41 results about "POMEGRANATE SEED" patented technology

The invention discloses a preparation method and permeation promotion application of a high-purity sponge bone needle, and belongs to the technical field of sponge bone needles. Comprising the following steps: cutting a natural sponge into pieces, soaking in deionized water, carrying out ultrasonic oscillation, filtering, and cleaning to obtain a pretreated sponge; carrying out enzymolysis on the pretreated sponge with alkaline protease to obtain a primary zymolyte; and carrying out enzymolysis with ginger protease to obtain a secondary enzymolysis product, and carrying out vacuum freeze drying to obtain the high-purity sponge spicule. The natural sponge is subjected to enzymolysis treatment through alkaline protease and ginger protease, and the high-purity sponge spicule is obtained; wheat oligopeptide is grafted on the surface of a sponge spicule, and giant salamander skin collagen, a pomegranate seed extract, a lonicerae flos extract, a centella asiatica extract, an early celery extract, an iris tectorum extract, an oyster shell extract and calcium chloride mixed treatment materials are loaded, so that the repairing effect on skin inflammation acne is improved.

This invention discloses a pesticide composition containing silicon-rich rings and its application in controlling banana leaf spot disease, belonging to the field of biocide pesticide technology. The invention extracts pomegranate seeds. In indoor experiments, the colony diameter of *Curvularia natans* leaf spot pathogen was reduced, indicating that the pomegranate seed extract can inhibit the growth of *Curvularia natans*. Using this extract and silicon-rich rings as synergistic components, it is combined with propiconazole to prepare a pesticide composition containing silicon-rich rings. In field trials, the disease index of the plants decreased, indicating that *Curvularia natans* leaf spot pathogen was inhibited; the complex group showed the highest relative control efficacy, reaching 78.13%. The pesticide composition containing silicon-rich rings prepared by this invention can better inhibit *Curvularia natans* leaf spot pathogen and is suitable for pesticide development for controlling banana leaf spot disease.

This invention discloses a composition for enhancing immunity through gut microbiota, its preparation method, and its application. The composition comprises the following raw materials: a complex prebiotic, polyphenols, inactivated *Saccharomyces boulardii*, and plant extracts. The complex prebiotic includes human milk oligosaccharides and arabinogalactan, the polyphenols include berry polyphenols and grape polyphenols, and the plant extracts include pomegranate seed extract and kale extract. This invention's composition, on the one hand, selectively enriches *A. AKK* bacteria through prebiotics; *A. AKK* can directly interact with various immune cells to enhance immunity. On the other hand, supplementing with yeast factors can also inhibit inflammation and enhance immune responses, thereby significantly increasing the number of *A. AKK* bacteria in the gut microbiota and simultaneously improving intestinal cellular immune function.

The invention discloses a method for efficiently preparing spray-dried pomegranate fruit powder, which comprises the following steps: separating pomegranate seeds and peel, drying and grinding the peel, and extracting water-soluble pectin; the preparation method comprises the following steps: juicing pomegranate seeds, filtering to obtain pomegranate juice, dividing the pomegranate juice into three parts A, B and C according to a mass ratio of 3: 1: 1, respectively adding a sodium citrate buffer solution with the pH value of 5.0, maltodextrin, rosmarinic acid and beta-cyclodextrin into the part A, adding an acetic acid solution with the pH value of 3.0 and chitosan into the part B, adding deionized water with the temperature of 40 DEG C, water-soluble pectin and nano silicon dioxide into the part C, sequentially adding the part B and the part C into the part A, standing, and filtering to obtain the pomegranate juice. And adding ethanol and xanthan gum, mixing, carrying out high-pressure homogenization treatment, and finally, carrying out spray drying to obtain the pomegranate fruit powder. The spray drying technology is adopted for drying, the nutritional ingredients of the prepared pomegranate fruit powder are well reserved, the pomegranate fruit powder is bright in color and luster and fine and smooth in taste, and the pomegranate fruit powder has wide application prospects and development potential.

