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1001 results about "Animal body" patented technology

Aerial vehicles with proximity sensors for safety

ActiveUS12227318B1CapacitanceProximity sensor
An aerial vehicle or another system having moving components may be configured with a capacitive sensing system for detecting body parts of humans or other animals within proximity. The capacitive sensing system includes conductive components provided in association with surfaces of housings within which motors rotate propellers or other objects. The capacitors are coupled to circuits including transistors, resistors, capacitors or other features that are configured to determine levels of capacitance on the conductive components during operations of the aerial vehicle or other system. When a body part approaches a conductive component, and disrupts a level of capacitance on a capacitor coupled to the conductive component, a change in the level of capacitance on the capacitor is detected. Where the change exceeds a predetermined threshold, predetermined actions such as stopping or otherwise altering operations of the motors may be performed.
Owner:AMAZON TECH INC

Livestock breeding state monitoring method and system

The invention provides a livestock breeding state monitoring method and system, and relates to the technical field of data processing, and the method comprises the steps: setting an RFID chip and a health monitoring sensor on each animal body; acquiring a multi-modal sensor data sequence of the animal in the time window; preprocessing the sensor data sequence; respectively extracting hidden states of various sensor data sequences through a long-short term memory neural network; based on a self-attention mechanism, adding a self-attention weight to the hidden state at each moment; obtaining intermediate monitoring results corresponding to the various sensor data sequences according to the hidden states and the self-attention weights of the various sensor data sequences; an independent channel is configured for each intermediate monitoring result in the full-connection network; based on a channel attention mechanism, adding a channel attention weight for each channel; and based on the weight of each channel, summarizing various intermediate monitoring results, and determining a comprehensive monitoring result.
Owner:TUOKESUN FENGCHENG STATE OWNED ANIMAL HUSBANDRY CO LTD

Adjuvant and application thereof in vaccine preparation

The invention discloses an adjuvant and application thereof in vaccine preparation. The amino acid sequence of the adjuvant is shown as SEQ ID NO: 5, 7, 9, 11, 13, 15, 17, 19, 23, 27, 31, 35 or 39. The immune protection effect of the nanoparticle vaccine can be improved by activating TLR2, and good vaccine adjuvant activity is shown in a common immunogen SD or new coronavirus RBD immunogen model. Furthermore, an assembly construction method of the self-adjuvant-nanoparticle vaccine is optimized, and the prepared self-adjuvant-nanoparticle vaccine has a remarkable effect of inducing the generation of an antibody in an animal body. The novel adjuvant provided by the invention can be widely applied to vaccine research and development, and meanwhile, the assembled nanoparticle self-adjuvant vaccine can also become a novel vaccine.
Owner:SUN YAT SEN UNIV

Bio-Recharge System to Normalize Body Functions

PendingUS20250332434A1Light therapyDiseaseWhole body
The current invention provides a biocompatible energy recharge system to normalize body functions for a mammal. Both stationary and circulatory scalar wave energy was produced and utilized to enable the entire body of a mammal to increase the energy potential of any cell in the body, to promote cell growth, to facilitate cell repair, and to reduce cell destruction, hence the cells, organs, systems and the entire body of a mammal become healthy, and to treat a disease or disorder. The invention is a combination of the generators of the three-dimensional bio-waves in the stationary and in the circulationary formats for empowering the cells in all parts of a mammal, and a method of using the 3D bio-waves uniformly to empower each organ of a mammal to restore and maintain the normal body health and function.
Owner:TESLA BIOHEALING INC

Communication and powering systems and methods between implantable and wearable devices

A system includes a wearable device and an implantable device. The wearable device includes one or more signal transmitters and is configured to be positioned adjacent to or in contact with a human or animal body. The implantable device includes a signal receiver and is configured to be implanted onto or within the human or animal body. The one or more signal transmitters of the wearable device are configured to transmit the signals through the human or animal body to the signal receiver of the implanted device via a galvanic coupling operable using electro-quasistatic signal transmission. The system also includes a capacitive element positioned on an electrical current flow path of the galvanic coupling between at least one of the one or more signal transmitters and the signal receiver.
Owner:PURDUE RES FOUND

A system for determining posture of moving objects by means of a radar and a method therefor

