23 results about "On cells" patented technology

This application proposes a random access method, user equipment, and storage medium based on cell handover. The method includes: responding to receiving a handover command from a source cell, parsing PRACH configuration information about the target cell from the handover command; detecting a synchronization signal and completing cell synchronization based on the synchronization signal; responding to completing cell synchronization, i.e., sending a preamble sequence, specifically sending the preamble sequence for the first time in the current system frame and for the second time in the next system frame; setting an enlarged first RAR listening window based on the PRACH configuration information; and receiving a RAR from the target cell based on the first RAR listening window, and performing corresponding operations according to the random access type upon receiving the RAR. Based on this, this application eliminates the need to wait for successful decoding of the MIB, thus improving the latency of random access during cell handover and increasing access efficiency.

This invention provides a dry ice transport insulated box for cell products, belonging to the technical field of transport boxes. It includes a box body and lid secured by latches. Inside the box, partitions separate storage compartments for cryopreservation bags, cryopreservation tubes, and dry ice. The dry ice storage compartments are located around the cryopreservation bag and cryopreservation tube storage compartments. Two thermometers are fixed to the side of the box body, with their probes extending into the cryopreservation bag and cryopreservation tube storage compartments respectively, allowing real-time monitoring of the box's internal temperature. The cryopreservation bag storage compartment is used to store strip-shaped cryopreservation boxes containing cryopreservation bags, while the cryopreservation tube storage compartment is used to store square cryopreservation boxes containing cryopreservation tubes. This invention isolates the storage compartments for each cell, preventing collisions and impacts on cell quality stability during transport.

Methods, systems, and devices for wireless communication are described that provide for cell selection or reselection at a user equipment (UE) based on cell selection preference criteria of the UE. The UE may receive a set of cell selection criteria that provides a priority order for cell selection based on one or more cell features, cell types, or combinations thereof. The UE, based on one or more signal measurements of available cells and the cell selection criteria, may select one of the available cells for communications. The UE may also maintain a feature cell database in which a number of cells and an associated feature mask may be stored and used to identify cells having features or types associated with the cell selection criteria for use in cell prioritization. Cell selection criteria may be used for cell selection / reselection procedures, mobility procedures, or any combinations thereof.

The application belongs to the field of stem cell biology and relates to a culture method of a 3D nerve immune organoid containing microglia cells, which comprises the following steps: S1, inducing induced pluripotent stem cells in ectoderm direction and mesoderm direction respectively to obtain nerve-like embryoid bodies and yolk sac-like embryoid bodies; S2, culturing the nerve-like embryoid bodies to make them differentiate into nerves to obtain nerve ring structures, re-digesting the nerve ring structures to obtain nerve progenitor cell single cells, and culturing the yolk sac-like embryoid bodies to make them generate macrophage progenitor cells; and S3, fusing the nerve progenitor cell single cells and the macrophage progenitor cells and continuing to culture to form the 3D nerve immune organoid containing microglia cells. The brain-like organoid of the application can realize the following functions: exploring the control of microglia cells on the proportion of progenitor cells in the development stage, the change of phagocytosis, the control on the number of mature neurons, the influence on cell proliferation and apoptosis, and simultaneously accepting external stimulation and making corresponding functional stress changes.

The utility model discloses a cell culture well plate that reduces impact force relates to cell culture technical field, including cell culture plate, be provided with injection liquid structure on the cell culture plate, and injection liquid structure includes multiple culture wells and injection liquid hole, and culture well and injection liquid hole all are set up on cell culture plate, and culture well and injection liquid hole are through, and the top of cell culture plate is provided with sealing cover, and the diameter of injection liquid hole is one fifth of culture well diameter, and injection liquid hole and culture well hole neck place are through, and the corner of sealing cover and cell culture plate is provided with mark groove, and a plurality of sealing grooves are seted up on sealing cover and are fixedly connected with lug, and the edge of sealing cover is provided with sealing washer, through being provided with injection liquid structure, the injection liquid hole in injection liquid structure can avoid culture liquid to directly drop in culture well, avoid the cell in culture well inside to cause impact force and vibration, avoid the normal growth of cell.

This application discloses a communication method and apparatus, relating to the field of communication technology, for reducing access latency of RedCap terminals. The method includes: obtaining a first cell list; determining the cell order of the first cell list based on cell information; and performing cell search or cell reselection based on the cell order. The first cell list is either a cell search list or a cell reselection list, and the cell information includes at least one of energy, signal-to-noise ratio (SNR), RedCap capability, bandwidth, or cell type. Compared to simply sorting cells in the first cell list based on energy and SNR, this solution additionally considers RedCap capability, bandwidth, and cell type during the cell sorting process. The RedCap terminal can use RedCap capability, bandwidth, and cell type to prioritize cells in the first cell list that are eligible for access, thereby enabling it to use cells at the top of the first cell list to complete access during cell search or reselection, thus reducing cell access latency.