The purpose of the present invention is to provide a composition having an action of inhibiting the androgen receptor (AR) pathway activity, and the present invention aims to effectively utilize discarded pomegranate seeds and add value thereto.　A pharmaceutical composition for inhibiting the androgen receptor (AR) pathway activity according to the present invention is characterized by containing a pomegranate seed extract. Furthermore, a preferred embodiment of the pharmaceutical composition for inhibiting the androgen receptor (AR) pathway activity according to the present invention is characterized in that the inhibition of the androgen receptor (AR) pathway activity is due to the inhibition of the transcription activity of the androgen receptor (AR). Furthermore, a preferred embodiment of the pharmaceutical composition for inhibiting the androgen receptor (AR) pathway activity according to the present invention is characterized in that the inhibition of the androgen receptor (AR) pathway activity is due to the inhibition of the androgen receptor (AR) protein expression.

The invention belongs to the technical field of compound preparation, and particularly discloses a pomegranate seed oil supercritical extraction method and application in prevention and treatment of non-alcoholic fatty liver disease, and the method comprises the following steps: S1, crushing dried pomegranate seed medicinal materials, screening 18-60-mesh parts, and carrying out CO2 supercritical extraction by adopting four-factor three-level experimental design to obtain the pomegranate seed oil; the corresponding pomegranate seed oil is prepared through combined extraction under different process conditions. S2, performing methyl esterification treatment on the pomegranate seed oil, and determining the contents of three main components, namely punicic acid, linoleic acid and oleic acid, of the pomegranate seed oil by adopting GC-FID (Gas Chromatography-Flame Ionization Detector); and S3, calculating the total content and the oil yield of the three main components, and performing multi-objective optimization on supercritical extraction process parameters through an entropy weight method by taking the total content and the oil yield as comprehensive indexes.

The present invention provides a hydrolyzed polypeptide, a preparation method and an application thereof, relating to the field of biotechnology. For the first time, the present invention separates and purifies a short peptide with antioxidant activity from pomegranate seeds by using a composite enzymolysis technology. Through antioxidant activity identification, the active short peptide has good free radical scavenging activity, can effectively scavenge residual DPPH free radicals and ABTS free radicals in the body, and has great application prospects.

The invention discloses a sleep-aiding pomegranate wine. The pomegranate juice wine is prepared from the following components through three times of gradient fermentation and blending: pomegranate juice primary fermented wine with the volume ratio of 60 + / -2%, the alcoholic strength of 8-9% vol and the fermentation temperature of 1-3 DEG C; the pomegranate rind processing wine has a volume ratio of 10 + / -1%, the pomegranate rind is processed by a traditional Chinese medicine processing technology, and then low-temperature extraction is carried out at an extraction temperature of less than or equal to 50 DEG C; flavonoid compounds (such as quercetin and kaempferol) in pomegranate seeds can inhibit the activity of epoxidase-2 (COX-2) and reduce the release of inflammatory factors such as prostaglandin E2 (PGE2) (experimental data: the inhibition rate is greater than or equal to 65%); vitamin C and polyphenol cooperate to promote joint synovial cells to secrete hyaluronic acid, the viscoelasticity of the joint lubricating fluid is improved (the viscosity is increased by 30%), and the pain of osteoarthritis is relieved.

The utility model discloses an extrusion device for processing pomegranate seeds, which comprises a base, the top of the base is fixedly connected with a support plate, the top of the support plate is provided with a driving mechanism, the two sides of the support plate are hinged with semicircular baffles, the base is hinged with two first hydraulic cylinders, and the two first hydraulic cylinders are hinged with two second hydraulic cylinders. The movable end of the first hydraulic cylinder is hinged to the outer side of the semicircular baffle, and a cavity is formed in the supporting plate. According to the juicer, juice flows into the cavity after being filtered by the filter screen plate and then is discharged through the liquid discharging head in the strip-shaped groove, juice discharging is achieved, after juicing is completed, the two first hydraulic cylinders are started to drive the two semi-circular baffles to be unfolded outwards, the two semi-circular spaces are opened, and the two semi-circular baffles are separated from each other. And then internal residual solid residues are conveniently and rapidly cleaned, so that the device has the advantages that the juicing space can be rapidly opened for cleaning after juicing, the cleaning effect is improved, and the juicing efficiency is improved.