The present disclosure relates to a method for determining a posture representation of a human or an animal body moving in an environment, the method comprising: obtaining, by means of an ISAR radar system, ISAR images comprising range and cross-range information characterizing the body appearance in the environment over time; extracting, from the plurality of ISAR images and by means of an image-to-image translation deep neural network, iTDNN, spatiotemporal information for respective moveable skeleton joints of the body; and combining the extracted spatiotemporal information for the respective moveable skeleton joints, thereby obtaining a posture representation of the body.
Owner:INTERUNIVERSITAIR MICRO ELECTRONICS CENT (IMEC VZW)

Detection and localization of disease utilizing fluorescence spectra of exogenous fluorophores

The present discloses systems and methods for tissue analysis, biopsy, and treatment utilizing at least exogenous fluorophores and near infrared light. A method is disclosed for optically determining the presence of abnormal cells, such as cancer, in tissue. The method includes applying one or more exogenous fluorophores into tissue in an animal body, wherein the exogenous fluorophores include a targeting moiety formulated to bond with a selected site on abnormal cells. The method includes illuminating the one or more exogenous fluorophores in the tissue with near infrared light from an elongated optical probe to generate fluorescent light from exogenous fluorophores present in the tissue. The method includes receiving fluorescent light generated from the one or more exogenous fluorophores in the tissue. The method includes determining if abnormal cells are present in the tissue based on the fluorescent light generated from the one or more exogenous fluorophores in the tissue.
Owner:PREVIEW MEDICAL INC +1

Method for predicting body mass of herd animal, computer-readable storage media, system for predicting body mass of herd

A method for predicting body mass of herd animal that comprises the steps of: collecting data from the livestock environment; detect and select the animal; determining geometric characteristics of each RGB-D depth image; and obtaining the prediction of herd animal body mass. Furthermore, the present invention relates to a system for predicting body mass of herd, comprising: at least one RGB-D capture set including at least one RGB-D imaging sensor; at least one storage module; and at least one remote monitoring module; wherein the storage module stores a set of instructions that, when executed by a processor, carries out the method for predicting body mass of herd animal.
Owner:L THIELO DE LA VEGA LTDA +1

Implantable animal data detector and detection method thereof

According to the implantable animal data detector and the detection method thereof provided by the invention, the main body and the sealing cover which are in threaded connection are adopted to seal an internal component of the shell and are implanted into an animal body, so that the internal component of the shell is effectively isolated from an external organism, and the safety of the animal body is ensured while the internal component is ensured to stably run for a long time; by integrating a temperature sensor, an acceleration sensor and a gyroscope sensor, the body temperature, activity data, lying posture and other data of the implanted animal can be rapidly and accurately collected in the animal body, the behavior and physiological state of the animal can be rapidly obtained through an external receiving device, and therefore early warning of animal diseases is achieved; early intervention treatment is realized, the normal production cycle of animals is prevented from being influenced by diseases, and the production benefit is improved; in addition, a strong magnet is arranged in the shell, so that the detector can be conveniently and safely taken out from the animal body through an external magnet when needed, and the injury to the animal and the operation risk are reduced.
Owner:HANGZHOU QIANPAN TECHNOLOGY CO LTD

A system and method for translating animal data into a language understandable by ai models to communicate with and about the animal body

PCT designated stage expiredWO2024259122A2Medical data miningTherapiesSyntaxAnimal body
An animal data language system includes an animal language computing system configured to execute one or more animal data language models to infer discriminative information describing input animal data requiring analysis, the one or more animal data language models applying a biodata language derived from animal data, the biodata language including patterns of data that operate as one or more words, characters, symbols, signs, phrases, and / or units of digital information, the biodata language including a lexicon and syntax rules for the lexicon, wherein the animal language computing system is trained to receive the input animal data and to output the discriminative information in the biodata language.
Owner:SPORTS DATA LABS INC

Application of RuO2 nano-enzyme in preparation of medicine for treating osteoarthritis

The invention relates to the field of osteoarthritis drug treatment, in particular to application of RuO2 nano-enzyme in preparation of a drug for treating osteoarthritis, and particularly relates to knee osteoarthritis. The RuO2 nano-enzyme disclosed by the invention is prepared according to the following method: carrying out incubation deposition on Cu2O sphere nano-particles and RuCl3 to obtain Cu2O and RuO2, and etching Cu2O and RuO2 spheres to obtain the RuO2 nano-enzyme. The RuO2 nano-enzyme provided by the invention is a hollow RuO2 nano-enzyme sphere, and after the RuO2 nano-enzyme is horizontally used in an animal body for intervention, the hollow RuO2 nano-enzyme sphere can be used as a hollow RuO2 nano-enzyme sphere; the RuO2 nano-enzyme can effectively delay the development of knee osteoarthritis of a mouse knee osteoarthritis model caused by medial meniscus instability (DMM), improve the pain condition and movement function of a DMM modeling mouse, reduce the gonarthromeningitis degree and relieve knee joint cartilage degeneration and injury, and the effectiveness of the RuO2 nano-enzyme in delaying the knee osteoarthritis disease is further proved. The invention provides a novel method for treating knee osteoarthritis, and has strong practicability and application prospect.
Owner:NANJING DRUM TOWER HOSPITAL

