1713 results about "Dermatomal" patented technology

Camera and / or other sensor analysis of skin, used to diagnose and monitor health conditions. A computer, receiving skin data from a user, where the skin data is images and / or other data of the skin. The computer processes the skin data identify skin conditions, their status, and to compare the skin data with information indicative of health conditions that are not skin diseases. This can be done by finding similar skin data to other data received from other people who have specified health conditions and / or by looking for changes from previous images. The skin data can be captured by a smart phone camera (alone or with digital peripheral attachments) or a dedicated capture device such as a periscope, one way mirror, or cubicle. An augmented reality marking system can be used to mark areas on the user's skin to compare against other previous skin images and / or data.

The invention discloses a working method of skin thermal therapy equipment which is convenient to use and can realize intelligent startup work and an itching relieving instrument. According to the technical scheme, the working method of the skin thermal therapy equipment comprises the following steps that a, whether a designated area makes contact with the skin of a user or not is detected, and if yes, the step b is executed; and b, detecting the skin contact time and the skin temperature of the contacted part, and if the detected temperature is within a preset range and the continuous contact time reaches the set time, starting the skin thermal therapy equipment to operate.

Wearable modular mask systems for combination face and skincare diagnostics and therapeutics. Systems include devices that can be attached to wearable masks for diagnosis and treatment of skin conditions, diseases, and disorders, as well as for cosmetic improvements to the skin of the face and scalp.

The invention belongs to the technical field of cosmetics, and particularly relates to essence with anti-wrinkle, repairing and skin-brightening effects as well as a preparation method and application of the essence. The essence is prepared from the following components in parts by weight: 10 to 70 parts of herba centellae extract, 0.0015 to 0.04 part of crocus sativus extract, 0.5 to 2.5 parts of spirulina maxima extract, 0.015 to 0.2 part of radix gentianae extract, 0.1 to 1.5 parts of panthenol, 0.25 to 1.5 parts of leuconostoc / radish root fermentation product filtrate, 0.1 to 1.5 parts of carnosine and 0.21 to 5.3 parts of anti-wrinkle components. According to the essence, various effective components such as the centella asiatica extract, the spirulina maxima extract and the radix gentianae extract are matched for use, a unique composite formula is formed, all the components promote one another, the anti-wrinkle, repairing and skin brightening effects of the essence can be remarkably enhanced, and therefore all-around skin care is provided for consumers, and the essence has a good market prospect. The overall quality of the skin can be effectively improved.

The invention discloses a recombinant XVII type collagen engineering bacterium as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering, and the recombinant XVII type collagen engineering bacterium is realized through three steps of designing and optimizing collagen, improving translation through codon optimization and selecting a vector for cloning. By optimizing the amino acid sequence and the codon, the expression efficiency and the stability of the recombinant XVII type collagen in engineering bacteria are improved. The optimization not only improves the production efficiency of the protein, but also reduces the production cost. The recombinant XVII type collagen has potential in the medical field, especially in the fields of skin repair, wound healing, aging resistance and the like. Meanwhile, in the fields of beauty and biological materials, collagen is widely applied to products such as masks and skin care products as a basic component, and can promote skin cell regeneration and enhance skin elasticity and repair capacity.

The invention provides a composition with oil-controlling, acne-removing, barrier-repairing effects and application thereof, and belongs to the field of cosmetics. The composition is prepared from a baropetalum beetle leaf extract, a roselle flower extract, totarol and a cryptomeria fortunei bud extract. The baropetalum chinense leaf extract has the effects of balancing grease secretion and shrinking pores; the roselle flower extract is rich in organic acid and anthocyanin, and has the effects of dissolving pore keratosuppository, controlling oil, resisting inflammation, smoothing acne skin, preserving moisture and removing redness; as a bacteriostatic agent, totarol has a natural preservative effect on gram-positive bacteria and partial negative bacteria, and has the effects of removing acnes, sterilizing, diminishing inflammation, whitening and the like; the cryptomeria fortunei bud extract can promote skin tissue structure regeneration and strengthen skin barriers. The composition effectively regulates and controls excessive secretion of sebaceous gland grease and pox skin specific protein through the synergistic effect of various components, promotes the health of pox skin, repairs the skin barrier and enhances the self-protection ability of the skin at the same time.