The invention belongs to the technical field of natural anti-corrosion materials, and provides a natural anti-corrosion composition containing cinnamon bark extract and a preparation method and application of the natural anti-corrosion composition. The natural preservative composition provided by the invention comprises a cinnamon bark extract and a synergistic compound, the synergistic compound comprises a mangnolia officinalis bark extract, a perilla leaf extract, a rhizoma atractylodis root extract, a folium artemisiae argyi extract, a wrinkled gianthyssop herb extract, a radix ophiopogonis root extract, a pomegranate seed extract, a pomelo extract, a thyme leaf extract, a calendula extract, a hyperforin perforatum extract, a melaleuca alternifolia leaf extract, a ginger root extract and an eucalyptus globulus leaf extract; the mass content of cinnamyl aldehyde in the cinnamon bark extract is less than or equal to 20wt%, and the antibacterial composition has the advantages of broad-spectrum bacteriostasis, high stability, difficulty in discoloration and precipitation, acid and alkali resistance, high temperature resistance, safety and small irritation. The antibacterial composition is prepared from at least one of a ginseng root extract, a rosemary leaf extract, a papaya fruit extract, a chamomile flower extract, a soybean seed extract and a wheat bran extract, and the mass content of cinnamyl aldehyde in the cinnamon bark extract is less than or equal to 20wt%.

The invention discloses an anti-aging, anti-wrinkle and anti-tumor Chinese yam polysaccharide composition and a preparation method thereof. The composition comprises the following components in parts by mass: 30-80 parts of Chinese yam polysaccharide, 10-50 parts of stachyose, 5-25 parts of pomegranate seed extract, 5-20 parts of grape seed extract, 3-15 parts of blueberry extract, 2-12 parts of tea polyphenol, 1-10 parts of sea cucumber peptide and 1-10 parts of soybean peptide (with the molecular weight of 300-1000Da). Preferably, 0.5-5 parts of resveratrol (the purity is greater than or equal to 98%) and 3-20 parts of acerola cherry powder (VC is greater than or equal to 15%) are added. The preparation method comprises the following steps: dissolving polysaccharides and saccharides, adding the extract, homogenizing, adjusting the pH value to 6.0-7.0, carrying out enzymolysis by using compound protease at 35-40 DEG C, and finally carrying out spray drying. Experiments show that the composition has a synergistic effect in the aspects of resisting saccharification (the highest inhibition rate reaches 78.5%), resisting oxidation (the DPPH clearance rate is 91.3%), increasing the content of hydroxyproline in skin (+ 74.1%), inhibiting tumor cell proliferation (62.5%) and improving ultraviolet wrinkles (the score is reduced by 61%).

The application discloses a pomegranate ferment with the effects of firming, anti-wrinkle and soothing and repairing, and a preparation method and application thereof, and belongs to the technical field of cosmetic raw materials. A high-activity pomegranate ferment is obtained by yeast and lactic acid bacteria synergistic fermentation with pomegranate by-products (pomegranate peel and pomegranate seeds) as raw materials. The yeast-lactic acid bacteria combined fermentation of pomegranate seeds / peel has the effects of synergistically improving the release and biological transformation of active ingredients, significantly enhancing the antioxidant and functional activity, realizing zero waste high value and resource full utilization, improving the odor and eliminating the adverse characteristics, and the like, so that the pomegranate ferment can be used for preparing a cosmetic with the effects of antioxidant, anti-inflammatory, anti-wrinkle and soothing and barrier repair.

