623 results about "Tetramethylethylenediamine" patented technology

The invention discloses a preparation method for sodium alginate-acrylamide-based hydrogel. The preparation method comprises the following steps of: dissolving sodium alginate powder in deionized water; then sequentially adding an acrylamide monomer, a methylene diacrylamide cross-linking agent, ammonium persulfate and an N,N,N',N'-tetramethylethylenediamine catalyst; uniformly stirring the materials, pouring the mixture into a glass die, and heating the mixture to obtain a hydrogel; completely soaking the hydrogel in a 0.01-1 mol/L non-monovalent cation aqueous solution for 1-10 hours, wherein cations diffuse and enter in a hydrogel network structure, and induce sodium alginate to cross-link, so as to generate the high-strength and high-toughness sodium alginate-acrylamide-based hydrogel during the process. The hydrogel disclosed by the invention has the following performances: the highest tensile strength can achieve 1 MPa, and the highest tensile elasticity modulus can achieve 250 KPa; a loading-unloading test is performed on the hydrogel, and when the great tensile multiple before unloading is 8, the highest dissipated energy can achieve 2180 KJ/m<3>.

The invention discloses postoperation anti-adhesion hydrogel and a preparing method thereof. The hydrogel is prepared from sodium alginate powder, chitosan powder, acrylamide monomers, N,N'-methylene bisacrylamide, calcium sulfate, ammonium persulfate and N,N,N',N'-tetramethylethylenediamine. The preparing method of the high-strength high-tenacity chitosan and sodium alginate compound hydrogel is easy to operate, parameters are controllable, the materials are easy to obtain, and the solvent is nontoxic or low in toxicity and safe to treat and use; the method integrates advantages of the two natural biological materials, and the requirement for postoperation adhesion prevention of patients and the requirement for nursing care and treatment of medical workers can be met well. The hydrogel is soft, can be attached to the skin easily, has good flexibility and can effectively prevent wound surface adhesion and be degraded and absorbed, secondary trauma is avoided, and the hydrogel is expected to become a novel postoperation anti-adhesion material.

The invention relates to a preparation method of biocompatible photo-thermal response self-healing conductive hydrogel, which includes: preparing solution from N,N-dimethyl acrylamide monomer, potassium persulfate serving as initiator and N,N,N',N'-tetramethylethylenediamine serving as accelerator; then soaking graphene hydrogel into the monomer solution for solution displacement and standing; and finally, initiating polymerization reaction at the room temperature, so that the biocompatible photo-thermal response self-healing conductive hydrogel is prepared. The preparation method is simple in process, mild in reaction condition, short in reaction time and suitable for industrial production. The hydrogel uses the graphene as a three-dimensional network framework, the graphene is high in reduction degree, chemical stability, electric conductivity and mechanical strength and good in photothermal conversion effect, and the hydrogel shows good self-healing performance within the body temperature range and under near-infrared irradiation.

The invention relates to a preparation method of hydrophobically associating polymer inverse emulsion and belongs to the technical field of water-soluble polymer synthesis. The preparation method comprises the following steps: changing the dissolution or interfacial property of a hydrophobic monomer by virtue of inclusion interaction cyclodextrin, and on this basis, copolymerizing the hydrophobic monomer with water-soluble monomers of acrylamide, sodium acrylate, 2-acrylamido-2-sodium methylallyl sulfonate and the like in inverse emulsion to obtain a hydrophobically associating polymer inverse emulsion product by taking potassium persulphate-tetramethylethylenediamine as a redox initiator system. The preparation method is cheap and easily-available in raw material and simple in process and after treatment; and meanwhile, the product is good in water-solubility, can be dissolved quickly, and has significant thickening property, shearing resistance and temperature and salt resistance, so that the product has an extensive application prospect in the fields of oil field, daily chemical, water treatment and the like.

The invention discloses an amphoteric ionic Gemini surfactant shown in a structural general formula (I), which is characterized in that R is alkyl of CnH2n +1, and n is equal to the integer of 418. The surfactant takes fatty acid as a raw material, and the fatty acid is reduced to obtain alpha-bromo fatty alcohol through alpha-bromo; and the alpha-bromo fatty alcoho is reacted with propane sultone to obtain alpha-bromo alkoxy propane sulfate, and finally, the alpha-bromo alkoxy propane sulfate is reacted with tetramethylethylenediamine to obtain the amphoteric ionic Gemini surfactant. The surfactant has higher surface activity, excellent synergetic property, excellent soft smoothness and antistatic property for fabrics, good wetting and foaming properties, and good absorption property for the surface of the charged material, and does not produce a water-repellent thin layer.

