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1667results about How to "Stable physical and chemical properties" patented technology

Microsphere type embolic agent and preparation technology thereof

The invention provides a microsphere embolic agent, which is an elastic microsphere formed by the crosslink polymer of the functionalized macromolecules with the biocompatibility, and the particle size of the microsphere ranges from 1 Mum to 1500 Mum. The preparing technology includes the steps as follows: in a covalent link, linking a crosslinkable micromolecules with an acrylic acid structure on the polyvinyl alcohol, polyethylene glycol or polysaccharide macromolecules, forming the functionalized macromolecules; after that, the functionalized macromolecules and the monomer of the 2- acrylamide-2-methyl propanesulfonic acid undertakes opposite suspension polymerization, obtaining the crosslink polymeric microsphere embolic agent. The embolic agent has comparatively large retractility and elasticity, whose particle size is controllable and has perfect dispersiveness; moreover, the raw material is non-toxic and at the same time has good biocompatibility and stability. The preparing technology is a real chemosynthesis technology, whose material and preparing process does not produce any virus pollution, according with various requirements of the international embolic agent, which can replace various import and domestic expensive embolic agent products and is extensively applicable to various surgeries in the interventional radiology field.
Owner:SUZHOU HENGRUI CALLISYN BIOLOGICAL MEDICINE TECH CO LTD

Ultrahigh-strength grouting material based on iron tailing sand and cement and preparation method of grouting material

The invention relates to an ultrahigh-strength grouting material based on iron tailing sand and cement and a preparation method of the grouting material. The ultrahigh-strength grouting material is composed of the following components in proportion by weight: 30%-45% of cement, 45%-55% of iron tailing sand, 6%-15% of multielement mineral admixtures, 0.35%-1% of water reducing agent, 0.1%-1% of plastic retaining agent, 0.01%-0.1% of plastic expanding agent, and 2%-6% of shrinkage-compensating expanding agent. The preparation method comprises the steps of uniformly mixing all the components and then uniformly stirring the mixed components in water, wherein the ratio of the water to the materials is 0.09-0.11. The grouting material is good in flowability, is good in stability in a plastic stage, is free from shrinkage in the whole course from the plastic stage to a later hardening stage, and is ultrahigh in early strength, final strength and elasticity modulus, the 1d compressive strength of the material reaches up to 50MPa, the 28d compressive strength of the material can exceed 110MPa, and the 28d elasticity modulus of the material exceeds 45GPa, and therefore, the ultrahigh-strength grouting material is suitable for grouting of various important parts or areas with requirements on high strength and high modulus.
Owner:WUHAN UNIV OF TECH

Method for extracting high-purity squalene by taking olive oil as raw material

The invention relates to a method for extracting high-purity squalene by taking olive oil as a raw material. A technological route formed by adopting a secondary molecular distillation and silica gel column chromatography is as follows: an olive oil unsaponifiable substance is taken, squalene is separated and purified by using two stages of molecular distillation, primary molecular distillation is carried out under the conditions of the evaporation surface temperature of 100 to 200 DEG C, the systemic pressure of 0.001 to 0.01mbar and the scraping film rotor speed of 150 to 300rpm, and secondary molecular distillation is carried out to the obtained distillate; the secondary molecular distillation is carried out under the conditions of the evaporation surface temperature of 150 to 300 DEG C, the systemic pressure of 0.001 to 0.01mbar and the scraping film rotor speed of 200 to 350rpm, and the obtained distillate is a squalene crude product; ethyl acetate-normal hexane with different concentrations is used as a mobile phase to carry out gradient elution, the obtained eluent is collected according to time and a solvent is evaporated, the same fractions are merged through chromatographic detection, and the high-purity squalene can be obtained, wherein the content of the raw material olive oil of the squalene is enhanced from 3.6% to about 98%; and especially, by considering the requirement of industrialized production to select an extraction condition especially, the large-scale production of the squalene taking the olive oil as the raw material can be realized.
Owner:JIANGSU ZODIAC MARINE BIOTECH

