353 results about "P phosphate" patented technology

The invention relates to a betaine phosphate-containing feed additive for improving net energy level and a preparation method and application thereof, and belongs to the technical field of feed additives, the preparation method comprises the following steps: preparing composite betaine phosphate, preparing composite zinc methionine, and mixing; the preparation of the composite betaine phosphate comprises the following steps: preparing a betaine phosphate crude product, preparing a composite silicon dioxide carrier, and crystallizing; the preparation of the compound zinc methionine comprises the following steps: preparing an activated silicon dioxide carrier, adsorbing starch and adsorbing the zinc methionine; in the step of mixing, the compound betaine phosphate and the compound zinc methionine are mixed and then stirred at room temperature, and the betaine phosphate-containing feed additive capable of improving the net energy level is obtained. The feed additive prepared by the invention has a strong effect of improving the net energy level of broiler chickens, is not easy to have the problems of bonding and clustering, and is good in storage resistance.

The application specifically discloses a phosphate-based positive electrode material and a preparation method and application thereof. The phosphate-based positive electrode material comprises base particles and a carbon coating layer coated on the surface of the base particles; the chemical formula of the base particles is Li x M y PO4, 0.96≤x≤1.08, 0.96≤y≤1, M comprises at least one of Fe and Mn; wherein, the M site is doped with a first metal element, the first metal element comprises at least one of Ti, V, Cr, Co, Ni, Nb, Mo and W; and / or, the Li site is doped with a second metal element, the second metal element comprises at least one of Mg and Zr; the carbon coating layer comprises a carbon material, and the degree of disorder I D / I G of the carbon material is ≤1.2. The application has the advantages of improving the electrochemical performance of the phosphate-based positive electrode material and reducing the ion elution rate thereof.

Disclosed is a phosphate e precursor, which has a chemical formula of LixMy(PO4)(x+y) / 2Az·wH2O, where M is a transition metal element selected from one or more of Fe, Ti, V, Cr, Ni, Co, Mn, Al, Nb, Y, Zr, Sb, Mo, Sn, and Ce, A is one or more of F, OH, CO32−, C2O42−, and O2−; and 0.5≥x<1.2, 0.5<y≥1, 0≥z≥1, and 0.1≥w<8. The phosphate precursor has good uniformity, contains crystal water, and exhibits excellent structural stability, and can be used to prepare olivine-type phosphate cathode material through sintering at a low temperature of 260° C.-600° C.; and the phosphate precursor is blended with a carbon source and is subjected to heat treatment to obtain carbon-contained cathode material, which has good electrochemical properties.

According to the cell fixing liquid, phenol oxidase is used for catalyzing phenol to be oxidized into a quinone structure, the quinone structure reacts with protein amido to form light covalent immobilization, cell immobilization is achieved, a stable hydration environment and membrane protection are provided through the ionic liquid solvent choline dihydrogen phosphate, a phosphate-free buffer system is provided, and cell immobilization is achieved. Therefore, a novel cell fixing liquid is obtained, the cell structure integrity required by cell imaging analysis is effectively reserved, meanwhile, cell staining fluorescence signal interference is avoided, and therefore the accuracy of cell counting and cell imaging analysis is ensured.

A negative electrode material for secondary battery use includes silicon-containing particles and coating layers covering at least part of the surfaces of the silicon-containing particles. The silicon-containing particles each include an ion conductive phase and silicon phases dispersed in the ion conductive phase. The coating layers contain at least one phosphate compound selected from the group consisting of a phosphate compound, a polyphosphate compound, and a metaphosphate compound, each of which contains an anion represented by general formula (1):In general formula (1), A represents an organic group or an oxygen atom.