Double-recognition fluorescent molecular probe, preparation method thereof and application of double-recognition fluorescent molecular probe in detection of lead ions and / or glyphosate

The invention discloses a double-recognition fluorescent molecular probe, a preparation method thereof and application of the double-recognition fluorescent molecular probe in detection of lead ions and / or glyphosate, and relates to the technical field of detection of lead ions and pesticide glyphosate. The double-recognition fluorescent molecular probe disclosed by the invention is a Schiff base type probe which takes dicyanoisophorone and benzoyl hydrazine as fluorophores. The invention also relates to application of the double-recognition fluorescent molecular probe in lead ion sensing detection. The complex of the double-recognition fluorescent molecular probe and lead ions can be used for sensing detection of glyphosate. The double-recognition fluorescent molecular probe provided by the invention has the advantages of easily available raw materials and simple operation. According to the present invention, the quantitative detection of the lead ions / or the glyphosate by the probe through the different functions displayed by the ultraviolet and fluorescence spectra is achieved, the reversibility is strong, the multi-time cyclic utilization can be achieved, the selectivity is good, the influence by other metal ions is not easily generated, the detection limit is low, and the excellent application imaging is provided in animal bodies such as cells, zebra fish and the like.
Owner:HARBIN SHENGTAI BIOLOGICAL PHARM CO LTD

Device for constructing intervertebral disc degeneration model by using mouse simulation

The invention provides a device for constructing an intervertebral disc degeneration model by using mouse simulation, and belongs to the technical field of medical research. Comprising a mounting base plate, a supporting rod is connected to the middle of the top of the mounting base plate, a top seat is fixedly connected to the top of the supporting rod, and a ring seat is fixedly connected to the inner side of the top seat. The body clamping mechanism can accurately clamp an animal body, is matched with an electric push rod to realize bending or unfolding of the body, and is matched with the limb positioning mechanism to improve the experiment suitability and assist in simulating the pathological process of human intervertebral disc degeneration, the limb positioning mechanism fixes the limbs of the animal through antiskid plates, and the device can adapt to animals with different sizes and is high in practicability. The rotating shaft design avoids animal limb fracture, the angle adjusting assembly and the arc-shaped displacement assembly enable the animal limbs to flexibly swing and move up and down, the convenience and the adjusting adaptation performance of the device are improved, and more accurate data and reliable experiment conditions are provided for lumbar vertebra pathological research on the whole.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Method for shearing tissue

A method is described for shearing a tissue wall between a first cavity and an adjacent second cavity in a human or animal body. The tissue wall has a periphery forming an edge of an opening between the first cavity and the second cavity. A first member is placed into the first cavity, such that the first member is adjacent the wall. A second member is placed in the second cavity, proximate the first member. The first and second members have materials which magnetically attract one another. The first member and the second member are placed such that there is magnetic attraction between the first member and the second member through the wall and thereby compress an overlapping portion of the wall to create pressure necrosis. The first member and the second member are connected by a thread, wherein the thread extends over the edge of the opening.
Owner:UNIV LIBRE DE BRUXELLES

Implantable gamma-aminobutyric acid detection system and dynamic real-time calibration method

The invention relates to an implantable gamma-aminobutyric acid detection system, which belongs to the technical field of neurochemical detection and comprises an implantable microelectrode array device, a signal detection circuit module, a first wireless data transceiving module, a second wireless data transceiving module and a detection terminal. The invention also provides a dynamic real-time calibration method. The method comprises the following steps: implanting the implanted microelectrode array device into an animal body; measuring two paths of electrochemical impedance data between the working electrode and the reference electrode and between the calibration electrode and the reference electrode by using a signal detection circuit module; calculating an estimated value of the concentration of gamma-aminobutyric acid by adopting an improved Randles circuit model; estimating the measurement error of the gamma-aminobutyric acid concentration by using an artificial neural network; and calibrating the measurement error to obtain a gamma-aminobutyric acid concentration detection value.
Owner:CHONGQING UNIV OF POSTS & TELECOMM

