1134 results about "Skin barrier" patented technology

The invention provides an anti-dandruff composition based on double barrier repair as well as a preparation method and application thereof, and relates to the technical field of shampoo supplies, the anti-dandruff composition comprises the following effective components: at least two of isodon amethystoides extract, polygonum capitatum extract and myrobalan extract. The compound has a synergistic antibacterial effect, still has a synergistic antibacterial effect after being compounded with OCT, and can be used for replacing or cooperating with OCT, so that the dosage of OCT is reduced, and the irritation is reduced; the anti-dandruff composition has the advantages that the anti-dandruff effect is good, the DPPH free radical scavenging capacity of the anti-dandruff composition is better than that of OCT, the isodon amethystoides extract, the polygonum capitatum extract and the fructus chebulae extract are plant extracts and have no irritation to scalp, the whole anti-dandruff composition has no irritation to the scalp, and the technical problems that in the prior art, anti-dandruff products have certain influences on skin barriers, and the long-acting anti-dandruff effect cannot be achieved are solved.

The present invention provides a Lactiplantibacillus plantarum ( Lactiplantibacillus plantarum ), strain 24, which is deposited in the China General Microbiological Culture Collection Center, deposit number: CGMCC No. 31278. The Lactiplantibacillus plantarum 24 of the present invention can secrete sphingomyelinase to promote the production of ceramide in HaCaT cells; Lactiplantibacillus plantarum 24 or its metabolite or its lysate can up-regulate the expression of key enzymes in the sphingomyelinase and / or ceramide synthesis pathway of skin cells, repair the skin barrier; down-regulate the expression of pro-inflammatory cytokines, inhibit autophagy, and has a good anti-inflammatory effect; at the same time, it also has good antioxidant and whitening effects. The Lactiplantibacillus plantarum 24 or its metabolite or its cell lysate of the present invention can be used in the preparation of products having the above-mentioned effects or functions.

The invention provides a composition with oil-controlling, acne-removing, barrier-repairing effects and application thereof, and belongs to the field of cosmetics. The composition is prepared from a baropetalum beetle leaf extract, a roselle flower extract, totarol and a cryptomeria fortunei bud extract. The baropetalum chinense leaf extract has the effects of balancing grease secretion and shrinking pores; the roselle flower extract is rich in organic acid and anthocyanin, and has the effects of dissolving pore keratosuppository, controlling oil, resisting inflammation, smoothing acne skin, preserving moisture and removing redness; as a bacteriostatic agent, totarol has a natural preservative effect on gram-positive bacteria and partial negative bacteria, and has the effects of removing acnes, sterilizing, diminishing inflammation, whitening and the like; the cryptomeria fortunei bud extract can promote skin tissue structure regeneration and strengthen skin barriers. The composition effectively regulates and controls excessive secretion of sebaceous gland grease and pox skin specific protein through the synergistic effect of various components, promotes the health of pox skin, repairs the skin barrier and enhances the self-protection ability of the skin at the same time.

The invention relates to a novel application of animal bifidobacterium subsp. Lactis BGI-N3, in particular to an application of the animal bifidobacterium subsp. Lactis BGI-N3 in preparation of a preparation for relieving skin allergy. The invention finds that the bifidobacterium animalis subsp. Lactis BGI-N3 has a very remarkable effect in the aspect of relieving skin allergy, and the effect is specifically shown as follows: in an atopic dermatitis animal model, the dermatitis score, scratching times and percutaneous water loss are remarkably reduced, and the atopic dermatitis skin tissue damage condition is relieved; the immune organ edema condition is improved, the levels of Th2 type cell factors and inflammatory factors IL-6, TNF-alpha and IFN-gamma related to dermatitis are reduced, and the immune balance of the body is recovered; expression of fibroin and endothelial protein in skin tissue is improved, and the skin barrier is repaired; the level of antibacterial peptide in skin tissues is recovered, and the antibacterial activity of the skin is enhanced. Meanwhile, compared with a traditional chemical medicine for treating atopic dermatitis, the animal bifidobacterium subsp. Lactis BGI-N3 has no side effects such as weight loss, immune organ atrophy, immune imbalance and the like.

