701 results about "Carbodiimide" patented technology

The invention relates to the technical field of chemical synthesis, and particularly provides a preparation method of a semaglutide side chain, which comprises the following steps: step S1, carrying out reaction on octadecanedioic acid mono-tert-butyl ester and trifluoroacetic acid pentafluorophenyl ester to generate a first intermediate; s2, enabling the first intermediate to react with 1-tert-butyl L-glutamic acid to generate a second intermediate; s3, enabling the second intermediate to react with pentafluorophenyl trifluoroacetate to generate a third intermediate; and S4, carrying out an amidation reaction on the third intermediate and 17-amino-10-oxo-3, 6, 12, 15-tetraoxa-9-aza-heptadecanoic acid, so as to generate a semaglutide side chain, and carrying out an amidation reaction on the third intermediate and 17-amino-10-oxo-3, 6, 12, 15-tetraoxa-9-aza-heptadecanoic acid. According to the preparation method disclosed by the embodiment of the invention, the pentafluorophenyl trifluoroacetate is used as the condensation reagent for two times to activate the carboxylic acid, and the amidation reaction is carried out for two times to construct the amido bond after each activation, so that compared with the traditional carbodiimide and urea positive ion type condensation reagent, the chiral racemization in the condensation process can be effectively avoided, and the yield of the product is improved. The condensation chiral racemization impurity can be lower than 0.3%.

The invention discloses a preparation method of a cell inflammatory factor adsorbent, which comprises the following steps: mixing styrene, divinyl benzene and hydroxyethyl acrylate, and adding a pore-foaming agent and mesoporous SiO2 nano powder to prepare a porous microsphere carrier; the preparation method comprises the following steps: mixing chitosan and poly (N-isopropylacrylamide) in an acetic acid solution to obtain a temperature-sensitive chitosan hydrogel precursor solution; the preparation method comprises the following steps: activating the surface of a porous microsphere carrier by using 1-ethyl-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, mixing the activated porous microsphere carrier and a temperature-sensitive chitosan hydrogel precursor solution to obtain a water phase, and assembling, washing and drying in an oil phase to obtain the cell inflammatory factor adsorbent. Through the design of the core-shell structure and the addition of the mesoporous SiO2 nano powder, the temperature response characteristic and the recyclable characteristic are given to the cell inflammatory factor adsorbent, the adsorption capacity of cell factors is also improved, and a new solution is provided for physical adsorption of the cell inflammatory factors.

The invention relates to the field of zipper processing, in particular to a processing method of a fluoride-free DWR waterproof zipper, which sequentially adopts four steps of pretreatment, padding treatment, drying treatment and heat treatment to carry out waterproof processing on the zipper, the fluorine-free DWR waterproof zipper prepared by matching paraffin, polyether modified silicone oil, carbodiimide, nano silicon dioxide dispersion liquid, fatty alcohol-polyoxyethylene ether and diethylene glycol monobutyl ether has the following advantages that 1, the fluorine-free DWR waterproof zipper meets the limitation requirements of Europe and America regulations and various standards on fluorine element, 2, the waterproof grade meets the grade 4.5 or above of standards such as AATCC / ISO / GB / T and the like, and the fluorine-free DWR waterproof zipper has a good waterproof effect. 3, the washing resistance can reach more than 20 times of washing and drying tests; 4, the phenomenon of white grasping in the market is avoided; and 5, the anti-siphon performance can reach 10H without climbing.

The invention provides a preparation method of NMN nano microspheres with high stability, and belongs to the technical field of NMN. The preparation method comprises the steps of NMN pretreatment, primary microsphere preparation, functional microsphere preparation and mixing. The preparation method of the primary microspheres comprises the following steps: adding epsilon-polylysine and glutathione into an ethanol solution, uniformly stirring, adding 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, and stirring for 28-32 minutes to obtain a mixed solution; adding the pretreated NMN solution into the chitosan solution, then adding the mixed solution, and carrying out heat preservation at 44-50 DEG C for 2.8-3.2 h to obtain primary microspheres; the NMN nano-microsphere prepared by the method disclosed by the invention is good in stability and good in slow release performance.

