The invention discloses a method for preparing skin of a robot with high flexibility. The method comprises the following steps of S1, utilizing plasma equipment for etching a thermosplastic elastomermatrix material to prepare a flexible elastic matrix, wherein the repetitive unit of the flexible elastic matrix is 1-100 microns, through micro/nano processing technologies of photoetching, microfluid control and 3D printing, particles are introduced to the surface of the repetitive unit, and micro/nano patterning of the surface of a prepared flexible substrate is achieved; S2, coating the surface of the micro/nano patterned flexible substrate with a graphene or carbon nano tube solution to serve as a conductive layer; S3, coating a sensor electronic chip element with a layer of coupling agent, and implanting a pressure sensor electronic chip original element which is subjected to surface treatment into the thermosplastic elastomer matrix through an embedding method. According to the method, electronic chips can be effectively combined with the matrix material, the efficiency of the chips is achieved, and the application range of the electronic skin is expanded.