181 results about "Centella asiatica extract" patented technology

The invention belongs to the technical field of cosmetics, and particularly relates to essence with anti-wrinkle, repairing and skin-brightening effects as well as a preparation method and application of the essence. The essence is prepared from the following components in parts by weight: 10 to 70 parts of herba centellae extract, 0.0015 to 0.04 part of crocus sativus extract, 0.5 to 2.5 parts of spirulina maxima extract, 0.015 to 0.2 part of radix gentianae extract, 0.1 to 1.5 parts of panthenol, 0.25 to 1.5 parts of leuconostoc / radish root fermentation product filtrate, 0.1 to 1.5 parts of carnosine and 0.21 to 5.3 parts of anti-wrinkle components. According to the essence, various effective components such as the centella asiatica extract, the spirulina maxima extract and the radix gentianae extract are matched for use, a unique composite formula is formed, all the components promote one another, the anti-wrinkle, repairing and skin brightening effects of the essence can be remarkably enhanced, and therefore all-around skin care is provided for consumers, and the essence has a good market prospect. The overall quality of the skin can be effectively improved.

The invention discloses a preparation method and permeation promotion application of a high-purity sponge bone needle, and belongs to the technical field of sponge bone needles. Comprising the following steps: cutting a natural sponge into pieces, soaking in deionized water, carrying out ultrasonic oscillation, filtering, and cleaning to obtain a pretreated sponge; carrying out enzymolysis on the pretreated sponge with alkaline protease to obtain a primary zymolyte; and carrying out enzymolysis with ginger protease to obtain a secondary enzymolysis product, and carrying out vacuum freeze drying to obtain the high-purity sponge spicule. The natural sponge is subjected to enzymolysis treatment through alkaline protease and ginger protease, and the high-purity sponge spicule is obtained; wheat oligopeptide is grafted on the surface of a sponge spicule, and giant salamander skin collagen, a pomegranate seed extract, a lonicerae flos extract, a centella asiatica extract, an early celery extract, an iris tectorum extract, an oyster shell extract and calcium chloride mixed treatment materials are loaded, so that the repairing effect on skin inflammation acne is improved.

The invention relates to the technical field of cosmetics, in particular to a nanoscale repair composition, a nanoscale repair cosmetic and a preparation method and application of the nanoscale repair composition and the nanoscale repair cosmetic. The invention discloses a nanoscale repairing composition. The traditional Chinese medicine composition is prepared from the following raw material components in parts by weight: 4 to 6 parts of herba centellae extract, 2 to 4 parts of chamomile extract, 2 to 4 parts of radix ginseng extract, 1 to 3 parts of rhizoma curcumae longae extract, 3 to 5 parts of aloe extract, 1 to 3 parts of oat extract, 1 to 2 parts of liquorice root extract, 0.3 to 0.7 part of green tea extract, 0.5 to 1.5 parts of radix salviae miltiorrhizae extract, 0.5 to 1.5 parts of radix angelicae sinensis extract and 0.5 to 1.5 parts of ganoderma atrum extract. , 0.5 to 1.5 parts of radix astragali seu hedysari extract, 0.3 to 0.7 part of rhizoma polygoni cuspidati extract, and 0.3 to 0.7 part of onion extract. The nanoscale repairing composition and the nanoscale repairing cosmetic disclosed by the invention can improve the moisture content of skin, reduce moisture loss and redness of the skin, accelerate healing of injured skin, effectively relieve inflammatory response and promote collagen regeneration of the skin.

The invention relates to application of a medicinal plant synergistic repair technology in functional cosmetics. The functional cosmetics comprise the following components in percentage by mass: 0.05-3 parts of peony root bark extract; 0.01 to 3 parts of magnolia flower extract; 0.005 to 0.5 part of a radix scutellariae extract; 0.005 to 0.5 part of a centella asiatica extract; the synergistic component is 0.001-2 parts of radix ophiopogonis root extract, and the preferable mass ratio of the peony root bark extract to the magnolia flower extract to the scutellaria baicalensis extract to the centella asiatica extract is (6-10): (2-4): 1: (1-8). All plant components are natural extracts, do not contain harmful chemical components and are suitable for various skin types, especially sensitive skin, and the soothing and repairing effects are greatly improved through the matching design and synergistic effect of the plant extracts. For example, due to the synergistic effect of the peony root bark extract and the radix scutellariae extract in the anti-inflammatory and antibacterial aspects, the relieving effect on external stimulation is enhanced; the permeability of the compound is enhanced by the radix ophiopogonis root extract, so that the effect is more long-acting.

