244results about How to "Good magnetic response" patented technology

The invention belongs to the nano-composite material technology field, in particular to a magnetic inorganic nano-particle/ordered mesoporous silica core-shell microsphere and a preparation method thereof. The invention first utilizes sol-gel chemical synthesis method, coats a layer of amorphous silica on the surface of a plurality of magnetic inorganic nano-particles, then utilizes self-assembly of an organic surfactant as structure-directing agent and inorganic species in the solution, coats a layer of ordered meso-structured silica/surfactant composite material on the surface of the magnetic inorganic nano-particle/ silica composite microsphere, removes the surfactant through solvent extraction, and obtains the ordered mesoporous magnetic inorganic nano-particle/silica core-shell structure composite microsphere material. The composite microsphere has high specific surface area, strong magnetic responsiveness, and wide application prospect in bioseparation and bioabsorption. The invention is simple in method, easy in obtaining raw materials, and suitable for large scale production.

A magnetic microphere of doxytaxol for preventing and treating tumor contains proportionaly magnetic Fe3O4 nanoparticles, alpha 1-acidic glucoprotein, doxytaxol and oleic acid. Its advantage is high target performance. Its preparing process is also disclosed.

The invention relates to magnetic silicon dioxide microspheres with a nuclear shell and surface anisotropic double functional groups and a preparation method thereof. The preparation method comprises the following steps of: preparing superparamagetic microspheres by a solvothermal process; preparing magnetic microspheres which are coated by silicon dioxide by a sol-gel process; preparing the magnetic silicon dioxide microspheres of which the surface has amino group by taking the magnetic silicon dioxide microspheres as seeds and by the copolycondensation of alkyl ester orthosilicate and a silane coupling agent, and drying the magnetic silicon dioxide microspheres to obtain samples; and by a PICKERING emulsion technology, stabilizing a paraffin/aqueous emulsion system with a micrometer scale by using the aminated magnetic microspheres to form single-layer close packing of the magnetic microspheres on the surface of paraffin spheres, then reacting the amino group on the surface of the magnetic microspheres which is exposed in a liquid phase with succinic anhydride to introduce carboxyl into the partial surface of the microspheres, so that the surfaces of the magnetic microspheres have the anisotropic double functional groups. The obtained magnetic microspheres with the double functional groups have the advantages that: magnetic responsiveness is high; grain size can be controlled between 200 and 800 namometers; and the density of the surface functional groups can be adjusted.

An eddy-current sensor for nondestructive testing according to the present invention includes a planar exciting coil having a pair of current lines in parallel with each other through which exciting currents flow in opposite directions to each other during the testing, for generating an alternative magnetic field applied to a subject to be nondestructively tested by the exciting currents, and at least one MR element positioned on a central axis between the pair of current lines and on the opposite side to the subject in relation to the exciting coil, for detecting a magnetic field generated newly from the subject by an eddy-current induced by the alternative magnetic field.

The invention belongs to the field of magnetic materials and relates to a magnetic core/shell/shell triple structure material with noble metal nano particles being at a double-shell interlayer and a preparation method of the material. The preparation method comprises the following steps: with Fe3O4 magnetic particles as a core, performing surface hydrolysis on the magnetic particles through hydrolyzing tetraethyl to form a layer of SiO2, then loading the noble metal nano particles with catalytic activity on the SiO2 by a coupling method, and finally coating with a ZIF-8 shell layer with regular pore channels to enable the noble metal nano particles to be positioned at the double-shell interlayer, thus obtaining the magnetic core/shell/shell triple structure material. The obtained composite material has the advantages that not only can fast separation of the material and a reaction system be realized by adding a magnetic field, but also the noble metal nano particles are positioned at the double-shell interlayer to be prevented from being lost and gathered, and simultaneously the ZIF-8 membrane layer with micropores at the outer layer also can endow the material with shape-selective and selectively-permeable functions, so that the magnetic core/shell/shell triple structure material has good potential application prospect in the fields of shape-selective adsorption and catalysis.

