2750 results about "Diamine" patented technology

The invention discloses an arginine decarboxylase diaA enzyme mutant and application thereof in preparation of butanediamine, and belongs to the field of bioengineering. According to the invention, rational charge overturning transformation is simultaneously carried out on a pentamer meridian oligomeric interface and a dimer latitudinal oligomeric interface, so that stable assembly and efficient catalysis of the decamer under the condition of neutral to alkaline pH (7.0-9.0) are realized. Wherein positive charges are introduced into a meridian interface to weaken electrostatic repulsion, and negative charges are introduced into a latitudinal interface to enhance dimer compactness and substrate transfer efficiency. The specific enzyme activity of the representative double mutant AdiAD110K / H736E at pH 8.0 is about 35 times that of a wild type, and the representative double mutant AdiAD110K / H736E keeps a complete decamer state in a pH range of 7.0-9.0. The yield of butanediamine is up to 145.9 g / L under the whole-cell catalysis of the mutant.

The invention relates to a crown ether covalent organic framework material as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving a crown ether monomer and an amino monomer in an o-dichlorobenzene solvent, adding a catalyst acetic acid aqueous solution, and uniformly dispersing to form a reaction solution; the method comprises the following steps: freezing a reaction solution through a liquid nitrogen bath, vacuumizing, filling nitrogen, carrying out a heating reaction, and carrying out post-treatment operations such as washing and drying on a reaction product, so as to obtain the crown ether covalent organic framework material BADT-DB18C6-COF. The crown ether covalent organic framework material is formed by condensation of a crown ether aldehyde monomer and an amino monomer, the crown ether monomer is 4, 4 ', 4' ', 4 '''-(6, 7, 9, 10, 17, 18, 20, 21-octahydrodibenzo [B, K] [1, 4, 7, 10, 13, 16] hexaoxacyclo octadecene-2, 3, 13, 14-tetrayl) tetrabenzaldehyde, and the crown ether monomer is 4, 4 ', 4' ', 4'''-(6, 7, 9, 10, 17, 18, 20, 21-octahydrodibenzo [B, K] [1, 4, 7, 10, 13, 16] hexaoxacyclo octadecene-2, 3, 13, 14-tetrayl) tetrabenzaldehyde. The amino monomer is 4 ', 5'-bis (4-aminophenyl)-[1, 1 ': 2', 1 ''-terphenyl]-4, 4''-diamine. The crown ether covalent organic framework material BADT-DB18C6-COF prepared by the invention is mainly used as an adsorbent, is used for adsorbing and recovering uranium, thorium and americium ions from a solution, shows good adsorption capacity on radionuclides U-238, Th-232 and Am-243, and is particularly suitable for the field of spent fuel post-treatment in the nuclear industry.

The invention discloses a bamboo powder-containing biodegradable plastic for food contact and a preparation method thereof, and relates to the technical field of bio-based materials. The bamboo powder-containing biodegradable plastic for food contact comprises chitosan starch and modified bamboo powder, the chitosan starch is prepared by adding composite chitosan and amino-terminated polyethylene glycol into oxidized corn starch, and the composite chitosan is prepared by grafting chlorogenic acid on the surface of chitosan and then coating succinic anhydride derivatives. The succinic anhydride derivative is prepared from dodecenyl succinic anhydride and 1, 4-butanediamine through a reaction, so that the plastic has the antibacterial property, and meanwhile, the mechanical property is enhanced; the modified bamboo powder is prepared by reacting bamboo powder with a carboxyl-terminated composition, and the carboxyl-terminated composition comprises carboxyl-terminated polylactic acid and carboxyl-terminated polyamide. The toughness of the plastic is enhanced, and the mechanical property of the plastic is further enhanced.

The invention discloses a rational copolymerization strategy for improving the stability of an oligomeric structure of acid-induced high-order oligomeric decarboxylase AdiA in a neutral to alkaline environment and application of the rational copolymerization strategy, and belongs to the field of bioengineering. According to the strategy, rational charge overturning transformation is carried out on a pentamer radial oligomeric interface and a dimer weft-wise oligomeric interface at the same time, and stable assembly and efficient catalysis of a decamer under the condition that the pH value is from 7.0 to 9.0 from neutral to alkaline are achieved. Wherein positive charges are introduced into a meridian interface to weaken electrostatic repulsion, and negative charges are introduced into a latitudinal interface to enhance dimer compactness and substrate transfer efficiency. The specific enzyme activity of the representative double mutant AdiAD471K / E467K / H736E is 45.5 times that of a wild type when the pH value is 8.0, and the representative double mutant AdiAD471K / E467K / H736E keeps a complete decamer state when the pH value is 7.0-9.0. The yield of butanediamine is up to 156.5 g / L by using the mutant to catalyze whole cells.