The invention provides a lactobacillus plantarum 24 which is preserved in the general microbiological center of the China Committee for Culture Collection of Microorganisms, and the preservation number of the lactobacillus plantarum 24 is CGMCC No.31278. The lactobacillus plantarum 24 has the advantages that the lactobacillus plantarum 24 is prepared from lactobacillus plantarum, lactobacillus plantarum, lactobacillus plantarum, lactobacillus plantarum, lactobacillus plantarum, lactobacillus plantarum, lactobacillus plantarum and lactobacillus plantarum; the plant lactobacillus 24 disclosed by the invention can secrete sphingomyelinase and promote HaCaT cells to generate ceramide; the plant lactobacillus 24 or the metabolite or lysate thereof can up-regulate expression of key enzymes in a synthetic route of skin cell sphingomyelinase and / or ceramide, and repair a skin barrier; expression of proinflammatory cytokines is lowered, autophagy is inhibited, and a good anti-inflammatory effect is achieved; meanwhile, the anti-oxidation and whitening effects are relatively good. The plant lactobacillus 24 or the metabolite or the cell lysate of the plant lactobacillus 24 can be applied to preparation of products with the effects or the effects of the plant lactobacillus 24 and the metabolite or the cell lysate of the plant lactobacillus 24.

The invention relates to a composition containing ceramide and collagen tripeptide and a preparation method thereof, and belongs to the technical field of health care products. The invention discloses a composition containing ceramide and collagen tripeptide. The composition is prepared from the following raw materials: collagen tripeptide, rice bran oil powder, a herba houttuyniae extract, pineapple powder, konjaku flour, a grape seed extract, olive fruit powder, carnosine, pomegranate concentrated powder and a whey fermentation product. The grape seed extract, the olive fruit powder, the carnosine and the pomegranate concentrated powder inhibit the Maillard reaction of the collagen peptide and improve the utilization rate of collagen tripeptide; ceramide rich in the rice bran oil powder is a natural skin moisturizing factor, and is matched with the pineapple powder and the konjaku flour which have a keratin metabolism effect to maintain the health of cuticles; the herba houttuyniae extract and the whey fermentation product are matched to have an excellent anti-inflammatory effect, so that the components enhance the skin barrier in multiple dimensions through collagen synthesis, cuticle maintenance, anti-inflammatory and anti-oxidation.

The invention discloses a composition with tightening, wrinkle fading, soothing and repairing effects and application of the composition. The composition with the effects of tightening and fading wrinkles and relieving and repairing is prepared from a lactobacillus fermentation product, hexanediol, fully human collagen, glycosylglycerol, a citrus peel extract, a palmitoyl tripeptide-5 solution, a chrysanthemum extract and SPG beta-glucan. According to the invention, seven active material raw materials including the lactobacillus fermentation product, the fully human collagen, the glycosylglycerol, the citrus peel extract, the palmitoyl tripeptide-5 solution, the chrysanthemum extract and the SPG beta-glucan are creatively combined for use, and the seven raw materials supplement each other and have a synergistic effect; the effects of lightening skin wrinkles, improving skin barriers and relieving skin sensitivity are achieved from multiple dimensions, and cosmetics prepared from the composition have the effects of repairing, relieving, tightening and resisting wrinkles.

