600 results about "Aging effect" patented technology

The invention provides a repairing and anti-aging composition specially researched for dry sensitive skin and application of the repairing and anti-aging composition, and belongs to the technical field of cosmetics. According to the anti-aging composition disclosed by the invention, inositol, ceramide-NP, phytosphingosine, a golden camellia extract, a waxberry bark extract and a fructus cnidii extract are selected according to a specific mass ratio, and the six components are combined for use, so that a strong anti-aging network can be formed, and a plurality of aspects act together, so that the anti-aging composition has a good anti-aging effect. The permeation promoting, repairing, moisturizing, anti-aging and soothing effects of the anti-aging composition are improved.

The invention provides a technical method for improving the anti-aging effect of eurotium cristatum tea compound fermentation liquor, and belongs to the technical field of microorganisms, the Latin name of eurotium cristatum is Eurotium cristatum, the eurotium cristatum is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC M 2024643. According to the method, the yeast seed solution is inoculated into the tea-sea buckthorn leaf culture solution fermented by the eurotium cristatum, so that the content of anti-aging active components such as procyanidine B2, quercitrin, cyanidin-3-glucoside, nicotinic acid, naringenin and rutin in the fermentation culture solution can be remarkably increased through co-fermentation, and the elastase inhibition rate can be remarkably increased; the anti-aging effect of a component system of the fermentation culture solution is enhanced. The prepared tea-hippophae rhamnoides leaf compound fermentation liquor is suitable for development of anti-aging cosmetics and has a wide market prospect.

The invention provides a preparation method of medicinal liquor and application of the medicinal liquor in preparation of antioxidant and anti-aging products, and relates to the technical field of medicinal preparations. The preparation method comprises the following steps: (1) crushing; (2) extracting; (3) standing and separating; and (4) freezing and filtering to obtain the medicinal liquor. The medicinal liquor is obtained by extracting the traditional Chinese medicine components through the steps of crushing in batches, mixing and extracting, standing, freezing and separating the supernate and the suspension in different separation modes, and the medicinal liquor can better improve the space exploration capability of a mouse aged due to D-galactose, can reduce malondialdehyde MDA, and can improve the immunity of the mouse. The activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) is improved, and the obvious anti-oxidation and anti-aging effects are achieved.

The invention relates to a barrier repair composition for activating cell energy and application thereof, the composition comprises the following components: nicotinamide, a wheat germ extract, oat beta-glucan and a golden camellia flower extract, the four components synergistically form a full-link barrier repair system of energy supply (nicotinamide)-autophagy cleaning (wheat germ extract)-structure strengthening (beta-glucan)-oxidation defense (camellia nitidissima extract), the limitation that a traditional skin care product singly supplements lipid or resists oxidation is broken through, lipid dynamic balance is rebuilt from the root of cell metabolism, and the skin care product has the advantages that the skin care effect is good; and certain skin smoothing and anti-aging effects are achieved.

The invention relates to a preparation method and application of an artificially synthesized exosome with an anti-aging effect, and belongs to the technical field of cosmetics and biology. The artificially synthesized exosome is prepared from hydrogenated lecithin, phytosphingosine, cholesterol, ceramide, squalane, sodium stearoyl glutamate, a surface modification structure, polyol, an active component and water. The preparation method comprises the steps of preparation of an alcohol phase, preparation of a water phase, preparation of a mixed solution and high-pressure homogenization treatment. The artificially synthesized exosome prepared by the preparation method provided by the invention is good in stability and high in anti-aging activity.

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.

The invention belongs to the technical field of cosmetics, and discloses a composition with tightening and anti-wrinkle effects as well as a preparation method and application thereof. The composition disclosed by the invention comprises the following components: a radix pseudostellariae extract and hydrolyzed ginsenoside. The radix pseudostellariae extract in the composition achieves the effects of tightening and resisting wrinkles by promoting generation of collagen and elastin, the hydrolyzed ginsenoside mainly has the effects of resisting oxidation, inhibiting expression of matrix metalloproteinase and preventing collagen degradation, and after the radix pseudostellariae extract and the hydrolyzed ginsenoside are combined, the composition has a better effect of inhibiting the activity of the matrix metalloproteinase, so that the effect of resisting wrinkles is achieved. The traditional Chinese medicine composition has the effects of promoting the generation of collagen and elastin, and has a synergistic effect, so that the traditional Chinese medicine composition has an excellent anti-aging effect.