The invention discloses a high-efficiency lysine decarboxylase mutant and an application of the high-efficiency lysine decarboxylase mutant in synthesis of pentamethylene diamine. A series of mutants including a single mutant (such as N218G, T222V, C244P and the like), a double mutant and a three mutant are obtained by carrying out multi-site mutation on wild type lysine decarboxylase (SEQ ID NO.2) from Klebsiella grimontii. The catalytic efficiency of the mutant is remarkably improved, and the activity of the mutant is improved by 5.0-10.2 times compared with that of a wild type enzyme. According to the method disclosed by the invention, the substrate conversion rate of 99% or above can be realized within 2 hours through an optimized process of constructing an expression vector and a genetically engineered bacterium, inducing expression of lysine decarboxylase and synthesizing 1, 5-pentanediamine by utilizing a whole-cell catalysis technology. Compared with a traditional chemical method and a natural enzyme method, the method disclosed by the invention has the advantages of simplified process, high catalytic efficiency, low production cost and the like, and is suitable for producing bio-based 1, 5-pentamethylene diamine and nylon 56 salt.

The invention discloses a glue solution for a copper-clad plate and a preparation method of the glue solution, and relates to the technical field of copper-clad plates. According to the prepared glue solution for the copper-clad plate, the composite epoxy resin, the curing agent, the accelerant, the solvent, the flexibilizer and the inorganic filler, the composite epoxy resin comprises bisphenol A epoxy resin, epoxy phenyl polysiloxane, itaconic acid polyaryletherketone and hydroxyl-terminated fluorine-containing vinyl polysiloxane, so that the interface bonding force with the copper plate is enhanced; the dielectric constant and the dielectric loss are effectively reduced, the peel strength and the toughness of the material are also remarkably improved, and the toughening agent is modified polyether sulfone microspheres; the modified polyethersulfone microspheres are prepared by coating polyethersulfone microspheres with hexamethylenediamine tetrapropionamide diamine, the hexamethylenediamine tetrapropionamide diamine is prepared by carrying out acylation condensation reaction on hexamethylenediamine tetramethyl propionate and ethylenediamine, and the polyethersulfone microspheres are prepared by carrying out electrostatic spinning on a spinning solution of polyethersulfone and vinylpyridine, so that the peel strength of the glue solution is remarkably improved.

The invention relates to the technical field of dielectric materials, and discloses polyimide, a polyimide film and a preparation method and application thereof, the polyimide is obtained by a polymerization reaction of a dianhydride monomer and a diamine monomer, the diamine monomer comprises a methylene bridging group and a phenyl group with a substituent group, and the methylene bridging group is a phenyl group with a substituent group. The substituent group at least comprises one methyl group. The molecular twisted conformation lock structure provided by the invention not only can improve the tolerance of polyimide, but also can doubly inhibit intrachain and inter-chain charge migration of the dielectric film, so that the dielectric film still has extremely high energy storage density and energy storage efficiency at a service temperature close to a glass-transition temperature.

The invention relates to the technical field of sensors, in particular to a high-sensitivity pressure-temperature dual-mode sensor and a preparation method thereof.The preparation method comprises the steps that a carbon nano tube is subjected to acid treatment and then reacts with a silane coupling agent KH550, and an aminated carbon nano tube is prepared; the method comprises the following steps: carrying out hydrothermal reaction on a phosphorus source and a graphene oxide aqueous solution to prepare phosphorus-doped reduced graphene oxide; the preparation method comprises the following steps: synthesizing Au-Ag heterojunction nano dispersion liquid through an Au nano seed method; mixing the three components and carrying out ultrasonic treatment to obtain mixed dispersion liquid; the preparation method comprises the following steps: modifying a PDMS substrate with KH560 and polyethylene glycol diamine to prepare a modified PDMS substrate; and coating the mixed dispersion liquid on a modified substrate to form a sensitive layer, and preparing an electrode to obtain the sensor. The aminated carbon nanotubes and the phosphorus-doped reduced graphene oxide construct a three-dimensional conductive network, so that high-sensitivity pressure detection is realized; the phosphorus-doped reduced graphene oxide and the Au-Ag heterojunction form a Schottky barrier, so that stable temperature sensing is realized; and the modified PDMS and the sensitive layer are strongly combined to improve the mechanical durability.

