The invention discloses a collagen needle autologous repair medical mask and a preparation method thereof, and relates to the technical field of medical cosmetology. Comprising the following raw materials: 15-18% of water, 7-8% of glycerol, 5-8% of lecithin, 3-4% of propylene glycol, 7-8% of bio-saccharide gum, 6-6.5% of allantoin, 5-6% of isomalt, 3.5-4% of polysorbate, 4.5-5% of radix ophiopogonis, 6-7% of glycyrrhiza glabra root, 5-5.5% of cactus, 4-5% of aloe, 2.5-3% of scutellaria baicalensis root, 3-4% of carbomer, 1.5-2% of butanediol, 8-9% of soluble collagen and 6.5-7% of ceramide. And 2.5-3% of sodium hyaluronate. According to the collagen needle self-repairing medical mask and the preparation method thereof, the proliferation and regeneration capacities of cells are improved by moisturizing and resisting oxidation, and a breathable and fresh moisturizing layer is formed on the surface of skin, so that the collagen needle self-repairing medical mask has a synergistic effect with active ingredients of cell growth factors, the skin wound healing is promoted, the skin healing process is shortened, and the repairing of skin barriers is accelerated; pigment accumulation and precipitation after inflammation are relieved, the skin elasticity is improved, and the skin rapidly recovers the healthy state.