This invention provides a transdermal nanoparticle delivery system for skin anti-inflammation, comprising a protein-blue calyx methyl ether-polymer shell capsule composite structure. The protein has an affinity for the skin, blue calyx methyl ether is loaded within the protein, and the polymer layer coats the surface of the protein. The blue calyx methyl ether nanoparticle transdermal delivery system has a size of 30-80 nm, and the polymer shell thickness is 10-35 nm. The surface properties of the polymer shell can be controlled according to the required transdermal delivery depth, enabling the protein to penetrate the skin barrier and be efficiently delivered deep into the skin, where the blue calyx methyl ether is then slowly released, targeting and alleviating skin inflammation. This addresses the drawback of low therapeutic efficacy of blue calyx methyl ether in treating skin inflammation due to unsatisfactory transdermal effects.

The invention relates to an aloe extract nano-vesicle as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The aloe extract nano-vesicle provided by the invention is a nano-micelle formed by an aloe extract and tocopheryl acetate, the particle size of the aloe extract nano-vesicle is 280 to 500 nm, the Zeta potential of the aloe extract nano-vesicle is-10.12 to-11.34 mV, and the polydispersity coefficient of the aloe extract nano-vesicle is 0.239 to 0.434. The aloe extract nano-vesicle disclosed by the invention has a nano-scale size, and can easily penetrate through a skin barrier and enter skin cells, so that the moisturizing effect of the aloe extract nano-vesicle is achieved. The permeability of the moisturizing composition is far better than that of the traditional moisturizing composition, so that the required moisture can be more effectively provided for the skin. The aloe extract nano-vesicle can carry other active ingredients such as moisturizing factors to deeply permeate into skin, comprehensive care is provided for the skin, the texture and appearance of the skin are improved, the preparation process is simple, and the aloe extract nano-vesicle is suitable for technological production.

The invention relates to bionic skin barrier cream with a three-layer phospholipid structure and a preparation method of the bionic skin barrier cream, and belongs to the technical field of cosmetics, the bionic skin barrier cream comprises the following raw materials: lecithin, wax ester, triglyceride, composite ceramide, phytosterol oleate, squalane, an antioxidant, polyol, composite amino acid, pyrrolidone carboxylic acid, urea and arginine. A stabilizing agent, a treating agent and the balance of deionized water. The bionic skin barrier cream prepared by the invention has a three-layer phospholipid structure, and compared with a double-layer phospholipid structure in the market, the firmness and hydrophobicity of the double-layer structure are further improved by the added third-layer structure, so that the prepared bionic skin barrier cream has outstanding waterproof, sweat-resistant and light pollution-resistant effects; in addition, the wax ester, the triglyceride, the phytosterol oleate, the pyrrolidone carboxylic acid and the urea selected in the invention have a synergistic effect, and can generate excellent moisturizing and repairing effects and certain protection effects.

The invention discloses a composition with high ultraviolet damage resistance as well as a preparation method and application thereof, and particularly belongs to the technical field of skin care product raw materials. The composition with high ultraviolet damage resistance is prepared by performing solid-state fermentation on radix scutellariae roots, radix ligustici sinensis and radix puerariae through compound bacteria consisting of bacillus subtilis, lactobacillus bulgaricus and bacillus coagulans and then performing solvent extraction. The composition with high ultraviolet damage resistance has excellent effects of resisting oxidative damage and inhibiting inflammatory factors, and can achieve the effects of repairing skin barriers, resisting inflammation, relieving, efficiently promoting repair of after-sun skin and the like.

The present invention belongs to the technical field of protein engineering. Provided are a recombinant type XVII collagen having a triple helix structure and the use thereof. The amino acid sequence of the recombinant type XVII collagen comprises n core units, wherein n is the integer 1 or an integer greater than 1, and the amino acid sequence of the core units is as shown in SEQ ID NO: 1. Further provided are a method for constructing a plurality of expression systems and a method for preparing the recombinant type XVII collagen. Further provided is the actual industrial application on the basis of the characteristics of the protein. The provided recombinant type XVII collagen exhibits high purity, good thermal stability and high biological activity, and has a molecular weight much smaller than that of natural collagen, thereby reducing the difficulty for the collagen to cross the skin barrier and exert biological functions. Experiments show that the recombinant type XVII collagen has a variety of biological activities such as promoting cell migration.