The invention relates to the technical field of material preparation, and discloses a polyamide elastomer and a preparation method and application thereof, and the preparation method of the polyamide elastomer comprises the following steps: mixing raw materials, and carrying out amidation reaction to obtain an amide compound; then adding a catalyst B, and carrying out polyesterification reaction to obtain a polyamide elastomer; the raw materials comprise binary acid, diamine, polyether glycol, a catalyst A and water, the reaction temperature of the amidation reaction is 150-180 DEG C, and the addition amount of the water is 20-40% of the total mass of the binary acid, the diamine and the polyether glycol. The polyamide elastomer which is relatively regular in structure and excellent in comprehensive performance can be prepared, the reaction efficiency can be effectively improved, and the preparation method is suitable for industrial large-scale production.

The invention discloses a high-temperature-resistant, bending-resistant and high-flexibility polyimide film for flexible display and a preparation method of the high-temperature-resistant, bending-resistant and high-flexibility polyimide film. According to the polyimide film, by introducing the nano silicon dioxide particles and constructing the porous structure design, the problems that a traditional polyimide film is insufficient in stability in a high-temperature environment, cracks are likely to be generated after bending, and the flexibility is poor are effectively solved. The polyimide film disclosed by the invention is prepared by adopting a diamine monomer and a dianhydride monomer as main raw materials, adding nano silicon dioxide particles, and carrying out solution polymerization, gelation, pore regulation and control and thermal imidization processes. The obtained polyimide film has a micron-sized porous structure, keeps stable at a high temperature of 400 DEG C, does not generate cracks after being bent for 100,000 times, has tensile strength of more than or equal to 150MPa, elongation at break of more than or equal to 25% and light transmittance of more than or equal to 85%, and is suitable for a substrate material of a flexible display device.

The invention discloses a multi-amino absorbent for carbon dioxide capture and a method for capturing carbon dioxide from a gas mixture, and belongs to the technical field of gas separation and carbon capture, utilization and storage. The multi-amino absorbent at least comprises a first component and a second component, wherein the first component is at least one N-hydroxyalkyl-N '-hydroxyalkyl-alkane diamine; the second component is at least one organic amine different from the first component, and the organic amine contains amino groups which are not primary amino groups and does not contain steric hindrance amino groups; and a solvent and optionally an additive. The method for capturing carbon dioxide from a gas mixture includes contacting the polyamino absorbent with a gas mixture containing carbon dioxide, thereby capturing carbon dioxide. The polyamino absorbent disclosed by the invention has the advantages of low carbon dioxide absorption reaction heat in normal-pressure flue gas, high circulating absorption amount, high absorption rate, high desorption rate, low volatility and the like.

The invention provides a preparation method of a self-repairing resin-based composite material based on dynamic bonds. The self-repairing epoxy resin comprises one covalent dynamic bond of a Diels-Alder bond, a disulfide bond or a borate bond, and the preparation method of the self-repairing epoxy resin comprises the following steps: heating epoxy resin to a molten state, adding a curing agent component while stirring, and carrying out a prepolymerization reaction to obtain a prepolymer; the curing agent comprises a rigid diamine curing agent, a dynamic diamine monomer and a flexible chain segment regulator, and the dynamic diamine monomer contains a dynamic covalent bond; and carrying out curing molding on the prepolymer to obtain the self-repairing epoxy resin. And impregnating reinforced fibers or fabrics thereof with the prepared prepolymer, and heating and curing to obtain the self-repairing resin-based composite material. The invention provides a chemical molecule design, dynamic reversible chemical bonds are introduced into a resin matrix, and by constructing the dynamic bonds, the composite material has high performance of a traditional composite material and also has life-like self-healing ability.