The invention relates to the technical field of polymethacrylimide foam, in particular to polymethacrylimide wave-absorbing foam and a preparation method thereof. The high-temperature-resistant acrylic resin is prepared from the following raw materials in parts by weight: 55 to 60 parts of methacrylic acid, 45 to 55 parts of methacrylonitrile, 5 to 8 parts of 1-amino octadecane, 0.3 to 0.6 part of N-acrylamide, 0.4 to 0.7 part of N-hydroxysuccinimide ester, 0.5 to 1.2 parts of carbodiimide, 4 to 7 parts of tridecyl methacrylate, 2 to 8 parts of functional filler, 0.35 to 0.40 part of initiator, 0.6 to 0.8 part of foaming agent, 12 to 15 parts of cross-linking agent and 8 to 12 parts of absorbent. 21-35 parts of modified cellulose, 12-25 parts of a biomass-based additive, and 5-18 parts of a dispersant. The prepared polymethacrylimide wave-absorbing foam is relatively good in mechanical property, and shows excellent chemical stability under the conditions of room temperature and extremely low temperature.

The invention relates to the technical field of road crack repairing materials, in particular to a high-strength polyurethane-based road crack repairing material and a preparation method thereof. The composite material is prepared from the following components in parts by weight: 5 to 10 parts of 1, 4-butanediol, 3 to 8 parts of modified nano silicon dioxide, 10 to 20 parts of superfine calcium carbonate, 8 to 12 parts of chopped basalt fiber, 0.5 to 2 parts of 2-(2H-benzotriazole-2-yl)-4, 6-di-tert-pentylphenol, 0.3 to 1.5 parts of carbodiimide and 0.3 to 0.8 part of organic tin-amine composite catalyst. The mechanical strength and the temperature resistance of the material are remarkably improved through a rigid annular structure of dicyclohexylmethane diisocyanate, the material is endowed with elasticity and deformation resistance through a flexible chain segment of polyester polyol, and a repairing layer can bear load impact and can adapt to crack expansion deformation through the synergistic effect of dicyclohexylmethane diisocyanate and polyester polyol; the composite action of the fibers and the filler can disperse stress concentration, reduce the risk of secondary cracking caused by temperature shrinkage or load, and realize long-term stability of crack repair.

The invention provides an antistatic polypropylene material as well as a preparation method and application thereof, and belongs to the technical field of polypropylene materials. The preparation method comprises the following steps: modifying graphene, preparing a graphene / titanium dioxide compound, reacting, and performing extrusion molding. The method comprises the following reaction steps: putting a functionalized graphene / titanium dioxide compound into a reaction container, introducing N, N-dimethylformamide, uniformly stirring, adding modified graphene, dicyclohexylcarbodiimide and 4-dimethylaminopyridine, heating to 73-77 DEG C, carrying out ultrasonic treatment, and after ultrasonic treatment is finished, carrying out heat preservation stirring for 1.8-2.2 hours to obtain the graphene / titanium dioxide composite material. Then heating to 116-123 DEG C at the speed of 1.7-2.3 DEG C / min, stirring for 1.8-2.2 hours while keeping the temperature, after stirring is finished, filtering, washing, freeze-drying, and naturally recovering to room temperature, so as to obtain a graphene-graphene / titanium dioxide compound; the antistatic polypropylene material prepared by the invention is good in antistatic property, excellent in mechanical property and good in aging resistance.

The invention discloses a high-temperature-sintered graining ink as well as a preparation method and application of the high-temperature-sintered graining ink. The invention discloses high-temperature sintered pattern making ink. The ink comprises a component 1, a component 2 and a component 3, wherein the component 1 is prepared from the following raw materials in parts by mass: 30 to 50 parts of waterborne polyurethane resin, 1 to 5 parts of alcohol, 3 to 8 parts of nonionic polyurethane associated thickener, 1 to 5 parts of hand feeling agent, 0.5 to 1 part of wetting agent, 0.5 to 1 part of defoaming agent, 10 to 20 parts of waterborne nano color paste and the balance of deionized water; the component 2 is prepared from the following raw materials in parts by mass: 70 to 80 parts of hydrophilic isocyanate and 20 to 30 parts of propylene glycol methyl ether acetate; and the component 3 is polycarbodiimide. According to the water-based ink, carbodiimide and hydrophilic isocyanate are innovatively matched for use, use of a toxic curing agent aziridine is avoided, and the water-based ink does not contain toxic substances, is small in harm to human bodies and the environment, and meanwhile is high in adhesive force and better in stain resistance and wear resistance.