This invention belongs to the field of traditional Chinese medicine (TCM) technology, specifically relating to a TCM composition with detoxifying and uterus-warming effects and its application in the preparation of external products. The medicinal component of this external TCM product is composed of fenugreek, amethyst, rose, pomegranate seed, centella asiatica, long pepper, five-finger peach, lycopodium, litchi seed, and achyranthes bidentata. Animal experiments show that this product can significantly reduce the number of writhing movements in animals with cold-induced blood stasis type dysmenorrhea, lower COX-2 and PGE2 levels in the uterus, and improve peritoneal inflammation, demonstrating good detoxifying, blood stasis-removing, menstruation-regulating, and pain-relieving effects. Regarding blood rheology, it exhibits the effects of inhibiting platelet aggregation, dilating blood vessels, reducing blood viscosity, and balancing TXA2 and PGI2 levels, reflecting its effects of warming the kidneys and uterus, and strengthening the body's foundation. In summary, the TCM composition of this invention and its prepared external product can warm the kidneys and uterus, promote diuresis and eliminate turbidity, providing a novel TCM external application solution for the clinical treatment of cold-induced blood stasis type dysmenorrhea.

The present invention relates to an optimal packaging method for enhancing quality characteristics and extending the expiration date of fresh-cut pomegranate, and a fresh-cut pomegranate fresh convenience food produced thereby. More specifically, the present invention relates to an oxygen transmission rate (OTR) film for loose pomegranate seeds, a packaging system for loose pomegranate seeds, and a method for maintaining the freshness of loose pomegranate seeds, the OTR film having an oxygen transmission rate of 10,000 cc / m-2 / day-1 / atm-1 to 100,000 cc / m-2 / day-1 / atm-1. The OTR film for loose pomegranate seeds, according to the present invention, enables stably maintaining the oxygen concentration, carbon dioxide concentration, Brix, and pH of pomegranate, and may have the effects of inhibiting microbial growth and suppressing the occurrence of off-flavors.

The purpose of the present invention is to provide a composition having an inhibitory action on the proliferation of hormone-dependent cells in order to make effective use of and add value to pomegranate seeds to be discarded.　A pharmaceutical composition for inhibiting the proliferation of hormone-dependent cells according to the present invention is characterized by containing pomegranate seed extract. A preferred embodiment of the pharmaceutical composition for inhibiting the proliferation of hormone-dependent cells according to the present invention is characterized in that the hormone-dependent cells are prostate cells. A preferred embodiment of the pharmaceutical composition for inhibiting the proliferation of hormone-dependent cells according to the present invention is characterized in that the prostate cells are androgen-dependent or independent cells.

The invention discloses a Mongolian medicine characteristic enema for treating ulcerative colitis, and relates to the technical field of biological medicine. Raw materials of the enema comprise a Mongolian medicine composition. The Mongolian medicine composition is prepared from the following components in parts by weight: 25 to 35 parts of pomegranate seeds, 15 to 25 parts of cortex cinnamomi, 15 to 25 parts of gypsum rubrum, 15 to 25 parts of fructus amomi rotundus, 15 to 25 parts of fructus forsythiae, 15 to 25 parts of rhizoma curcumae longae, 15 to 25 parts of fructus chebulae, 15 to 25 parts of rhizoma zingiberis, 15 to 25 parts of puffball, 15 to 25 parts of caulis clematidis armandii, 5 to 15 parts of radix glycyrrhizae preparata, 5 to 15 parts of cacumen biotae, 5 to 15 parts of long pepper, 5 to 15 parts of alkali and 5 to 15 parts of rhizoma polygonati. The Mongolian medicine characteristic enema developed by the invention has remarkable technical advantages in the aspect of treating ulcerative colitis, including improvement of the local action effect of the medicine, reduction of untoward effects, definite clinical curative effect and innovative Mongolian medicine characteristics, and a safe, effective and economic treatment scheme can be provided for UC (ulcerative colitis) patients.