The invention discloses a wear-resistant vehicle body film and a preparation method thereof, and relates to the technical field of films. The wear-resistant automobile body film prepared by the invention is prepared from polytetrahydrofuran ether glycol, isophorone diisocyanate, a catalyst, dihydric alcohol quaternary ammonium salt, a functional aid, modified silicon dioxide and a chain extender. The dihydric alcohol quaternary ammonium salt is obtained by reacting N, N '-dihexyl-N, N'-dimethyl propane-1, 3-diamine with monochloroacetone and then condensing with glycerol; the functional additive is obtained by reacting 2-boric acid thiophene-4-methyl acetate with 2, 7-dibromofluorene and then carrying out bromination hydrolysis; the modified silicon dioxide is obtained by reacting pretreated silicon dioxide with melamine and then reacting with sodium hypophosphite. The wear-resistant vehicle body film prepared by the invention has good anti-aging, wear-resistant, antibacterial and flame-retardant properties.

The invention discloses a method for preparing calcium hydroxide slurry with high specific surface area and high pore volume, which comprises the following steps: S1, adding an alcohol reagent into water to obtain a solution A; s2, adding an inorganic salt solution into the solution A, and uniformly mixing to obtain a solution B; s3, a reagent X is added into the solution B, ultrasonic mixing is performed to obtain a solution C, and the reagent X is a mixture of phenol or triethanolamine, ethidene diamine and ethylamine; and S4, adding calcium oxide powder into the solution C, continuously stirring, and reacting to obtain calcium hydroxide slurry. The invention provides a method for preparing calcium hydroxide slurry with high specific surface area and high pore volume, the calcium hydroxide slurry prepared by the method can form calcium hydroxide with high specific surface area and high pore volume when in use, and the method aims to solve the problems of low specific surface area and low pore volume of the existing calcium hydroxide. Therefore, the problem of desulfurization performance inactivation caused by blockage of calcium hydroxide (desulfurizer) pores by generated CaSO3 and CaSO4 in the desulfurization process is avoided.

The invention relates to the field of preparation of polyurethane damping materials, in particular to a preparation method of a repairable polyurethane damping material based on multiple hydrogen bonds and metal coordination. Compared with a traditional damping material, the damping material has a higher damping temperature range and has a good damping effect at the temperature of-20 DEG C to 60 DEG C. Multiple reversible hydrogen bonds are introduced through diamine containing amido bonds, the material is endowed with self-repairing and high mechanical strength, and damping and self-repairing performance is further enhanced through pyridine nitrogen atom metal coordination. Starting from molecular structure design, multiple hydrogen bonds and metal-ligand coordination bonds constructed on a polyurethane molecular main chain play a role in synergistic enhancement, energy can be effectively dissipated through dissociation and recombination of the multiple hydrogen bonds and fracture and association of the metal coordination bonds, and the energy consumption is reduced. The polyurethane material is endowed with excellent damping performance and self-healing capability by the dual dynamic action.

The invention provides an antifouling self-cleaning fluorocarbon finish paint as well as a preparation method and application thereof, and particularly relates to the technical field of special coatings. The antifouling self-cleaning fluorocarbon finish paint is composed of a component A and a component B in a ratio of (80-87): 16, the component A is prepared from the following components in parts by weight: 560 to 580 parts of fluorocarbon resin, 30 to 35 parts of a first solvent, 20 to 40 parts of a second solvent, 180 to 220 parts of titanium dioxide, 90 to 110 parts of filler, 11 to 20 parts of a light stabilizer, 3 to 5 parts of a thickening agent and 13 to 28 parts of an auxiliary agent; the component B comprises the following components in parts by weight: 20-22 parts of fluorocarbon resin, 4-5 parts of a chain extender, 15-20 parts of a diamine curing agent, 15-20 parts of a polyamine curing agent and 25-35 parts of a second solvent. According to the finishing paint, on the basis of enhancing the self-cleaning capability, the weather resistance of a coating is improved, and the aging and damage of the coating are delayed, so that the service life of the coating is prolonged.

The invention relates to a bimolecular modified straw adsorbent as well as a preparation method and application thereof. The preparation method comprises the following steps: cleaning, drying and grinding straws, and sieving by a 100-mesh sieve; adding a polyethylene diamine solution, and carrying out stirring reaction at normal temperature; adding L-cysteine, adjusting the pH value to 4.5-5.5, and continuously stirring to react for 6-10 hours; and filtering, washing and drying to obtain the product. The preparation method has the advantages of simple steps, easily available raw materials and low requirements on equipment; the prepared bimolecular modified straw adsorbent has good removal effect and selectivity on Sb (III) and Sb (V), and is wide in pH value adaptation range. And a new technical means is provided for high-value conversion of straws and removal of antimony in water.