Autonomous livestock monitoring

The present invention provides a method and a system for monitoring the mobility levels of individual farm animals and accordingly determining their corresponding mobility score. The mobility score may be indicative of the health and / or welfare status of the animals. The present invention processes a 2D video recording obtained from an imaging device to detect the movement of individual animals through a space. The video recording is segmented over a set of individual frames and in each frame the individual instances of the animal appearing in the vide frame are detected. The detected instances of each animal over a number of frames are grouped together. From each detected instance of an individual animal a set of reference points are extracted. The reference points are associated with location on the animal body. The present invention determines the mobility score of each animal by monitoring the relative position between reference points in each frame and the relative position of each reference point across the set of individual frames associated with an animal.
Owner:CATTLE EYE LTD

Classical swine fever virus subunit vaccine and preparation method thereof

The invention provides a classical swine fever virus subunit vaccine and a preparation method thereof, the classical swine fever virus subunit vaccine is based on an E2 protein gene and a GP67 signal peptide gene of a CSFV 1.1 strain, a recombinant expression vector is constructed through gene cloning, a classical swine fever virus E2 recombinant protein is obtained through expression of an insect baculovirus system, and the classical swine fever virus subunit vaccine is obtained. And the recombinant protein is combined with a colloidal manganese adjuvant to prepare the swine fever virus subunit vaccine. The hog cholera virus E2 recombinant protein is close to natural E2 protein in structural function, high in reduction degree, high in expression quantity and suitable for vaccine production and application; the vaccine can generate specific humoral immunity and relatively strong cellular immunity, and is beneficial to removal of CSFV in an animal body; meanwhile, the vaccine can be distinguished from attenuated vaccine strain immunization or wild strain infection at the nucleic acid level, can be used for preventing and purifying classical swine fever in an intensive pig farm, and has a considerable application prospect.
Owner:GIANTSTAR FARMING & ANIMAL HUSBANDRY CORP LTD

Smeglutide long-acting sustained-release microsphere and preparation method thereof

The invention provides a semeglutide long-acting sustained release microsphere and a preparation method of the semeglutide long-acting sustained release microsphere. According to the method, the semeglutide long-acting sustained-release microspheres are prepared based on a water-in-oil-in-oil (W / O / O) phase separation method. According to the method, the problems of low drug loading capacity and high burst release of a water-in-oil-in-water (W1 / O / W2 type) multiple emulsion method are solved; meanwhile, the particle size of the long-acting and sustained-release microspheres of the semeglutide is between 10 microns and 300 microns, the particle size distribution Span value is between 0.5 and 1.5, and compared with a control drug, the long-acting and sustained-release microspheres of the semeglutide have no burst release effect and no drug release lagging stage after being administrated, have the same onset time as the control drug in an animal body, can be slowly released for one month and have a remarkable blood glucose reducing effect.
Owner:ZHEJIANG POLY PHARMA

Assembly comprising a medical device adapted to be implanted and packaging for said device

The invention relates to an assembly formed by a medical device (1) adapted to be implanted in a human or animal body and by packaging, wherein: —the medical device comprises a housing (11) that encloses a fluid reservoir (13) and a fluid outlet (12) forming a fluid connection between the reservoir and a volume outside the housing; —the packaging includes a tank (2) comprising a bottom (20), a side wall (21), an upper face opposite the bottom in a vertical direction, and an opening configured to fill the tank with a biocompatible fluid, the bottom (20) of the tank extending in a horizontal plane perpendicularly to the vertical direction; —at least one of the bottom, the side wall and the top face comprises a first holding element (201) adapted to hold the housing in the tank, the housing (11) being held in the tank (2) by said first holding element (201) such that the reservoir is located between the bottom of the tank and the fluid outlet, said fluid outlet being arranged below the opening such that the fluid outlet is immersed in the fluid when the tank is filled with the biocompatible fluid.
Owner:UROMEMS

Implantable occlusion system

An occlusion system implantable in a human or animal body, including a fluidic circuit which includes an inflatable occlusive sleeve, a reservoir with variable volume filled with a fluid. The reservoir includes a fixed portion and a movable portion, an actuator mechanically coupled with the movable portion of the reservoir to linearly displace the movable portion relative to the fixed portion for adjusting the volume of the reservoir. The actuator and the reservoir are laid out in a sealed casing containing a gas. A sensor mechanically bound to the actuator and / or to the movable portion, measures a traction and / or compressive force of the movable portion of the reservoir. Also included is a device for measuring the fluid pressure in the fluidic circuit.
Owner:UROMEMS