The invention relates to the technical field of cosmetics, in particular to application and a synthesis method of cyclic peptide. The inhibition objects of the cyclic peptide comprise IL-1beta, IL-6 and TNF-alpha (Tumor Necrosis Factor-alpha); when the concentration is less than or equal to 10ppm, the inhibition rate on IL-1beta is greater than or equal to 40%, the inhibition rate on IL-6 is greater than or equal to 50%, and the inhibition rate on TNF-alpha is greater than or equal to 40%. The cyclopeptide has a barrier repairing effect and can improve FLG expression; meanwhile, the moisturizing effect is achieved, and percutaneous moisture loss of the skin can be reduced. The invention provides a group of cyclic peptides, which has excellent anti-inflammatory, moisturizing, barrier repairing and soothing effects, and compared with the existing straight-chain peptides in the market, the group of cyclic peptides has more obvious anti-inflammatory and soothing effects, and has a certain skin barrier repairing effect. The group of cyclic peptides can be applied to the fields of cosmetics and skin care products, and the product efficacy is improved; and the synthetic method of the cyclic peptide is easy to implement and wide in application prospect.

The invention provides a preparation method of a recombinant collagen dressing, and belongs to the technical field of medical dressings. According to the technical scheme, stacked short sequences and continuous human collagen amino acid short sequences are repeatedly combined for multiple times to form recombinant collagen with specificity, and high similarity of the recombinant collagen with human collagen is ensured. On the basis, 4-FPBA is used as a cross-linking agent to respectively form a Schiff base bond responsive to pH and a boric acid ester bond responsive to glucose with CMCS and two kinds of HA with different molecular weights, and then the double-dynamic covalent cross-linked network adhesive hydrogel is synthesized. The triple-helix structure of the recombinant collagen is combined with a specific receptor on a cell membrane, and cell behaviors are regulated and controlled by inducing signal transduction through a cytoskeleton, so that skin microcirculation can be effectively improved, and a skin barrier can be repaired; the hydrogel dressing matrix has the effects of resisting inflammation, resisting oxidation, resisting bacteria, promoting healing and the like, the biological performance of the dressing is remarkably improved, and a better curative effect is achieved.

Provided are methods and composition for treating skin barrier functions and associated disorders. Formulated compositions may be applied on human skin to maintain a desired skin surface pH over an extended period of time without irritating the skin. Maintaining the desired surface pH aids in treatment of eczema, in addition to other skin conditions.

The invention discloses a barrier repair composition applicable to dry sensitive skin and application thereof. The composition comprises a golden camellia extract, a loquat leaf extract, an alfalfa extract and hydrolyzed royal jelly protein. According to the barrier repairing composition applicable to the dry sensitive skin, disclosed by the invention, through reasonable matching and synergistic interaction of all the components, a better skin barrier repairing effect can be achieved, so that the problems of dry and tight skin, desquamation, erythema, itching, dull luster, redness, burning heat sensation, pricking pain and the like of the dry sensitive skin are fundamentally solved.

The invention relates to a silk fibroin gel dressing and a preparation method and application thereof, the silk fibroin gel dressing comprises a silk fibroin gel dressing main body formula, and the silk fibroin gel dressing main body formula comprises water, silk fibroin, an inducer, a protective agent and a thickening agent; wherein the mass fraction of the silk fibroin is 0.1%-5%, the mass fraction of the inducer is 1%-40%, the mass fraction of the protective agent is 1%-10%, the mass fraction of the thickening agent is 0.1%-2%, and the balance is water. The prepared silk fibroin gel dressing is easy to smear and absorb and does not need to be cleaned; compared with traditional dressings, safer components are adopted, and the dressing is mild, painless and non-irritant; through the synergistic effect of the various components, multi-dimensional protection can be formed on the skin surface, the skin barrier injury can be repaired, the effects of moisturizing, relieving, red fading and stability maintaining are achieved, postoperative skin discomfort can be relieved, and wound healing can be promoted.

