36 results about "Volatile drugs" patented technology

The invention relates to a coated medicine-carrying process for volatile medicament or oil form traditional Chinese medicine with mucosity such as borneol, which consists of dissolving the medicinal components and capsule material in organic solvent, stirring and charging into the aqueous phase of surface active agent, then performing cross-linking, aging, filtering and drying, thus obtaining coated medicine-carrying microcapsule or microsphere.

The disclosed drug detector based on animal olfaction comprises: a CCD camera, a brain stereotaxic instrument, an electrode, a pre-amplification and filter circuit, a multiarm maze, and computer control and analysis system. Wherein, according to animal brain olfaction cortex neuron electric action, letting animal produce specific memory to volatile drug; random putting drug in small rooms of the maze to give prize stimulation for specific brain area and reinforce the memory till animal action includes statistic meaning, collecting relative induced brain electric information to input computer for recognition and analysis and form training database.

The invention provides a volatile medicine with an eye health-care effect. The medicine is prepared from one or more of d-borneol essential oil, lavender essential oil, chamomile essential oil, calendula officinalis essential oil, rosemary essential oil, peppermint essential oil, grapefruit essential oil, benzoin essential oil, rose essential oil, geranium essential oil, jojoba oil, dalbergia odorifera essential oil, rose hip essential oil, frankincense essential oil, evening primrose essential oil, sandalwood essential oil, radix bupleuri essential oil, chrysanthemum essential oil, wolfberry essential oil, cassia seed essential oil, lemon essential oil, pomegranate seed essential oil, safflower essential oil and natural vitamin E. The volatile medicine is prepared from natural volatile medicinal materials, eyes are surrounded in the atmosphere formed after the medicinal materials are volatized, and the medicinal materials are slowly and mildly released. The volatile medicine can be applied to daily eye health care and is used together with an eye therapeutic apparatus.

The invention discloses a local high-pressure oxygen therapy apparatus which comprises a main air bag, an oxygen generating device, a massage device, a heating sheet and a treatment unit, wherein a cavity with an opening is arranged at one end of the main air bag, and a seal part is arranged in the opening; the oxygen generating device comprises an oxygen generator and a first pressure control mechanism, the oxygen generator is used for generating oxygen, and an oxygen outlet of the oxygen generator communicates with the inside of the main air bag through a first air inlet pipe and introduces oxygen into the main air bag; the first pressure control mechanism controls the air inflation quantity of the oxygen generator on the main air bag and keeps a gas pressure value in the main air bag within a range of 1-10KPa; the heating sheet is arranged in the main air bag and generates heat; and the treatment unit is detachably arranged in the position which is in the main air bag and corresponds to the heating sheet, and the treatment unit contains volatile drug ingredients under the heating effect.

The invention discloses a method for determining dimethyl sulfate in a drug through derivatization gas chromatography-mass spectrometry. The method comprises the following steps of adding a derivatization solution into a drug sample, deriving dimethyl sulfate into methyl iodide, and detecting the content of methyl iodide through gas chromatography-mass spectrometry to obtain the content of dimethyl sulfate, wherein the derivatization solution is a saturated sodium iodide aqueous solution added with a trace amount of sodium thiosulfate. By adopting the method, the content of the genotoxic impurity dimethyl sulfate in the medicine can be accurately determined, and the method has the advantages of being convenient to operate, being capable of reducing the interference of a non-volatile medicine matrix and the like.

The invention discloses a Chimonanthus nitense leaf drop pills for preventing common cold and preparation process, wherein the drop piils comprises (by weight ratio) 1,8cineole 1-10 parts and flavonoid glycoside 1-10 parts extracted from Chimonanthus intense leaves, water-based or oil-based base material 7-150 parts, excipient 0.01-10 parts.

