396 results about "Spheroid" patented technology

The invention relates to a method for producing UV polarizers, according to which spheroid particles situated near the surface of the glass are incorporated into the support material (primarily standard float glass) in a novel arrangement. According to the method for producing UV polarizers, after the introduction of metal ions (e.g., silver ions) into the glass surface, a large size distribution of particles is achieved by multiple alternation of a heat treatment for separating out spherical metal particles, followed by the renewed introduction of metal ions and a subsequent heat treatment. A deformation of the glass produces spheroid particles of various sizes and different semi-axis relationships. The particles are characterized by their large size distribution and are deformed differently in relation to their spheroid shape. In this way UV polarizers are produced which have a wide absorption range since the absorption bands having different maximum positions overlap.

The present inventors identified aggregation of embryonic stem cells and embryoid bodies (EBs) as the cause of the difficulty in generating large numbers of the embryonic stem cells (ES) cell-derived tissues. To counter this, the invention provides a novel bioprocess where aggregation of spheroid forming cells, such as embryonic stem cells and spheroids, such as EBs is controlled, such as by encapsulation of within a matrix. As a result, EBs can be generated with high efficiency and cultured in high cell density, well-mixed systems. Well-mixed conditions facilitate measurement and control of the bulk media conditions and allow for the use of scalable bioreactor systems for clinical production of tissue. Therefore, the invention enables generation of ES cell-derived tissue on a clinical scale. The invention is also applicable to any spheroid-forming cells and other types of pluripotent cells.

The invention herein of a spherical connector and supporting rod assembly is mainly designed as a structure of a multi-angular spheroid with multiple tangent planes of six cubical quadrilaterals and twelve beveled hexagons, and with mounting holes disposed respectively at the centers of the quadrilateral and the beveled hexagonal tangent planes to make each spherical connector having eighteen mounting holes with included angles pointing at different directions so as to increase the application of a single spherical connector and to make all the spherical connectors have the identical structure for exchangeable connection to not only fully comply with the needs of specific application, but also to be able to make various applications by using the supporting rods pointing at different mounting angles to directly fulfill the specific need of the assembly.

The invention discloses a method for solving rigidity of a plate spring by using an automatic dynamic analysis of mechanical system (ADAMS). The method comprises the following steps of: step one, determining basic dimension parameters of the plate spring according to a design paper of the plate spring; step two, establishing a three-dimensional model by employing CATIA software to perform reasonable segmentation, and selecting necessary coordinate points; step three, establishing a Point hard-point, a Box block and a Beam beam in an ADAMS/View, putting forward an equivalent middle surface method in attribute setting of the Beam beam, and establishing contact force Contact; and step four, setting a simulation analysis environment of a stress-deformation curve of the plate spring, and employing a method for loading loads through contact of a flat plate and a spheroid to obtain a simulation curve. The method solves the problems in establishing a plate spring flexible body model through the ADAMS software, and the problems in performing simulation setting on the stress-deformation curve of the plate spring flexible body model, and has important meanings for improving the modeling, analyzing and solving accuracies and the calculation speed of mechanical simulation software.

A novel method, using a thermoreversible MC/PBS/Collagen hydrogel coated on the TCPS dish, for harvesting a living cell sheet or spheroid with ECM. In one application, the obtained living cell sheet/spheroid is administered to a joint adapted for implantation and for cartilage regeneration. In another application, the living cell sheet/spheroid is administered, preferably via percutaneous injection, to an infarcted cardiac tissue as a novel therapy for treating myocardial infarction.

The invention discloses a model box applied to a large stereoscopic synthesis simulation test bench in geotechnical engineering, wherein four sides of the model box are spliced by a plurality of horizontal loading plates; the top of the model box is formed by splicing a plurality of vertical loading plates; each horizontal loading plate is connected with a horizontal loading actuator through a spheroid joint; each horizontal loading actuator is fixedly connected with a reaction wall through connection bolts; each vertical loading plate is connected with a vertical loading actuator through a spheroid joint; each vertical loading actuator is fixedly connected with a reaction beam; sealing joint strips are embedded between the side surfaces of the adjacent horizontal loading plates. The model box disclosed by the invention can be applied to a simulation test of soil engineering with different functions, such as underground space and excavation simulation tests, foundation and slope engineering simulation tests under the condition of rain and underground water level variation, dynamic response tests of pile foundations and soil around the pile foundations, segment simulation tests, and structure part performance tests; simultaneously, due to the adoption of the model box, the true three-dimensional loading of a large-sized physical model is realized.