Provided is an optical filter, including an absorbing glass substrate composed of phosphate-based glass or fluorophosphate-based glass; a bonding layer with a single layer structure; and a resin layer, wherein the resin layer is provided on the absorbing glass substrate through the bonding layer, wherein the bonding layer includes a Si atom and one or more selected from a Ti atom, a Zr atom, and an Al atom; or an optical filter, including an absorbing glass substrate composed of phosphate-based glass or fluorophosphate-based glass; and a resin layer, wherein the resin layer includes a Si atom and one or more selected from a Ti atom, a Zr atom, and an Al atom, and is provided on the absorbing glass substrate.

A sodium iron phosphate pyrophosphate positive-electrode material and a preparation method thereof, a battery, and an energy storage device are provided. A molar ratio A of sodium element to iron element in the sodium iron phosphate pyrophosphate positive-electrode material of embodiments of the disclosure satisfies 1.36≤A≤1.45.

A positive electrode material and a preparation method therefor, a positive electrode, and a battery are provided. The positive electrode material includes an iron-based phosphate material. The iron-based phosphate material includes a first active material and a second active material. A chemical formula of the first active material is Na4Fe3(PO4)2P2O7. A chemical formula of the second active material is Na2FeP2O7. A mass fraction of the first active material in the iron-based phosphate material is a1. A mass fraction of the second active material in the iron-based phosphate material is a2. a1 and a2 satisfy: 0<a2 / a1≤0.2.

The present compositions and methods relate to thermostabilization of phytase with phosphate and increasing the recovery of phytase during the production of heat-treated food or animal feed pellets that contain phytase.

An active material of the positive electrode comprises secondary particles (2). Each of the secondary particles (2) comprises primary particles (1). Each of the primary particles (1) comprises an olivine-type phosphate compound. A portion of the surface of the secondary particle (2) has a depression (3). At the depression (3), the surface of the secondary particle (2) is concave. A cross-section of the secondary particle (2) satisfies the relationship "0.41 ≤ Sa / Ca ≤ 0.95". "Sa" represents the area of ​​the cross-section of the secondary particle (2). "Ca" represents the area of ​​the smallest circumcircle of the cross-section of the secondary particle (2).

The invention relates to a method for detecting genotoxic impurities of rupatadine fumarate, which is characterized in that a phosphate buffer solution is matched with acetonitrile, a high performance liquid chromatography method is adopted, a chromatographic column is a silica gel bonded octadecylsilane column, a gradient program is adopted for elution, and the content of the rupatadine fumarate genotoxic impurities in the rupatadine fumarate genotoxic impurities in the rupatadine fumarate genotoxic impurities is detected. Effective separation between rupatadine fumarate and genotoxic impurities and between genotoxic impurities can be achieved, accurate quantitative analysis can be achieved, and the quality of drugs can be effectively controlled.

The invention belongs to the technical field of battery materials, and particularly relates to a method for determining iron phosphide in a phosphate positive electrode material, the positive electrode material and application. Comprising the following steps: preparing standard solutions of a series of phosphate positive electrode materials with different iron phosphide contents; respectively collecting and purifying magnetic substances in the standard solutions, and adding a quimocilidone reagent to determine the corresponding quinoline phosphomolybdate precipitate; drawing a standard curve according to the mass of the iron phosphide and the mass of the quinoline phosphomolybdate precipitate in the standard solutions with different iron phosphide contents; preparing a to-be-detected solution, collecting and purifying magnetic substances in the to-be-detected solution, adding a quinmolybdenum citronone reagent to determine the mass of the quinoline phosphomolybdate precipitate, and calculating the content of iron phosphide in the to-be-detected phosphate positive electrode material. By means of the method, the content of trace iron phosphide in the phosphate positive electrode material can be efficiently, accurately and quantitatively analyzed, the content of iron phosphide in the phosphate positive electrode material can be quantitatively regulated and reduced, and the electrochemical performance of the phosphate positive electrode material is improved.