Ink-jet dry granular decorative ceramic tile and manufacturing method thereof

The invention relates to the technical field of ceramic tiles, in particular to an ink-jet dry granular decorative ceramic tile and a manufacturing method thereof. The manufacturing method includes the following steps: A. bottom glaze decoration; B. pattern decoration; C. drying for the first time; D. dry granular decoration; E. spraying a protective glaze; and F. calcining to obtain the product.The method for preparing the dry granular decorative ceramic tile has the advantages of simple operation steps, convenient control, simplified process flow, improved production efficiency, reduced production difficulty and production cost, so that the method is suitable for industrial large-scale production; by spraying with dry granular ink, spray printing can be carried out on a designated position on the surface of a blank body, so as to enable a spray printed texture to be accurately correspond to a pattern decorative texture, and thus the distribution uniformity and adhesion of dry granules on the surface of the blank body are improved, and the prepared ceramic tile product has clear and distinct patterns, low glaze gloss, good anti-skid effect, obvious dry granular feeling, strong stereoscopic impression, rich colors, stable physicochemical properties and wide temperature adaptation range.
Owner:JIANGXI HEMEI CERAMICS +3

Magnetic carrier iron ordered mesoporous carbon, preparation method and application thereof

The invention discloses a magnetic carrier iron ordered mesoporous carbon. The ordered mesoporous carbon is taken as a carrier, the carrier is prepared by a hard template method, and magnetic nanoparticles are loaded onto the carrier by a nano-joint casting method; the magnetic nanoparticles mainly consist of zero-valent iron and oxide of iron, wherein the proportion of the iron element is taken as 1-1.5m mol of each gram of a mesoporous silicon template, and the pore diameter distribution of the mesoporous carbon is mainly concentrated nearby 5nm and 3.8nm. A perpetration method of the magnetic carrier iron ordered mesoporous carbon provided by the invention comprises the following steps of: dissolving iron source materials and cane sugar in sulfuric acid, dipping the mesoporous silicon template, and adopting two-section type heat treatment; secondly, dipping by cane sugar-containing sulfuric acid solution, and adopting two-section type heat treatment; and finally carrying out constant-temperature high-temperature carbonization so as to obtain the silicon template in a demoulding way by hot NaOH solution, and drying to obtain the magnetic carrier iron ordered mesoporous carbon. The magnetic carrier iron ordered mesoporous carbon disclosed by the invention has the characteristics of being large in specific surface area and pore volume, wide in application range, stable in physicochemical property and the like, and the heavy metal hexavalent chromium ions in water body can be removed.
Owner:HUNAN UNIV

Novel passive target skin whitening efficacy nanoemulsion for night and daylight and method of preparing the same

The invention relates to a novel passive targeting nano emulsion with skin whitening effect and a preparation method thereof. The invention uses a novel passive targeting transdermal delivery dosing system TDDS-nano emulsion as a carrier of a function component for whitening or lighting the skin, uses different physical and chemical properties, action mechanism and actual effect of each skin whitening function component, especially the action advantages of certain novel skin whitening function components, and provides skin whitening effect nano emulsion systems with two joint applications in morning and evening matched with each other. The two joint applied nano emulsion systems not only have minimum spherical grains, extremely even distribution of nano-scale grains, remarkable passive targeting function, good transdermal absorption and strong penetrability, but also have extremely even, exquisite, smooth and glossy texture of the nano emulsion, is quite comfortable after coating on the face or the skin, has no stimulus and good stability; and the nano is light yellow, beautiful in appearance, bright and transparent, clear and crystalline, has light opalescence, and is adhesive but not sticky, thick but not heavy, oily but not greasy.
Owner:董萍 +1

Preparation of hyaluronic-acid-based double-targeting nano-composite medicament and application of double-targeting nano-composite medicament