The invention relates to the technical field of gel materials, and discloses whitening gel based on biological polysaccharide and a preparation method thereof, the whitening gel comprises the following raw materials: hyaluronic acid, deionized water and thunberg fritillary bulb polysaccharide microcapsules; wherein the bulbus fritillariae thunbergii polysaccharide microcapsule is prepared by taking konjac glucomannan, chitosan and perillaldehyde modified hyaluronic acid as a shell layer and embedding bulbus fritillariae thunbergii polysaccharide and glabridin as a core material; the perillaldehyde modified hyaluronic acid is prepared by reacting alkenyl hyaluronic acid with perillaldehyde under the action of an initiator; the alkenyl hyaluronic acid is prepared by reacting hyaluronic acid with glycidyl methacrylate under the action of a catalyst. The prepared whitening gel has excellent whitening, moisturizing, anti-oxidation and anti-aging effects, effective components are not prone to loss, and the whitening gel can be applied to the skin surface for a long time, plays a whitening role and delays the aging process of the skin.

The invention provides a traditional Chinese medicine fermentation extracting solution and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine cosmetics. A traditional Chinese medicine composition which is composed of sophora flower bud, clove, honeysuckle, citron, astragalus membranaceus, houttuynia cordata, turmeric, emblic leafflower fruit, rehmannia and roselle and has an anti-aging effect is reasonably combined, and the traditional Chinese medicine fermented extract is obtained after the traditional Chinese medicine composition is fermented for multiple times by utilizing compound probiotics. The traditional Chinese medicine fermentation extract has a strong free radical scavenging effect, has an obvious improvement effect on cell activity, can obviously inhibit matrix protease activity, can obviously improve MDA content in serum of an aging mouse model and indexes of SOD, CAT, GSH-Px activity and the like, and has obvious anti-oxidation and anti-aging effects. The traditional Chinese medicine fermentation extracting solution provided by the invention can be used for preparing anti-aging cosmetics or functional foods, is safe and non-irritant when being used for human skin, and has an obvious improvement effect on the elasticity, wrinkles and smoothness of the human skin.

The invention discloses a preparation method of sturgeon roe peptide freeze-dried powder with an anti-aging effect. The preparation method specifically comprises the following steps: (1) unfreezing sturgeon roes, adding water, uniformly stirring, grinding and crushing, and adjusting the pH value; (2) heating and naturally cooling; (3) adding alkaline protease, uniformly stirring, carrying out enzymolysis, and adding starch sodium octenylsuccinate and vitamin E powder; (4) carrying out enzyme inactivation, naturally cooling, and adjusting the pH value; (5) carrying out rough filtration and centrifugal treatment, taking supernate, adsorbing, filtering and taking filtrate; and (6) carrying out plate frame filtration, taking filtrate, carrying out vacuum freeze drying, screening and packaging, thereby obtaining the product. The preparation method disclosed by the invention has the advantages of simplicity and convenience in operation, low cost, high embedding yield and the like, and has important significance in improving the stability and biological activity of the sturgeon roe peptide. Moreover, the sturgeon roe peptide freeze-dried powder has an anti-aging effect, and can be widely applied to oral liquid, solid beverages, tablet candies and the like in common foods.

The invention provides a composition with an instant and long-acting anti-aging effect and application thereof. The composition comprises a component A, a component B and a component C, the mass ratio of the raw materials is (1-10): (1-4): (0.05-0.2); the component A is prepared from the following components in parts by weight: 0.01 to 0.5 part of acetyl octapeptide-3, 0.01 to 0.5 part of dipeptide diaminobutyryl benzyl amide diacetate, 0.001 to 0.2 part of arginine / lysine polypeptide, 0.3 to 1 part of caprylyl glycol and 96 to 100 parts of water; the component B is prepared from the following components in parts by weight: 0.001 to 0.2 part of soluble collagen, 5 to 30 parts of glycerol, 0.01 to 0.5 part of sodium dihydrogen phosphate, 0.001 to 0.2 part of disodium hydrogen phosphate and 65 to 100 parts of water; and the component C is tripeptide-29. According to the invention, the quadruple wrinkle fading polypeptide is adopted to block wrinkles in a multi-target full-link manner, so that the product has a very good effect of fading various wrinkles in real time.

The invention discloses a lipophilic liposome containing polydeoxyribonucleotide as well as a preparation method and application of the lipophilic liposome. The lipophilic liposome comprises the following components in parts by weight: 0.001-3 parts of polydeoxyribonucleotide; 0.5 to 3 parts of phospholipid; 0.1-2 parts of a cationic emulsifier; 0.1-3 parts of an anionic emulsifier; 40 to 70 parts of polyol; the total amount is 100 parts. According to the invention, an emulsifier system formed by combining lecithin with anionic and cationic compound surfactants is adopted, so that the transdermal absorption of PDRN is facilitated. The lipophilic liposome containing polydeoxyribonucleotide prepared by the invention can effectively resist nuclease degradation, prolong the acting time of PDRN in skin, and improve the skin anti-aging and repairing effects of the liposome. The anti-aging effect of the active ingredients is improved, and the bioavailability of the active ingredients is improved. The cosmetic composition can be widely applied to cosmetic formulas of various dosage forms.