The present application provides a detection method and quality control method for related substances in dextromethorphan oral solution, which comprises the following steps: dissolving dextromethorphan oral solution in a solvent to obtain a test solution; and performing high performance liquid chromatography detection on the test solution; the mobile phase used in the high performance liquid chromatography detection comprises mobile phase A and mobile phase B, the mobile phase A comprises a phosphate solution, the mobile phase B comprises acetonitrile, and the concentration of the phosphate solution is 0.1 mM-10 mM. The detection method has good linear relationship between dextromethorphan and related substances, good accuracy and sensitivity, strong specificity, high stability, good separation degree and good reproducibility, and is suitable for wide application.

The invention relates to a pyridoxal phosphate (PLP) synthesis method based on cascade biological catalysis and capable of realizing ATP autonomous regeneration. The method comprises the following steps: constructing engineering bacteria for co-expressing pyridoxal phosphate kinase (PdxK) and polyphosphate kinase (PPK) to prepare a whole-cell catalyst or a crude enzyme solution; under the condition that ATP does not need to be exogenously added, pyridoxal, ADP and polyphosphate serve as substrates, cascade reaction is carried out under the action of a catalyst, ATP is regenerated in situ, and PLP synthesis is driven. A wild enzyme system is adopted, and the yield of PLP exceeds 95% within 4 hours of reaction; after PdxK mutation optimization, the reaction time is shortened to about 2 hours, and conversion can be completed. According to the invention, a polyphosphate-driven ATP regeneration system is coupled with PLP biosynthesis, so that the cofactor cost is remarkably reduced, a feasible technical path is provided for industrial biological manufacturing of PLP, and the application of polyphosphate in cyclic regeneration of cofactors is expanded.

The invention discloses a stage targeting scallop adductor non-phosphorus water-retaining agent containing antifreeze glycopeptide and application, and relates to the technical field of food additives. The antifreeze glycopeptide-containing stage targeting scallop adductor phosphorus-free water-retaining agent consists of an agent A and an agent B, and does not contain phosphate additives, the agent A is permeable anti-freezing liquid and is prepared from the following components in percentage by mass: 5.0 percent to 9.0 percent of trehalose, 3.0 percent to 5.0 percent of sorbitol, 0.8 percent to 1.5 percent of sodium citrate, 0.4 percent to 1.0 percent of compound amino acid, 0.01 percent to 0.1 percent of high-activity anti-freezing glycopeptide, 0.01 percent to 0.05 percent of vitamin C, 0.01 percent to 0.05 percent of rosemary extract and the balance of water. According to the antifreeze glycopeptide-containing phase-targeting scallop adductor non-phosphorus water-retaining agent and the application thereof, ice crystal damage and protein denaturation are inhibited from the source, and cell-level protection of scallop adductors is realized. Through detection, the unfreezing loss rate of the treated scallop adductor is as low as about 2.12%, the cooking loss rate is as low as about 10.63%, and the water retention capacity is close to that of a commercially available phosphate water retention agent and is remarkably superior to that of an existing non-phosphorus water retention agent.

The invention provides a kit for quantitatively detecting VEGF (Vascular Endothelial Growth Factor) by using a chemiluminescence method as well as a preparation method and a detection method of the kit. The kit comprises a VEGF reagent 1 which is a diluent 1; the VEGF reagent 2 comprises a peroxidase-labeled VEGF antibody and a diluent 2; the VEGF coated plate comprises a VEGF coated antibody, a diluent 1, a diluent 3, a diluent 4 and a chemiluminescent plate; the diluent 1 is a phosphate buffer solution; the diluent 2 is a Tris buffer solution containing fetal calf serum and an HRP enzyme stabilizer; the diluent 3 is a carbonate buffer solution; and the diluent 4 is a phosphate buffer solution containing sodium caseinate and a light-emitting plate stabilizer. According to the detection kit, the double antibody sandwich method immunoassay principle is combined with enzyme labeling and catalytic chemiluminescence immunoassay, the content of the VEGF is quantitatively determined, the detection kit can be prepared with low cost, accurate determination of the VEGF can be achieved, and the detection kit has high sensitivity and good stability.