The invention provides an in-vitro skin blood vessel immune model as well as a preparation method and application thereof. THP-1 human monocyte leukemia cells are induced to be differentiated into M0 type macrophages, and then the M0 type macrophages are respectively induced into M1 type macrophages and / or M2 type macrophages; then co-culturing the M1 type and / or M2 type macrophages and vascular endothelial cells to form a vascular immune model; finally, the 3D skin model is placed on the blood vessel immune model, external stimulation is conducted, and the in-vitro skin blood vessel immune model is constructed. The in-vitro skin blood vessel immune model can be used for repairing skin barriers, inflammation pathways, blood vessel metabolism, the expression level of genes or proteins related to extracellular matrixes, vascular endothelial cells, the proliferation and migration ability of activated macrophages and the like. The seven feature dimensions of the physiological structure feature of the skin model are used for screening the to-be-tested sample and exploring the action mechanism, and the method has the characteristics of rapidness, multiple screening dimensions, high accuracy, low construction difficulty, low cost and high universality.

The invention belongs to the technical field of microorganisms, and particularly relates to an extracellular vesicle of phytobacterium plantarum and application of the extracellular vesicle. Specifically, the plant lactobacillus extracellular vesicles can promote HaCaT cells to generate ceramide, up-regulate expression of key genes in a skin ceramide synthesis route and recover a skin barrier; the expression of proinflammatory factors in a cell inflammation model can be reduced, and a relatively good anti-inflammatory effect is achieved. A mouse skin injury model verifies that the EVs has good skin infiltration capacity and can remarkably reduce the skin injury score, relieve skin itch, improve the skin water content and reduce expression of proinflammatory factors in skin tissue and expression of pruritus-related cell factors.

The invention discloses an anti-wrinkle composition containing recombinant collagen as well as a preparation method and application of the anti-wrinkle composition, and belongs to the technical field of cosmetics and skin care products. The composition is prepared from the following active ingredients in percentage by mass: 0.01 percent to 20 percent of recombinant humanized I type collagen, 0.01 percent to 20 percent of recombinant humanized III type collagen, 0.01 percent to 10 percent of recombinant humanized XVII type collagen and 0.01 percent to 20 percent of space breeding desert algae extract. The three kinds of recombinant humanized collagen and the space breeding desert algae extract form a compound system, and when the total mass ratio of the three kinds of recombinant humanized collagen and the space breeding desert algae extract is within a specific range of 1.3: 1-4: 1, the three kinds of recombinant humanized collagen and the space breeding desert algae extract can achieve synergistic interaction to improve the skin barrier function. Based on the synergistic mechanism of the compound system, the composition disclosed by the invention can effectively promote and enhance the skin moisturizing and anti-wrinkle capability and repair the skin barrier, and is suitable for the development and application of anti-wrinkle, tightening and skin aging delaying skin care products.

The invention provides a glaucocalyxin A nano transdermal delivery system for skin inflammation resistance, which is of a capsule composite structure of protein, glaucocalyxin A and a polymer shell layer, the protein has an affinity effect on skin, glaucocalyxin A is loaded in the protein, the polymer layer coats the surface of the protein, the size of the glaucocalyxin A nano transdermal delivery system is 30-80nm, and the size of the polymer layer is 30-80nm. And the thickness of the polymer shell layer is 10-35 nm. The surface property of the polymer shell can be regulated and controlled according to the depth requirement of transdermal delivery, so that protein breaks through the skin barrier and is efficiently delivered to the deep position of the skin, the glaucocalyxin A is slowly released, the skin inflammation is relieved in a targeted mode, and the defect that the treatment effect is poor due to the non-ideal transdermal effect when glaucocalyxin A is used for treating the skin inflammation is overcome.

