18results about How to "Stable source" patented technology

The application relates to a YAG / Yb:YAG / YAG composite laser transparent ceramic and a preparation method thereof. The Yb:YAG water-based ceramic ink comprises mixed powder composed of Al2O3 powder, Y2O3 powder and Yb2O3 powder, the solid content is 20-25 vol%, the mole ratio of Al2O3, Y2O3 and Yb2O3 is 5:3-x:x, and 0 < x <= 0.3; the dispersant content is 0.2-0.8% of the mass of the mixed powder; the pH control agent is used in an amount controlled to adjust the pH of the Yb:YAG water-based ceramic ink to be between 10-11.5 and the pH of the ink is greater than or equal to 9.5 within 24 hours under the conditions of sealing and 20-25 DEG C; the humectant content is 5-20% of the total volume of the Yb:YAG water-based ceramic ink; the binder content is 0.1-0.5% of the mass of the mixed powder; and the sintering aid content is 0.1-0.5% of the mass of the mixed powder.

The present application relates to the technical field of metal material heat treatment, in particular to a heat treatment furnace device and method capable of controlling temperature and cooling speed, wherein the furnace body is internally constituted as a hearth, the output end of the air supply system is located at the lower region of the hearth through the furnace body; the flow equalizing system is arranged at the lower region of the hearth and is in communication with the output end of the air supply system; the workpiece is placed on the flow equalizing system; the circulation and exhaust system is arranged at the upper region of the hearth and is in communication with the interior of the hearth, the temperature monitoring system is arranged on the circulation and exhaust system and is directly above the workpiece; the control system is electrically connected with the air supply system, the circulation and exhaust system and the temperature monitoring system. The present application effectively solves the problems of insufficient cooling speed and poor cooling uniformity in the prior art.

The present application relates to adsorption separation of bisphenol A and 2,4-bisphenol A adsorbent and its adsorption separation process; the adsorbent is a high-silicon Y molecular sieve containing rare earth, the molar ratio of the contained silicon oxide and aluminum oxide is 2.5:1-15:1, the contained rare earth metal is one or a combination of multiple of lanthanum, cerium, scandium and yttrium, the content of rare earth metal is 10:1-1000:1 in terms of the molar ratio of silicon and rare earth metal, and the rare earth metal exists in the form of metal ions. The adsorption separation process is to contact the mixture containing bisphenol A, 2,4-bisphenol A, triphenol and chroman in the crystallization mother liquor with the adsorbent in the adsorption separation reactor to carry out adsorption separation, and the obtained bisphenol A and 2,4-bisphenol A after adsorption separation enter the isomerization reaction unit; the obtained triphenol and chroman after adsorption separation enter the cracking reaction unit. Phenol is used as the eluent, has strong affinity with the adsorbent, and the elution efficiency reaches more than 95%.

The invention discloses a method for extracting prenuclide and preparing medical alpha isotope on a large scale based on monazite discharged waste slag. According to the method, high-value conversion of radioactive waste is realized by comprehensively utilizing the monazite waste slag. The alpha isotope is used as a core raw material for extracting preposed nuclide, so that the environmental harm of radioactive waste residues is reduced, waste is turned into wealth, and a stable raw material source is provided for preparing the medical alpha isotope. A complete technical chain for extracting the medical alpha isotope 225Ac / 212Pb from the monazite waste slag containing 226Ra and 228Ra is constructed, and efficient output of high-value nuclides is achieved. 226Ra and 228Ra in the discharged waste slag are obtained through a step-by-step extraction process flow of a coarse radium product and a fine radium product, a radium target of an ECANS device is manufactured, and hot medical alpha isotopes such as 225Ac, 212Pb and the like can be prepared on a large scale by utilizing a photo-nuclear reaction. According to the preparation mode, the utilization rate of the discharged waste slag is increased, and the requirement of radioactive diagnosis and treatment on the medical alpha isotope can be met.

This invention belongs to the field of coating technology and provides a wear-resistant coating for drone shells and its preparation method. The raw materials of the coating include: hydrogenated bisphenol A epoxy resin, vinyl-terminated fluorinated polybutadiene resin, core-shell powder, aluminum borate nanofibers, polyetherimide micro powder, wear-resistant additives, silane coupling agent KH-792, light stabilizer, leveling agent and environmentally friendly solvent. The preparation method includes: (1) mixing hydrogenated bisphenol A epoxy resin and vinyl-terminated fluorinated polybutadiene resin to form a resin matrix; (2) first adding core-shell powder and aluminum borate nanofibers to the resin matrix for dispersion; after cooling to 25-30℃, adding other raw materials, stirring and defoaming to obtain the finished product. This coating has high wear resistance, wind and sand erosion resistance, low temperature crack resistance, microcrack self-repair, strong UV aging resistance and high adhesion, which can significantly improve the long-term service stability and service life of drone shells in complex and harsh environments such as high altitude, wind and sand, high and low temperature alternation, and strong ultraviolet radiation.

