933 results about "Microencapsulations" patented technology

The current invention, Supercritical Antisolvent Precipitation with Enhanced Mass Transfer (SAS-EM) provides a significantly improved method for the production of nano and micro-particles with a narrow size distribution. The processes of the invention utilize the properties of supercritical fluids and also the principles of virbrational atomization to provide an efficient technique for the effective nanonization or micronization of particles. Like the SAS technique, SAS-EM, also uses a supercritical fluid as the antisolvent, but in the present invention the dispersion jet is deflected by a vibrating surface that atomizes the jet into fine droplets. The vibrating surface also generates a vibrational flow field within the supercritical phase that enhances mass transfer through increased mixing. Sizes of the particles obtained by this technique are easily controlled by changing the vibration intensity of the deflecting surface, which in turn is controlled by adjusting the power input to the vibration source. A major advantage of the SAS-EM technique is that it can be successfully used to obtain nanoparticles of materials that usually yield fibers or large crystals in SAS method. Microencapsulation via coprecipitation of two or more materials can also be achieved using the SAS-EM technique.

The present invention provides methods for microencapsulation of active ingredients for topical application, whereby single-layer and multi-layer, preferably double-layer, microcapsules, are obtained. The microcapsules protect the active ingredients, maintain their original activity throught processing, formulation and storage, and enable controlled release of the active ingredient only upon application onto the skin.

Microencapsulated compositions containing haloacetanilide herbicides, i.e., acetochlor, are produced by microencapsulation process. The microencapsulated composition performs comparably to nonencapsulated compositions of the same herbicide applied at the same application rates.

A device and method for generating microcapsules employs an inertial-focusing channel for introducing particles dispersed in a prepolymer suspension fluid, a droplet-generating junction for introducing oil evenly onto the flow of particles to create separated droplets of prepolymer suspension fluid encapsulating respective particles in a streamline flow, and a polymerization section for exposing the droplets to UV light or heat to cause polymerization of a polymer coating on separate microcapsules each containing a respective particle. Preferred suspension fluids may be aqueous solution of poly(ethylene-glycol)-diacrylate (PEGDA), or poly(N-isopropyl-acryalmide) (PNIPAAM). The preferred device may employ a curved or linear inertial-focusing microchannel. Functional tags and/or handles may be added to the microcapsules allowing easy detection, measurement and handling of the microcapsules.

This invention describes a quick-dissolving thin film strips comprising bioactive components encapsulated within pH-sensitive polymeric microparticles. The microparticles are embedded within the thin film and provide protection to components encapsulated within. The invention further describes methods to incorporate bioactive components encapsulated within pH-sensitive polymeric microparticles into a quick-dissolving thin film strip while maintaining the bioactivity of the contained therapeutic agents during thin film formation and microencapsulation.

A composition comprising a core material, having a taste value and a polymeric coating. The polymeric coating substantially surrounds the core material and comprises a cationic polymer and optionally an anionic polymer. The polymeric coating has a uniform thickness ranging from 2 μm to 20 μm. The composition provides release of a portion of the core material which is taste masked over a time period ranging from 0.5 minute to 2 minutes in the oral cavity and provides a modified-release of the remaining core material in a gastrointestinal tract.

The invention provides microcapsule flame-retardant adsorption resin comprising a reservoir wall and a capsule core, wherein the capsule core comprises adsorption resin and flame retardant adsorbed in the adsorption resin. The invention further provides a preparation method of the microcapsule flame-retardant adsorption resin and a flame-retardant composite material. The higher strength adsorption resin with a three dimensional lattice structure is adopted as a support material; the flame retardant or a solution of the flame retardant is adsorbed into resin granules through hydrogen bonding or intermolecular force; and adsorbed flame retardant molecules, in particular to small flame retardant molecules, are very hard to separate out of the adsorption resin owing to the hydrogen bonding orthe intermolecular force, so as to effectively restrain the flame retardant from surface migration. Meanwhile, after microencapsulation of the adsorption resin with the flame retardant, the reservoirwall can further restrain the flame retardant molecules from separation and migration, so as to improve the migration resistance of the microcapsule flame-retardant adsorption resin.