The invention relates to the technical field of puncture needle training, and particularly discloses a medical simulation puncture needle training device which comprises a simulation arm, a simulation puncture part is arranged on the end face of the simulation arm, a simulation part is fixed in the simulation puncture part, and a simulation cavity is formed in the simulation part; the simulation device further comprises a simulation skin simulation assembly and a driving assembly, the simulation skin simulation assembly is arranged in the simulation cavity, the driving assembly is arranged on the side edge of the simulation skin simulation assembly, the simulation skin simulation assembly comprises a first skin layer arranged in the simulation cavity, and a second skin layer is arranged at the bottom of the first skin layer. The driving assembly works to adjust the tension of the first skin layer and the second skin layer, and the skin states of patients of various ages are simulated; adjusting operation of the elasticity degree of the second skin layer, the wrinkle degree of the first skin layer and the bending degree of the simulated blood vessel is achieved, a trainer can experience real touch of skins of different age groups on the same model, and intensified training is carried out in a targeted mode.

The invention discloses a monitoring method and system and a related device, which are applied to first electronic equipment, the first electronic equipment is provided with a first circuit, and the first circuit comprises a first electrode, a second electrode, a third electrode, a fourth electrode, an excitation current generation unit and a voltage measurement unit; receiving and responding to a first instruction, and determining that the first electrode and the second electrode are in good contact with skin through a first circuit; first information is determined through the first circuit, the first electrode makes contact with a first position of the user skin, the second electrode makes contact with a second position of the user skin, and the first position and the second position are located at the two ends of the thoracic cavity tissue respectively; and outputting first information, wherein the first information comprises one or more of the following items: cardiac output, stroke output, heart rate, ejection fraction and cardiac function judgment result. Therefore, the heart function condition of the user can be monitored in real time, and the user can conveniently monitor anytime and anywhere.

The invention discloses a composition with high ultraviolet damage resistance as well as a preparation method and application thereof, and particularly belongs to the technical field of skin care product raw materials. The composition with high ultraviolet damage resistance is prepared by performing solid-state fermentation on radix scutellariae roots, radix ligustici sinensis and radix puerariae through compound bacteria consisting of bacillus subtilis, lactobacillus bulgaricus and bacillus coagulans and then performing solvent extraction. The composition with high ultraviolet damage resistance has excellent effects of resisting oxidative damage and inhibiting inflammatory factors, and can achieve the effects of repairing skin barriers, resisting inflammation, relieving, efficiently promoting repair of after-sun skin and the like.

The utility model relates to a self-adaptive pressure tourniquet which comprises a fixing band body, the unfolding face of the fixing band body is in a sector shape with the upper portion wide and the lower portion narrow, rope drawing grooves are formed in the upper end and the lower end of the fixing band body along the edges, corresponding drawing ropes are arranged in the rope drawing grooves, and the other ends of the drawing ropes are movably connected with contraction blocks. The upper end of the side, attached to the skin, of the fixing band body is fixedly connected with a first air bag, the lower end of the side, attached to the skin, of the fixing band body is fixedly connected with a second air bag, and the fan-shaped tourniquet with the wide upper portion and the narrow lower portion can better adapt to differences of limb shapes and sizes of different patients; according to the tourniquet, the fixing band body is arranged, the attaching degree of the fixing band body and the limb is further adjusted through the drawing rope, the tourniquet can be tightly attached to the limb parts with different thicknesses, the multiple air bags can distribute pressure more evenly, and the risk of tissue ischemia and even necrosis caused by uneven pressure is reduced.

The invention relates to the technical field of medical cosmetology, and particularly discloses a dialdehyde group-containing oxidized polysaccharide-water-soluble chitosan hydrogel for cosmetic injection, which comprises the following raw materials: a water-soluble chitosan aqueous solution and a dialdehyde group-containing oxidized polysaccharide aqueous solution, the water-soluble chitosan comprises one of carboxyl alkyl chitosan, hydroxyalkyl chitosan, carboxyl alkyl chitosan sodium salt and hydroxyalkyl chitosan sodium salt. The used raw materials do not contain cross-linking agents, safety risks caused by the fact that the cross-linking agents remain in the body are avoided, and the hydrogel is used for filling wrinkles, improving facial contours and promoting regeneration and repair of skin, so that the skin looks young and smooth.