The invention relates to a ginseng, ganoderma lucidum and red date preparation with anti-oxidation and anti-aging effects and application thereof, and belongs to the field of health-care food, and the preparation comprises a ganoderma lucidum polysaccharide extract, a ginseng extract and a red date polyphenol extract. According to the method, the high-voltage pulsed electric field is combined with the Sevage method to extract the ganoderan, the extraction efficiency and purity can be improved while the biological activity of the ganoderan is maintained, and the method has the advantages of being short in time, low in cost, easy and convenient to operate and the like and is suitable for industrial production. Meanwhile, the synergistic effect of the components is achieved, the optimal anti-oxidation and anti-aging effects are achieved, and the prepared ginseng, lucid ganoderma and red date oral liquid preparation has the excellent anti-oxidation and anti-aging effects.

The invention discloses a composition with moisturizing and anti-aging effects and application of the composition in cosmetics, the moisturizing and anti-aging composition comprises retinyl sodium hyaluronate and a radix semiaquilegiae extract, and tests prove that the retinyl sodium hyaluronate and the radix semiaquilegiae extract have a synergistic effect, so that the moisturizing and anti-aging effects are achieved. The compound has a remarkable effect of promoting expression of an X VII type collagen gene and generation of AQP3 protein (aquaporin 3), can be used in cosmetics to improve the problems of dry skin and aging, and is good in stability, safe and non-irritant.

The invention relates to an anti-aging composition, a skin care product and a preparation method of the anti-aging composition and the skin care product. The anti-aging composition is prepared from the following components in parts by weight: 0.05 to 0.20 part of collagen, 0.05 to 0.20 part of elastin, 0.10 to 3.00 parts of water lily flower extract, 0.50 to 2.20 parts of folium mori extract, 0.50 to 2.40 parts of rhizoma dioscoreae extract and 1 to 10 parts of beta cyclodextrin. Compared with the prior art, the water lily extract, the mulberry leaf extract and even elastin have the capability of scavenging free radicals, and the Chinese yam extract has the capability of activating human body to synthesize collagen, so that the anti-aging effect is very remarkable through the synergistic interaction of the water lily extract, the mulberry leaf extract and even elastin; external supplement of collagen is matched with an internal synthesis effect, so that the collagen accumulation speed in the skin is greatly increased, the number of wrinkles is effectively reduced, and the anti-aging effect is improved.

The invention discloses a preparation method of a mesenchymal stem cell exosome based on microcarrier three-dimensional culture and application of the mesenchymal stem cell exosome in anti-aging skin care products. According to the method, a three-dimensional culture system of mesenchymal stem cells is optimized, and the anti-aging function activity of the subsequently separated and purified exosome is remarkably improved by adopting a microcarrier with recombinant collagen as a main component; subsequently, by optimizing an exosome separation and purification technology, and through a specific separation and purification mode and conditions, the exosome with anti-aging active ingredients is further obtained. Experiments prove that the exosome obtained by the method disclosed by the invention can effectively remove metalloproteinase 1 and promote collagen regeneration, has a remarkable anti-aging effect, is suitable for essence, face cream and other dosage forms, and has a wide market prospect.

The present invention discloses an anti-aging composition, an anti-aging cosmetic and its preparation method and application. The anti-aging composition includes torreya grandis oil, hydrolyzed Brazil nut protein, angoloside C, carnosic acid and nanovesicle excipients. The present invention uses the above four natural plant components as anti-aging active ingredients, and from multiple perspectives such as promoting collagen synthesis, inhibiting the expression of inflammatory factors, scavenging free radicals, and repairing DNA damage, it exerts a significant anti-aging effect. The present invention encapsulates the above anti-aging active ingredients in the form of nanovesicles, which not only improves the stability of the active ingredients, but also improves the skin absorption effect of the active ingredients. The liposome nanovesicles have good compatibility with the matrix of the cosmetic, effectively solving the compatibility problem between the active ingredients and the cosmetic matrix.