The present invention provides an oil-controlling, anti-inflammatory, and soothing botanical composition, comprising the following raw materials in parts by weight: 3-5 parts of Centella asiatica extract, 1-2 parts of Licorice extract, 2-4 parts of Herba Cynanchifoliae extract, 1-4 parts of Epilobium angustifolium extract, 2-5 parts of Trifolium repens flower extract, 4-6 parts of Lemongrass leaf extract, 7-9 parts of Rosa multiflora root extract, and 0.1-0.5 parts of a vitamin complex. The present invention utilizes reflux extraction, enzymatic hydrolysis, and fermentation techniques to fully extract the active substances in the root. The resulting Rosa multiflora root extract exhibits synergistic effects with the other raw materials, providing excellent oil-controlling, anti-inflammatory, and soothing effects on the skin.

The invention provides a theaflavin composition for treating hypertension as well as a preparation method and application thereof, and relates to the technical field of medicines. The theaflavin composition comprises theaflavin, a celery seed extract, a gastrodia elata extract, a parasitic loranthus extract, a centella asiatica extract, a lotus leaf extract and a licorice extract. Wherein the theaflavin can regulate blood fat, inhibit atherosclerosis and improve the vascular endothelial function; the celery seed extract inhibits the activity of angiotensin converting enzyme, and cooperates with theaflavin to regulate blood pressure; the gastrodia elata extract can calm liver wind and improve cerebral circulation; the loranthus parasiticus extract has the effects of tonifying liver and kidney and regulating water sodium metabolism; the centella asiatica extract can resist inflammation and repair vascular endothelium; the lotus leaf extract can clear heat, promote diuresis, calm the liver and suppress yang; and the licorice extract harmonizes the medicines and resists oxidation. According to the invention, theaflavin is taken as a core, multi-dimensional effects of reducing blood pressure, protecting blood vessels and resisting inflammation and oxidation are realized, and a natural and comprehensive health management scheme is provided for hypertensive patients.

The invention discloses a beautifying essence which comprises the following components in percentage by weight: 1% of bifidus yeast fermentation liquor, 3% of boine, 2% of nicotinamide, 0.3% of gallnut extract, 1% of purslane extract, 0.3% of allantoin, 0.2% of centella asiatica extract, 0.3% of tocopherol extract, 0.5% of aesculus chinensis extract, 2% of vitamin E, 0.05% of xanthan gum, 0.05% of sodium hyaluronate, 0.2% of carbomer, 0.5% of p-hydroxyacetophenone, 0.5% of 1, 2-propylene glycol and the balance of water. The cleaning agent is prepared from, by weight, 0.5% of 1, 2-hexanediol, 5% of glycerin, 4% of PEG / PPG-14 / 7 dimethyl ether, 2.2% of glycosylglycerol, 0.2% of tetrahydroxypropyl ethylenediamine, 3% of polyglycerol-3, 0.05% of PDRN powder and the balance water. Effect evaluation test results show that the beauty essence can inhibit the activity of elastase and increase the content of type I collagen in human primary fibroblasts, so that the firming and anti-wrinkle effects are achieved.

The invention discloses an aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition capable of promoting wound repair and application of the aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition. The composition provided by the invention is obtained by compounding the active ingredients such as the aloe extract, the coptis chinensis extract, the centella asiatica extract, the honeysuckle flower extract and the carboxymethyl chitosan, all the ingredients synergistically play the roles of resisting bacteria, diminishing inflammation, resisting aging, promoting wound repair and moisturizing, and the composition has a remarkable effect. Wherein the aloe extract is prepared by adopting a specific deep eutectic solvent (DES), so that the content of anthraquinone compounds in the aloe extract can be increased, and the effects of bacteriostasis, sterilization, inflammation diminishing, detoxification, moisturizing and wound healing promotion of aloe can be better exerted. Specific extract components and the aloe extract are compounded, so that the effect of the aloe extract can be enhanced, the adopted components are natural, mild, safe and low in irritation, and a basis is provided for preparing more medicine products which are antibacterial, anti-inflammatory, anti-aging, moisturizing and capable of promoting wound repair.