An adhesive composition (100) comprises: a polyester resin (A) that includes an ester bond which bonds repeating units together and one or more functional groups selected from the group consisting of carboxy groups and carboxylic acid anhydride structures; an epoxy compound (B) in the amount of 1-50 parts by mass with respect to 100 parts by mass of the polyester resin (A); and a cyclic carbodiimide (C) in the amount of 0.1-20 parts by mass with respect to 100 parts by mass of the polyester resin (A).

The invention discloses a synthesis method of oxyalkyl isourea and application of the oxyalkyl isourea as a free radical alkylation reagent. According to the synthesis method, cheap and rich alcohol compounds and carbodiimide are used as raw materials, oxygen alkyl isourea is synthesized in one step under the mild condition of metal catalysis, the synthesis process is simple and convenient, the yield is high, and hectogram-level large-scale preparation can be achieved. The synthesized oxyalkyl isourea can be used as a free radical alkylation reagent to be applied to a coupling reaction of metal catalysis, so that different alkylate products rich in saturated carbon sequence structures are prepared, and the method has a good application prospect.

The invention relates to the technical field of medical materials, in particular to a self-lubricating PEBAX / TPU material suitable for a medical catheter and a preparation process of the self-lubricating PEBAX / TPU material. 8-15 parts of a self-lubricating modified material; 1.5 to 3 parts of an antioxidant complexing agent; and 3-5 parts of a compatilizer. According to the self-lubricating PEBAX / TPU material, fluorocarbon chains are enriched on the surface to form a long-acting low-friction layer through fluorinated polyethylene and hydrophobic nano silicon dioxide, an external coating is not needed, an antioxidant Irganox 1010 and carbodiimide synergistically inhibit oxidation and hydrolysis, the chemical stability is remarkably improved, the compatibility of PEBAX / TPU is improved through maleic anhydride grafted POE, and the self-lubricating PEBAX / TPU material has the advantages that the self-lubricating performance is good; the rigid gradient of the conduit is optimized by combining a multi-layer co-extrusion process, the protein adsorption resistance of the surface is further enhanced through plasma treatment and perfluorosilane grafting, the integrity of the material is guaranteed through accurately controlled low-temperature extrusion and low-dose gamma sterilization, and the material is more stable and reliable while the biological safety is maintained. The synergistic improvement of the lubrication durability, the mechanical property and the aging resistance is realized.

The invention belongs to the technical field of high polymer materials, and discloses a two-component polyurethane pouring sealant and a preparation method thereof.The two-component polyurethane pouring sealant comprises a component A and a component B. The component A comprises, by weight, 40-60 parts of bio-based polyether polyol, 10-15 parts of boron nitride nanosheets, 5-10 parts of graphene modified epoxy resin, 1-3 parts of a silane coupling agent and 0.5-1.5 parts of a supercritical fluid foaming agent; the component B is prepared from 30 to 50 parts of carbodiimide modified MDI (methylene diphenyl diisocyanate), 10 to 20 parts of dendritic polyurethane cross-linking agent and 2 to 5 parts of nano aluminum hydroxide filler; the mixing ratio of the component A to the component B is (2-3): 1; the invention aims to provide the two-component polyurethane pouring sealant and the preparation method thereof, and through material innovation and process integration, the two-component polyurethane pouring sealant which is high in heat conductivity, environment-friendly, weather-resistant and low in internal stress is provided.

The invention belongs to the technical field of probiotic protection, and discloses a preparation method and application of probiotic-loaded sulfydryl hyaluronic acid-based hydrogel, sulfydryl hyaluronic acid is prepared by taking cysteamine hydrochloride as a substrate, and connection of L-glutamine is further catalyzed through a cross-linking agent, so that the sulfydryl hyaluronic acid-based hydrogel is obtained. The cross-linking agent is a mixture of N-hydroxysuccinimide and 1-ethyl-(3-dimethylaminopropyl) carbodiimide or a mixture of N-hydroxysuccinimide and 1-hydroxybenzotriazole (HOBT), and the cross-linking agent is a mixture of N-hydroxysuccinimide and 1-ethyl-(3-dimethylaminopropyl) carbodiimide and 1-hydroxybenzotriazole (HOBT). The hydrogel prepared by the preparation method disclosed by the invention is used as a probiotic carrier, so that the influence of complex gastrointestinal tracts is effectively resisted, the hydrogel accurately reaches an intestinal injury part and is split, and the targeted intestinal controllable release of probiotics is realized; meanwhile, the L-glutamine is introduced and has a synergistic effect with the probiotics to relieve specific intestinal diseases, so that the L-glutamine can be used as a probiotic supplement for the specific intestinal diseases.