The present application relates to the technical field of immunological detection, in particular to hepatitis B PreS1 antigen and its preparation method and application. The present application first selects an active PreS1 polypeptide sequence, which is coupled to a hepatitis B surface antigen HBsAg molecule through a crosslinking agent to obtain a hepatitis B PreS1 antigen having both hepatitis B surface antigen activity and PreS1 antigen activity, which can be used as a calibrator and positive control in a hepatitis B PreS1 antigen detection kit. The kit uses anti-PreS1 antibody as coating and anti-HBsAg antibody as enzyme label. The artificial coupled hepatitis B PreS1 antigen prepared by the present application can effectively replace the currently used PreS1 real positive sample on the market, has no biological safety risk, stable source, and various indexes such as reactivity, vehicle stability and thermal stability, which are all better than those of the real positive sample, and has high innovation and applicability.

This invention provides a nanobody targeting carp herpesvirus type II and its application. The amino acid sequence of the nanobody is shown in SEQ ID NO. 1-6. The method includes immunizing alpacas with inactivated carp herpesvirus type II, collecting peripheral blood from the immunized alpacas and separating lymphocytes, and extracting total RNA; synthesizing cDNA by reverse transcription, and amplifying the gene fragment encoding the nanobody; ligating it into the pComb3xss vector, and then transforming it into competent cells to construct a nanobody phage display library; enriching and panning the inactivated virus as a coating antigen to obtain specifically binding phage particles; transforming the selected positive clones into host bacteria for induced expression; and obtaining the anti-carp herpesvirus type II nanobody after separation and purification. This invention aims to provide a carp herpesvirus type II nanobody that is low in expression cost and difficulty, has a stable source, can effectively bind to carp herpesvirus type II, and specifically achieves immunoassay of carp herpesvirus type II.

The invention relates to the technical field of medical health care products, in particular to an anticancer composition containing phellinus igniarius extract and total ginsenoside and application of the anticancer composition. The anticancer composition comprises a phellinus igniarius extract and total saponins of ginseng. The mass ratio of the phellinus igniarius extract to the total ginsenoside is 1: (0.5-2); the phellinus igniarius extract is obtained by taking artificially cultivated phellinus igniarius as a raw material through ultrasonic-assisted extraction and reflux extraction in stages; the extraction solvent is selected from water or an ethanol water solution with the ethanol concentration not exceeding 40%. The anticancer composition provided by the invention has remarkable in-vitro anticancer activity and low toxicity to normal cells.

The application provides a compound omeprazole dry suspension and a preparation method thereof, and relates to the technical field of pharmaceutical preparations.The compound omeprazole dry suspension comprises the following raw materials: omeprazole, sodium bicarbonate, magnesium silico-aluminate, hard stearic acid modified hydrotalcite, low acyl gellan gum, hydroxypropyl methyl cellulose and trehalose.The application provides a compound omeprazole dry suspension and a preparation method thereof, and the compound omeprazole dry suspension with specific particle size is prepared through specific proportioning of auxiliary materials and a specific preparation process, and the stability and solubility are significantly improved.

The invention relates to the field of medicinal chemistry, and particularly discloses a novel TLR8 agonist intermediate as well as a preparation method and application thereof, which are suitable for process development of 4, 6-diaminopyridino [3, 2-d] pyrimidine TLR8 agonists. According to the preparation method, tert-butyl is adopted to replace 2, 4-dimethoxybenzyl to serve as an amino protecting group, so that the crystallization property of the intermediate is remarkably improved, column chromatography is avoided, the cost is reduced, and the process stability is improved. The preparation method of the TLR8 agonist intermediate comprises the steps of reduction, acylating chlorination, coupling, amination and the like, has the advantages of being easy and convenient to operate, high in yield, environmentally friendly and the like, and is particularly suitable for industrial production.

This invention discloses a low-serum MDCC-MSB1 (MSB1) suspension culture medium and an inactivated chicken infectious anemia virus (TIV) vaccine. The culture medium comprises amino acids, carbon source, additives, vitamins, inorganic salts, buffer salts, and water, and further contains newborn calf serum (NBCS). Using this medium, low-cost, high-density suspension culture of MSB1 cells can be achieved, significantly improving cell culture stability. After 30 consecutive passages at a 1% volume ratio of NBCS, the viability of MSB1 cells remains above 94%, with uniform cell morphology and a clumping rate of <3%, making it suitable for large-scale bioreactor production. Furthermore, when applied to the preparation of an inactivated chicken infectious anemia virus vaccine, it can comprehensively improve virus propagation efficiency, increasing virus production efficiency by more than 25%, with a virus titer of not less than 1.0 × 10⁻⁶. 8.0 TCID 50 / ml, ensuring stable quality in large-scale production.