The invention relates to a Kava pepper root extract with soothing, repairing and anti-wrinkle effects as well as a preparation method and application thereof, and belongs to the technical field of biological medicines and cosmetics. According to the method, hydroxypropyl-cyclodextrin and / or sulfobutyl-cyclodextrin are / is used as an extracting agent to fully extract the main functional component kavain in the kava pepper root powder, and a fat-soluble component kavain is clathrated by using the hydrophilicity and clathration effect of hydroxypropyl-cyclodextrin and sulfobutyl-cyclodextrin, so that the extraction efficiency of kavain is improved, and the yield of kavain is increased. The extract which contains the kavain and is soluble in water is obtained. The mixture of polyaluminum chloride and diatomite is used as an impurity removal agent to fully remove unstable components and pigments in the crude extract, and the prepared kavain extract has high purity and extraction rate, and has good solubility in water and good stability. The kava pepper root extract and the centella asiatica extract are combined to achieve a synergistic repairing effect, and the composition can be widely applied to the industries of biological medicine, cosmetics and the like.

The invention discloses a multifunctional face and chest care mask and a preparation method thereof, and belongs to the technical field of beauty and skin care. The mask adopts a split type design, comprises a face membrane and a chest membrane, and realizes six functions of moisturizing, cleaning pores, whitening and brightening, soothing and repairing, controlling oil and removing acnes, and resisting aging and tightening through innovative active component combination and a multi-layer structure. The face membrane comprises an adsorption layer, a slow release layer and a water locking layer; and the chest membrane adopts an elastic fiber substrate and a permeation-promoting microneedle structure, so that the absorption of active ingredients is enhanced. The active ingredients comprise a hyaluronic acid compound, nano-scale bentonite, nicotinamide, a centella asiatica extract, a salicylic acid derivative, collagen polypeptide and the like, and the comprehensive nursing effect is improved through the synergistic effect. The preparation method is combined with electrostatic spinning, micro-capsule wrapping and 3D printing technologies, and precise controlled release and personalized adaptation are achieved.

The invention belongs to the technical field of skin care products, and discloses a quick-acting red-removing repair product which comprises the following components: water, caprylic / capric triglyceride, glycerol, sorbitol, phosphatidylcholine, 1, 3-propylene glycol, xanthan gum, eicosapentaenoic acid, docosahexaenoic acid, phytosphingosine, centella asiatica extract and tocopheryl acetate. A turmeric rhizome extract and 1, 2-hexanediol. Through mutual cooperation of the turmeric root extract and the centella asiatica extract, by taking enhancement of skin immune regulation and skin barrier functions as an action mechanism, on one hand, skin inflammatory response can be inhibited, and inflammation, microorganisms and bacteria can be effectively resisted, and on the other hand, skin barrier reconstruction can be promoted, wound healing can be promoted, and an ECM matrix can be protected; in addition, the eicosapentaenoic acid, the docosahexaenoic acid, the turmeric root extract, the phytosphingosine and the centella asiatica extract are wrapped by the nano-microcapsule liposome, so that the activity of the product can be ensured.

The invention relates to a composition containing whitening and brightening lipidosome and a preparation method and application thereof, and belongs to the technical field of cosmetics. Glycyrrhiza glabra and centella asiatica extracts are extracted through a compound fermentation technology, the molecular weight of the extracts is reduced to 500-1000 Da through synergistic fermentation of lactic acid bacteria, saccharomycetes and bacillus subtilis, the extracts, lecithin, cholesterol, nicotinamide and the like form lipidosome, and the lipidosome is mixed to obtain the composition containing the whitening and brightening lipidosome. According to the preparation method of the liposome, the stable liposome with the particle size of 100-200nm is formed by combining thin film dispersion with homogenization treatment. After the composition is subjected to illumination storage at 45 DEG C for 60 days, the retention rate of active ingredients is greater than or equal to 90%, the inhibition rate of tyrosinase reaches 85.6%, and the transdermal absorption amount of nicotinamide is increased by 15-20% compared with that of a traditional process. The composition can be used for preparing whitening cosmetics such as essence, and has the advantages of high stability and remarkable effect.