The invention discloses an intelligent hydrogel as well as a preparation method and an application thereof and a hydrogel. The intelligent hydrogel is P(NIPAM-co-CS)/Fe3O4 and comprises iron oxide, N-isopropyl acrylamide and chitosan. The preparation method comprises the following steps: dissolving FeCl2.4H2O and FeCl3.6H2O in a mixed solvent of ethanol and water and reacting to prepare hydrophilic Fe3O4 nanoparticles under the protection of nitrogen and by adopting ammonia water as a precipitating agent; ultrasonically dispersing the prepared Fe3O4 nanoparticles in a chitosan liquid, adding a temperature-sensitive monomer N-isopropyl acrylamide and in the presence of a crosslinking agent and an initiator and by adopting tetramethylethylenediamine as an accelerator, carrying out polymerization reaction to prepare the intelligent hydrogel P(NIPAM-co-CS)/Fe3O4 by virtue of a micro-emulsion polymerization method. The intelligent hydrogel can be applied in the preparation of a water body heavy metal ion adsorption-desorption agent for removing heavy metal ions in water body.

The invention provides N,N,N,N-tetramethylethylenediamine sulphonate ionic liquid and a preparation method thereof, belonging to the technical field of organic chemical synthesis. The preparation method of the ionic liquid comprises the following steps: using N,N,N,N-tetramethylethylenediamine and sultone to react at room temperature in the presence of acetone and absolute ethanol to obtain N,N,N,N-tetramethylethylenediamine sulphonate inner salt, and then using N,N,N,N-tetramethylethylenediamine sulphonate inner salt to react with inorganic acid or organic acid to obtain disulfonic acid groupacidic ionic liquid with N,N,N,N-tetramethylethylenediamine cationic group. The prepared ionic liquid can be used as the catalyst or solvent of organic reactions, in particular to the catalytic reaction of inorganic acid or organic acid; compared with the existing monosulfonic group acidic ionic liquid used as catalyst, the N,N,N,N-tetramethylethylenediamine sulphonate ionic liquid has higher catalytic activity, less dosage, less loss in cycle use, higher product yield and more environmentally friendly.

The invention discloses a polyoxyethylene alkylphenol ether (n) ester cationic gemini surfactant using glycine ester group as linker and a preparation method thereof. The preparation method comprises the following steps: adding solvent, polyoxyethylene alkylphenol ether (n) chloroacetate and tetramethylethylenediamine in a reactor, stirring, heating and refluxing to react for serveral hours and obtain the surfactant solution; and further removing reaction solvent, purifying with mixed solvent, performing vacuum drying to obtain the polyoxyethylene alkylphenol ether (n) ester cationic gemini surfactant which uses glycine ester group as linker and has higher purity. The surfactant of the invention has higher surface activity and better emulsifying ability. The preparation method is simple, the conditions are easy to control, the product is easy to separate and the sources of raw materials are rich.

The invention discloses a hydrogenated rosin-based quaternary ammonium salt gemini surfactant. The surfactant has the following structural formula, wherein in the formula, R has a tricyclic phenanthrene structure of dihydroabietic acid or tetrahydroabietic acid of hydrogenated rosin. The invention also discloses a preparation method for the hydrogenated rosin-based quaternary ammonium salt gemini surfactant. The preparation method comprises the following steps of: performing esterification reaction on the hydrogenated rosin and epoxy chloropropane under microwave radiation to synthesize a 3-hydrogenated rosin acyloxy-2-hydroxypropyl chloride intermediate, performing quaternization reaction on the 3-hydrogenated rosin acyloxy-2-hydroxypropyl chloride intermediate and tetramethyl ethylenediamine, and thus obtaining the hydrogenated rosin-based quaternary ammonium salt gemini surfactant. Compared with the conventional heating synthetic method, the method using microwave radiation heating has the advantages that the reaction time can be greatly shortened and the preparation process is simple.

The invention relates to a preparation method of a self-healing hydrogel and belongs to the technical field of biomedical high-molecular materials. The preparation method comprises adding dopamine into an alkaline solution so that dopamine self-polymerizes to form a dopamine prepolymer; adding N,N'-methylene bisacrylamide, ammonium persulfate, acrylic acid and N,N,N',N'-tetramethylethylenediamineso that the hydrogel is formed through polymerization of their free radicals. Compared with the prior art, the self-healing hydrogel prepared herein has the advantages that operation is simple, conditions are easy to control, the self-healing hydrogel is available for industrial production, the reaction conditions are mild, and the cost is low. Hydrogels with different adhesive features and tensile properties can be prepared according to actual needs.