The invention provides a preparation method and application of mesenchymal stem cell exosomes, and the method is characterized in that N-acetylcysteine and quercetin are added into a culture medium used for culturing MSC cells, so that the MSC cells are stimulated to generate exosomes with anti-aging and anti-apoptosis effects. In addition, the exosome generated by stimulating the MSC through a culture mode of gradually reducing oxygen partial pressure further has an anti-aging effect; the adverse effects of acute oxidative stress, decline of multiplication capacity, unstable quality and the like in a low-oxygen state can be inhibited, and the activity of related components of cells and exosomes is not damaged. The method shows good anti-aging and anti-apoptosis effects in vitro, and a new thought is provided for treating aging diseases by the exosome in the future.

The invention relates to a ginseng and ganoderma lucidum preparation with anti-oxidation and anti-aging effects and application of the ginseng and ganoderma lucidum preparation with the anti-oxidation and anti-aging effects, ginseng and ganoderma lucidum are used as main components, and the ginseng and ganoderma lucidum preparation with the anti-oxidation and anti-aging effects is obtained through a specific preparation technology.

The invention discloses a synergistic anti-wrinkle, firming and anti-inflammatory composition as well as a preparation method and application thereof, and relates to the technical field of daily chemical products. The synergistic anti-wrinkle, firming and anti-inflammatory composition comprises the following components: a rambutan peel extract, a roxburgh rose fruit extract and a kangaroo claw extract. According to the synergistic anti-wrinkle, firming and anti-inflammatory composition and the preparation method and application thereof, the composition has a powerful anti-aging effect, after the rambutan peel extract, the kangaroo claw extract and the rosa roxburghii tratt fruit extract are compounded, the anti-aging and anti-inflammatory synergistic effect can be achieved, and the anti-wrinkle, firming and anti-inflammatory effects are achieved. And compared with any component independently used or a combination of two components, the composition has stronger anti-aging and anti-inflammatory effects.

The invention relates to a light loss repairing composition for improving skin resistance and application of the light loss repairing composition, and belongs to the technical field of cosmetics. The light loss repairing composition for improving the self resistance of the skin comprises the nannochloropsis oculata extract, the butterflybush flower extract and the bisabolol, all the components have a synergistic effect, ultraviolet light and blue light can be protected, and the light loss repairing composition has an anti-light aging effect and can be used for repairing the self resistance of the skin. And the mask has the effects of repairing skin barrier, relieving skin inflammation, improving redness, preventing hyperpigmentation, resisting aging, tightening skin, improving skin state and the like, and has the effect of improving self resistance of the skin.

The invention belongs to the technical field of cosmetics, and particularly relates to an EGCG-DNA sodium composition with anti-oxidation and anti-aging effects and application of the EGCG-DNA sodium composition. The EGCG-DNA sodium composition is prepared from the following components in parts by weight: 0.5 to 2 parts of EGCG-DNA inclusion, and 0.5 to 2 parts of PDRN (Protein Deoxyribose Nucleic Acid) from rose. An EGCG-DNA sodium inclusion is wrapped by adopting a specific nano wrapping technology, the problems that DNA sodium is large in molecular weight and impermeable and EGCG is unstable are solved, then the rose-sourced DNA sodium is matched with one another and has a synergistic effect in a preferable dosage range, free radicals are effectively resisted, and the skin aging problem is solved.

The invention relates to the technical field of cosmetics, in particular to a composition, a reagent, application of the composition and the reagent, a generation accelerant of type I collagen and type III collagen and cosmetics. The composition is prepared from the following components in parts by weight: 0.001 to 0.55 part of palmitoyl tripeptide trifluoroacetate, 0.001 to 1 part of methylsilanetriol and 0.001 to 0.55 part of snake venom-like tripeptide. According to the technical scheme provided by the invention, not only can the mitochondrial function be adjusted, but also the expression of HSP47 protein can be promoted, so that the collagen generation of dermis is promoted, the length and the quantity of nasolabial folds are reduced, the skin elasticity is improved, and a good anti-aging effect is shown.

The invention provides an anti-aging composition and application thereof, the composition at least contains pyrroloquinoline quinone disodium salt, ergothioneine and 5-aminolevulinic acid or salt thereof in physiologically acceptable media, the composition contains PQQ, ergothioneine and 5-aminolevulinic acid (5-ALA) or salt thereof, the three components are compounded to achieve a synergistic effect, and the anti-aging effect is achieved. The dyeing intensity of beta-galactosidase is reduced, and the anti-aging effect is achieved.

A circadian rhythm-based time-sharing repair formula and use thereof. A day composition focuses on anti-oxidation, stress resistance and energy metabolism to resist oxidative damage and enhance day vitality and provide long-lasting antioxidation protection. A night composition focuses on DNA repair, anti-inflammation and nerve relaxation to promote cell regeneration and repair and continuously support night repair. The composition of the day composition and the night composition designed according to the circadian rhythm of human metabolism causes the corresponding activities to take effect at the best time, and components are designed to cooperate with each other according to different physiological needs during the day / night, which can greatly improve the anti-aging effect.