The invention discloses an application of core proteoglycan or a coding gene thereof as a target spot in preparation of psoriasis treatment drugs, and a series of experiments prove that DCN can effectively protect mouse psoriasis-like dermatitis induced by imiquimod, improve skin scale, erythema, thickening and epidermal abnormal differentiation, enhance the barrier function of skin, improve the curative effect of psoriasis, and improve the curative effect of psoriasis. A large amount of infiltration of inflammatory cells is reduced, and a certain anti-inflammatory effect is achieved. Experimental research shows that the DCN has an obvious drug effect on a psoriasis model, is safe and efficient, has no side effect, is simple in production process and has the potential of realizing medical transformation. And the potential application value of the DCN on other various skin inflammatory diseases can be expanded.

The invention discloses an oil-control composition for whitening and removing acnes. The oil-control composition comprises a raspberry extract, a mangnolia officinalis extract and a natural active matter, the weight ratio of the raspberry extract to the mangnolia officinalis extract to the natural active matter is (0.1-1): (1-5): 1. According to the invention, the raspberry ketone, the magnolia bark extract and the natural active matters are combined, so that the exuberant grease secretion of skin can be fundamentally improved, and inflammation and acne of the skin can be inhibited. Under the optimal weight ratio, the oil can be controlled for a long time, the oil secretion is effectively regulated, the pores are refined, the acne breeding is prevented, and the skin is smoother and finer. The problems that part of current oil control raw materials treat the symptoms but not the root causes, the oil control effect is not lasting, and part of raw materials cause skin thinning and drying and have large irritation to the skin can be solved.

The invention discloses an adapalene external preparation and a preparation method thereof, and relates to the technical field of adapalene preparation preparation. The adapalene gel comprises the following raw materials in percentage by mass: 4.5-7.5% of adapalene, 3.5-8% of a gel base material, 2-4.5% of cellulose, 0.5-2% of a penetration enhancer, 18-25% of a water-retaining agent, 2-5% of a surfactant, a pH value regulator and the balance of water, the dosage of the pH value regulator is based on the standard that the pH value of the adapalene external preparation is regulated to 7-7.5; the gel base material comprises poloxamer or carbomer, and further comprises sa-hao seed gum, and the use amount of the sa-hao seed gum accounts for 25-35% of the total mass of the gel base material. According to the adapalene external preparation provided by the invention, the irritation of adapalene to the skin is basically eliminated by utilizing the effects of the gel base material consisting of poloxamer or carbomer and sa-hao seed gum and the surfactant; the adhesive has good cohesiveness and water-retaining property, can keep the affected part moist after being smeared, promotes medicine absorption, and avoids being wiped off or automatically falling off; the stability is improved, and the medicine slow release time is indirectly prolonged.

The invention relates to the technical field of medical instruments, in particular to a portable leading-in instrument which comprises a shell, a sleeve and a protruding block are arranged on the upper side of the shell in a matched mode, a butt-joint sleeve is coaxially, correspondingly and detachably fixed to the top of the sleeve, a reciprocating rod is slidably connected into the butt-joint sleeve, and a disc block is coaxially fixed to one end of the reciprocating rod. A plurality of micro needle tubes are arranged at the end, away from the reciprocating rod, of the disc block, a liquid storage structure used for supplying liquid to the micro needle tubes is arranged at the other end of the reciprocating rod, a driving structure used for driving the reciprocating rod to reciprocate is arranged in the sleeve, and an air blowing drying structure is further arranged on the shell. According to the device, the effect of guiding liquid medicine into the skin after skin breaking can be achieved, the accurate and uniform liquid medicine guiding effect is achieved, meanwhile, air blowing and skin drying operation can be conducted on the skin with many skin hairs, and the whole device is convenient to operate and convenient to carry.

The present invention relates generally to methods and compositions for treating the skin of a subject. In some embodiments, the methods and compositions disclosed herein include topical or oral administration of a nutraceutical composition and / or topical composition wherein the composition comprises at least two of puerarin, collagen, and hyaluronic acid.

The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.

The invention relates to artificial skin, in particular to self-generating full-layer artificial skin for wound treatment and application of the self-generating full-layer artificial skin. The artificial epidermis has an epidermis-dermis structure similar to skin, and the artificial epidermis structure is composed of an electrostatic spinning nano-film with piezoelectric capacity and has the functions of sterilization, protection and bioelectricity generation of an epidermis layer; the artificial dermal structure is composed of a photo-crosslinking polysaccharide and enzyme crosslinking protein interpenetrating hydrogel skeleton, by adding bioactive components and loading living cells, the effects of releasing active components and cytokines, remodeling wound extracellular matrix and promoting cell proliferation are achieved, and finally healing of acute and chronic wounds is remarkably accelerated. The invention provides a simple, feasible, economical and effective treatment method for sealing a large-area wound, sterilizing the wound and promoting healing of the wound.