The present invention relates to a use of an enzyme belonging to the aldolase group and comprising a polypeptide having at least 30% identity with an amino acid sequence selected from SEQ ID NO: 1 to SEQ ID NO: 4, for stereoselectively preparing D-tagatose-1,6-bisphosphate (TBP) or D-tagatose-1-phosphate. The present invention also relates to a method for preparing D-tagatose-1,6-bisphosphate (TBP) or D-tagatose-1-phosphate, comprising a step of reacting, in a suitable reaction medium, dihydroxyacetone phosphate (DHAP) or at least an isomer thereof or analog thereof, and optionally D-glyceraldehyde, with an enzyme belonging to the aldolase group, said enzyme comprising a polypeptide having at least 30% identity with an amino acid sequence selected from SEQ ID NO: 1 to SEQ ID NO: 4. Finally, the present invention relates to a process for preparing D-tagatose.

The invention relates to a method capable of monitoring physiological phosphate, in particular to a colorimetric sensor array based on MIL-101 (Fe) and a preparation method and application of the colorimetric sensor array. Nitro and amino are attached to MIL-101 (Fe), and a sensor array is constructed based on the three kinds of Fe-MOFs. Sensing image information of phosphate before and after a reaction in a colorimetric sensor array is obtained, RGB difference values of all colorimetric points before and after the reaction are obtained to obtain an LDA image, the lowest detection limit can be as low as 0.1 mu M. The array not only has good discrimination capability on ten phosphate compounds such as ATP, ADP, AMP, adnosine, Pi, PPi, UTP, GTP, ITP and CTP, but also has good detection effect on phosphate compounds such as phosphate compounds. And under the condition that interferents (ions, amino acids and the like) are contained, accurate identification can be realized. The colorimetric sensor array can also distinguish different PPs in fetal calf serum. The metal-organic framework sensor array has a good prospect as a novel college sensing platform of phosphate and other disease-related biomolecules.

The application provides a glucose detection test strip and a preparation method and application thereof. The preparation method of the glucose detection test strip comprises the following steps: taking copper sulfate pentahydrate, a phosphate buffer solution, glucose oxidase and horseradish peroxidase, mixing uniformly to obtain an enzyme-containing mixed solution; immersing a test strip in the enzyme-containing mixed solution, and obtaining an organic-inorganic hybrid nanoflower loaded test strip after reaction; immersing the organic-inorganic hybrid nanoflower loaded test strip in a mixed solution containing a chromogenic agent, a gel, bovine serum albumin and polyethylene glycol to obtain a glucose detection test strip. The preparation method of the glucose detection test strip has higher sensitivity and shorter response time.

The invention belongs to the technical field of medical polymer materials, and particularly relates to a preparation method of a surgical anti-adhesion hydrogel material. The material is prepared from 2, 3-diformylbenzoic acid modified gelatin, 3, 4-dihydroxyphenylethylamine, sodium hyaluronate, sodium tripolyphosphate, hydrogen peroxide, ascorbic acid and a phosphate buffer solution. Modified gelatin powder is obtained through a grafting reaction of 2, 3-diformylbenzoic acid and gelatin, then the modified gelatin powder, 3, 4-dihydroxyphenylethylamine and an auxiliary agent are prepared into a main gel solution, hydrogen peroxide and ascorbic acid are added before use, and the main gel solution is quickly crosslinked into gel under the body temperature condition. The obtained hydrogel can be stably combined with the tissue surface, the degradation process is matched with tissue repair, and the hydrogel has a free radical scavenging effect. Animal experiments show that the material can effectively reduce abnormal adhesion between postoperative tissues and has a good clinical application prospect.