The invention relates to the technical field of cosmetics, in particular to soothing, repairing and moisturizing essence lotion and a processing method thereof. The soothing, repairing and moisturizing essence lotion comprises the following components in percentage by weight: 40-55% of a water phase component, 15-20% of an oil phase component, 6-10% of an emulsifier, 15-25% of a plant extract and 3-7% of an additive, deionized water and the oil-phase component form a stable O / W emulsion through an emulsifying agent, it is ensured that active ingredients are evenly released, a plant extract composed of a licorice root extract, a hamamelis virginiana extract, a centella asiatica extract and an aloe extract cooperates with betaine and the like in the water-phase component, inflammatory factors are inhibited, the skin barrier is repaired, and the skin care effect is achieved. The soothing, repairing and moisturizing essence lotion provided by the technical scheme has the advantages that the moisturizing degree is improved through squalane, a multi-layer moisturizing system is constructed through panthenol, sodium hyaluronate, beta-glucan and shea butter, water loss is reduced, and the soothing, repairing and moisturizing essence lotion provided by the technical scheme can comprehensively meet diversified requirements of sensitive skin and ensure that active ingredients are uniformly released.

The invention relates to the technical field of hydrogel, in particular to mussel mucoprotein loaded extracellular vesicle hydrogel as well as a preparation method and application thereof. The hydrogel is prepared by adopting a mode of combining human umbilical cord mesenchymal stem cell exosome Exo and mussel mucoprotein MAP; the method has the following advantages: 1, the wound repair effect is improved: the biological activity of the exosome Exo and the adhesion performance of the mussel mucin MAP are utilized to jointly promote the wound repair process, so that the repair effect is improved; 2, the adhesion performance is enhanced: the strong adhesion of the mussel adhesive protein MAP is utilized to ensure that the hydrogel can be tightly attached to the wound surface in a wet environment, and the dressing is prevented from falling off and infection risk; and 3, multifunctionality is realized: the composite hydrogel not only has the basic functions of promoting healing, resisting bacteria and the like, but also can transmit genetic information through exosome Exo, so that tissue regeneration and skin barrier repair are further promoted.

The invention discloses a plant-sourced anti-allergy soothing composition and application thereof, and belongs to the field of cosmetic processing.The plant-sourced anti-allergy soothing composition is prepared from hydrolyzed corn starch, saururus chinensis extract, carrot root extract and water-soluble hesperidin. Active ingredients of plant sources are deeply studied, and the anti-allergy soothing composition has the advantages that the plant-sourced anti-allergy soothing composition is prepared from the hydrolyzed corn starch, the saururus chinensis extract, the carrot root extract and the water-soluble hesperidin; a series of plant extracts with a synergistic effect are screened out, the plant-source multi-dimensional composition for relieving itching and repairing red is successfully researched and developed, and through the synergistic effect of the hydrolyzed corn starch, the saururus chinensis extract, the carrot root extract and the water-soluble hesperidin, the composition has the effects of relieving and repairing skin in a multi-dimensional mode, relieving itching and repairing red. In addition, the composition can repair the skin barrier for a long time and improve the tolerance of the skin, and meanwhile, the composition has good safety and stability and is suitable for various skin types, especially sensitive skin.

A protein carrier-based active ingredient transdermal delivery system, which is a small molecule active ingredient-protein-polymer composite structure and comprises a small molecule active ingredient, a protein loaded with the small molecule active ingredient, and a polymer coating a surface of the protein. The protein is modified with a polymerizable double-bond compound. After the loading of the small molecule active ingredient, a polymerization reaction is initiated on the surface of the protein in situ, so that the surface of the protein is coated with a polymer layer. The polymer layer is biologically friendly, and the surface properties of the polymer layer can be regulated and controlled according to the transdermal depth requirement, thereby achieving the targeted transdermal delivery of proteins and active small molecules while breaking through the skin barrier, and significantly overcoming the defect of poor delivery efficiency of previous protein-based delivery systems. The transdermal delivery system has a simple preparation method with a high yield, and thus can be industrially produced on a large scale.

