (6). The tail end quality detection unit (2) is used for acquiring surface image information in real time and transmitting the surface image information back to the control console (6) for defect detection, and the control console (6) is used for controlling the tail end quality detection unit (2) to move and position to a defect area according to a defect detection result. According to the invention, the error rate of operators can be effectively reduced, the skin composite material forming efficiency is greatly improved, and the economic loss of enterprises is reduced.

The utility model discloses an integrally vulcanized nonmetal expansion joint structure which comprises a skin body. The skin body comprises two inner fluorine rubber layers which are arranged in a laminated mode, and a stainless steel mesh layer is arranged between the two inner fluorine rubber layers. Outer fluorine rubber layers are compounded on the outer sides, deviating from each other, of the two fluorine rubber layers respectively, and aramid fiber cloth layers are arranged between the outer fluorine rubber layers and the inner fluorine rubber layers. The skin body of the expansion joint is of a multi-layer composite structure, the skin structure is provided with the two inner fluorine rubber layers, the two outer fluorine rubber layers, the stainless steel mesh and the aramid fiber cloth layer, the skin body is formed after the two inner fluorine rubber layers, the two outer fluorine rubber layers, the stainless steel mesh and the aramid fiber cloth layer are composited, the structural strength, the corrosion resistance and the high-temperature resistance of the expansion joint are remarkably improved under the condition that the structures of all the layers are composited, and the service life of the expansion joint is longer; and meanwhile, the mounting mode is simplified, and the mounting is convenient and stable.

The utility model provides a pressurizing calandria sandwich skin structure and an aircraft, the pressurizing calandria sandwich skin structure comprises an upper panel, a lower panel and at least one layer of pressurizing calandria limited between the upper panel and the lower panel, each layer of pressurizing calandria is formed by tightly arranging a plurality of pipe fittings with circular sections, and the pipe fittings are filled with gas with set pressure. According to the pressurizing calandria sandwich skin structure, loads are transmitted through gas, the whole structure is evenly stressed, the interior of the sandwich skin is basically hollow, the light weight requirement can be fully met, the pressurizing calandria sandwich skin is adopted to replace a traditional solid structure, the structural weight is reduced, and meanwhile the structural rigidity requirement is met.

The application discloses a flexible metal composite skin structure capable of regulating local out-of-plane deformation and belongs to the technical field of metal skin structures. The application introduces a paper-cut structure on the surface of a metal skin, regulates mechanical response by changing characteristic parameters such as a paper-cut pattern and a metal skin thickness, so that the structure has high ductility and small plastic deformation characteristics, and the structure can recover to original deformation after the expansion of a protrusion of a driving device, thereby ensuring the continuity of a wing aerodynamic shape. The application meets the basic requirements of application to a flexible skin of a deformation wing, provides a feasible selection for the fusion of a gasbag anti-icing mechanism and a deformation wing, and is expected to be widely applied in the fields of aircraft deicing, spacecraft deicing and deformation wings.

The invention discloses a tactile joint of a robot and the robot, and belongs to the technical field of robots. The tactile joint of the robot comprises a joint body and bionic skin, and the skin adhesive force can be improved through protruding structures evenly arranged on the surface of the joint body. The bionic skin is of a multi-layer bionic skin structure, the bionic skin sequentially comprises a supporting layer, a sensing layer and an epidermal layer from inside to outside, the supporting layer, the sensing layer and the epidermal layer are bonded through silicon-based elastomer materials, the durability of the skin can be effectively enhanced through the structure, and the problems of cracking, deformation and the like are effectively solved; meanwhile, the attractiveness of the tactile joint is improved, the bionic skin can deform naturally at the joint without obvious joints, the flexibility of the bionic skin can be kept under the condition that the movement range of the joint is not affected, and it is guaranteed that the robot acts coordinately and smoothly.

The invention discloses a flexible metal composite material skin structure capable of regulating and controlling local out-of-plane deformation, and belongs to the technical field of metal skin structures. The paper-cut structure is introduced to the surface of the metal skin, the mechanical response of the paper-cut structure is regulated and controlled by changing characteristic parameters such as a paper-cut pattern and the thickness of the metal skin, so that the structure has the characteristics of high ductility and small plastic deformation, and the structure can recover to original deformation along with retraction of the driving device after expanding and protruding along with the driving device; and the aerodynamic configuration continuity of the wing is ensured. Basic requirements of flexible skin applied to the deformable wing are met, a feasible choice is provided for fusion of an air bag anti-icing and deicing mechanism and the deformable wing, and the method is expected to be widely applied to the fields of aviation, spacecraft deicing, deformable wings and the like.