The invention discloses a preparation method of a pomegranate seed oil and polyphenol loaded co-loaded nanoemulsion, which comprises the following steps: compounding an emulsifier CO40 and Span80 to obtain a mixed emulsifier for later use; adding propylene glycol serving as a co-emulsifier into the mixed emulsifier, and uniformly mixing to obtain a mixed surfactant for later use; uniformly mixing the mixed surfactant and the pomegranate seed oil to obtain a mixture for later use; and adding a pomegranate seed polyphenol aqueous solution into the mixture, and carrying out microjet high-pressure homogenization to obtain the pomegranate seed oil and polyphenol loaded co-loaded nanoemulsion. The co-loaded nano-emulsion prepared by the invention presents a uniform nano-dispersion system and is clear and transparent. An in-vitro stability experiment shows that the co-loaded nanoemulsion can be stably stored within 30 days at 25 DEG C, and a layering phenomenon does not occur. The antioxidant capacities of the co-loaded nanoemulsion, the pomegranate seed polyphenol nanoemulsion and the pomegranate seed oil nanoemulsion are compared by using a DPPH free radical scavenging capacity method, and the result shows that the antioxidant capacity of the co-loaded nanoemulsion is remarkably enhanced under the same concentration.

The utility model discloses a pomegranate seed filtering device for pomegranate juice production, which relates to the field of juice production and comprises a support frame, and a filtering frame is mounted at the upper end of the support frame. Through the arrangement of the filter frame, the threaded rod, the filter screen, the movable groove, the adjusting frame and the adjusting rod, the filter screen installed in the filter frame and the adjusting frame in the device can be installed in an up-and-down attached mode, and meanwhile the adjusting rod installed in the device can adjust the front-back distance of the adjusting frame, so that the gap between the adjusting frame and the filter screen is changed; the pomegranate seed filtering and intercepting device can adapt to filtering and intercepting of pomegranate seeds of different sizes, through the arrangement of a filtering frame, a filtering net, an adjusting frame, an adjusting rod, a pushing plate, a pushing rod and a discharging opening, the pushing plate installed in the device can be pushed in the filtering frame through a sliding rail, and the filtered pomegranate seeds on the adjusting frame can be pushed; and the pomegranate seeds are pushed and taken out through the formed discharging opening.

The invention discloses a lipid-lowering and sugar-reducing soft capsule as well as a preparation method and application thereof, and belongs to the field of functional foods. The pomegranate seeds and the purple perilla seeds are uniformly mixed, compound co-extraction oil is obtained through supercritical extraction, and the soft capsules capable of efficiently reducing blood fat and blood sugar are further prepared. Experimental results show that the soft capsule provided by the invention can effectively stabilize the weight of a high-fat mouse, remarkably reduce the fasting blood-glucose, total cholesterol, triglyceride and low-density lipoprotein level of the high-fat mouse and increase the high-density lipoprotein level, and the effect of the soft capsule is superior to that of single pomegranate seed oil or purple perilla seed oil. The soft capsule provided by the invention is from a natural source, has the advantages of being green and safe, and lays a solid foundation for developing health-care foods which are beneficial to maintaining the health levels of blood sugar and blood fat and controlling in-vivo fat; meanwhile, a new raw material is provided for research on blood fat reducing and blood sugar reducing medicines. The method has prominent practical application value and wide application prospect.

1. Name of the design product: Pomegranate seed press. 2. Use of the design product: For pressing pomegranate seeds. 3. Design key points of the design product: Lies in the shape. 4. Picture or photograph that best shows the design key points: Front view.

The invention discloses pseudo-ginseng polysaccharide noodles and application thereof in maintaining blood sugar balance, and belongs to the technical field of food processing. The panax notoginseng polysaccharide noodles are prepared from the following raw materials in parts by weight: 20-30 parts of panax notoginseng polysaccharide, 5-15 parts of pomegranate seed extract, 20-30 parts of buckwheat flour, 20-30 parts of vital gluten, 15-25 parts of hawthorn fruit powder and 5-15 parts of corn stigma powder. Pseudo-ginseng polysaccharide is used as a main functional component, and pomegranate seed extract, buckwheat flour, vital gluten, hawthorn powder and corn stigma powder are used as auxiliary materials to prepare the noodles with the effect of maintaining blood sugar balance. The food is simple in preparation process, rich in nutrition, free of any additive, pure natural green food, moderate in hardness, high in rehydration rate, low in thread breaking rate and good in sensory quality.