Provided are a method capable of evaluating adherent cells under an environment similar to an in vivo environment by a culture method similar to a two-dimensional culture, and applications thereof. An adherent cell culture method uses, as a culture chamber (10), a chamber in which two or more culture spaces each having an equivalent diameter (D) that is 1 to 5 times the diameter of a desired spheroid and each having a height (H) that is 0.3 to 5 times the equivalent diameter are arranged and a surface of each of the culture spaces has a water contact angle of 45 degrees or less. Spheroids of adherent cells are cultured in the respective culture spaces (11) arranged in the culture chamber (10).

The invention relates to a microfluidic device for culturing spheroids of human or animal body cells. The device can generate ample numbers (e.g., 5000) of uniform-sized spheroids, and the spheroids can be harvested for conventional biochemistry analysis (e.g. flow cytometry). In addition, the device can be used for observing the cultured samples using selective plane illumination microscopy (SPIM). In at least one embodiment, the microfluidic device incorporates a main body; a fluid channel extending inside the main body and having two inlets and an outlet open to the outside; and a plurality of chambers for culturing cell spheroids which are formed at the underneath of the fluid channel.

The invention belongs to the technical field of preparation of nano materials, and in particular relates to a super hydrophobic self-cleaning coating and a preparation method thereof. The method comprises the following steps of: dispersing hydrophobic silicon resin and hydrophilic nano SiO2 particles into an organic solvent to obtain dispersion; and spraying the dispersion on a clean and dry glass sheet substrate, drying, and thus obtaining the super hydrophobic self-cleaning coating. The coating has a hierarchical structure compounded by using organic and inorganic components, namely the hydrophobic silicon resin and the hydrophilic nano SiO2 particles, and the structure has compound micro-nano surface topography; and the compound micro-nano hierarchical structure is constructed by spheroid-like protrusions with the diameters of 1 to 10 microns and agglomerate spheres with the diameters of 20 to 100 nanometers on the surface of the coating, wherein the spheroid-like protrusions are constructed by agglomerate spheres with the diameters of 20 to 100 nanometers. The contact angle between the coating and water is 140 to 155 degrees, and the rolling angles of water drops on the surface of the coating are less than 2 degrees.

The present invention concerns methods for the ex vivo formation of mammalian bone and subsequent uses of the bone. A critical and distinguishing feature of the present invention are defined tissue culture conditions and factors resulting in the formation of bone cell spheroids. The invention also provides for methods of implanting into subjects the ex vivo formed bone. Also described are methods for genetically altering the bone cell spheroids to affect bone formation, identification of candidate modulators of bone formation, and identification of genes involved in bone formation.

The invention discloses high specific surface area silver powder improving conductivity of a solar battery electrode and a preparation method. The silver powder has an average particle size of 0.6-0.75 micrometers, an apparent density of 2.5-5.0g/mL, a tap density of 4.15-6.95g/mL and specific surface area of 0.45-0.75m<2>/g. The method comprises the steps of preparing a silver nitrate solution and a reducer solution, adding a dispersing agent, performing parallel flow addition of various reaction system solutions into a reaction vessel by twice in a twice addition manner, uniformly mixing the reaction system solutions for the first time, keeping a PH value and temperature of reaction liquid as 2-5 and 25-60 DEG C, continuing stirring for 10-30min after feeding, and adding a mixed reaction solution in a parallel flow addition manner with the addition volume of 0.25-0.75 time of the total addition volume of the first time. The silver powder is a spheroid covered with bulges on the surface, is uniform in particle size and has a good crystal surface and high dispersity; the photoelectric conversion efficiency can be improved when the silver powder is used as front silver electrode slurry of crystalline silicon solar battery; the silver powder particularly has excellent characteristics in aspects of short-circuit current, contact resistance, fill factor and the like.

The microporous ceramic ball for comprehensive control of plant growth belongs to the field of microporous ceramic. It is irregular spheroid comprising core of complex structure and tightly connected sintered shell, the core is one complex microporous structure of randomly combined compact structure and loose structure, and the sintered shell is microporous structure with fertilizer particle adsorbed inside the pores. The present invention also discloses the composition and preparation process. The present invention has antibiotic function of killing various kinds of bacteria, function of regulating soil humidity of soil, and function of releasing infrared ray and releasing plant nourishing matters and trace elements to promote plant growth, and may be used in the plantation of high grade flower and other plant.