The preparation method comprises the following steps: by taking natural chitosan, epsilon-polylysine and polyphenol as raw materials, firstly, respectively preparing polyphenol modified chitosan and carboxyphenylboronic acid modified polylysine through a carbodiimide coupling method, then, mixing single-component solutions of the polyphenol modified chitosan and the carboxyphenylboronic acid modified polylysine, and then, preparing the antibacterial and antioxidant glycopeptide hydrogel based on the polyphenol. And the antibacterial and antioxidant glycopeptide hydrogel is obtained by virtue of the synergistic effect of the phenolic hydroxyl group-boric acid group dynamic bond and the amino group-carboxyl group. The hydrogel disclosed by the invention has broad-spectrum antibacterial property and glucose response oxidation resistance, has self-healing capability and strong wound adhesion, is excellent in biocompatibility and can be naturally degraded; and the process is simple, convenient and controllable, large-scale production is easy to realize, the hydrogel can be used as a wound dressing for treating chronic difficult-to-heal wounds such as diabetes mellitus in a targeting manner, and integrated nursing of antibiosis, antioxidation, wound adhesion and self-repairing is realized.

The invention discloses a preparation method of a new energy battery pack cover plate flame-retardant PP material, and relates to the technical field of polymer flame-retardant materials. The preparation method comprises the following steps: sequentially adding phosphate esterified polypropylene, a maleic anhydride grafted polyolefin elastomer, polyether block amide, modified nano clay, a B-P-triazinyl charring agent, a carbodiimide type anti-hydrolysis agent, a hindered phenol antioxidant, short carbon fibers, polytetrafluoroethylene micro powder and modified hollow glass beads into a mixing mill; and adding the obtained premix into a twin-screw extruder, extruding, pelletizing, and carrying out injection molding to obtain the flame-retardant PP material for the cover plate of the new energy battery pack. The prepared new energy battery pack cover plate flame-retardant PP material has excellent mechanical performance, flame retardance, thermal stability, dimensional stability and antistatic performance, is light in weight, and has wide application prospects in the fields of new energy automobiles, energy storage systems, consumer electronics, aerospace and industrial equipment.

The invention discloses a functional hydrogel microsphere and a preparation method and application thereof, and relates to the technical field of medicines.The preparation method comprises the steps that a hyaluronic acid methacrylic acid precursor solution and an IL-1beta shRNA adenovirus stock solution are mixed to obtain an Ad-atHAMA precursor solution; preparing the Ad (at) HAMA precursor solution through an oil-in-water micro-fluidic technology to obtain an Ad (at) HAMA microsphere; and sequentially adding the Ad (at) HAMA microspheres, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide into a 2-morpholinoethanesulfonic acid buffer solution, carrying out activating treatment, adding E selectin, and incubating to obtain the functionalized hydrogel microspheres. The functionalized hydrogel microspheres can inhibit a related mechanism of acute spinal cord injury pathological progress and promote neural function repair by targeting adsorption of neutrophil to regulate Nets-triggered innate immune inflammation cascade.

The invention relates to the technical field of batteries, in particular to a low-hydrogen-evolution graphene material for a lead-acid battery and a preparation method thereof.The method comprises the steps that firstly, ethidene diamine is grafted to the surface of graphene oxide through a carbodiimide / active ester method, and aminated graphene is obtained; performing heat treatment in a nitrogen / ammonia gas atmosphere to realize nitrogen doping; compounding with titanium dioxide, and carrying out hydrothermal reaction to form a stable structure; then, sequentially grafting imidazolium silane and perfluorodecyl silane to carry out hydrophobic modification; and finally, stabilization and low-temperature re-nitridation curing are carried out through titanium tetrabutoxide. The graphene material prepared by the method endows the battery with excellent performance, and is low in direct-current internal resistance and high in capacity retention ratio.