The invention relates to an infectious disease prevention and control mask with a disinfection effect. The prevention and control mask comprises a plush protective mask which is integrally or locallyprovided with plush and can be used as a drug carrier without affecting breathing, and a medicament which can be attached to the surface of the plush, has adsorbability, can kill pathogenic bacteria and viruses, does not contain volatile drugs harmful to a human body, and does not have irritation and unpleasant odor. The prevention and control mask can play a better role in preventing inhaled tinydust, particularly inhaled and exhaled droplet pathogenic microorganisms, can kill the inhaled and exhaled droplet pathogenic microorganisms, and does not influence breathing smoothness after being worn. Besides, the mask can be worn for a long time, has the technical basis of repeated use, and is easy to treat after being discarded. The mask is more suitable for prevention and control of epidemic infectious diseases.

The invention discloses a traumatic rheumatism plaster which comprises an ointment and a medicinal plaster matrix. The ointment comprises traumatic rheumatism liquid extract which is prepared from flos carthami, radix saposhnikoviae, rhizoma zingiberis, unprocessed radix aconiti kusnezoffii, herba schizonepetae, unprocessed radix aconiti, radix angelicae, herba glechomae, rhizoma kaempferiae and unprocessed semen strychni. Volatile oil is extracted from medicine by adopting supercritical CO2 extraction technology in the preparation process, so that volatile oil extraction rate is increased, and damage to active ingredients is reduced; a volatile medicine inclusion compound is prepared by adopting inclusion technology, so that loss of volatile active ingredients in the process of preparing and storing a musk traumatic rheumatism plaster is reduced, and medicine efficacy is improved; a novel hydrophilic matrix is adopted, so that environment pollution caused by an organic solvent is avoided, allergic reaction which is prone to appearing in the process of medication is reduced, medication compliance of patients is improved, and the traumatic rheumatism plaster has remarkable treatment effect on rheumatism, swelling and joint pain.

The invention discloses a wearable portable atomization mask which comprises a mask body, a volatile medicine breathing channel is formed in the mask body, the volatile medicine breathing channel penetrates through the mask body, a liquid medicine injection storage tube is arranged on one side of the volatile medicine breathing channel, and a flexible solar cell panel is further arranged on the mask body; a control button is arranged at the bottom of the flexible solar cell panel, and a two-dimensional code used for recognizing medicine information is arranged on one side of the control button. When the mask is used, medicine injection, atomization and disinfection are integrated, the complexity of the device is reduced, and the operation is easy and convenient; accurate administration isperformed according to related data, so that the drug effect is improved; an atomization mode and a mask mode are adopted, and one mask has multiple functions; the periphery of the mask is attached toskin, a lacing structure of a traditional mask is omitted, and the requirements of special crowds are met; and the mask is simple and compact in structure, light and practical.

The invention relates to a plaster, in particular to a warm moxibustion plaster. The invention aims to solve the problem that all medicine molecules in an ointment layer are fully heated difficultly by an existing warm moxibustion plaster. Therefore, the warm moxibustion plaster comprises a base layer, a graphene electric heating ointment layer and a heat conduction insulating layer which are sequentially laminated from top to bottom; the graphene electric heating ointment layer comprises a graphene conductive network and volatile medicine particles attached to the graphene conductive network;the graphene conductive network is formed by paving a graphene conductive agent; the graphene conductive agent comprises a plurality of graphene sheets, and the graphene sheets can be attached to theoutsides of the volatile drug particles to attach the volatile drug particles to the graphene conductive network, namely, the medicine particles are dispersed throughout the whole graphene conductivenetwork; and when the conductive network forms infrared radiation, each volatile medicine particle attached on the conductive network can be rapidly and uniformly warmed to an appropriate temperature, and therefore, the treatment effect of the warm moxibustion plaster is greatly improved.

The present invention relates to a gas phase extraction and enrichment method for a liquid phase volatile material, and a system thereof. The system comprises a liquid-gas extraction unit and a gas phase compression enrichment unit, wherein the liquid-gas extraction unit adopts a specific gas as a working gas to extract a target volatile substance to a gas phase from the liquid phase so as to achieve liquid-gas phase transfer of the target volatile substance, and the gas phase compression enrichment unit adopts a special working liquid to absorb the working gas, such that a volume of the working gas containing the extracted target volatile substance is significantly reduced so as to achieve the gas phase compression enrichment of the target volatile substance. The method and the system in the present invention have good application prospects in volatile drug extraction, environment water body volatile pollutant enrichment and monitoring, and other fields.