Parenchymal cells are cultivated on cultivated endothelial cells or cultivated fibroblasts which have been separated by a surface of a specific hydrophilic polymer, and which have been patterned. A culture which contains thus formed patterned spheroids of cultivated parenchymal cells is thereby provided by this invention. This culture maintains a function which is specific to the parenchymal cells over a long period of time.

An assembly of two elements including a first element that has a cavity with an external opening connected to a first region defined by a sidewall that is a spherical segment and the diameter of the external opening is smaller than the diameter of the sidewall in the first region. Adjacent to the first region is a second region also defined by a second spheroid segment that is separated from the first region by an annular ring extending from the sidewalls towards a central axis of the cavity. The annular ring forms a passage having a diameter approximately the same as the external opening. An extension member on the second element is inserted into the cavity which has a first rod section terminating in a second spherically-shaped section. The spherically shaped section has a diameter larger slightly larger than the external opening on the first element and accordingly, the spherical section may be snap-fitted through the external opening to a first position in a first region, and be retainer there and, it may be further snap-fitted through the passage to the second region and be retained there. Also disclosed is flange structure that engages an annular seat when the spherically shaped member is in the second position.

The invention discloses an energy collecting system comprising a substrate; a photosensitive layer selectively disposed on the substrate; and at least one convex lens disposed on the photosensitive layer. The shape of the convex lens is a semi-spheroid, thinner semi-spheroid, semi-columned, or thinner semi-columned shape. The convex lenses are arranged in an array order and are coated with an anti-reflection layer.

Provided is a full-automatic multifunctional solar life-raft which can not be overturned when being unfolded, and comprises a survival capsule, an automatic extension arm, a divided storage chamber and counterweight. The survival capsule is composed of pluralities of annular air sacs, arc air sacs and double-layered outer covers. The roof of the survival capsule is provided with a solar cell panel cover, the bottom of the survival capsule is provided with a power bay and the divided storage chamber, the middle of the survival capsule is provided with the automatic extension arm for supporting. A dismountable counterweight chamber is arranged under the storage chamber, sail lift-off balloons which can be folded for storage are installed in the solar cell panel cover, cabin doors and sail balloon bags are in interval arrangement by pluralities of double-layered outer covers, folded sail balloons are arranged inside the sail balloon bags, and an engine, an electric air pump, a sea water purifier, a divided storage box and pluralities of lifesaving articles are arranged inside the sail balloon bags. The life-raft is a multifunctional lifesaving appliance which can automatically advance, travel by wind force and even lift off, being powered by solar energy, the sea water purifier and the pluralities of lifesaving articles can prolong the survival time of casualties as long as possible, and the life-raft which is just a spheroid after being deflated and recovered is easy to be placed on boats.

An autonomous stratospheric unmanned airship with an operating altitude from 5-22 km and with a mutli-month operational cycle. Spheroid rigid geodesic frame of constant volume formed by a multitude of struts, with an outer envelope enclosing the frame defining the eigenfrequency spectrum of the airship above 20 Hz, with vibrational amplitudes between 0.1 and 1 cm. Independently controllable electrical propulsion units, attached to the frame in the horizontal plane passing through the center of mass, can change the direction and value of the thrust vector. Buoyancy is controlled with a system integrated inside the geodesic frame including buoyant fluid pressurized tanks, valves for the release of the buoyant fluid through the buoyant fluid conduit into the buoyant gas cell which fills the geodesic frame. Valves at the subsystem support platform enable ambient atmosphere to fill the internal volume of the frame not occupied by the buoyant gas cell.

The invention relates to a heat treatment method of a bearing. The heat treatment method comprises the following six steps of: heating, insulating, quenching, cleaning, cold treatment and tempering. The heat treatment method is characterized in that before the heating step, a fining treatment step of carbide is arranged; the fining treatment step comprises two steps of forging and spheroids annealing; the temperature of initial forging in the forging steps is 1050-1150 DEG C; the insulating time is 70-90 minutes; the temperature of the final forging and forming is 800-900 DEG C; then the stirring and cooling are carried out in boiling water till the temperature is 300-600 DEG C; the bearing is taken out of water and air-cooled till room temperature; and the spheroids annealing step comprises specific steps of: heating to 790-810 DEG C, insulating for 150-210 minutes under the temperature, air cooling to 680-710 DEG C, insulating for 4-6 hours, cooling till 650 DEG C along with a furnace, taking out of the furnace and carrying out air cooling. The cold-treatment step is carried out in 2 hours after the cleaning steps is finished after quenching, liquid nitrogen is adopted as cooling medium, cooling is carried out till the temperature is minus 70-minus 80 DEG C, insulation is carried out for 1.5-2 hours under the temperature, and returning the temperature naturally till the room temperature. The heat treatment method has the advantage that the service life of the bearing is prolonged by fining carbide particles, improving the hardness and controlling the content of the retained austenite in the metallographic structure.