The invention relates to a hyaluronic-acid-based double-targeting nano-composite medicament and a preparation method thereof. Hydrophobic group ursodeoxycholic acid is included in a hyaluronic acid nano-polymer structure and can form an amphipathic polymer and automatically generate micelles in an aqueous solution, and polyethylene glycol can be introduced into the micelles to improve the dispersity and stability of a composite. An anti-tumor medicament can enter a nano-carrier through electrostatic adsorption or physical inclusion to generate a nano-medicament composite, wherein the nano-medicament composite is selectively concentrated in a tumor cell under an active targeting effect of hyaluronic acid and a surface CD44 receptor of a tumor cell, and promotes a tumor tissue to absorb the nano medicament-carrying composite by using a passive osmotic accumulation effect (EPR) at the same time. After an anti-tumor medicament is wrapped by a modified hyaluronic acid polymer, the anti-tumor medicament has the advantages of improving the bioavailability of the medicament, improving the targeting property, reducing the toxic and side effects, prolonging the half-life period of the medicament, being stably stored and the like, so that the tumor targeting therapy efficiency is improved in many ways.
Owner:XIAMEN UNIV

Circulation tumor cell automatic separation and purification micro-fluidic chip and separation and purification method thereof

ActiveCN107402295AHigh purityAvoid spurious resultsMaterial analysisPurification methodsMicro column
The invention discloses a circulation tumor cell automatic separation and purification micro-fluidic chip and a separation and purification method thereof. The circulation tumor cell automatic separation and purification micro-fluidic chip comprises a separation and purification chamber, a diversion column and micro columns, wherein a sample inlet, a first outlet from which target cells flow out, and a plurality of second outlets from which non-target cells flow out are formed in the separation and purification chamber; the separation and purification chamber is internally provided with two micro column arrays; each micro column array consists of a plurality of micro column rows; each micro column row comprises a plurality of micro columns; a gap is formed between every two adjacent micro columns of one micro column row; the gap forms a non-target cell channel; a gap is formed between two micro column arrays; the gap forms a target cell channel from which the target cells pass; the width of the target cell channel is greater than that of the non-target cell channel; an acute angle is formed between the micro column rows and the target cell channel; and the acute angle faces to the sample inlet. The circulation tumor cell automatic separation and purification micro-fluidic chip is high in separation and purification degree.
Owner:SUREXAM BIO TECH

Preparation technology for microspheric embolization agent

The invention relates to a preparation technology for a microspheric embolization agent. The preparation technology is used for preparing elastic microspheres cross-linked and polymerized by functionalized macromolecules with biocompatibility, wherein the grain range of the microspheres is 1-1500mu m. The preparation technology comprises the following steps that: a cross-linkable micromolecule with a crylic acid structure is connected on a polyvinyl alcohol, polyethylene glycol or polyose macromolecule in form of a covalent bond to form a functionalized macromolecule; and reversed phase suspension polymerization is conducted to the functionalized macromolecule and a 2-acrylamide-2-methylpropanesulfonic acid monomer to prepare cross-linked and polymerized microspheric embolization agent. The embolization agent has the advantages that the flexibility and the elasticity are high, the grain is even and is controllable, the dispersity is good, the raw materials are nontoxic and the biocompatibility and the stability are good. The preparation technology is a pure chemical synthesis technology, no virus pollution is caused to the raw materials and the preparation process, the requirements on international embolization agents are satisfied, and the embolization agent can substitute for all kinds of imported or domestic expensive embolization agent products and can be widely used in surgeries in the field of interventional therapy.
Owner:SUZHOU HENGRUI CALLISYN BIOLOGICAL MEDICINE TECH CO LTD

Compound cesium fluoborate, nonlinear optical crystal with cesium fluoborate, methods for preparing compound cesium fluoborate and nonlinear optical crystal and application of compound cesium fluoborate and nonlinear optical crystal