The invention discloses cosmetic oil with whitening, soothing and anti-aging effects and a preparation method of the cosmetic oil. The plant essential oil is prepared from the following raw materials in parts by weight: 0.5 to 1.5 parts of sunflower seed oil, 0.01 to 0.05 part of lupinus albus seed extract, 0.0001 to 0.001 part of tocopherol, 0.01 to 0.05 part of rosemary leaf extract, 0.001 to 0.1 part of dimethyl methoxy benzodihydropyranol, 50 to 90 parts of caprylic / capric triglyceride, 0.01 to 0.2 part of ascorbyl tetraisopalmitate, 0.01 to 0.2 part of bisabolol, 5 to 20 parts of squalane, 2 to 8 parts of simmondsia chinensis seed oil, 5 to 15 parts of meadowfoam seed oil and 0.1 to 1 part of lavender oil. And 0.3-1 part of a centella asiatica extract. According to the cosmetic oil product provided by the invention, by optimizing the use of substances, the composition has triple effects of whitening, relieving and resisting aging, can meet multiple skin care requirements of consumers at the same time, and is wide in market application range.

The invention belongs to the technical field of cosmetics, and particularly relates to a silk fibroin aggregate-based dispersed organic active substance as well as a preparation method and application thereof. The preparation method of the silk fibroin aggregate-based dispersed organic active substance comprises the following steps: (1) dissolving an organic active substance in a first solvent to obtain a first solution; dissolving the silk fibroin aggregate in a second solvent to obtain a second solution; (2) slowly adding the second solution into the first solution, mixing and homogenizing to obtain a silk fibroin aggregate-based dispersed organic active substance; wherein the silk fibroin aggregate is prepared by mixing a silk fibroin aqueous solution and alcohol. The silk fibroin aggregate-based dispersed organic active substance prepared by the preparation method can improve the bioavailability of the organic active substance (such as vitamin C, hyaluronic acid, coenzyme Q10, nicotinamide, arbutin, kojic acid, licorice extract, centella extract, chamomile extract or green tea extract) in cosmetics.

The invention relates to the technical field of health care products, in particular to silver ion polypeptide antibacterial gel. The invention discloses a silver-polypeptide-containing shampoo, which is prepared from the following ingredients including 0.1 to 1 percent of silver ions, 0.5 to 3 percent of polypeptide, 60 to 85 percent of deionized water, 1 to 5 percent of jingnaoji leaf extracts, 1 to 5 percent of herba portulacae extracts, 1 to 5 percent of radix notoginseng extracts, 1 to 5 percent of radix sophorae flavescentis extracts, 1 to 5 percent of saffron crocus extracts, 1 to 5 percent of apple seed extracts, 1 to 5 percent of herba violae extracts, 1 to 5 percent of fructus cnidii extracts, 1 to 5 percent of sunflower extracts, 1 to 5 percent of herba centellae extracts and 0.5 to 3 percent of herba menthae extracts. The preparation method comprises the following steps: extraction preparation, silver ion preparation, mixing and stirring, and gel preparation. The invention has the beneficial effects of scientific and reasonable formula, obvious synergistic effect and strong antibacterial effect; the preparation process is simple and feasible, effective activity of each component can be fully reserved, and stable product quality is guaranteed; the product is mild and non-irritant, is suitable for daily cleaning, health care and health care of private parts, does not destroy normal microbial balance of the private parts, and is high in use safety.