The invention relates to a magnetic bionic adsorbent and an application of the magnetic bionic adsorbent in treating acid wastewater containing uranium. A solvothermal method for preparing Fe3O4 by taking PSSMA (poly (4-styrene sulfonate-copolymer-maleic acid) sodium salt) as a surfactant is improved, grain sizes are uniform, and Fe3O4 magnetic nanoparticles can be synthesized on a large scale; biomolecule dopamine is polymerized in a trihydroxymethyl aminomethane buffer system and coats the surfaces of the Fe3O4 magnetic nanoparticles, and the novel magnetic bionic adsorbent with a core-shell structure is established. The magnetic bionic adsorbent has excellent hydrophilicity and larger specific surface area due to the the polydopamine structure of a shell layer, rich functional groups on the surface of the magnetic bionic adsorbent have high uranium adsorption capacity in a wider acidity range, the magnetic bionic adsorbent has higher uranium adsorption capacity and good selectivity, and uranium adsorbed on the surface of the adsorbent can be easily washed with a 0.1 mol/L (NH4)2CO3 solution and can be recycled conveniently.

The invention belongs to the technical field of advanced nanocomposites, and particularly relates to a magnetic mesoporous silica nanochain with a core-shell structure and a preparation method of thenanochain. The method comprises the following steps of firstly, coating a layer of amorphous silica on the surface of magnetic inorganic nanoparticles by using a sol-gel chemical synthesis method, andinducing oriented arrangement of the magnetic inorganic nanoparticles to form a one-dimensional core-shell structure nanochain through applying an external magnetic field; secondly, utilizing an organic surfactant as a self-assembly behavior of a structure-directing agent and an inorganic species in solution, and coating a layer of silica/surfactant composite on the surface of a magnetic inorganic nanoparticle/silica composite nanochain through an organic chambering solvent; and finally, removing the surfactant through solvent extraction in order to obtain a magnetic inorganic nanoparticle/silica core-shell structure nanochain composite with ordered mesoporous vertical divergence pore channels. The nanochain has a relatively high specific surface area, a large pore size, good magnetic responsiveness and biocompatibility, and a wide application prospect in the aspects of biological separation, adsorption, drug loading and the like.

Disclosed is a process of preparing magnetite nanoparticles, comprising the following steps: 1) preparing a ferric salt mixed system, wherein a soluble ferric salt is dissolved in glycol at ambient temperature, and then urea and polyethylene glycol are added and mixed homogeneously to obtain the trivalent iron salt mixed system, the mass ratio of glycol to the trivalent iron salt being 15:1 to 60:1, glycol to urea being 20:1 to 100:1, and glycol to polyethylene glycol being 20:1 to 100:1; 2) reacting, wherein the trivalent iron salt mixed system is transferred into a reaction autoclave, sealed and placed into a heating device to react at a temperature of 200 to 300° C. for 8 to 72 hours; and 3) washing, wherein after the reaction system is naturally cooled down to ambient temperature, the product is taken out, and washed with anhydrous ethanol and water in turn to obtain the magnetite nanoparticles. The soluble iron salt includes ferric chloride, ferric sulfate, ferric acetate and ferric nitrate. The obtained nanospheres exhibit a uniform distribution of the particle diameter with a good dispersity in water. The nanospheres have superparamagnetism, and their particle diameter can be controlled by varying the reaction time as desired.

The invention relates to a folic acid coupled targeted ferriferrous oxide/mesoporous silica/copper sulfide nano-composite particle as well as a preparation method and an application thereof. The nano-composite particle consists of Fe3O4@mSiO2 core-shell structural nanoparticles, wherein the core-shell structural nanoparticles take Fe3O4 nanoparticles as cores and mSiO2 as shells, and copper sulfide nanoparticles and folic acid cover the surfaces of the shells; the folic acid is grated on one part of the mesoporous silica (mSiO2) and the copper sulfide particles are loaded on the other part of the mesoporous silica; and polyethylene glycol is grated on the surface of the copper sulfide nanoparticles. Compared with the prior art, the nano-composite particles disclosed by the invention has a broad application prospect in the aspects of nuclear magnetic resonance imaging, drug loading and photothermal therapy; anti-cancer drugs and photothermal reagents can be transmitted to tumor parts in a targeted mode; the nano-composite particle can reduce toxic and side effects on normal tissues and cells, and meanwhile, the nano-composite particle can effectively kill cells, so that a treatment effect is further improved; and moreover, the nano-composite particle is relatively low in preparation condition demand and cost.

Adsorbent particles comprising superparamagnetic and/or low Curie Temperature transition metal-containing cores surrounded by a hydrous siliceous oxide coating can be formed by an aqueous process wherein the core is precipitated from an aqueous solution and a siliceous oxide coating is deposited thereon while complete drying of the core is avoided until after the siliceous oxide is deposited. The resulting siliceous adsorbents exhibit strong superparamagnetic and/or low Curie temperature magnetic properties with low transition metal leachability.