The invention relates to the technical field of aramid fibers, in particular to a heterocyclic aramid fiber and a preparation method thereof.The preparation method comprises the steps that S1, p-phenylenediamine, benzimidazole diamine and terephthaloyl chloride are subjected to a polymerization reaction in an amide solvent, and a polymer stock solution is obtained; s2, the polymer stock solution is subjected to spinning through a spinning nozzle, coagulating bath forming, drafting bath, alkali washing, water bath, drying, hot drafting, oiling and winding into a barrel, and the heterocyclic aramid fiber is obtained. In the step S1, the polymerization reaction temperature is-10 DEG C to 0 DEG C. According to the heterocyclic aramid fiber prepared by the preparation method, the problems of broken filaments, doubled filaments, sticky filaments, broken filaments and the like are obviously improved, the mechanical property is improved, the irregularity is reduced, and the product quality is excellent. The tensile strength of the heterocyclic aramid fiber is 30 to 37 cN / dtex, the elongation at break of the heterocyclic aramid fiber is 3.0 to 4.0 percent, and the elastic modulus of the heterocyclic aramid fiber is 950 to 1150 cN / dtex.

A preparation equipment and a process for a nylon salt solution. The preparation equipment includes a suspension preparation device, a first salt formation reactor and a second salt formation reactor. The suspension preparation device includes a feeding unit, a continuous feeding unit, a high-shear pump and a mixing reactor, the high-shear pump and the mixing reactor are cyclically connected with and in communication with each other through two connecting pipelines; the second salt formation reactor includes a second diamine feed pipe, a third diamine feed pipe, a circulation pipeline of the second salt formation reactor and an online near-infrared monitoring equipment located on the circulation pipeline of the second salt formation reactor.

The invention provides copolymerized flame-retardant nylon containing nitrogen and phosphorus as well as a preparation method and application of the copolymerized flame-retardant nylon. The copolymerized flame-retardant nylon containing nitrogen and phosphorus is formed by copolymerizing a structural unit I and lactam or copolymerizing the structural unit I, diamine and binary acid, the nitrogen and phosphorus-containing copolymerized flame-retardant nylon belongs to a halogen-free flame-retardant environment-friendly high polymer material and is intrinsic flame-retardant nylon, so that the problems of flame retardant migration, compatibility with a base material and the like do not exist, excellent flame-retardant performance can be achieved under the condition of relatively low introduction amount of a flame-retardant structural unit, and meanwhile, excellent mechanical property and spinnability can be kept.

The invention relates to the technical field of metal working fluids, in particular to a degradable environment-friendly vegetable oil-based semi-synthetic cutting fluid and a preparation method thereof. The cutting fluid comprises 20-30 parts of vegetable lubricating oil, 10-20 parts of an alkali storage agent, 2-5 parts of a corrosion inhibitor, 3-5 parts of a coupling agent, 5-8 parts of a surfactant and 6-11 parts of a composite anti-rust agent, the composite anti-rust agent comprises an anti-rust agent A and an anti-rust agent B, the anti-rust agent A comprises N-[3-(dimethylamino) propyl]-N, N-dimethylformamide, and the anti-rust agent B comprises N-[3-(dimethylamino) propyl]-N, N-dimethylformamide. The antirust agent A comprises at least one of N, N ', N'-trimethyl-1, 3-propanediamine, benzotriazole, sebacic acid and 2, 4, 6-tri (aminocaproic acid)-1, 3, 5-triazine, and the antirust agent B comprises at least one of an imidazoline compound and fatty acid sarcosine ester. The cutting fluid provided by the invention has excellent corrosion resistance, rust resistance, defoaming property, biodegradability and storage stability, and has a good application prospect.

The invention discloses a high-thermal-conductivity PI / ceramic composite insulation packaging sheet and a preparation method thereof, and relates to the technical field of electronic packaging. The high-thermal-conductivity PI / ceramic composite insulation packaging sheet is obtained by mixing a modified polyimide solution and modified ceramic particles according to the mass ratio of (9-13): 1 and then performing high-temperature curing. The modified polyimide solution is obtained by mixing a dianhydride monomer and a diamine monomer in a molar ratio of 1: 1, and 2-methyl-2-acrylic acid-2, 3-dihydroxy propyl ester accounting for 5-10% of the total molar weight, and adding a catalyst for catalysis; the modified ceramic particles are obtained by adding hydroxymethyl acrylamide into a ceramic suspension, mixing, filtering, washing and drying. The packaging sheet prepared by the invention has high thermal conductivity, keeps stable at a relatively high temperature, is not easy to thermally deform, and has relatively high stability.