A lithium supplement and a preparation method therefor, a positive electrode sheet, and a battery. The lithium supplement comprises: a core, wherein the core comprises LiaMbOc, wherein a is 2-6, b is 0-4, c is 1-6, and M comprises at least one of Mg, Al, Si, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Zr, Nb, Mo, Ru, and Sn; and a coating layer, wherein the coating layer at least covers part of the surface of the core, and the coating layer contains at least one of a silazane compound, a siloxane compound, a sulfonic acid silane compound, and a carbodiimide compound.

The invention provides synthesis of a T-2 toxin antigen and preparation and application of a monoclonal antibody. Relates to the technical field of biotoxin detection. The preparation method of the T-2 toxin antigen comprises the following steps: step 1, synthesizing an immunogen T-2-BSA by adopting a carbodiimide method, dissolving 2mg of T-2 adipic acid with 0.5 mL of dimethylformamide, and recording as a solution A; 5 mg of bovine serum albumin and 3 mg of EDC are dissolved with a 2-morpholine ethanesulfonic acid buffer solution with the pH being 5.5, and the solution is marked as a solution B; step 2, under the condition of stirring, dropwise adding the solution A into the solution B, stirring for 18 hours in a dark place at 4 DEG C, then dialyzing for 3 days by using a phosphate buffer solution, changing the solution once a day, centrifuging the dialysate for 10 minutes at 3,500 r / min, and discarding the precipitate; the adipic acid is coupled with the T-2 toxin through a chemical method, and the unique step enriches the structural characteristics of the hapten, so that the prepared T-2 toxin complete antigen is excellent in immune effect, can efficiently excite immune response of an organism, and shows high specificity and sensitivity.

The invention relates to the technical field of removal of carbon dioxide in oil gas, in particular to a preparation method of carbon dioxide PAMAM grafted ionic liquid for oil gas purification. Comprising the following steps: 1) activating carboxyl: dissolving 1-butyl-3-methylimidazole carboxylic acid in a solvent, adding dicyclohexylcarbodiimide and 4-dimethylaminopyridine, and stirring at room temperature to generate active ester; 2) grafting PAMAM: adding PAMAM dendrimer into the solution, and reacting under the protection of nitrogen; and 3) purification: removing the dicyclohexylurea precipitate through centrifugation, and dialyzing the filtrate to remove the unreacted ionic liquid and small molecule byproducts to obtain the PAMAM grafted ionic liquid. The stability and durability of the absorbent are remarkably improved, the CO2 absorption efficiency is improved, the energy consumption of the absorbent per unit mass is reduced, and the preparation method is simple and controllable, mild in reaction condition and easy for large-scale production.

The invention relates to the technical field of resin composite materials, in particular to a layer-adding adhesive film for an FC-BGA packaging carrier plate, a preparation method of the layer-adding adhesive film and an adhesive-coated copper foil. The layer-adding adhesive film is prepared from the following raw materials in parts by mass: 50 to 60 parts of epoxy resin, 180 to 200 parts of inorganic filler, 30 to 36 parts of curing agent, 4 to 6 parts of modified phenoxy resin, 3 to 5 parts of carbodiimide resin and 0.2 to 0.4 part of 4-dimethylaminopyridine. Modified phenoxy resin and carbodiimide resin are added on the basis of main components such as epoxy resin, inorganic filler and a curing agent, meanwhile, 4-dimethylaminopyridine is used as a curing accelerator, and through the synergistic effect of all the components, the dielectric loss angle tangent of a layer-adding adhesive film can be effectively reduced, the glass-transition temperature of a layer-adding adhesive layer is increased, and the bonding strength of the layer-adding adhesive film is improved. Good flame retardance of the layer-adding adhesive film is ensured, and the layer-adding adhesive film is applied to the adhesive-coated copper foil.