The invention provides a trivector hydrophone based on a piezoelectric velocity sensor, which comprises a spheroid, and hanging elements, a velocity sensor and a multi-core output tape cable all arranged in the spheroid, wherein the velocity sensor comprises three piezoelectric velocity sensors which are connected in sequence through connecting rods; one end of the four hanging elements is fixed on the middle piezoelectric velocity sensor, while the other end extends out of the spheroid; and the spheroid is a solid sphere. The average density of the vector hydrophone approximates to the water medium density; the channel sensitivity is high in a working frequency band below 2,000 hz and is irrelevant to the frequency; the vector hydrophone has good cosine directivity; and the vector hydrophone is not limited by an obliquity during working. The vector hydrophone can be widely used in various fields of hydroacoustics, such as sonobuoys, low noise motion target measurement, target orientation and the like.

The present invention belongs to technology field of manufacturing metal powder, which specifically relates to a method and a device of manufacturing spheroid metal and alloy granular by making use of uniform liquid drop spray application techniques. Inert gas used by the present invention is bled into a crucible and a vacuum tight chamber that can obtain steady differential pressure by means of pressure control system, which makes mental fusant ejected in the form of laminar jet from a micro-nozzle positioned on a bottom of the crucible. Vibration disturbance mental shooting flow produced by a piezoelectric oscillator turns metal shooting flow into uniform droplets. And real-time size parameters of the droplets mentioned-above can be obtained by camera system and computer analysis software. Subject to the optimum parameters, frequency of control oscillator is fed back, thereby reducing size error of the metal droplets and predetermined droplets. The present invention is able to directly manufacture granular that is homogenized in size, shape and thermodynamic condition. The present invention has short technological process and products have good quality, which greatly reduces equipment investments.

A rotating wall vessel is used as a culture vessel and bioreactor for the cultivation of hepatocytes in the form of spheroids to generate a culture with many properties of the intact liver. These properties include enzyme activity comparable to fresh cells and long-term maintenance of viability and cellular function for periods on the order of months. The cultures may be used to produce hepatocyte products, evaluate metabolism of an agent, propagate Hepatitis C virus and test agents as inhibitors of this virus. Thus, the culture system disclosed herein makes long term functional cultivation of human hepatocytes feasible.

An inflatable device serving in one or more roles as furniture and/or equipment for exercise, recreation, and/or therapeutic equipment, or in some combination of these functions is disclosed. The device consists of an inflatable base (2) with one or more cavities or holes, with rounded inflatable spheroid(s) (1) in said cavities or holes. The device may optionally include a system of straps (3 and 4) or a form-fitting covering around the base, which may serve to correct an asymmetry in said base. The device may include a weighted base (11). The device may also include means for generating lights, sound, and/or video (6, 7, 8, 9, 10, 12, and/or 13) responsive to the actions of users on or around the device.

The invention provides a copper-graphene composite and a preparation method thereof. The preparation method at least comprises the following steps: (1) mixing graphene and a proper amount of copper to prepare a spheroid of which the diameter is 0.5-1 cm; (2) putting a copper material into a vacuum device, preheating the vacuum device, and vacuumizing to reach 10<-4> to 10<-3> Pa, wherein the mass of graphene accounts for 0.1-5% of the total mass of graphene, copper and the cooper material; and (3) injecting protective gas to reach 500 to 1000 Pa, heating the vacuum device till the copper material is molten, putting the spheroid into a copper solution in the molten state, stirring, pouring the copper solution together with the molten spheroid into a mold immediately after the spheroid is molten, and cooling to the room temperature in the atmosphere of the protective gas, so as to obtain a copper-graphene composite ingot. The copper-graphene composite prepared by adopting the preparation method provided by the invention is high in electrical conductivity, and the graphene distribution is uniform.