The invention belongs to the field of daily chemicals, and particularly relates to a sour pomegranate seed extract and application thereof in whitening and skin care products. The preparation method of the sour pomegranate seed extract comprises the following steps: soaking sour pomegranate seeds in a lactic acid bacteria solution, and fermenting under a sealed condition; adding the fermented sour pomegranate seeds into liquid nitrogen for quick freezing, then performing freeze drying, and grinding into powder; the preparation method comprises the following steps: adding dried sour pomegranate seed powder into weakly alkaline water, treating with a colloid mill to obtain a suspension, performing ultrasonic-assisted extraction and ultrasonic treatment, adding a compound enzyme for enzymolysis, treating the solution after enzymolysis in an electric field, adsorbing with activated carbon, and filtering to obtain the sour pomegranate seed extract. The sour pomegranate seed extract disclosed by the invention has a relatively good whitening effect.

This invention relates to a peeling and seed-separating device suitable for wrinkled pomegranates. The device comprises a crushing pretreatment unit and a seed-collecting unit. A calyx collection channel is located at the lower left end of the device, corresponding to the crushing pretreatment unit, and a pomegranate seed collection port is located at the lower right end of the device, corresponding to the seed-collecting unit. A feed inlet is located on the left side of the device, corresponding to the crushing pretreatment unit. This invention features a scientifically designed and reasonable structure, stable operation, and strong interoperability between its various components, enabling continuous pomegranate seed extraction, saving time and improving work efficiency.

The present application relates to the biomedical field, and particularly relates to a kind of omnipotent stem cell culture medium containing maternal factors.The present application first uses maternal factors and pomegranate seed active peptide extract jointly to prepare omnipotent stem cell culture medium, the maternal factors in the culture medium are selected from TPRX1, TPRXL, miR-302 and IL1 alpha combination, verified analysis, the above-mentioned joint existence synergies, can effectively improve the expression of omnipotent stem cell in Oct3 / 4 gene and cell cluster number, further promote the induction capacity of somatic cell to omnipotent stem cell, so that the production of large quantities of omnipotent stem cell can be induced, meanwhile, the present application uses omnipotent stem cell culture medium as fibroblast proliferation-promoting culture medium, can effectively promote fibroblast proliferation, and is beneficial to the application in wound healing.

The application discloses a preparation method of high-purity sponge bone needles and application of the high-purity sponge bone needles in penetration promotion, and belongs to the technical field of sponge bone needles. The method comprises the following steps: cutting natural sponges, soaking the sponges in deionized water and performing ultrasonic oscillation, filtering, and cleaning to obtain pretreated sponges; subjecting the pretreated sponges to alkaline protease enzymolysis to obtain primary enzymolysis products; subjecting the primary enzymolysis products to ginger protease enzymolysis to obtain secondary enzymolysis products; and performing vacuum freeze-drying to obtain the high-purity sponge bone needles; the natural sponges are subjected to enzymolysis treatment by alkaline protease and ginger protease to obtain the high-purity sponge bone needles; and the sponge bone needles are used in surface grafting of wheat oligopeptides and loading of giant salamander skin collagen, pomegranate seed extract, Honeysuckle extract, Gotu Kola extract, early celery extract, iris extract, oyster shell extract and calcium chloride mixed treatment materials, so that the repair effect on skin inflammation acne is improved.

The grading screening equipment for pomegranate breeding comprises a screening box, two first screening plates are arranged in the screening box, the tops of the two first screening plates are connected with second screening plates in a sliding mode, a plurality of sliding grooves are formed in the two sides of the two first screening plates, and a plurality of limiting blocks are arranged on the two sides of the bottoms of the two second screening plates. The multiple limiting blocks are slidably connected into the multiple sliding grooves correspondingly, an adjusting assembly for adjusting the second screening plate is arranged on the second screening plate, a conveying assembly for conveying pomegranate seeds is arranged at the top in the screening box, and lifting assemblies for lifting the screening box are arranged on the two sides of the screening box. According to the seed screening device, through the adjusting assembly arranged on the second screening plate, the effect of adjusting according to seeds of different sizes is achieved, the accurate screening range can be set according to the seeds of different sizes, it is ensured that only the seeds meeting the standard can enter the next stage, and the overall quality of the seeds is improved.