Weissella confusa DY12 with probiotic activity and its application

ActiveCN119955687BBacteriaAnimal feeding stuffBiotechnologyWeissella confusa
The present invention relates to the technical field of the development and utilization of probiotics, specifically to a Weissella confusa DY12 with probiotic activity and its application. The Weissella confusa DY12 was isolated from sheep feces. The present invention identified the probiotic effect of Weissella confusa DY12 through animal experiments. The results showed that Weissella confusa DY12 could tolerate acid and bile salts and resist the gastrointestinal internal environment; its hydrophobicity was 39.47% and its auto-aggregation was 48.12%, demonstrating that the Weissella confusa DY12 of the present invention has good intestinal adhesion ability and has the potential of probiotics. The present invention verified that Weissella confusa DY12 can effectively regulate the immune function of the animal body, improve the antioxidant capacity of the body, as well as the content of lysozyme and the activity of alkaline phosphatase, and increase the daily weight gain, ultimately improving the growth performance of animals.
Owner:SOUTHWEST UNIVERSITY FOR NATIONALITIES

Drug-guided anti-inflammatory enhanced mesenchymal stem cell preparation and application of drug-guided anti-inflammatory enhanced mesenchymal stem cell preparation in improvement of osteoarthritis

The invention discloses a drug-guided anti-inflammatory enhanced mesenchymal stem cell preparation as well as a preparation method and application thereof. By constructing the medicine-loaded mesenchymal stem cell preparation, the immunosuppression capacity of the mesenchymal stem cells is improved, the angiogenesis capacity of the mesenchymal stem cells is reduced, meanwhile, by releasing the glucocorticoid medicine at a low dosage, the side effect of single administration is avoided, M2 type macrophage polarization is induced, the inflammatory state of cartilage cells is improved, and the effect of treating the cartilage cells is achieved. The curative effect of the mesenchymal stem cells on osteoarthritis is improved in multiple aspects, and the mesenchymal stem cells are proved in animal bodies. The drug-guided anti-inflammatory enhanced mesenchymal stem cell preparation provides a new thought for the treatment of osteoarthritis.
Owner:THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL UNIV

Portable animal body component analyzer

The invention relates to the technical field of animal body component detection, and provides a portable animal body component analyzer, which comprises a data acquisition module, a data processing module, an analysis module, a data processing module, an analysis module and an analysis module, wherein the data acquisition module is responsible for acquiring multi-frequency bioelectrical impedance data and near infrared spectrum data of domesticated pets; the data processing module is used for carrying out noise filtering, dynamic baseline correction and normalization processing on the collected original data; the algorithm analysis module uses a variety inference and dynamic correction method to correct data errors, extracts body fat distribution, tissue metabolism and body fluid distribution characteristics through a multi-modal data fusion method, and calculates growth and development health scores through an integrated learning supervision model; the database management module stores individual information, appearance characteristics, measurement data and analysis results, and supports data query and backtracking; the user interface is used for inputting animal information and hair states and displaying analysis results, variety similarity, body composition change trends and health scores.
Owner:SHENZHEN YUNTIANKAI SMART MEDICAL TECHNOLOGY CO LTD

Construction method of myocardial ischemia reperfusion injury model

ActiveCN120323405AAnimal husbandryVascular obstructionCoronary arteries
The invention relates to a method for constructing a myocardial ischemia reperfusion injury model, which comprises the following steps of: inserting a vascular occlusion body into a blood vessel of a target mouse, sending the vascular occlusion body to a coronary artery position where vascular occlusion is to be formed, and blocking the coronary artery position where vascular occlusion is to be formed by adopting the vascular occlusion body, the vascular occlusion body is partially or completely made of biodegradable materials, and myocardial ischemia reperfusion injury is simulated through degradation and penetration of the vascular occlusion body in a target mouse body. The vascular occlusion body is prepared from the biodegradable material, the biodegradable material can be automatically degraded in an animal body, myocardial ischemia reperfusion can be simulated without additional operation, and myocardial ischemia reperfusion can be simulated by setting different thicknesses of the degradable part of the vascular occlusion body. The coronary artery ischemia reperfusion time is accurately controlled, and the controllability of the reperfusion time is improved, so that the disease progress of myocardial ischemia / acute myocardial infarction of a human body and reperfusion injury are accurately simulated.
Owner:INST OF ACUPUNCTURE & MOXIBUSTION CHINA ACADEMY OF CHINESE MEDICAL SCI