The invention relates to the porous ceramics material field, and concretely relates to a method for manufacturing high porosity and high strength yttrium-silicon-oxygen porous ceramics material through a foaming injection coagution process. According to the method, yttrium oxide and silicon oxide mixed power can be taken as a raw material, water is taken as a disperse medium, polyethyleneimine or ammonium citrate is selected as a dispersant, acrylamide or N-methylolacrylamide is taken as a monomer, a cross-linking agent N,N'-methylene bisacrylamide is added, a foaming agent sodium dodecyl sulfate, a peeling inhibitor polyoxyethylene, a catalyst N, N, N',N'-tetramethyl ethylenediamine and an initiator ammonium persulfate are added after stirring, and then injection mold solidification is carried out, drying is carried out for 24-48 hours at room temperature after demoulding, and then drying is carried out for 24-36 hours under the temperature of 60-90 DEG C, high temperature reaction sintering is carried out for 1.5-2.5 hours under the temperature of 1500-1550 DEG C finally, and the gamma-Y2Si2O7 porous ceramics can be finally manufactured. The manufactured gamma-Y2Si2O7 porous ceramics material having a multi-layer pore structure has controllable porosity with high porosity (75-85%) and high strength (3-8MPa).

The invention discloses polyethylene glycol-chitosan self-assembled nanoparticles and a preparation method thereof, belonging to the technical field of preparation of a functional material. Chitosan derivative with water solubility and biocompatibility is obtained by modifying chitosan by polyethylene glycol, so as to prepare the polyethylene glycol-chitosan self-assembled nanoparticles. The polyethylene glycol-chitosan self-assembled nanoparticles have the advantages that TEMED (tetramethylethylenediamine).HCL is taken as a diluent; EDC (dichloroethane) and NHS are taken as activating agents under a mild condition; the polyethylene glycol chitosan derivative with water solubility and biocompatibility is prepared by grafting mPEG-COOH on CS in a covalent coupling manner and modifying the chitosan by PEG (polyethylene glycol), so that the nanoparticles can be formed in a water solution in a self-assembling manner.

A Chitosan-arginine conjugate as anticoagulant material is prepared through dissolving chitosan in the solution of N, N, N'-tetramethyl ethanediamine, adding 1-ethyl-3-(3-dimethylamino propyl) carbodiimine, N-hydroxy-butanediimide and arginine, reacting while magnetic stirring, dialyzing, drying to obtain said conjugate, adding glucosyl aldehyde oxide, and cross-linking reaction to become film. Its advantages are high effect and low poison to cell.

The invention provides a preparation method of controllable and visual chlorine dioxide slow-release gel, and relates to the technical field of gas sterilization and deodorization. The method comprises the steps of respectively dissolving water-soluble materials including sodium chlorite, acrylamide, bisacrylamide, borax, potassium persulfate and the like, mixing in proportion, carrying out split charging, then feeding tetramethylethylenediamine, and carrying out polymerization reaction to obtain the polyacrylamide gel. When the controllable and visual chlorine dioxide slow-release gel is used, a matched acidification rod is inserted into the gel, and chlorine dioxide gas can be slowly released, so that the effects of sterilization and deodorization for the surrounding environment can be achieved. The method has the characteristics that the slow-generation and slow-release speed of the chlorine dioxide can be controlled by controlling the concentrations of the gel and the borax, the degree of crosslinking of the gel and the type of the acidification rod; the gel at the rear end of the product is formed by polymerization and is colorless and transparent, thus being suitable for various shapes; after the product is acidized and activated, the gel becomes yellow from colorless, the chroma of the gel is in direct proportion to the concentration of the chlorine dioxide, and vice versa, so that the gel also has the function of ClO2 indicator; after the product is acidized and activated, the released gas does not contain toxic by-product chlorine.

The invention discloses a chitosan polyacrylamide hydrogel base material and a preparation method thereof. The chitosan polyacrylamide hydrogel base material is composed of an acrylamide solution, a methylene diacrylamide solution, H2O, an ammonium persulfate solution, tetramethyl ethylenediamine and a chitosan solution. The preparation method of the chitosan polyacrylamide hydrogel base material comprises a step of mixing and stirring, a step of transferring to a glass clamping plate for reacting, and a step of immersion. The chitosan polyacrylamide hydrogel base material has a simple technology and allows hydrogels having different hardnesses to be obtained, and the obtained hydrogels have the advantages of non-toxicity, easy adherence growth of cells, reduction of the reaching complexity of the cytomechanics, benefiting for the researches on the mechanical properties of the cells, and reduction of the researching cost.