The application provides a content extraction method based on cell membrane capacitance change, and belongs to the field of cell-level micromanipulation technology, and comprises the following steps: S1, a change relationship between cell membrane capacitance and cell membrane surface area is established; S2, a change relationship between cell membrane surface area and volume is approximately established; S3, high-resistance sealing and membrane rupture of cells are completed, constant voltage cell content extraction operation is performed, and cell membrane capacitance values in the extraction process are obtained in real time through capacitance fitting; S4, content extraction amount is estimated; S5, actual cytoplasm extraction amount is calculated based on a rotary L-shaped electrode, the relationship model established in S2 is corrected, and finally, quantitative extraction of cell contents is realized. The application utilizes an electrical model of cell membrane capacitance, realizes real-time feedback of cell content extraction amount, realizes quantitative control of content extraction, can realize a cytoplasm extraction success rate of 62.5% in the case of a whole cell patch clamp structure, and the average cytoplasm extraction amount control error is less than 6% of the total cell volume.

The application discloses a cell occlusion relationship judgment method based on cell boundary junction point types. The method comprises the following steps: performing instance segmentation on a cell microscopic image and extracting a cell boundary; detecting a cell occlusion junction point based on the cell boundary, and classifying the junction point into a cell T-shaped occlusion point, a cell Y-shaped converging point or a cell X-shaped crossing point according to the direction distribution of the boundary line segment; for the cell T-shaped occlusion point, a through long side and a terminal short side are identified according to a geometric extension feature; for the cell X-shaped crossing point, a through long side score is calculated based on image features such as edge intensity, stability and symmetry continuity to perform disambiguation; a cell occlusion relationship graph is constructed with each cell as a node and an occlusion direction as a directed edge, and a directed acyclic graph is obtained through loop resolution. The method can stably distinguish contact and occlusion under the condition that the cell boundary is fuzzy and the cell morphology is variable, and realizes complete occlusion relationship judgment from local junction to global ordering.

A terminal according to one aspect of the present disclosure includes a receiving section that receives a MAC CE (MAC Control Element) including cell switching indication information on cell switching from a serving cell to a candidate cell, and a control section that controls, based on the cell switching indication information, a configuration of a window or a timer for switching from the serving cell to the candidate cell, and operation after the cell switching. The control section controls the window or the timer, based on a MAC reset configuration indicating the operation after the cell switching.

The invention provides an automatic parallel culture method, system and equipment of cell parallel reaction equipment, and relates to the field of cell culture and biological reaction process control, and the method comprises the following steps: initializing culture parameters of a plurality of reaction tanks; in the culture process, carrying out on-line or quasi-on-line detection on the cell concentration, dissolved oxygen, pH and temperature in the reaction tank; based on a detection result, calculating a liquid change strategy parameter and / or a gas adjustment parameter of each reaction tank by the control system; according to a calculation result, independently executing liquid change operation and / or gas flow regulation operation on each reaction tank through automatic equipment; by repeating the steps, automatic, parallel and continuous culture of the multiple reaction tanks is realized. According to the invention, a special cell interception device is not needed, high-throughput, low-cost and full-automatic continuous culture can be realized under the condition of small volume, the reactor culture representativeness and high-throughput screening efficiency are both realized, and the method is suitable for application scenes such as cell amplification, differentiation culture and process optimization.

The application discloses a kind of for sheep MSTN And SOCS2 The sgRNA of gene cytosine base editing and application thereof, the sgRNA includes nucleotide such as any one or several of SEQ ID NO.1~4.This application is respectively designed sgRNA guide sequence for sheep MSTN And SOCS2 Gene, introduce stop codon in target site using CBE system, select sgRNA guide sequence and its combination from which can efficiently target sheep MSTN And SOCS2 Gene, carry out gene editing efficiency verification on cell, and successfully obtain MSTN And SOCS2 Double gene editing goat by prokaryotic embryo microinjection technology, and gene editing sheep shows muscle fiber thickening, and fast growth rate.This application establishes a set of efficient, precise double gene editing technology system, provides key breeding material and technical support for quickly cultivating muscle developed, fast growth meat sheep new variety.

This invention discloses a tissue culture chamber, comprising an inner chamber, an outer ring, and an outer ring connecting portion. The inner chamber includes an inner chamber wall and an inner bottom, with the inner bottom disposed within the cavity formed by the inner chamber wall. A central hole is provided on the inner bottom, and inner bottom leakage holes are distributed on the inner bottom around the central hole. The inner chamber wall includes a top ring and inner chamber pillars circumferentially distributed at the bottom of the top ring. The outer ring is disposed on the outer side of the inner chamber, and the outer ring is connected to each of the inner chamber pillars through the outer ring connecting portion. The tissue culture chamber of this invention can stably support cultured tissues on cell culture plates or cell culture dishes, is convenient and quick to use, and can be reused multiple times to reduce costs.