The invention discloses a chitosan/polyvinyl alcohol/ferroferric oxide composite magnetic particle as well as preparation and application thereof, and relates to a composite magnetic particle, which is formed by the following components in percentage by mass: 20-80% of chitosan, 10-75% of polyvinyl alcohol and the balance of ferroferric oxide. The particle diameter is 500-4000 micrometers and is controllable. The preparation method comprises the following steps: mixing a chitosan acid solution with a polyvinyl alcohol water solution; adding ferroferric oxide powder; dispersing ferroferric oxide powder in the mixed liquid to obtain a mixed liquid; adding a NaOH solution into the mixed solution; curing to ball-shaped particles; collecting the obtained ball-shaped particles through an outside magnetic field and adding the particles into ethanol; swelling and standing; soaking and washing, and drying to obtain the chitosan/polyvinyl alcohol/ferroferric oxide composite magnetic particle. As shown in experiment, the chitosan/polyvinyl alcohol/ferroferric oxide composite magnetic particle can be used in preparation of agents for removing heavy metal in water.

The invention relates to a magnetic solid acid catalyst which comprises magnetic aluminum oxide and transitional metal loaded on the magnetic aluminum oxide, wherein the weight proportion of the magnetic aluminum oxide and the transitional metal is 1.5-99:1 on the basis of transitional metal sulphate, and the transitional metal is one or more selected from IB, IIB, IVB and VIII groups; the magnetic aluminum oxide comprises Gamma-Al2O3 and magnetic particles embedded in the Gamma-Al2O3, and the weight proportion of the Gamma-Al2O3 and the magnetic particles is 1-9:1; the magnetic particles comprise SiO2 and magnetic kernels embedded in the SiO2, and the weight proportion of the SiO2 and the magnetic kernels is 0.1-1:1; the magnetic kernel is one or more selected from magnetic metals, magnetic alloys and magnetic metal oxides. The magnetic solid acid catalyst has the characteristics of large specific surface area, good magnetic property, stable physicochemical property, and the like, can be applied to processes of fluidized bed and magnetic stabilization bed and is specially suitable for integrating with a magnetic stabilization bed reactor for acid catalyzed reaction in the filed of oil processing.

The invention relates to a preparation method of a magnetic microspheres-based levofloxacin surface imprinted material. The preparation process mainly comprises three steps: preparation of magnetic microspheres; coating of the magnetic microspheres with a molecularly imprinted material; and elution of template molecules. A synthetic method provided by the invention is simple. The prepared magnetic microspheres-based surface molecularly imprinted material has specific recognition function, high adsorption capacity and rapid adsorption ability of levofloxacin and has chiral resolution function of ofloxacin, has good magnetic response and high mechanical strength, can be used as an absorption filler or a coating material, also can be used in preparation of a molecular imprinting sensor and a chip, and is of great significance for researches on specific recognition, chiral resolution and highly sensitive detection of floxacin drugs.

This invention discloses a nm magnetic microsphere and a nm magnetic immune microphere, their preparation method, (inverse micro-emulsion) its usage and its pharmaceutical composition, among which, said nm microsphere contains a macromolecular packed layer formed by chemical-cross linking with a degradable macromolecular material containing amino-group, the packed layer contains nm magnetic material, the mean size of the microspheres is 20-80nm. The nm magnetic immune microsphere with nm magnetic microsphere as the core is connected with a bioactive subject on the surface. Said nm magnetic microshpere is generated by the reaction of nm magnetic material, macromolecular material and the crosslinker in the inverse micro-emulsion.

The invention discloses a pH-responsive magnetic metal organic framework composite nano-material and its preparation method and use. The pH-responsive magnetic metal organic framework composite nano-material comprises Fe3O4 nanoparticles, polymer layers coating the surfaces of the Fe3O4 nanoparticles and a metal organic framework growing on the polymer layers. The polymer layer comprises a first polymer chelated with metal ions or comprises the first polymer chelated with metal ions and a hydrophilic second polymer. The metal organic framework is formed from Fe<3+> and a phenylboronic acid derivative containing at least one carboxyl group or at least two boronic acid groups through a coordination bond. The composite nano-material provided by the invention has good magnetic response performances and can realize reversible and highly selective capture and release of glycoprotein in different pH environments, and the pH environment is relatively mild so that the influence on the glycoprotein activity is avoided.