The invention discloses a reaction buffer solution for improving endotoxin detection sensitivity of a recombinant tachypleus amebocyte lysate, a kit containing the reaction buffer solution and application of the reaction buffer solution. The reaction buffer solution comprises the following components: a Tris-HCl buffer solution, magnesium ions, sodium chloride, cane sugar, ethylene glycol diethyl ether diamine tetraacetic acid, a nonionic surfactant and cyclodextrin or a derivative thereof. The invention also discloses a preparation method of the reaction buffer solution and a kit containing the reaction buffer solution. When the reaction buffer solution or the kit is used for detecting the endotoxin of the recombinant tachypleus amebocyte lysate, the sensitivity of the recombinant tachypleus amebocyte lysate for detecting the endotoxin can be improved by one order of magnitude, the lowest detection limit can reach 0.0005 EU / ml, the reaction buffer solution or the kit has strong anti-interference capability and short reaction time, and the detection efficiency is greatly improved.

The invention discloses a recombinant C factor protein protective agent and application thereof. The recombinant factor C protein protective agent is prepared from the following components according to the final concentration of each component: 0.05 to 0.2 percent (w / v) of ProClin 300, 100 to 300 mM of sodium chloride, 1 to 10 mg / mL of bovine serum albumin, 5 to 20 percent (w / v) of trehalose, 10 to 50 percent (v / v) of glycerol, 0.1 to 0.5 percent (w / v) of tween-20 and 0.1 to 1 mM of ethylene glycol diethyl ether diamine tetraacetic acid with the pH value of 8.0. The invention also discloses an application of the recombinant factor C protein protective agent in refrigerated preservation of recombinant factor C protein. After the recombinant C-factor protein protective agent and the recombinant C-factor protein are mixed, the recombinant C-factor protein is prevented from being influenced by conditions such as aggregation, oxidation, freeze thawing and metal ion dependent inactivation, the stability of the recombinant C-factor protein in refrigeration storage is improved, and the activity retention rate of the recombinant C-factor protein after refrigeration storage for 12 months is greater than or equal to 90%; and the accuracy and sensitivity of endotoxin detection are maintained.

The invention discloses an anti-ultraviolet spinning yarn and a preparation method thereof, and relates to the technical field of spinning yarns. When the anti-ultraviolet spinning yarn is prepared, 2, 4, 6-tri (4-hydroxyphenyl) boroxane and methylphenyl phosphonium chloride are subjected to a reaction, and a phosphorus-boron composite flame retardant is prepared; the preparation method comprises the following steps: polymerizing indole and 5-(aminomethyl) indole to coat the surface of nano titanium dioxide to prepare pre-modified nano titanium dioxide; the pre-modified nano titanium dioxide and (3-acryloyloxypropyl) tri (trimethylsiloxy) silane are subjected to a reaction, and modified nano titanium dioxide is prepared; mixing poly (pentamethylene diamine adipate), the modified nano titanium dioxide and the phosphorus-boron composite flame retardant, and performing melt spinning to obtain polyamide fibers; spinning polyamide fibers to obtain polyamide spun yarns; the polyamide spinning yarn is sequentially finished with the chloroacetic acid finishing liquid and the isoliquiritigenin finishing liquid, and the anti-ultraviolet spinning yarn is prepared. The anti-ultraviolet spinning yarn prepared by the invention has excellent anti-ultraviolet, flame-retardant and anti-static properties.

The present invention relates to a hetero (aromatic) ring-substituted cyclic diamine compound, the preparation thereof and the use thereof in the preparation of a drug for treating and / or preventing tumors. The structural formula of the compound is as shown in (I). The compound has a significant inhibitory effect on the growth of cells of tumors such as leukemia, lymphoma, breast cancer, melanoma, ovarian cancer, colorectal cancer, cervical cancer, lung cancer, prostate cancer, esophageal cancer, glioma, kidney cancer, nasopharyngeal carcinoma, liver cancer, gastric cancer and pancreatic cancer. Compared with the prior art, the compound of the present invention has a broad-spectrum anti-tumor activity, has a good effect on inhibiting tumors, and has an effect of degrading PD-L1 proteins, and is thus a PD-L1 immunomodulator.