The invention relates to the technical field of cosmetics, and particularly discloses an all-directional anti-acne repairing composition as well as a preparation method and application thereof. The comprehensive anti-acne repairing composition is prepared from the following components in parts by weight: 0.01 to 2 parts of flexible salicylic acid, 0.001 to 2 parts of rhodomyrtus tomentosa fruit extract, 0.001 to 0.5 part of quaternary ammonium salt, 0.01 to 5 parts of nicotinamide, 0.001 to 3 parts of herba centellae extract, 0.01 to 3 parts of phellinus linteus extract, 0.0001 to 2 parts of phaeodactylum tricornutum extract and 0.001 to 2 parts of bio-saccharide gum-1. The comprehensive anti-acne repairing composition provided by the invention can resist acnes comprehensively, achieves the effects of removing aged cutin, controlling oil, sterilizing, resisting inflammation, relieving and fading marks and moisturizing, and has a comprehensive repairing effect on various skin injuries including acne skin.

The invention discloses a composition and a cosmetic with anti-allergy, itching-relieving and redness-removing effects. The composition is prepared from the following raw material components: a herba centellae extract with madecassoside content of not less than 85wt%, a dendrobium officinale stem extract and dihydrooat acyl o-aminobenzoic acid. The composition comprising the three components is added into the cosmetic, so that the cosmetic has good system stability, also has enhanced anti-allergy, itching-relieving and red-removing effects, and can improve skin problems from multiple dimensions.

The invention relates to the technical field of skin care product preparation, and discloses a skin care product preparation method and equipment capable of whitening skin, removing freckles, smoothing skin and preserving moisture, and the skin care product is prepared from the following raw materials in percentage: 30% of tea leaf extract, 15% of oat extract, 15% of rose extract, 20% of centella asiatica extract, 5% of vitamin E, 10% of pearl powder and 5% of chitosan. The skin care product capable of whitening, removing freckles, smoothing skin and preserving moisture can be prepared, in the preparation process, the liquid level of mixed liquid can be moved upwards during stirring, raw materials left on plastic cloth due to liquid level recovery after stirring is stopped are flapped and shaken off into the mixed liquid, full utilization of the raw materials is guaranteed, the preparation effect is improved, and the skin care product can be used for whitening, removing freckles, smoothing skin and preserving moisture during flapping and shaken off. And the flapped raw materials can be blown downwards, so that the raw materials are prevented from flying onto the stirring assembly, and the raw materials are ensured to fully return to the mixed liquid.

The invention discloses snowflake cream with pearly luster and a preparation process of the snowflake cream. The snowflake cream comprises the following raw material components: a phase A: water; butanediol; glycerol; methyl glucitol polyether-20; a polyacrylate cross-linked polymer-6; sodium hyaluronate; potassium hydroxide (90%); 4-hydroxyacetophenone; xanthan gum; phase B: caprylic / capric triglyceride; cetostearyl alcohol; stearic acid; a polydimethylsiloxane; squalane; simmondsia chinensis seed oil; mineral oil; and polyethylene glycol (PEG)-100 stearate. Glyceryl stearate; tocopheryl acetate; isononyl isononanoate; a phase C: 1, 2-hexanediol; carnosine; a centella asiatica extract; collagen; the snowflake cream has the advantages of uniform pearly luster texture and the advantages of traditional snowflake cream.

The invention discloses a traditional Chinese medicine skin chemical stripping reagent and a preparation method thereof. The reagent comprises a saturated potassium hydroxide solution, glutinous rice, gallnut, glycerol and a centella asiatica extract which form a functional formula based on the compatibility principle of monarch, minister, assistant and guide. The preparation method comprises the steps of weighing, crushing, multi-stage stirring, filtering and cooling, closed packaging and the like, and is clear in process parameters and clear in operation path. The reagent is suitable for removing cuticles, the using method comprises dispensing, standing and flushing, the whole stripping process is mild, and the adaptability is high. Compared with traditional tartaric acid and salicylic acid exfoliating agents, the reagent is low in irritation, natural in structure and stable in formula, has the dual functions of exfoliating, repairing and conditioning, is suitable for improving various pigment increase type skin diseases, and has a good treatment effect on lesions located at the positions difficult to operate such as the nose, the lip periphery and the eye periphery. The technical scheme has good safety, ingredient controllability and popularization prospect, and is suitable for being used in the fields of orthopaedic surgery and dermatology department.