The invention is suitable for the technical field of MCA, and provides an MCA / PA6 flame-retardant composite material and a preparation method thereof. Comprising the following components in parts by weight: 50-60 parts of MCA, 15-20 parts of PA6, 15-25 parts of long glass fiber, 3-8 parts of metal hydroxide, 0.5-1.5 parts of titanium dioxide, 0.3-0.6 part of an antioxidant, 1-2 parts of nano silicon dioxide, 1-3 parts of zinc molybdate, 2-5 parts of aluminum hypophosphite, 1-2 parts of silicone resin, 0.5-1 part of carbodiimide and 5-8 parts of a toughening agent. The MCA / PA6 flame-retardant composite material disclosed by the invention combines the flame-retardant property of MCA and the excellent physical property of PA6, so that the flame-retardant property of the material is remarkably improved, and meanwhile, the original characteristics of light weight, good toughness, chemical resistance, good durability and the like of PA6 are maintained. By adding the long glass fiber, the metal hydroxide, the titanium dioxide, the antioxidant, the nano silicon dioxide, the zinc molybdate, the aluminum hypophosphite, the silicone resin, the carbodiimide, the flexibilizer and other components, the strength, the heat resistance and the flame retardant effect of the composite material are further enhanced.

The present invention relates to a microneedle-based transdermal delivery patch fabricated from a hydrogel composed of polyvinyl alcohol (PVA), arginine-modified chitosan, and a crosslinker. The arginine-modified chitosan is prepared by reacting a chitosan solution with an arginine solution preactivated with N-hydroxy succinimide and 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide at a specific pH. The hydrogel's formulation further comprises a PVA concentration ranging from 10% to 12% (w / v). arginine-modified chitosan and PVA solution are mixed in a 1:2 ratio by volume and are crosslinked using trimethyl orthoformate (TMOF). The patch is further loaded with curcumin, with a concentration of 120μg per patch, demonstrating a 70% release over 48 hours in a controlled manner. This invention represents the first application of PVA crosslinked arginine-modified chitosan hydrogel loaded with curcumin specifically for animal wound healing, providing enhanced wound healing and antibacterial efficacy.

The invention discloses a nano-drug delivery system for treating myocardial fibrosis as well as a preparation method and application of the nano-drug delivery system, and belongs to the technical field of biological medicines. According to the system, ZIF-8 is taken as a core carrier, the loading efficiency of pirfenidone is improved through high specific surface area and adjustable aperture, PCM myocardial targeting peptide is covalently coupled on the surface, and the limitation of tissue selectivity is broken through. Through coordination complexation, pi-pi conjugate accumulation and electrostatic interaction synergy, stable drug loading and microenvironment response release are guaranteed; a one-pot method and a carbodiimide method are adopted to wrap PFD and modify PCM on the surface of ZIF-8 to form a nano-drug delivery system; according to the system, the fibrosis process is intervened through multiple mechanisms, the enrichment degree and the acting time of the medicine at the diseased region are improved, the prepared medicine integrates the carrier structure advantage and the targeting peptide function, efficient medicine carrying, precise delivery and controllable release are achieved, a new scheme is provided for myocardial fibrosis treatment, and the system has wide application prospects.

The invention provides a porphyrin functionalized carbon nanotube compound. Medium-tetra (4-carboxyphenyl) porphyrin is covalently connected to the surface of an aminated carbon nanotube through an amido bond to form the compound. Stable amido bond connection is formed through amino-carboxyl condensation, and the bond energy is obviously higher than that of an ester bond. The invention also provides a preparation method of the porphyrin functionalized carbon nanotube compound, which comprises the following steps: carrying out carboxyl activation treatment on the meso-tetra (4-carboxyl phenyl) porphyrin by adopting a catalytic system consisting of N, N '-dicyclohexylcarbodiimide and N-hydroxysuccinimide; the preparation method comprises the following steps: performing ultrasonic treatment on aminated carbon nanotubes in N, N-dimethylformamide, adding the aminated carbon nanotubes into an activated meso-tetra (4-carboxyphenyl) porphyrin solution prepared in the step 1, performing stirring reaction at room temperature, and performing suction filtration and freeze drying to obtain a target product, namely the porphyrin functionalized carbon nanotube compound. A mild room-temperature stirring process is adopted, so that the dependence of a solvothermal method on high-temperature and high-pressure equipment is completely avoided, and the production cost is remarkably reduced.