The invention provides an antistatic agent for fuel oil and a preparation method thereof, and belongs to the technical field of petrochemical engineering, and the preparation method comprises the following steps: S1, adding soybean lecithin and chlorosulfonic acid into dichloroethane, uniformly mixing, under the protection of nitrogen, heating and stirring for reaction, neutralizing reaction liquid, and performing rotary evaporation to obtain sulfonated soybean lecithin; the preparation method comprises the following steps: adding sulfonated soybean lecithin and ethidene diamine into absolute ethyl alcohol, then adding p-toluenesulfonic acid, heating and stirring for reaction, and carrying out reduced pressure distillation to obtain modified soybean lecithin; s2, dispersing the SiO2 particles in absolute ethyl alcohol, adding KH-550, and performing ultrasonic treatment, centrifugation and drying to obtain pretreated SiO2 particles; and uniformly mixing the modified soybean lecithin and the pretreated SiO2 particles, adding the mixture into a supercritical fluid reactor, heating and pressurizing, ultrasonically dispersing, and drying to obtain the antistatic agent. The antistatic agent has the advantages of good dispersibility, strong stability and strong antistatic capability.

The invention relates to the technical field of flocking fibers, and discloses a fiber material for electrostatic flocking of an automobile spring and a preparation method thereof.The preparation method comprises the steps that a diamine monomer and a diacyl chloride monomer are subjected to a polymerization reaction and then react with KH550 modified mesoporous nano-silica, and polyamide modified mesoporous nano-silica is obtained; and finally, blending with nylon 66, melting and spinning to obtain the nylon fiber. The silicon dioxide contains a hollow mesoporous structure, and when sound waves enter the silicon dioxide, the sound waves can be reflected and scattered for multiple times in the internal hollow and pore channels, so that the energy of the sound waves is dissipated, and a good sound absorption effect is achieved. Meanwhile, a polyamide molecular chain grafted on the surface of the silicon dioxide contains a large number of hydrophobic alkyl long chains which are uniformly dispersed in a fiber matrix, so that the hydrophobicity of the fiber matrix can be improved, the water contact angle and the water resistance and waterproofness are improved, and good practical application is achieved in the aspects of electrostatic flocking fibers for automobile springs and the like.

The invention discloses a high-bonding-strength conductive adhesive and a preparation method and application thereof.The preparation method comprises the following steps that S1, epoxy resin E51 is placed in a three-neck flask, acetone is added, stirring is conducted till the epoxy resin E51 is completely dissolved, and ethidene diamine is slowly dropwise added; s2, under the protection of nitrogen, heating to 70-80 DEG C, adding a catalyst triphenylphosphine, carrying out a constant-temperature reaction, after the reaction is completed, cooling to 35-45 DEG C, adding deionized water, and stirring; s3, acetone and unreacted ethylenediamine are removed, then deionized water is used for washing, an obtained product is placed in a vacuum drying oven to be dried, and amino modified epoxy resin of faint yellow viscous liquid is obtained; s4, mixing the amino modified epoxy resin with an anhydride curing agent, a conductive filler, a diluent and a coupling agent; and S5, fully stirring the mixture, carrying out vacuum defoaming, and uniformly stirring to obtain the conductive adhesive. According to the invention, the shearing strength of the chip and the copper bracket can be improved to more than 30MPa.

The invention discloses a bio-based fiber reinforced composite material and a preparation method thereof, and belongs to the technical field of bio-based fiber composite materials. The bio-based fiber reinforced composite material is prepared from the following raw materials in parts by weight: 60 to 80 parts of nylon 6, 10 to 20 parts of bio-based aramid fiber, 5 to 10 parts of modified carbon fiber, 2 to 6 parts of hyperbranched polyester modified zinc oxide and 1 to 3 parts of antioxidant, the bio-based aramid fiber is prepared by reacting 2, 5-furandicarbonyl chloride with two diamine monomers, and the two diamine monomers respectively contain trifluoromethyl and sulfuryl; the modified carbon fiber is obtained by grafting polyamidoamine on the surface of carbon fiber; the hyperbranched polyester terminal group of the hyperbranched polyester modified zinc oxide contains an epoxy group. The modified carbon fiber, the bio-based aramid fiber and the hyperbranched polyester modified zinc oxide are added into the nylon matrix, so that the composite material is endowed with good ultraviolet resistance, comprehensive mechanical properties and durability.