The present invention relates to the field of separation control technology, and specifically to a control method and system for separating pomegranate extract and by-products. First, the present invention calculates the dissociation degree of pomegranate pulp and pomegranate peel through real-time image acquisition and a deep learning model, thereby monitoring the separation effect in real time and providing data support for subsequent control; secondly, the present invention uses the dissociation degree as a reward item for the PPO algorithm to dynamically control the working parameters of the ultrasonic generator and optimize the separation efficiency of the ultrasonic wave, thereby realizing effective control of the separation between the peel and the pulp; finally, the present invention proposes a Gaussian variable-speed equation for controlling the separation of by-products, and precisely controls the speed change of the centrifugal equipment according to the density difference between pomegranate seeds and pomegranate peel to ensure efficient separation of pomegranate seeds and peel at the optimal speed, thereby realizing precise control of by-product separation.

The utility model belongs to the technical field and provides pomegranate seed juicing equipment which comprises a box body, a containing cavity is formed in the box body, a hydraulic station is arranged in the containing cavity of the box body, a hinged door is hinged to one side of the containing cavity of the box body, and an arc-shaped plate is arranged on the upper surface of the box body. The fixing frame is connected with the upper surface of the box body, a hydraulic oil cylinder is arranged in the fixing frame, the hydraulic oil cylinder is connected with a hydraulic station through an oil pipe, and the telescopic end of the hydraulic oil cylinder is connected with an extrusion plate; the cylinder body is placed on the upper surface of the box body, the outer wall of the cylinder body is attached to the arc-shaped surface of the arc-shaped plate, and the cylinder body is communicated with a juice outlet pipe; the filtering barrel is placed in the barrel body and located under the extrusion plate, the diameter of the extrusion plate is smaller than the inner diameter of the filtering barrel, and the filtering barrel is detachably connected with the barrel body through a fastener. The design of the hydraulic oil cylinder and the squeezing plate is adopted, strong and stable squeezing force is provided through the hydraulic oil cylinder, and the juicing process of pomegranate seeds can be efficiently completed.

The invention relates to the technical field of health-care food, and particularly discloses a fermented beverage for relieving discomfort after drinking and a preparation method and application thereof.The fermented beverage comprises pomegranate seed extract and medicated leaven prepared through fermentation of composite yeast seeds containing aspergillus oryzae and saccharomyces cerevisiae, the pomegranate seed extract is pomegranate polyphenol extract, and in the pomegranate polyphenol extract, aspergillus oryzae and saccharomyces cerevisiae are added into the fermented beverage; the total polyphenol content is not lower than 40%, the resveratrol content is not lower than 1.5%, the fermented beverage further comprises malt, a malt extract, hovenia dulcis thunb, edible yeast, a radix puerariae extract and a radix puerariae flower extract, and the prepared fermented beverage is applied to food or health care products for accelerating ethanol metabolism in blood and relieving dizziness, nausea or weakness and discomfort after drinking. The product is stable in efficacy and suitable for preparing food or health care products with the hangover alleviating function.

The invention relates to the field of biomedicine, in particular to a totipotent stem cell culture solution containing maternal factors. The maternal factor and the pomegranate seed active peptide extract are jointly used for preparing the totipotent stem cell culture solution for the first time, the maternal factor in the culture solution is selected from a combination of TPRX1, TPRXL, miR-302 and IL1alpha, verification analysis shows that the combination has a synergistic effect, expression of an Oct3 / 4 gene and the cell colony number in the totipotent stem cell can be effectively improved, and the total cell colony number of the totipotent stem cell can be effectively increased. According to the present invention, with the application of the totipotent stem cell culture solution, the induction ability of the somatic cells to the totipotent stem cells can be further improved so as to induce the generation of the totipotent stem cells on a large scale, and the totipotent stem cell culture solution can be adopted as the fibroblast proliferation promoting culture solution so as to effectively promote the proliferation of the fibroblasts, such that the application in the wound healing aspect is easily achieved.