The invention discloses a method for preparing a poly-N-vinylpyrrolidone-polyethylene glycol-poly-lactic acid copolymer shell layer cross-linked micelle. The process of the method comprises the following steps: polyethylene glycol monomethacrylate is firstly synthesized, and then the polyethylene glycol monomethacrylate-poly-lactic acid block copolymer which is provided with double bonds at the tail end of a PEG chain segment is prepared by the polymerization with lactide. Polyethylene glycol monomethacrylate-poly-lactic acid block copolymer micelle aqueous dispersion is prepared by the spontaneous emulsion-solvent method, then N-vinyl pyrrolidone is added in the presence of ammonium persulfate and tetramethylethylenediamine, thus obtaining the poly-N-vinylpyrrolidone-polyethylene glycol-poly-lactic acid copolymer shell layer cross-linked micelle. The method has the advantages that, the preparation process is simple; the prepared poly-N-vinylpyrrolidone-polyethylene glycol-poly-lactic acid copolymer shell layer cross-linked micelle has good stability and can be used as a drug release carrier with great drug loading and adjustable release rate.

The invention discloses a method for preparing porous ceramics in the technical field of inorganic nonmetallic materials. The porous ceramics are prepared by taking the hollow ceramic ball as a pore forming agent and using a gel casting process. The method comprises the steps: firstly, presintering the hollow ceramic ball; then, preparing low-viscosity ceramic slurry and degassing; placing the presintered hollow ceramic ball into the prepared ceramic slurry; uniformly stirring the slurry and degassing again; then, adding tetramethylethylenediamine and an aqueous solution of ammonium persulfate; carrying out injection molding after uniformly stirring the mixture; next, placing a slurry injected mold into a drying oven to heat; demolding after the slurry is completely cured, and carrying out drying, glue ejection, sintering and other processes to finally prepare the novel porous ceramics. The porous ceramics prepared by the invention are favorable in mechanical property, controllable in pore diameter distribution and uniform in air hole distribution; in addition, the adverse effects of the traditional pore forming agent on a blank body during burning can be avoided, the shrinkage and deformation of various prepared porous ceramics can be effectively inhibited, and the comprehensive performances of the prepared porous ceramics can also be effectively controlled.

The invention discloses a galactosylated chitosan scaffold material for a bioartificial liver, which is a galactosylated chitosan biological material with a three-dimensional porous structure which is cross-linked by an oxidized sodium alginate biological crosslinking agent. Its main preparation process: chitosan and lactobionic acid are dissolved in tetramethylethylenediamine/hydrochloric acid mixed solution in an equimolar ratio, and active intermediates are added to activate the reaction to prepare galactosylated chitosan; galactosylated chitosan is dissolved in Acetic acid solution and oxidized sodium alginate are dissolved in ultrapure water, and the two solutions are mixed in a certain proportion to carry out cross-linking reaction. After the reaction is completed, pour it into a mold for molding, freeze-dry to obtain a scaffold material, and then immerse it in sodium hydroxide- The residual acetic acid was removed by ethanol aqueous solution, and then washed by ethanol aqueous solution and freeze-dried twice to obtain the galactosylated chitosan scaffold material cross-linked by oxidized sodium alginate. The galactosylated chitosan scaffold material of the invention has a pore size suitable for the growth of liver cells and good biocompatibility.

The invention discloses a method for preparing a nuclear fuel, which comprises the following steps: mixing acrylic amide, subunit bisacrylamide, ammonium polyacrylate and deionized water to form premix solution; adding U3O8 powder into a ball mill, then adding the premix solution into the ball mill, and preparing U3O8 slurry of which the solid-phase content is more than or equal to 60vol percent and the viscosity is less than or equal to 1Pa.s through ball-milling dispersion; adding ammonium sulfate and tetramethyl ethylene diamine into the slurry, evenly mixing the slurry and then injecting the slurry into a die, solidifying the slurry, and removing the die to obtain an annular U3O8 raw blank; drying the raw blank at the temperature of between 60 and 80 DEG C and the humidity of between 80 and 95 percent, and un-sticking the raw blank at the temperature of 600 +/- 20 DEG C; and sintering the un-stuck annular U3O8 raw blank in the hydrogen atmosphere at the temperature of 1,730 +/- 10 DEG C to obtain an annular UO2 fuel pellet. The method has the advantages that the relative density of the primary pellet blank reaches 60%-70%, the breaking strength is over 20MPa, and the size-grinding machining allowance of a sintered body is minimized through mechanical machining and precise size control.