There is provided a volatile medicine controlled release member capable of equalizing and controlling volatile release of medicine at a low concentration release speed, preventing unnecessary release by sufficiently dealing with a humidity change, and having a structure wherein a volatile volume is hardly affected even when a liquid volume of the medicine falls. The volatile medicine controlled release member is provided with a container with an interior filled with liquid medicine, a liquid absorber comprising a medium for sucking up the medicine, a space part for filling an interior with the medicine volatilized from the liquid absorber, and a humidity sensitive film with a permeation amount of the medicine changing in response to the humidity change. The medicine is sucked up and volatilized by the liquid absorber, and it is controllably released from the humidity sensitive film in response to the humidity change while it is retained at certain concentration in the space part formed by the liquid absorber and the humidity sensitive film.

The invention discloses a migraine treating instrument. The instrument comprises a head band and a fixing seat, the fixing seat clamps the two ends of the head band, a vibrator is embedded in the surface of one side of the fixing seat, the surface of one side of the vibrator mutually adheres to the inner wall of the head band, an application treatment box is bonded to the surface of the inner wallof the head band, seepage holes are formed in the surface of the application treatment box, absorbing cottons are bonded to the surface of the application treatment box, a feeding port is formed in the surface of the top of the application treatment box, and the surface of the head band is wrapped with a protecting rubber ring. By arranging the application treatment box, volatile medicines whichcan relieve migraine are conveniently added to the application treatment box through the feeding port formed in the surface of the top of the application treatment box, hot water or cold water can beadded, liquid seeps out to the absorbing cottons through the seepage holes formed in the surface of the application treatment box to perform application treatment on a patient, and therefore the painof the patient can be effectively relieved.

The invention relates to a preparation method of an emplastrum matrix capable of rapidly releasing volatile drugs, the emplastrum matrix is prepared by matching an SIS framework material with liquid paraffin, an antioxidant BHT and hydrogenated rosin glyceride, and the preparation method comprises the following steps: (1) synthesizing a linear SIS block copolymer; b, after the first block polymerization is completed, initiating a second block polymerization reaction; c, after the second block polymerization is completed, initiating a third block polymerization reaction; d, after the third block polymerization reaction is finished, 900-1100 ml of absolute methanol is added to terminate the reaction to obtain an SIS elastomer, the SIS elastomer is placed in a vacuum oven and dried at 48-52 DEG C for 10-14 h, and the dried SIS elastomer is obtained; and (2) preparing an emplastrum matrix. The preparation method disclosed by the invention is simple, can realize quick release of the medicine, has an accumulated release rate obviously higher than that of a process sample of an original prescription, not only reduces resource waste, but also provides a feasible method for improving the potential curative effect of a product, and has remarkable social and economic benefits.

The invention relates to animal pefloxacin mesylate pellets, and a preparation method thereof. The preparation method of the animal pefloxacin mesylate pellets comprises steps that: pefloxacin mesylate powder, a wall material which is a high-molecular material, and cyclohexane are placed in an organic solvent reaction vessel, and reflux is carried out for 1 to 2 hours under a temperature of 80 to85 DEG C; the temperature of the materials is reduced to 25 to 35 DEG C at a speed of 1 to 3 DEG C per 5 minutes, such that pefloxacin mesylate is coated with the wall, and pellets with sizes of 40 to 200 meshes are formed; the pellets are vacuum-dried, such that the animal pefloxacin mesylate pellets are obtained. According to the animal pefloxacin mesylate pellets provided by the invention, a high-molecular material or polymer is coated on the surface of the medicine, such that tiny sealed capsules are obtained, and the capsules serve as covers or protective films. Therefore, the bitter taste of the medicine can be covered; medicine stability can be improved; and volatilization of volatile medicines can be controlled. The animal pefloxacin mesylate pellets provided by the invention has advantages of convenient use, simple production technology, low cost, high medicine bioavailability, low irritation to intestines and stomach, and good medicine stability.