The invention provides a compound cesium fluoborate, a nonlinear optical crystal with the cesium fluoborate, methods for preparing the compound cesium fluoborate and the nonlinear optical crystal and application of the compound cesium fluoborate and the nonlinear optical crystal. A chemical formula of the compound is CsB<4>O<6>F, the molecular weight of the compound is 291.15, and the compound is of a crystal structure and is prepared by the aid of solid-phase synthesis processes or vacuum packaging processes. A chemical formula of the nonlinear optical crystal is CsB<4>O<6>F, the molecular weight of the nonlinear optical crystal is 291.15, the nonlinear optical crystal belongs to orthorhombic crystal systems, space groups of the nonlinear optical crystal are Pna2<1>, crystal cell parameters of the nonlinear optical crystal include that an a is equal to 7.9241 , a b is equal to 11.3996 , a c is equal to 6.6638 and an alpha, a beta and a gamma are equal to 90 degrees, and the unit cell volumes of the nonlinear optical crystal are 601.95 <3>. Frequency doubling effects of the nonlinear optical crystal is approximately two times frequency doubling effects of KH<2>PO<4> [KDP (potassium dihydrogen phosphate)], and ultrasonic absorption edges of the nonlinear optical crystal are shorter than 190 nm. The nonlinear optical crystal is grown from the CsB<4>O<6>F by the aid of melt processes, high-temperature solution processes, vacuum packaging processes, hydrothermal processes or room-temperature solution processes. The compound cesium fluoborate, the nonlinear optical crystal, the methods and the application have the advantages that the nonlinear optical crystal is free of deliquescence in air, is good in chemical stability and can be applied to all-solid-state laser devices as an ultraviolet nonlinear optical crystal or deep ultraviolet nonlinear optical crystal.
Owner:XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI

Process for preparing alumina-based continuous fiber with sol-gel method

InactiveCN101723682ADense sectionHigh strengthFiberCarbon number
The invention discloses a process for preparing alumina-based continuous fiber with a sol-gel method. The process comprises the following steps of: adding aluminium nitrate and one or a plurality of kinds of carboxylic acids with the carbon number of 2 to 24 to distilled water; ensuring the mixture to react in the condition of continuous stirring under a certain temperature to obtain transparent carboxylate aluminium gel; adding a certain amount of solvent to the carboxylate aluminium gel, and adding a certain amount of silicon-contained additives and superpolymer spinning additives to obtain an alumina-based fiber precursor solution; concentrating the solution to obtain spinnable alumina-based fiber precursor sol; placing the concentrated sol to a liquid storage tank with a spray head, and spinning by adopting a dry method or a wet method to obtain alumina-based continuous fiber protofilament containing organic matters; and drying and sintering the protofilament to obtain the alumina-based continuous fiber. The alumina-based continuous fiber obtained by adopting the invention can be used for reinforcement of composite materials so as to further enhance the strength and toughness of the materials and improve the heat resistance of the materials, and is widely applied in the fields of aerospace, automobiles, and the like.
Owner:XI AN JIAOTONG UNIV

Preparation method of rare earth element modified and aldehyde removed resin and application of rare earth element modified and aldehyde removed resin in ethylene glycol refining

The invention relates to a preparation method of rare earth element modified and aldehyde removed resin and an application of the rare earth element modified and aldehyde removed resin in ethylene glycol refining. According to the preparation method, styrene is taken as a monomer, divinylbenzene is taken as a crosslinking agent, benzoyl peroxide is taken as an initiator, polyvinyl alcohol is taken as a suspending agent, water is taken as a reaction medium, and the components react in a suspension polymerization manner at the temperature of 85-95 DEG C; a polymer obtained after reaction is dissolved in dichloroethane for swelling, sulfuric acid is added for a sulfonation reaction, and cation exchange resin is obtained; and a nitric acid solution of the rare earth element is added into the cation exchange resin, and the rare earth element is chemically bonded to the resin to obtain the spherical modified and aldehyde removed resin. A fixed bed reactor is filled with the aldehyde removed resin, ethylene glycol is refined at the temperature of 60-70 DEG C, the density of a resin packing layer heap is 400-600 kg / m<3>, the reaction pressure is 0.4 MPa, under the catalytic action of the modified and aldehyde removed resin, impurity aldehyde and ethylene glycol have a condensation polymerization reaction and produce a product that does not influence an ethylene glycol product, and obtained ethylene glycol has high purity.
Owner:JIANGSU SUQING WATER TREATMENT ENG GROUP +1
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