The application discloses a self-curing material capable of enhancing the holding force of an oral implant, and a preparation method and application thereof. The self-curing material comprises the following components: a solid phase component and a liquid phase component; the solid phase component is composed of a mixture of a phosphate and a phosphosilicate bioactive glass; and the liquid phase component contains chitosan and phytic acid. The application further provides the self-curing material and application thereof as a biological medical material for oral use. The self-curing material can enhance the holding force of the oral implant, promote the formation of hydroxyapatite, a main component of bone tissue, and thus is favorable to the formation of new bone and further enhances the bone combination capacity of the implant.

The invention relates to a preparation method and application of a tooth antibacterial and mineralized dual-function anti-caries material. The anti-caries material provided by the invention comprises two components, namely a mineralizing solution I and a mineralizing solution II. The mineralization liquid I contains polyelectrolyte and soluble salt of antibacterial metal cations; and the mineralization liquid II contains phosphate and fluoride. The pH values of the two mineralizing solutions are both 9.5 + / -0.5. During use, the surface of a demineralized tooth is firstly cleaned, the mineralizing liquid I and the mineralizing liquid II are sequentially coated, flushing is performed after each action for 15 minutes, 1-3 cycles are performed every day, and continuous treatment is performed for 7-14 days. Through polyelectrolyte template guiding and antibacterial metal ion doping, a biomimetic mineralization layer with an antibacterial function is formed on the surface of the demineralized tooth, and the dual functions of antibacterial and remineralization are achieved. The material can significantly recover the mechanical properties of teeth, the elastic modulus and hardness recovery rates respectively reach 68.6% and 62.5%, the dental caries score is reduced by 70% or more, and the dental caries prevention material has an excellent dental caries prevention effect and a clinical application prospect.

One embodiment of the present specification provides a method for preparing a low-crystallinity calcium phosphate-based antibacterial bone graft material, comprising the steps of: (a) adding a calcium precursor and a phosphate precursor at one time to synthesize calcium phosphate; (b) putting the calcium phosphate into an antibacterial substance precursor solution to react; (c) a step of freeze-drying the product of step (b); (d) a step of mixing the product of step (c) with a shape control agent and performing press molding to prepare a molded body; and (e) a step in which the shape control agent of the molded body is removed in a solvent having a temperature equal to or higher than the boiling point and then dried.

The invention relates to the technical field of preparation of organic silicon functional materials, and particularly discloses an integrated preparation method of bis-[gamma-(triethoxy silicon) propyl] tetrasulfide-chloromethyl phenethyl triethoxy silane mixed silane, which comprises the following steps: by taking a chloropropyl triethoxy silane-chloromethyl phenethyl triethoxy silane mixture as a raw material, carrying out one-step reaction on the raw material to obtain bis-[gamma-(triethoxy silicon) propyl] tetrasulfide-chloromethyl phenethyl triethoxy silane mixed silane, and carrying out one-step reaction on the bis-[gamma-(triethoxy silicon) propyl] tetrasulfide-chloromethyl phenethyl triethoxy silane mixed silane; in the whole process, a reaction system and process parameters are reserved and designed around the function of chloromethyl phenethyl triethoxy silane, and the overall production efficiency is improved by shortening the time consumption of a sodium sulfide synthesis procedure; the target mixed silane is prepared through four core processes of sodium sulfide synthesis, sodium polysulfide in-situ preparation, selective vulcanization in a phosphate buffer system and product homogenization in sequence. According to the invention, a one-step integrated preparation method is innovatively adopted to replace a traditional compounding process, the total impurity content of the product is less than 0.6%, the equipment investment cost is reduced, and the overall production efficiency is improved.