The invention discloses an alcohol-resistant automobile interior TPO skin, and relates to the technical field of artificial leather. The alcohol-resistant automobile interior TPO skin comprises a coating, a TPO surface layer and a foaming layer from top to bottom, wherein the coating comprises a surface layer and a bottom coating; the surface layer is prepared from the following raw materials in a mass ratio: a matte water-based polycarbonate polyurethane emulsion, a bright water-based polycarbonate polyurethane emulsion, a curing agent, a slipping agent and a defoaming agent in a mass ratio of 3: 1: (0.24-0.48): (0.24-0.4): (0.012-0.016); the bottom coating comprises the following raw materials: waterborne polyurethane resin and a carbodiimide curing agent in a mass ratio of 100: (4-6). The alcohol-resistant automobile interior TPO skin has the effect of good alcohol resistance, and the problem that an existing automobile interior TPO skin is poor in alcohol resistance is solved.

The invention discloses preparation and application of bacteriophage-loaded sericin microgel, and belongs to the technical field of food preservation. The sericin microgel capable of loading the bacteriophage is prepared from a sericin solution extracted by using 1-ethyl-(3-dimethylaminopropyl) carbodiimide (EDC) in combination with a mechanical shearing method and a high-temperature and high-pressure method. The sericin protein microgel loaded with bacteriophage, which is obtained by soaking the microgel into bacteriophage proliferation liquid after freeze-drying, can significantly improve the storage stability of the bacteriophage and can effectively prolong the shelf life of beef, and the preparation method is green, simple and safe, has a wide application prospect, and is suitable for industrial production. Meanwhile, a new field is opened up for efficient application of the bacteriophage.

The invention relates to the technical field of waterproof gas-permeable membranes, in particular to a waterproof gas-permeable membrane with heat preservation performance and a preparation method thereof.The waterproof gas-permeable membrane with the heat preservation performance comprises a bio-based polymer, an ultraviolet light absorber, heat preservation filler, a plasticizer and a cross-linking agent.The bio-based polymer is selected from one or more of polylactic acid (PLA), polyhydroxyalkanoate (PHA) and cellulose ester; the ultraviolet light absorber is a mixture of nano-zinc oxide and nano-titanium dioxide, the thermal insulation filler is a combination of aerogel microspheres and hollow glass beads, the plasticizer is tributyl citrate or acetyl tributyl citrate, the cross-linking agent is a carbodiimide compound, and the filler is a mixture of nano-zinc oxide and nano-titanium dioxide. The materials are subjected to drying, blending, melt extrusion, stretching forming and heat treatment to finally obtain a waterproof breathable film with a heat preservation effect, and meanwhile, the waterproof breathable film also has an ultraviolet-proof function.

An ink set for inkjet textile printing includes an ink and at least one treatment liquid. The ink includes a pigment, a pigment-dispersing agent, and a solvent, the pigment-dispersing agent is a block copolymer including a hydrophilic block A and a hydrophobic block B, at least one of the treatment liquid and the ink contains a crosslinking agent, and the crosslinking agent includes at least one of a vinyl ether compound, an epoxy compound, a carbodiimide compound, an oxazoline compound, an isocyanate compound, and an aziridine compound.

The invention provides a preparation method of dipeptide-2, which comprises the following steps: dissolving (S)-2-((tert-butoxy) amino)-3-methylbutyric acid, N-hydroxysuccinimide and dicyclohexylcarbodiimide in an organic solvent I under the protection of inert atmosphere, reacting at 10-30 DEG C for 8-30 hours, filtering, and concentrating filtrate under reduced pressure until the filtrate is dry to obtain an intermediate 1; controlling the temperature to be-5 DEG C to 5 DEG C, mixing the intermediate 1, L-tryptophan and an organic solvent II, adding an alkaline reagent, reacting at 20-40 DEG C for 12-30 hours after adding, then adding water and ethyl acetate for extraction, retaining an ethyl acetate phase, and concentrating under reduced pressure to be dry to obtain an intermediate 2; dissolving the intermediate 2 in an organic solvent III, adding an acidic reagent I, reacting at 10-30 DEG C for 2-30 hours after the addition is completed, concentrating to dryness, then dissolving in an acidic reagent II, adjusting the pH value to 6-7, finally adding a dipeptide-2 seed crystal, crystallizing, filtering and drying to obtain the dipeptide-2. The purity of the dipeptide-2 prepared by the method is greater than 99%, and the yield is high.