The invention discloses an anti-allergy soothing composition as well as a preparation method and cosmetics thereof. The anti-allergy soothing composition is prepared from, by mass, 1%-5% of radix gentianae extract, 1%-4% of radix sophorae flavescentis extract, 1%-3% of herba centellae extract, 2%-6% of calendula extract, 1%-4% of oat bran extract, 2%-5% of paeonia lactiflora root extract, 0.5%-1% of glyceryl polyacrylate and the balance solvent, and the solvent is prepared from water and 1, 3-butanediol in the mass ratio of 5: 5. The formula is matched with a specific preparation method, so that the composition has good stability and anti-allergy and soothing effects.

The invention relates to a skin antiallergic composition and a preparation method and application thereof, and the composition is prepared from the following raw materials: sodium cellulose, essence, propylene glycol, a coating solution, a nonionic surfactant and water, the coating solution is prepared by taking modified chitosan microspheres, ascophyllum nodosum extract, chamomile flower extract, centella asiatica extract, anthemis nobilis flower extract, glycerol and water as raw materials, and the modified chitosan microspheres are products obtained by grafting polylactic acid with chitosan. The modified chitosan microsphere can form a nano-micelle with a core-shell structure in a solvent, the ascophyllum nodosum extract, the chamomilla recutita extract, the centella asiatica extract and the anthemis nobilis extract are wrapped in the nano-micelle, the situation that the extracts are degraded or inactivated due to the external environment is avoided, a stable dispersion system can be formed in water, and the stability of the nano-micelle is improved. The plant extract is released after the body surface is coated, and the plant extract and other components synergistically improve the anti-allergic effect of the skin.

The application belongs to the technical fields of nanobiomaterials and cosmetic efficacy materials, and discloses a centella asiatica-derived carbon dot, a preparation method thereof and application thereof in cosmetics. The preparation method of the centella asiatica-derived carbon dot comprises the following steps: step 1, using centella asiatica extract as a carbon source and urea as a nitrogen source, performing a hydrothermal carbonization reaction to obtain a reaction solution; and step 2, performing ultrafiltration purification and freeze-drying on the reaction solution obtained in step 1 to obtain the centella asiatica-derived carbon dot. The centella asiatica-derived carbon dot can penetrate the stratum corneum to achieve deep delivery to the dermis and form protection to the collagen matrix.

The invention belongs to the field of daily chemicals. The body care composition comprises the following components in percentage by weight: 0.5%-10% of the lemon-bat hairy-leaf extract, 0.5%-10% of the lemon-bat hairy-leaf extract, 0.5%-10% of the lemon-bat hairy-leaf extract and the balance of water. 0.3%-10% of a lens culinaris seed extract; 0.5%-5% of a centella asiatica extract; 0.3%-1.0% of caffeine; 0.2%-1.0% of sodium salicylate; 0.03% to 0.3% of dipotassium glycyrrhizinate; 0.3% to 1.0% of cyclodextrin; 0.3% to 0.9% of capryloyl glycine; 0.3%-10% of a skin conditioner; 30%-50% of a polyol; and the balance of deionized water. The body care composition containing the lemon pekoe leaf extract is applied to the skin care composition, so that the skin barrier can be repaired, the oil-water balance of the skin can be controlled, the water content of the skin can be increased, excessive grease secretion can be reduced, and the skin can be effectively protected.

This invention discloses a composition for relieving allergies, itching, and improving rough skin, its preparation method, and its application. The composition comprises the following active ingredients: asiaticoside, centella asiatica extract, kava extract, aescin, allantoin, and sodium hyaluronate. This invention prepares the composition using raw materials and proportions containing asiaticoside, centella asiatica extract, kava extract, aescin, allantoin, and sodium hyaluronate. The synergistic effect between these components results in excellent anti-allergic, anti-itch, and skin-roughening effects. After preparing the composition into a soothing and anti-itch cream, tests showed that it significantly reduced the a* value and lactic acid stinging score of sensitive skin. Doctor evaluation methods further confirmed its significant improvement effects on burning, erythema, swelling, peeling, stinging, and itching of sensitive skin, while also showing a significant effect on improving rough skin.