The invention relates to a preparation method of stepped cross-linked myofibril-pectin core-shell hydrogel microspheres, which comprises the following steps: preparing a myofibril protein dispersion liquid and a pectin solution by using a phosphate buffer solution containing NaCl as a solvent; preparing an anthocyanin stock solution by taking a phosphate buffer solution as a solvent; mixing the three components under an ice bath condition, and then reacting at 2-5 DEG C for 1-3 hours; 2) dropwise adding the reaction solution obtained in the step 2) into a continuously stirred CaCl cross-linking solution at 2-5 DEG C, standing and curing after dropwise adding, and washing with distilled water to obtain single-layer hydrogel microspheres with uniform particle size and smooth surface; and naturally draining the surface moisture of the single-layer hydrogel microspheres, soaking the single-layer hydrogel microspheres in a freshly prepared 1-4% pectin solution for 20-40 seconds, then taking out the single-layer hydrogel microspheres, transferring the single-layer hydrogel microspheres into another CaCl crosslinking solution, and continuing crosslinking for 10-20 minutes to form a compact shell structure. And after the reaction is completed, washing with distilled water. The core-shell hydrogel microspheres can be used for detecting volatile ammonia, monitoring and indicating pork freshness and the like.

The invention belongs to the technical field of resveratrol synthesis, and particularly relates to a preparation method of resveratrol and application of resveratrol in meat preservation. The method comprises the following steps: taking 3, 5-dimethoxybenzoic acid as a raw material, and carrying out acylation reaction to obtain 3, 5-dimethoxybenzoyl chloride. Then reacting with p-acetoxystyrene to generate 3, 3 '-dihydroxy-3, 3'-dihydroxy-3 The preparation method comprises the following steps: taking 1, 5-dimethoxy-4 '-acetoxystilbene as a raw material, hydrolyzing and demethylating to obtain resveratrol, and preparing resveratrol lipid nanoparticle suspension by taking resveratrol, a ZIF-8 / chitosan compound, compound lipid, cholesterol, epsilon-polylysine, ascorbyl palmitate and phosphate buffer saline as raw materials. High load and controlled release of resveratrol are achieved, and the problems that resveratrol is poor in water solubility and prone to oxidation are solved.

A bone substitute composition includes a bone substitute matrix and a conditioning solution. The bone substitute matrix includes 85% to 98% by weight of alkaline calcium phosphate powder, 1% to 10% by weight of a polymer, and 1% to 5% by weight of a crosslinker. The conditioning solution includes 90% to 97% by weight of water, 1% to 5% by weight of a phosphate, and 1% to 5% by weight of a water-soluble acidic compound.

This application belongs to the field of battery materials technology, and particularly relates to a phosphate-based cathode material and its preparation method, as well as a cathode sheet and a secondary battery. The phosphate-based cathode material includes a phosphate-based active material core and a shell layer covering the outer surface of the core. The shell layer includes a modified Al2O3 inner layer and a conductive polymer outer layer sequentially covering the outer surface of the core. The modified Al2O3 inner layer includes an Al2O3 substrate and F and Ta elements chemically bonded to the substrate. The conductive polymer outer layer includes a polyaniline-lithium phytate composite material. In the phosphate-based cathode material, the double-shell coating structure effectively inhibits the dissolution of metal ions such as manganese, improves interfacial stability, thereby significantly reducing interfacial side reactions, simultaneously enhancing electronic and ionic conductivity, improving rate performance, and greatly increasing cycle life.

This document describes poultry diets containing phytase polypeptides or fragments thereof, in which the diet contains no or practically no inorganic phosphate.

The present application relates to a kind of metal phosphate oligomer surface-coated layered structure positive electrode material and its preparation method and application.The metal phosphate oligomer surface-coated layered structure positive electrode material includes: inside is layered structure positive electrode material, surface is metal phosphate oligomer;The structure general formula of the layered structure positive electrode material is LiXO2, wherein X is selected from at least one of Co, Mn and Ni;The metal phosphate oligomer contains metal ion and phosphate anion, structure general formula is M x (PO4) y ;Wherein M is at least one of Li, Ti, Sn, Mn, Zr and Al, preferably Li and Zr, more preferably Li: Zr=1: (0.25~3).