The invention discloses a bionic skin structure capable of generating a natural deformation effect. The bionic skin structure comprises bionic skin, a groove is formed in the back surface of the bionic skin; and / or a hard material is arranged on the back surface of the bionic skin or inside the bionic skin, and the hardness of the hard material is higher than that of the bionic skin; and / or a soft material is arranged on the back surface of the bionic skin or inside the bionic skin, and the hardness of the soft material is lower than that of the bionic skin; and / or the back surface of the bionic skin or the interior of the bionic skin is provided with a reinforcing material, and the reinforcing material is used for improving the tear resistance of the bionic skin; and / or the back surface of the bionic skin is provided with connecting points, and the connecting points are used for connecting attachment points on bones or bionic muscles. According to the scheme, the bionic skin can effectively and controllably generate the effects of specific wrinkles, traction and the like, the deformation effect is natural, simulated and more vivid, and therefore the man-machine interaction effect can be further improved.

The invention relates to the technical field of cosmetics, in particular to a product containing flexible glucan, which can be prepared by treating materials containing glucan by adopting high-pressure microjet. According to the product containing the flexible dextran, the flexible dextran has a special intramolecular and intermolecular arrangement mode, has excellent effects of promoting wound healing and resisting inflammation, has an outstanding effect of promoting skin repair after being added into cosmetics, can effectively improve the after-healing effect of dot matrix laser, acid brushing, microneedle and other medical beauty projects, and has a good application prospect. Meanwhile, the repair of sensitive skin can be promoted. According to the preparation method of the product containing the flexible glucan, the intramolecular and intermolecular arrangement form of the glucan can be adjusted, the flexibility of the product is improved, meanwhile, the room-temperature stability of the product is improved, and the product can be massively added into cosmetics.

The present invention relates to the field of biomaterials, specifically a collagen material comprising recombinant humanized collagen type 21 (ColpepA1 21) and its application in facial augmentation. This invention utilizes collagen to not only provide an effective solution to skin aging but also promotes the natural synthesis of collagen within the skin, optimizing skin hydration and barrier function, and enhancing the skin's self-repair capacity. The resulting collagen material is a facial augmentation material. Through local injection or external application, it rapidly smoothes and firms the facial skin, while also improving overall skin health with long-term use.

The invention discloses an essence composition containing lipidosome with an acne removing effect as well as a preparation method and application of the essence composition. The essence composition comprises the following components: 2-30% of lipidosome with the acne removing effect, 0.5-15% of a skin conditioner, 5-40% of a humectant, 0.1-3% of a preservative, 0.15-10% of a thickening agent, 0.05-5% of a chelating agent, 0.01-3% of a pH regulator and deionized water. The lipidosome with the acne removing effect is prepared from the following components in percentage by weight: 1.5 to 2.5 percent of white willow bark extract, 0.3 to 0.7 percent of Pinosine, 2 to 4 percent of rhizoma bletillae root extract, 4 to 6 percent of nicotinamide, 0.15 to 0.35 percent of oligopeptide-3, 7 to 12 percent of lecithin and 1 to 2 percent of cholesterol. In the preparation process, the lipidosome with the acne removal effect is reasonably compounded with other auxiliary material matrixes, so that efficient transmission and absorption of active ingredients can be promoted, irritation to skin can be effectively relieved, meanwhile, the overall effect of the essence is enhanced, the essence has mildness and high efficiency, and the high-efficiency requirement of consumers for the acne removal skin care product is met.

It relates to Centella asiatica-derived exosomes, which is useful in the treatment and / or care of skin. In particular, Centella asiatica-derived exosomes is effective in enhancing skin whitening, reducing skin wrinkles, enhancing skin hydration, and improving skin antioxidant capacity.

The disclosure provides negative pressure wound dressings having an island and a suction drape over the island. The island has an absorbent layer and a skin contact layer, with the skin contact layer configured to extend outwardly past the absorbent layer to space out the step down of the drape over the island. The step down of the drape over the extension of the skin contact layer provides a short step down that has been observed to reduce damage to the skin at the juncture of the drape and the skin.