The disclosure provides a polyurethane microcapsule consisting of a polymerization product of methylene diphenyl diisocyanate (MDI) prepolymer with a polyol, the polyurethane microcapsule comprising a liquid isocyanate compound encapsulated within the microcapsule. The disclosure also provides self-healing coating compositions comprising such polymeric microcapsules and methods of preventing or slowing corrosion using such coating compositions.

The invention discloses a core-shell synergistic flame retardant polyurethane microencapsulation expandable graphite and the application of the expandable graphite in rigid polyurethane foaming plastic. The core-shell synergistic flame retardant polyurethane microencapsulation expandable graphite comprises polyether and/ or polyester polyol, a foaming agent, a foam stabilizer, a catalyst, an organic phosphorus-based flame retardant, a halogen-free intumescent flame retardant, an organic modified nano inorganic filler, core-shell synergistic flame retardant polyurethane microencapsulation expandable graphite, polyisocyanate compound and isocyanate index, wherein the polyisocyanate compound has two or more isocyanate groups; the core-shell synergistic flame retardant polyurethane microencapsulation expandable graphite takes expandable graphite particles as a capsule core and takes cyclodextrin or polyurethane as a capsule shell, wherein the cyclodextrin or polyurethane is formed by crosslinking cyclodextrin/ modified resin and toluene diisocynate. The expandable graphite microcapsule can effectively improve the initial decomposition temperature, the heat stability and the flame retardant effect of a material and remarkably reduces the heat release rate and the total heat release quality during combustion.

The invention provides a lactobacillus helveticus microcapsule as well as the preparation and application thereof, pertaining to the embedding technology of lactobacillus helveticus and aiming at microencapsulating the lactobacillus helveticus so as to solve the problems of low embedding efficiency and embedding yield in single-layer or double-layer embedment. The technical proposal adopted by the invention is that isolated soy protein, microporous starch and sodium alginate are respectively taken as the first, the second and the third layers of wall materials for microencapsulation; the three-layer embedment is carried out to the lactobacillus helveticus for the first time, wherein, in the process of preparing bacterial suspension, an orthogonal optimization protective agent is adopted to improve the livability after freeze drying. The microcapsule of the invention has strong heat resistance and acid resistance, solves the inactivation problem caused by gastric acid, digestive enzyme and antibiotic, etc. to active bacillus, is capable of releasing when reaching large intestine, and balances intestinal flora. The reusability of fermented milk is good. The lactobacillus helveticus used by the invention enriches the variety of probiotic bacteria microcapsule and is a good dietary supplement.

The invention discloses a preparation method of a sustained-release water reducer microcapsules which belong to the technical field of building material additives. By miniemulsion inverse phase polymerization, common water reducer molecules undergo microencapsulation and the water reducer microcapsules which have a pH response function are synthesized. After polymerization is finished, the microcapsules are in an acidic condition. due to the existence of capsule shells, the water reducer molecules can stably stay in the microcapsules. After the microcapsules are mixed with cement, cement concrete is strongly alkaline and the microcapsules perform a response-stimulus behavior under a high pH condition. Large molecular chains of the capsule shells rapidly expand and extend so as to generatethe swelling phenomenon. The compact shell layer becomes loose, and the cladded water reducer molecules slowly release such that the concentration of the water reducer is always high in the cement concrete. Therefore, the fluidity etentivity with time of the water reducer can be raised, and the collapsed slump loss of cement concrete in practical engineering usage can be prevented.

An apparatus and method for encapsulating a liquid or suspension within a polymeric shell to form a microcapsule of a selected size ranging from approximately 0.1 μm to 1000 μm in diameter. The apparatus preferably has a laminar flow of air through a channel and ultrasonic atomizer with the head oriented at approximately ninety degrees from the laminar flow. Emulsions, liquids or thin films of core and shell materials are atomized and the formed microcapsules are exposed to ultraviolet light or additionally infrared light to cure the polymer shell and then are collected. A variety of capsule morphologies can be created by the choice of materials and process conditions to achieve desired controlled or programmed release kinetics. Surface functionalization of the outer shell of the microcapsules capsules can also be achieved to facilitate targeted delivery.

This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide, a sugar and a salting-out salt.