The invention provides a composition for delaying senescence by activating telomerase activity. The composition is prepared from the following raw materials in parts by weight: 12.5 parts of wheat germ concentrated powder, 0.25 to 5 parts of ergothioneine, 0.25 to 5 parts of pyrroloquinoline quinone disodium salt and 0.25 to 5 parts of alpha-ketoglutaric acid. The invention further provides a preparation method and application of the composition for delaying senescence by activating telomerase activity. Through the synergistic effect of the ergothioneine and the pyrroloquinoline quinone disodium salt, the telomerase activity can be activated, the telomerase expression can be improved, the telomere length can be maintained, and the effect of delaying senescence can be achieved, so that the functional metabolism of a human body can be promoted, and the health state of the body can be improved; through the synergistic effect of the wheat germ concentrated powder and alpha-ketoglutaric acid, cell aging can be delayed; through the multi-target synergistic effect of'telomerase activation + mitochondrial repair + autophagy enhancement ', the anti-aging effect is delayed, the metabolic capability is high, the anti-aging effect is good, and safety and high efficiency are achieved; belongs to the technical field of food and health care product processing.

The invention discloses an anti-aging composition, a preparation method and application of the anti-aging composition in skin aging resistance, belongs to the technical field of cosmetics, and aims at solving the problems that in related technologies, anti-aging cosmetics are instable in functional components, and the skin aging resistance of transdermal absorbability and functional component combination needs to be further improved. The anti-aging composition is prepared from the following components in percentage by total weight of the composition: 10 to 20 percent of an anti-aging functional composition and 80 to 90 percent of an auxiliary material matrix, the composition with the anti-aging effect is prepared from the following main components: ascorbyl tetraisopalmitate, epigallocatechin gallate, hydroxytyrosol, a calendula extract, curcumin, resveratrol and glutathione. The anti-aging composition prepared by the invention has good stability, transdermal absorbability and capability of improving skin aging resistance.

The invention relates to a composition with anti-inflammatory and anti-aging effects and application thereof, the composition comprises a dogwood extract, a radix fici simplicissimae extract and a guava extract, the composition can effectively scavenge free radicals, inhibit collagenase activity and inhibit generation of fluorescent AGEs, and the composition has the anti-inflammatory and anti-aging effects. Skin aging and skin laxity and darkness caused by glycosylation reaction are prevented. Meanwhile, by inhibiting NO secretion, the composition relieves skin inflammation reaction and can also improve skin microcirculation. All the components have a synergistic effect, so that the anti-oxidation, anti-inflammatory, anti-aging and anti-saccharification effects are remarkably enhanced, and the skin problems are comprehensively solved. No organic solvent is used in the process, the green and environment-friendly concept is met, the safety and reliability of the extract are ensured, and a mild and efficient solution is provided for anti-aging.

The invention discloses an anti-inflammatory and anti-aging composition containing a crocus sativus extract and application of the anti-inflammatory and anti-aging composition, and relates to the technical field of cosmetics, the anti-inflammatory and anti-aging composition comprises the crocus sativus extract, a kangaroo claw extract, a dendrobium devonianum stem extract and adenosine; the anti-inflammatory and anti-aging composition can promote human dermal fibroblasts to secrete III-type collagen, can promote human dermal fibroblasts to proliferate and improve the anti-oxidation and anti-inflammatory capacity of the human dermal fibroblasts, has certain anti-inflammatory and anti-aging effects, and can be widely applied to cosmetics with the anti-inflammatory and anti-aging effects.

The invention provides microcapsule seasoning powder containing active plant components for cats and a preparation method of the microcapsule seasoning powder, the microcapsule seasoning powder comprises a double-layer embedding system, and the microcapsule seasoning powder comprises the following raw material components in percentage by weight: 10-14 wt% of a composite core material, 32-36 wt% of a multifunctional food calling base material, 35-39 wt% of the double-layer embedding system and 14-16 wt% of functional auxiliary materials; the composite core material is prepared by compounding a mint extract, a green tea extract, a chicory extract, a mulberry leaf extract and a hawthorn extract according to the mass ratio of (1.8-4.5): (1.2-3): (0.8-1.5): (0.5-1.2): (1-2). The cat food has a dual-stage targeting effect of low release in the stomach and high release in the intestinal tract, has high palatability, has the effects of promoting the health of the intestinal tract, improving metabolism and resisting aging synergistically, is long-acting and stable, and can be suitable for various types of functional foods for cats.