The invention relates to the field of pet food, in particular to a traditional Chinese medicine composition, a preparation method thereof and application of the traditional Chinese medicine composition in pet oral care. The invention discloses a traditional Chinese medicine food additive for dog oral care. The traditional Chinese medicines are medicinal and edible traditional Chinese medicines and comprise centella asiatica extract, mint extract and aloe extract. The components act together and are integrally suitable for dog oral care. Efficacy tests prove that the dog oral care solution can effectively promote dog oral health, inhibit dog oral saliva colonies, reduce the hydrogen sulfide content in dog oral cavities, relieve ozostomia, maintain fresh breath, reduce the risk of dog oral diseases and realize the comprehensive effect of dog oral care. The traditional Chinese medicine additive is good in palatability and high in acceptability of pets, can be directly eaten, can also be sprayed on dog food to prepare dog food with an oral care effect, and has high application value.

The invention discloses a moisturizing and soothing fermentation composition as well as a preparation method and application thereof. The preparation method of the moisturizing and soothing fermentation composition comprises the following steps: (1) inoculating a fermentation substrate containing centella asiatica and paeonia lactiflora with a seed solution of hirsutella asiatica for fermentation so as to obtain a crude fermentation solution; and (2) carrying out heating treatment and filtering treatment on the crude fermentation liquid to obtain the moisturizing and soothing fermentation composition. The moisturizing and soothing fermentation composition prepared by the invention adopts a mode of extracting and preparing multiple components at the same time, a galactose yeast-like bacterium fermentation product filtrate is prepared, and the moisturizing and soothing fermentation composition also contains a centella asiatica extract and a Chinese herbaceous peony extract; the composition can promote the expression of a paphiopedilum A protein gene, reduce the expression of an IL-6 gene and inhibit zebra fish neutrophile granulocyte aggregation; the moisturizing and soothing effects can be shown from multiple angles.

The present invention relates to a composition for anti-inflammatory, skin whitening, and skin regeneration comprising a mixture of hemp seed oil, Artemisia annua extract, and Centella asiatica extract as an active ingredient. Since the mixture of hemp seed oil, Artemisia annua extract, and Centella asiatica extract of the present invention has excellent effects in significantly improving anti-inflammatory activity, melanin production inhibitory activity, and skin cell regeneration efficacy compared to hemp seed oil, Artemisia annua, and Centella asiatica extracts alone, it can be usefully used as a functional cosmetic or health functional food for anti-inflammatory, skin whitening, and skin regeneration, or as a treatment for skin pigmentation disorders.

The invention discloses a composition with a skin barrier repairing effect as well as a preparation method and application thereof. The composition comprises carboxymethyl chitosan, ceramide and a centella asiatica extract, the mass ratio of the carboxymethyl chitosan to the ceramide to the centella asiatica extract is (0.01-5): (0.01-5): (0.01-5). The centella asiatica extract comprises one or a combination of more of madecassic acid, a centella asiatica root extract, asiaticoside and madecassoside, and the ceramide comprises one or a combination of more of ceramide NP, ceramide EOP, ceramide AS, ceramide AP, ceramide NS and ceramide NG. By implementing the invention, the skin barrier can be effectively repaired, the sensitivity can be relieved, and the moisturizing and nourishing effects can be realized.

The invention relates to the technical field of medical preparations or cosmetics, in particular to the technical field of preparation of plant-derived active ingredients in the medical preparations or cosmetics, and discloses a preparation process of a centella asiatica extract, which comprises the following steps: extracting centella asiatica to obtain a centella asiatica concentrated product from centella asiatica by adopting an enzyme-assisted hot ethanol extraction method in combination with a resin purification technology; the preparation method comprises the following steps: preparing centella asiatica extract molecularly imprinted polymer resin, filling a solid-phase extraction empty column with the centella asiatica extract molecularly imprinted polymer resin to prepare a resin column, and purifying a centella asiatica concentrated product through the resin column to prepare the centella asiatica extract with the purity as high as 99%. The centella asiatica extract prepared by the invention has repairing and soothing effects, can be used as an active ingredient in medical preparations or cosmetics, is used for preparing a gel preparation for treating skin injury, or is added into a repairing skin care product, and realizes the combination of a medical-grade skin care effect and daily care by promoting skin barrier repairing and soothing damaged parts.