The invention relates to a method for preparing Chinese medicinal decoction capable of improving the availability of Chinese medicinal raw materials and preventing the loss of volatile components. The method comprises the steps of: adding Chinese medicinal materials into a sealed reaction kettle, heating, allowing volatile components to be condensed in the condenser tube of a condenser and flow back to the reaction kettle, rapidly cooling the reaction kettle, adding cosolvent, and subpackaging in sealed containers. The method can keep insoluble and volatile effective components in the decoction, so as to increase the concentration of effective components; and can maximally recover heat energy produced in decoction process, so as to reduce energy consumption. The obtained decoction has improved quality and therapeutic effect.

The invention discloses a light flash thermal desorption-delayed purging sample injection method for rapidly and simultaneously detecting volatile and non-volatile drug mixtures. A plurality of typesof drugs exist, and are large in difference of the structures and the molecular weights; and some drugs, which are not easy to volatilize, can reduce the sensitivity of a drug detection instrument utilizing thermal desorption sample injection, and meanwhile, influence the detection and identification efficiency of opium or new psychologically active drug mixtures. According to the method, the problem of rapid and simultaneous detection of the volatile-non-volatile drug mixture is solved; a halogen lamp is used for flash heating, so that the drug mixture is rapidly heated, the vapor pressure ofthe mixed sample is increased, the ionization efficiency at normal pressure is improved, and the signal intensity of the non-volatile sample in the mixture is improved by one order of magnitude or more; and by combining with a delayed purging device, the non-volatile and volatile substances volatilized during flash heating are purged into an ionization cavity at the same time, so that the loss ofsamples in the continuous purging and heating process is reduced, and the simultaneous detection of non-volatile and volatile drugs is realized.

The invention discloses a self-spill-proof extractor for volatile drugs, and belongs to the field of extractors. The self-spill-proof extractor for the volatile drugs is characterized in that through the arrangement of a bidirectional containing bag and a turning notch piece, when the drugs are extracted, a drug suction pipe is firstly inserted into an opening part of a container for containing the drugs, then inert gas is extruded into a container bottle, on one hand, the empty space in the container after the medicine is sucked can be effectively filled, then volatilization of the medicine is effectively restrained, on the other hand, the inert gas can effectively protect unstable volatile gas from being prone to oxidation reaction with air, when the medicine is sucked, the turning notch piece reversely deforms, the medicine enters the two-way containing bag, in addition, under the action of an outer isolation bag, the outside and the extraction opening in the container opening can be effectively isolated, and then medicine is effectively prevented from being volatilized to the outside during medicine extraction.

The invention relates to a high-activity slow-release pain-relieving patch and a preparation process thereof. The high-activity slow-release pain-relieving patch comprises a backing layer, a main body layer and an isolation layer which are sequentially stacked, wherein the main body layer comprises the following components: a matrix, active ingredients and an active ingredient slow-release inclusion material, wherein the matrix comprises 30-50wt% of a framework material and 12-28wt% of an auxiliary agent; the active ingredients comprise 6-12wt% of methyl salicylate, 5-8wt% of menthol and 1-4wt% of camphor; and the active ingredient slow-release inclusion material accounts for 6-18wt%. According to the high-activity slow-release pain-relieving patch, medicines with high activity and high volatility, namely methyl salicylate, menthol and camphor, are selected as the main body of the high-activity slow-release pain-relieving patch, and the active ingredients in the main body are included by adopting the slow-release inclusion material, so that the content of each active ingredient is kept to the maximum extent and is continuously and stably released, and the effectiveness of the medicines is ensured; and the matrix material with low sensitization and hydrophilicity is selected, and the preparation process adopts an innovative solvent-free production process technology, so that the transdermal patch is not easily allergic to a human body when being used for the human body, and the safety of the medicines is ensured.