Closed-loop neuromodulation / neurostimulation system for enabling a body function and / or treatment of a body condition of a mammal

PCT designated stage expiredWO2025045959A1Internal electrodesExternal electrodesAutonomic functionPhysical medicine and rehabilitation
The present invention relates to a system (100), especially a closed-loop system, for planning and / or providing neurostimulation / neuromodulation for enabling a body function, especially a motor function and / or autonomic function, and / or treatment of a body condition of a mammal, especially a human patient (P).
Owner:ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Animal body state monitoring method and system based on implantable chip

The invention relates to the technical field of animal body state warning, and discloses an animal body state monitoring method and system based on an implantable chip, and the method comprises the steps: setting a receiving device which is used for obtaining the monitoring data of a monitoring chip in an animal body; acquiring the species type of the animal, and determining the preset body data of the animal according to the species type. According to the relation between the monitoring data and preset body data, whether health assessment is conducted on the animal or not is determined, according to the relation between the health assessment value and a preset health assessment value, whether alarm information is sent or not is determined, and when the health assessment value is lower than the preset health assessment value, the alarm information is sent according to the relation between the health assessment value and the preset health assessment value. And determining the sent alarm information, and determining the alarm level of the alarm information. According to the invention, the health state of the animal is automatically judged according to the actual monitoring data, and the grading alarm is accurately triggered when the potential health problem is found.
Owner:共济润道人工智能科技(上海)有限公司

Phytobacterium plantarum DACNJS22 and application thereof in preventing / relieving / treating biological metabolic toxicity of benzopyrene

The invention discloses a plant lactobacillus DACNJS22 strain and application thereof in preventing / relieving / treating biological metabolic toxicity of benzopyrene. The lactobacillus plantarum DACNJS22 is preserved in the China Center for Type Culture Collection, and the preservation number of the lactobacillus plantarum DACNJS22 is CCTCC (China Center for Type Culture Collection) NO: M20241957. The plant lactobacillus DACNJS22 disclosed by the invention can be used for efficiently reducing in-vivo bioconversion of benzopyrene into a key carcinogen (benzo (a) pyrene-7, 8-dihydro-diol-9, 10-epoxide) by inhibiting the expression level of cytochrome P450 family genes, and can be used for reducing the biological metabolic toxicity of benzopyrene from the source, so that the application of the plant lactobacillus DACNJS22 in the field of bioconversion of benzopyrene into the key carcinogen is realized. The intake of benzopyrene-polluted food and the damage of benzopyrene exposed to the environment to animal bodies or human bodies can be reduced; the compound can effectively prevent and / or relieve and / or treat tissue and organ injuries caused by oral exposure of benzopyrene and related cognitive diseases.
Owner:SOUTHWEST UNIV

Targeting PARP nuclide probe and preparation method and application thereof

The invention relates to the technical field of nuclide probes, and discloses a targeted PARP nuclide probe and a preparation method and application thereof, and the targeted PARP nuclide probe comprises a radionuclide labeled compound as shown in formula I; the targeted PARP nuclide probe provided by the invention can be used as a diagnosis and treatment reagent to be applied to tumors with high PARP protein expression in human or animal bodies, and is especially suitable for tumor imaging and radionuclide treatment; animal experiments show that the nuclide probe has a high tumor / muscle uptake ratio and shows good application potential. Formula I.
Owner:NANJING NUOYUAN MEDICAL DEVICES CO LTD

Bacillus amyloliquefaciens H-6 and its application in the preparation of a medicament for treating or preventing porcine reproductive and respiratory syndrome virus infection

The present invention belongs to the technical field of antiviral microecological preparations for livestock and poultry, and specifically relates to Bacillus amyloliquefaciens H-6 and its application in the preparation of a medicament for treating or preventing porcine reproductive and respiratory syndrome virus (PRRSV) infection. The preservation number of the said Bacillus amyloliquefaciens is CCTCC NO: M 20242740. This strain can reduce the infection activity of PRRSV cells, inhibit the invasion and infection of PRRSV to cells, and reduce the proliferation of the virus on cells. The anti-infection research at the cell level and the animal body level shows that this strain has a significant anti-PRRSV effect both in vivo and in vitro, can reduce the proliferation of the virus in pigs, reduce the damage of PRRSV infection to lung tissues and organs, effectively control the adverse effects caused by PRRSV infection to the body, and can weaken the clinical symptoms of pigs during PRRSV infection, and can be used for preventing and controlling the occurrence of porcine reproductive and respiratory syndrome.
Owner:HUAZHONG AGRI UNIV +1