This invention discloses a traditional Chinese medicine composition for atopic dermatitis and its application. The composition is made from the following raw materials in parts by weight: 10-20 parts of dried plum, 5-15 parts of licorice root, 10-20 parts of Imperata cylindrica root, 5-15 parts of Smilax glabra rhizome, 5-15 parts of Coix seed, 5-15 parts of Angelica dahurica root, 3-9 parts of peppermint, 3-10 parts of Astragalus membranaceus root, 5-15 parts of dried tangerine peel, and 5-15 parts of Siraitia grosvenorii fruit. The composition can be prepared by soaking in water, decocting, and filtering to obtain a decoction, or further processed into granules, pills, tablets, capsules, or oral liquids for oral administration. Experimental results show that the composition of this invention can alleviate skin tissue damage in mice with DNFB-induced atopic dermatitis, reduce the area of ​​pathological skin tissue damage, and decrease the abnormal increase in mast cells. The raw materials of this invention are readily available, easy to prepare, and suitable for oral use, and can be used to prepare drugs for the treatment or adjuvant treatment of atopic dermatitis.

This invention relates to the field of feed resource development technology, specifically to a solid-state fermentation process for soy sauce residue. Through the synergistic effect of desalination pretreatment and mixed-culture solid-state fermentation, the nutritional quality of the soy sauce residue is significantly improved. This invention also provides the application of solid-state fermented soy sauce residue in broiler diets. The beneficial effects of this invention are: fermented soy sauce residue can be directly used as a protein feed ingredient to partially replace soybean meal, with a stable source and low cost. This not only reduces breeding costs and dependence on imported soybean meal but also realizes the resource utilization of soy sauce residue, conforming to the concepts of circular economy and sustainable development in the feed industry.

This invention provides a feed enhancer specifically for low-salinity aquaculture of redclaw crayfish and its application. It belongs to the field of feed additive technology. This feed enhancer for low-salinity aquaculture of redclaw crayfish combines plant polysaccharides and probiotics in a synergistic manner, effectively leveraging the efficacy of both polysaccharides and probiotics. The synergistic effect significantly improves the redclaw crayfish's tolerance to low-salinity environments. Compared to traditional freshwater feed aquaculture of redclaw crayfish, it solves the problems of slow growth and high mortality rates, while also increasing yield, reducing the feed conversion ratio, and maximizing aquaculture efficiency. This provides technical support for the development of redclaw crayfish aquaculture in low-salinity areas of Guangxi and also enriches the varieties of marine aquaculture.

This invention relates to a concrete paving brick made from oily sludge pyrolysis residue. It is prepared by mixing 86%–90% standard concrete and 10%–14% oily sludge pyrolysis residue by weight. Silicate cement, fine aggregate, and water are added to a mixer according to the standard concrete weight ratio. After the mortar has fully coated the inner wall of the mixer, it is poured out. The following steps are taken: Fine aggregate, cement, coarse aggregate, fine aggregate, and water are weighed according to a weight ratio of 16:51:25:8. The coarse aggregate, fine aggregate, and residue are added first and mixed. Cement is then added and mixed again. Half the water and water-reducing agent are added and mixed. The water-reducing agent dosage is 0.7% of the unit cement weight. Finally, the remaining water is added. The mixture is then molded and cured to obtain the oily sludge pyrolysis residue concrete paving brick. This invention achieves high-value utilization of oily sludge pyrolysis residue and reduces carbon emissions from concrete production.

The application discloses high-elasticity polyoxamide as well as a preparation method and application thereof, wherein the high-elasticity polyoxamide adopts polyether chains to provide a'soft segment', oxamide structures and six-membered rigid rings to provide a 'hard segment', forms a linear structure with soft and hard phase embedding, and gives the polyoxamide high elasticity; specifically, the high-elasticity polyoxamide contains polyether chain structure units and oxamide structure units shown in formula (I) in a molecular structure: wherein R' is a group containing a six-membered rigid ring. The fiber prepared by using the high-elasticity polyoxamide has high elongation at break, high breaking strength, high 200% stress and excellent elastic recovery rate.

The application provides a preparation method, product and application of lithium sulfide, and belongs to the technical field of inorganic compound synthesis. The lithium sulfide with high product purity and low carbon content is obtained through four steps of lithium source pretreatment, lithium sulfite intermediate synthesis, lithium sulfite reduction and product post-treatment by using anhydrous lithium hydroxide or lithium oxide as a lithium source, sulfur dioxide as an acidifying agent and hydrogen or methane as a reducing gas, and can be directly applied to high-end fields such as full solid-state batteries and lithium-sulfur batteries, and has important significance and broad industrial application prospects for breaking through the industrialization bottleneck of full solid-state batteries.

The invention provides a hematoxylon hairy root genetic transformation system taking seeds as receptors, and belongs to the technical field of biology. The invention provides a hematoxylon seed-mediated genetic transformation method. The hematoxylon seed-mediated genetic transformation method comprises the following steps: stripping seed coats of hematoxylon seeds, and performing puncture treatment; mixing an infection solution containing a target gene with the hematoxylon seeds subjected to puncture treatment for infection; and planting the infected seeds to obtain the transgenic hematoxylon. The invention screens and verifies the unique advantages of the seeds as the hematoxylon genetic transformation receptor, establishes a hematoxylon genetic transformation system directly using the complete seeds as the receptor for the first time, and successfully bypasses the key bottleneck of the traditional technology. According to the genetic transformation method, the genetic transformation rate of hematoxylon is remarkably increased, and the genetic transformation rate is 15%; and the genetic transformation rate is stable, and the method has the advantages of high efficiency and repeatability.