The invention discloses a tumor radiotherapy prognosis prediction simulation method and system based on big data and a medium, and relates to the technical field of tumor radiotherapy prognosis, and the method comprises the following steps: collecting basic physiological information of a tumor patient, and collecting a color image and a temperature image of skin of a radiotherapy part of the tumor patient; skin color feature extraction and skin temperature feature extraction are carried out to obtain skin color feature data and skin temperature feature data; a radiodermatitis prediction model is constructed; performing prediction simulation on the skin of the radiotherapy part of the tumor patient based on the radiodermatitis prediction model, and performing prediction simulation correction to obtain a radiodermatitis prediction result of the tumor patient; the method is used for solving the problem that when an existing tumor radiotherapy prognosis technology is used for predicting and simulating disease development, the risk and time of radiodermatitis of a tumor patient cannot be objectively and accurately predicted and simulated according to physiological characteristics of skin of the tumor patient after radiotherapy.

Methods, devices, and systems for treating a region of interest (ROI) of skin of a subject or patient in need thereof are disclosed. Such a method of treating a ROI, in some embodiments, comprises irradiating a test region (TR) of the skin with a sub-therapeutic dose of electromagnetic radiation or with a series of sub -therapeutic doses, determining a tissue response of the TR, and generating one or more therapeutic dose parameters based at least in part on the tissue response of the TR. In some embodiments, the method further comprises irradiating the ROI with one or more therapeutic doses of electromagnetic radiation in accordance with the one or more therapeutic dose parameters.

The invention relates to the technical field of medical instruments, in particular to a microneedle array device for skin. Comprising a shell, and the array assembly comprises a microneedle assembly and a driving assembly used for driving the microneedle assembly; the guide assembly is used for guiding the movement of the microneedle array; the detection assembly is provided with a high-frequency ultrasonic sensor and used for detecting the skin thickness. The data acquisition module acquires thickness information, and the data analysis module determines the target penetration depth of the microneedle and generates a control instruction according to the thickness information. And the microneedle driving module drives the microneedle to act after receiving the instruction. The penetration feedback module detects the actual penetration depth in real time and judges whether the actual penetration depth reaches the standard or not. And when the penetration is unqualified, the strategy regulation and control unit adjusts the driving strategy according to the deviation direction between the actual depth and the target depth, so that accurate and controllable micro-needle penetration is realized. The problems that medicine liquid cannot be effectively injected according to different skin thicknesses, and whether potential safety hazards exist in the actual penetration depth of the skin or not cannot be found in time are solved.

The invention discloses a skin anti-wrinkle whitening composition containing ginkgetin and a preparation method of the skin anti-wrinkle whitening composition. The composition takes ginkgo biflavone as a main active component, has the characteristics of safety and effectiveness, can remarkably improve skin elasticity and reduce wrinkles, and has the effect of whitening skin.

The invention discloses a composition for delaying cell senescence, and the composition for delaying cell senescence comprises fisetin, urolithin A and ergothioneine, or consists of fisetin, urolithin A and ergothioneine. The invention also discloses an application of the composition for delaying cell aging in preparation of a product for delaying skin fibroblast aging, and an anti-aging preparation containing the composition. According to the composition for delaying cell aging, fisetin, urolithin A and ergothioneine contained in the composition can generate a synergistic effect, aging of skin fibroblasts can be remarkably delayed, and healing and repairing of skin are promoted.

The invention relates to the technical field of medical auxiliary instruments, and particularly discloses an infusion port pressure sore prevention fixing device which comprises an injection fixing cover, a normal saline arc storage frame is fixedly connected to the outer side of the bottom end of the injection fixing cover, and a pressure sore prevention nursing arc frame is fixedly connected to the outer end of the normal saline arc storage frame; after the infusion port injection fixing cover is installed stably, a butt joint pressing plate is pressed to enable a lifting conduction arc plate to move downwards in a pressure sore prevention nursing arc frame, and normal saline in a normal saline arc storage frame flows into a hook-and-loop fastener cleaning and wiping cotton cushion through a normal saline seepage hole to be absorbed by the hook-and-loop fastener cleaning and wiping cotton cushion; the hook-and-loop fastener cleaning and wiping cotton pad cleans the skin outside the infusion port implantation position of a patient, the pressure sore risk caused by long-time pressing of the skin is reduced, the hook-and-loop fastener cleaning and wiping cotton pad wipes normal saline on the skin of the affected part to reduce friction and stimulation to the skin, the comfort of the patient is improved, meanwhile, the occurrence rate of pressure sores is further reduced, and the use safety of the patient is improved. The risk of cross infection is reduced by automatic delivery of normal saline.