The invention discloses a natural component composition for conditioning skin micro-ecology, a preparation method of the natural component composition and application of the natural component composition in skin care products for children. The composition comprises a synergistic combination of a sphingomonas fermentation product extract, a haematococcus pluvialis extract rich in astaxanthin, an abelmoschus esculentus fruit extract rich in polysaccharides, and a yeast / zinc fermentation product. The present invention provides improvements in astaxanthin in terms of chemical stability and transdermal permeability. The composition aims to enhance the immature skin barrier, provide a good effect, and support the healthy development of skin microecology, thereby solving the unique physiological needs of children's skin. The invention also describes a preparation method of the composition and application of the composition in cosmetics for children and dermatological products.

The invention relates to a cyclic tetrapeptide derivative as well as a preparation method and application thereof. The structural formula of the cyclic tetrapeptide derivative is shown as a formula (I), and R is selected from C7-C19 alkyl and C7-C19 unsaturated chain alkyl. The cyclic tetrapeptide derivative or the salt or the stereoisomer thereof provided by the invention can improve the contents of hyaluronic acid, silk protein and alpha-crystal protein of epidermal cells, so that the skin barrier can be effectively enhanced, the obvious repairing and improving effects on the skin are achieved, and compared with palmitic acid tetrapeptide-10, the cyclic tetrapeptide derivative or the salt or the stereoisomer thereof has better stability and safety, and can be used for preparing a medicine for treating skin diseases. And when being used in cosmetics, the composition can play a better role in repairing and enhancing the skin barrier, and has a better improvement effect on the skin. # imgabs0 # (I)

A skin care active substance and a skin care product. The skin care active substance comprises, in parts by weight, 0.1-15 parts of a moisturizing agent and 0.1-12 parts of a soothing agent, wherein the moisturizing agent comprises at least one of four-molecular-weight hyaluronic acid and D-panthenol, and the soothing agent comprises at least one of a Portulaca oleracea extract, dipotassium glycyrrhizinate, a Piper methysticum extract, and trans-4-tert-butylcyclohexanol. By designing the components and the ratio thereof, the synergistically formed active substance can mildly and effectively provide moisturizing, soothing, and repairing effects, thereby effectively protecting the skin barrier, maintaining skin health, and demonstrating high safety.

The invention relates to a light loss repairing composition for improving skin resistance and application of the light loss repairing composition, and belongs to the technical field of cosmetics. The light loss repairing composition for improving the self resistance of the skin comprises the nannochloropsis oculata extract, the butterflybush flower extract and the bisabolol, all the components have a synergistic effect, ultraviolet light and blue light can be protected, and the light loss repairing composition has an anti-light aging effect and can be used for repairing the self resistance of the skin. And the mask has the effects of repairing skin barrier, relieving skin inflammation, improving redness, preventing hyperpigmentation, resisting aging, tightening skin, improving skin state and the like, and has the effect of improving self resistance of the skin.

The invention discloses a composition containing cactus fermentation liquor and a preparation method and application of the composition in cosmetics, the cosmetic composition containing the cactus fermentation liquor comprises the cactus fermentation liquor, Ectoine and sodium hyaluronate according to a specific proportion, the cactus fermentation liquor is prepared by performing enzymolysis pretreatment on succulent stems of cactus, and the cactus fermentation liquor is prepared by performing enzymolysis pretreatment on the succulent stems of the cactus. Sequentially inoculating bacillus licheniformis and lactobacillus plantarum for sequential fermentation; and finally, purifying and enriching by ultrafiltration and nanofiltration two-stage membrane separation technologies. A product rich in small molecule active peptide and specific organic acid is obtained through biotransformation process combination, so that the final cosmetic composition has remarkable skin barrier repairing and anti-oxidation effects.