Drug-loading thermosensitive hydrogel. Raw materials for preparation of the drug-loading thermosensitive hydrogel contain N-isopropylacrylamide, acrylamide and hydroxyethyl cellulose. Corresponding steps contain: dissolving hydroxyethyl cellulose in distilled water; adding an intermixture of N-isopropylacrylamide and acrylamide into a hydroxyethyl cellulose solution; adding an initiator potassium peroxodisulfate and an additive tetramethylethylenediamine, and introducing nitrogen for protection so as to obtain a grafting product; drying the grafting product, and extracting in an extractor by using acetone as an extractant; dissolving the purified grafting product in distilled water, adding sodium hydroxide and a cross-linking agent epoxy chloropropane, and carrying out magnetic stirring to obtain a drug-loading thermosensitive hydrogel semi-finished product; and soaking the semi-finished product in deionized water to obtain the drug-loading thermosensitive hydrogel with lower critical solution temperature being 37-41 DEG C. the product has equal level of mechanical strength in comparison with the prior art. In addition, the preparation is more convenient to operate, and time cost is saved.

The invention discloses a method for adsorbing heavy metal ions by corncob cellulose-based hydrogel. The method comprises the steps of dissolving corncob cellulose at first, adding montmorillonoid toheat and stir to insert the corncob cellulose into montmorillonoid layers, adding tetramethyl ethylenediamine and ammonium persulfate to stir, then adding acrylic acid and N,N'-methylene bisacrylamideand continuing heating and stirring to obtain the hydrogel. The corncob cellulose is pure cellulose which is extracted from corncob by a nitric acid-ethyl alcohol method. By means of optimizing dosage of the montmorillonoid, the N,N'-methylene bisacrylamide and the acrylic acid, the corncob cellulose-based hydrogel which has the optimal structure and adsorption performance is obtained; by means of optimizing different concentrations, pH values and adsorption times of the heavy metal ion solutions, the optimal adsorption condition of the hydrogel disclosed by the invention is determined. The preparation method disclosed by the invention has the advantage of simple technology, and the prepared hydrogel has the advantages of better adsorption performance, better structural stability and goodadsorption effect on heavy metal ions.

The invention relates to a preparation method capable of improving the composition obtained by recycling hydrocarbon, and belongs to the field of preparation of a quaternary ammonium compound. The preparation method comprises the following steps of mixing alpha-alkyl halide and N, N, N', N'-tetramethylethylenediamine at the mole ratio of (2-3):1, and stirring at 50-90 DEG C for 8-16 hours, thereby obtaining the quaternary ammonium salt type dimeric surfactant. A purification method comprises the following steps of recrystallizing a crude product of the quaternary ammonium salt type dimeric surfactant obtained by the preparation method by using a solvent, then drying so as to obtain a white powdery solid which is the purified quaternary ammonium salt type dimeric surfactant. According to the preparation and purification methods of the quaternary ammonium salt type dimeric surfactant, a method of cooking in one pot is adopted, so that the inconvenience caused by charging step by step is prevented. Other reaction solvents are not added in the synthesis process, so that the production cost is reduced greatly, and the technological process is shortened; the synthesized surfactant is very high in productivity, is good in performance, and can be used for producing detergents, foam drilling fluids and displacement agent for tertiary oil recovery and the like.

The invention discloses a corneal contact lens drug carrier with bionic characteristics. The carrier is formed by carrying out polymerization on a cyclodextrin derivative containing double bonds, phosphorylcholine, hydroxyethyl methacrylate and an initiator, wherein the average functionality of the double bonds in the cyclodextrin derivative containing the double bonds is 1.1-1.5; the mass of phosphorylcholine is 0.1-1% of the total mass of the cyclodextrin derivative containing the double bonds and hydroxyethyl methacrylate; the mass ratio of hydroxyethyl methacrylate to the cyclodextrin derivative containing the double bonds is (1-20): 1; the initiator comprises ammonia sulfate and tetramethyl ethylenediamine. The invention provides the novel corneal contact lens drug carrier with good oxygen permeation performance and drug controlled release capability; the obtained product is in accordance with the basic requirements of a corneal contact lens and is capable of controlling the release of eye ointment. The corneal contact lens drug carrier with bionic characteristics has higher social benefit and economic benefit.