Compositions and methods for producing encapsulated cells having an average diameter of less than about 200 μm are provided. Methods for using the disclosed encapsulated cells are also provided

An encapsulated material containing an oxidation-sensitive core is covered by at least a dried phospholipid layer, and contains at least one phytosterol in the core, the phospholipid layer or in a further layer or layers. By using microencapsulation, oxidatively unstable materials may be provided with a synthetic protective barrier and rendered less susceptible to oxidative degradation.

The present invention relates to an enzyme electrode useful for estimation of cholesterol in aqueous medium, said electrode comprising: i. an electrically conductive base plate, ii. a film of sol gel derived material deposited thereon, said sol gel derived material of step b) being microencapsulated cholesterol oxidase with an electron mediator. The present invention also relates to a process for the preparation of an enzyme electrode by coating an immobilized cholesterol oxidase (ChOx) and mediator on a silicate sol gel by microencapsulation.

A suspension of microcapsules in an organic liquid, the microcapsules containing an aqueous phase, is produced by interfacial polymerization in the presence of a proton transfer catalyst of a water-in-oil emulsion in which the aqueous phase contains a urea/formaldehyde or melamine/formaldehyde prepolymer.

The invention provides a method for generating a homogeneous aqueous mist solution containing a solvent such as water and a biocide agent such as chlorine dioxide, which would otherwise be unstable. The unstable biocide agent or chlorine dioxide is quickly dissolved or mixed with a mist of solvent causing the biocide agent to co-exist or co-mist therewith. The mist microencapsulates the biocide gas so that it does not decompose in the fumigation volume or space. The resulting homogenous mist solution provides a mist for delivering the biocide agent in a chemically stable form. Methods for mixing the separately generated mist and biocide gas include combining the mists in a Y-tube and then mixing the combination in a baffled mixing chamber, combining the mists in an area above their points of generation and then further mixing, and providing a series of mist generation units connected by a conduit for a carrier medium to pass to and connect the units and cause the mists to combine. Alternatively, the biocide may be released from a controlled source to dissolve in a generated solvent mist. Such controlled release of biocide includes providing a source of slow diffusion of chlorine dioxide gas to dissolve in water mist by convection and mixing, providing a continuous flow of chlorine dioxide solution via a coil reservoir for controlled contact with the mist, providing chlorine dioxide gas released from a solid-state mixture.

The invention provides a graphene-based heat conduction silica gel phase change composite material comprising silicon substrate and heat conduction phase change material dispersed in the silicon substrate. The heat conduction phase change material comprises heat conductive filler and microencapsulation phase change material, and the heat conductive filler is selected from one or more of graphene, alumina powder, aluminium nitride powder and carbon nanotube. The composite material adds the heat conductive filler into silica gel, and can form a complete heat conduction access in the silica gel, so that the thermal conductivity of the composite material is improved. Moreover, the microencapsulation phase change material is added into the silica gel, the latent heat of the composite silica gel material is improved, and a part of heat can be stored as heat conduction. Meanwhile, the heat conduction is effective as the synergism of heat conduction silica gel and phase change material.

The invention relates to an instant powdery grease treating starch sodium octenylsuccinate as a wall material. The instant powdery grease comprises 30-70% by mass of the wall material, 5-60% by mass of grease, 5-60% by mass of an auxiliary wall material, 0.5-3% by mass of an emulsifier, 0.1-2% by mass of an antioxidant and 0.1-0.5% by mass of a cosolvent. The invention also relates to a preparation method of the powdery grease. The preparation method is characterized in that a microencapsulation technology is adopted to embed fat-soluble grease in order to prepare a microcapsule, the wall material used for embedding is starch sodium octenylsuccinate, the addition of the emulsifier and the addition of the auxiliary wall material improve the emulsification shear speed, improve the homogenization pressure and increase the homogenization frequency, grease is embedded in the wall material and undergoes spray drying, and the addition of the cosolvent forms the instant powdery grease. The preparation method has the advantages of simplicity and low cost, and the prepared powdery grease has the advantages of good water solubility, fast dissolving, high oil carrying amount, and good fluidity and can be applied to the food field, the daily-use chemical engineering field, the medicine field and the like.