The present disclosure relates to UE measurement and measurement reporting of serving cells, and configuration for cell measurement and reporting to enable fast serving cell change during UE mobility within lower network layers, such as layer-1 or layer-2 of a wireless communication protocol stack. The present disclosure further relates to signaling procedures associated with fast serving cell change for a UE triggered by the network based on cell measurement and reporting, and various lower layer configurations and operations for enabling actual fast serving cell change at and for the UE.

The present invention relates to a method (100) for setting an electrolyzer.The method (100) comprises:determining (101) a plurality of state characteristic values of a cell stack of the electrolyzer based on cell voltages determined for various operating temperatures of the cell stack at a predefined operating point,determining (103) at least one curve (201, 203, 205) of the state characteristic values over various operating temperatures for a predefined service life,selecting (105) the operating temperature at which the curve (201, 203, 205) of the state characteristic values is at a maximum,setting (107) the selected operating temperature for operating the electrolyzer.

This utility model discloses a cell culture plate, relating to the field of cell culture technology. It includes a base plate with multiple culture tubes evenly distributed and connected to its upper end. A shock-absorbing and buffering mechanism is provided at the lower end of the base plate. This mechanism includes: a flexible shock-absorbing column array, composed of multiple columnar structures made of highly elastic silicone material, evenly distributed and connected to the lower end of the base plate; and shock-absorbing airbags, connected below the flexible shock-absorbing column array, composed of multiple interconnected, elastic micro-airbags. This utility model has a reasonable design structure, capable of buffering and absorbing vibrations from multiple dimensions. It can effectively cope with vibrations of different frequencies and intensities, improving the shock absorption and buffering capabilities of the cell culture plate, effectively reducing the interference of external vibrations on cells, ensuring cell growth in a stable environment, and improving the accuracy and reliability of experimental data.

Embodiments of the present application relate to the technical field of communications, and discloses a communication method and apparatus, used for improving the service continuity of RedCap terminals. The method comprises: determining, in an idle state, whether at least one NR neighbor cell of a currently camped-on cell supports RedCap or eRedCap; and when none of the at least one NR neighbor cell supports RedCap or eRedCap, reporting, in a connected state, to a first network device a first indication indicating that RedCap or eRedCap is not supported, wherein the first network device is a network device corresponding to the currently camped-on cell. In the present application, when none of NR neighbor cells of the currently camped‑on cell supports RedCap, a RedCap terminal will report a non-RedCap capability to a network device corresponding to the currently camped-on cell, so that the RedCap terminal can switch, as a non‑RedCap terminal, to an NR cell that does not support RedCap, and works normally as a non-RedCap terminal in the NR cell that does not support RedCap. Thus, the RedCap terminal is prevented from switching as a RedCap terminal to an NR cell that does not support RedCap, which would cause service interruption due to the inability to operate normally, thereby improving the service continuity of the RedCap terminal.

The present disclosure relates to an electronic device, a communication method and a storage medium in a wireless communication system. There is provided an electronic device on user side, comprising a processing circuitry configured to: based on cell pre-configuration information, measure beams transmitted by a serving cell and at least one non-serving cell; in response to a predefined measurement-based event, send a beam report including at least L1 measurements and identification information for one or more beams of one or more non-serving cells to the serving cell via L1 or L2 signaling; determine an activated beam of the one or more beams; and set a non-serving cell associated with the activated beam as a serving cell.

This invention belongs to the field of biomedical technology, specifically relating to a method and kit for improving the sensitivity and specificity of circulating tumor cell (CTC) detection. The method first treats anticoagulated blood with erythrocyte lysis buffer, centrifuges to obtain a cell suspension (including leukocytes and circulating tumor cells); then, a radiosensitizer is added and the suspension is irradiated; next, single-cell gel electrophoresis is used to detect the degree of DNA damage in the test cells; finally, leukocytes and tumor cells are distinguished based on cell morphology using a fluorescence microscope or fluorescence scanner. This invention is the first to detect the number and type of circulating tumor cells (CTCs) in peripheral blood based on ionizing radiation and radiosensitization effects, according to the degree of DNA damage in tumor cells. Compared with existing technologies, this detection method and kit are not only simple and rapid, but also significantly improve detection sensitivity and specificity. Furthermore, it is independent of the physical properties of cells and tumor cell surface markers, requires a small sample volume, is highly versatile, and can detect CTCs in different types of solid tumors.

This invention discloses a cell culture chamber with a low-intensity pulsed ultrasound environment, belonging to the field of biomedical engineering technology. Targeting scenarios such as rapid culture of specific cells used in cell therapy and scientific research on cell culture in a LIPUS environment, this invention provides a cell culture chamber with a low-intensity pulsed ultrasound environment. By introducing a low-intensity pulsed ultrasound generation module into the cell culture chamber, cells can undergo programmed cell culture in a LIPUS numerically controlled stimulation environment with preset parameters, providing technical support for various clinical cell therapies. It solves the problem of repeatedly removing cell culture dishes to complete ultrasound stimulation protocols, reducing the risk of contamination; it avoids manual operation of ultrasound stimulation, saving manpower, and improves the standardization of interventions, making the process more scientific and standardized.