80 results about "Tissue deformation" patented technology

The invention is directed to nanostructure surface treatments, coatings or modifications formed from nanoscale building blocks. The nanostructure surface treatments, modifications or coatings have hydrophobic, hydrophilic and surface adherence properties. The nanoscale building blocks have orientation, geometry, packing density and composition that may be adjusted to control the unique surface characteristics of the desired treatment, coating or modification. Applications of this nanostructure technology include surgical clips, staples, retractors, sutures and manipulators where an improvement in traction, retention or occlusion is desired without excessive material or tissue deformation or where high compressive forces would be undesirable, dangerous or ineffective. In one aspect, a nanostructure surface treatment for a medical device having an external surface is disclosed, wherein the treatment is applied on the external surface to provide a hydrophobic or a hydrophilic surface. With this aspect, the treatment comprises titanium dioxide and provides nanoscopic structures having nearly vertical sidewalls. The treated surface of the device has contact angles greater than or equal to 150 degrees. The vertical sidewalls provide a negative capillary effect and have a width of about 200 nm. The vertical sidewalls attach to a wet surface by the negative capillary effect. The van der Waals forces of the vertical sidewalls enable the treated surface to attach to a dry surface. The treatment may be vapor deposited and cured on the device, or the treatment may be laser blasted on the device.

Methods and devices are provided for delivering a drug to or withdrawing a fluid from a biological tissue, such the skin, sclera, cornea, and conjunctiva. One method includes the steps of inserting at least one microneedle into the biological tissue; partially retracting the at least one microneedle from the tissue; and then delivering at least one drug formulation into the biological tissue via the partially retracted at least one microneedle. The microneedle deforms and penetrates the biological tissue during the insertion step, and the retraction step at least partially relaxes the tissue deformation while maintaining at least part of the tissue penetration, facilitating drug delivery or fluid withdrawal.

A system and method is provided for an injectable substance delivery device comprising a limiter, shoulder or post, that controls how deep the needle is inserted into the tissue. The limiter is sized in proportions that control the maximum insertion depth of the needle into the tissue without excessively restricting the complete insertion of the needle. The system and method further comprises an normalization or stabilizer ring that prevents distortion of the tissue in the vicinity of the infusion, so that the needle length is the major determining factor as to how deep the infusion is delivered.

The invention provides an intraoperative tissue tracking method combined with a preoperative image, which comprises the following sequential steps: the first step: preoperative preparation, including the steps of acquiring a space position of a marking point in the preoperative image and calibration of equipment; and the second step: deformation tracking of an intraoperative tissue, including 1, coordinate system registration which is one of main parts of the invention; and 2. tissue deformation and fusion display which is also one of the main parts of the invention. By using intraoperative real-time two-dimensional ultrasound image and endoscope image and intraoperative electromagnetic or optical positioning system and using algorithm analysis and geometric registration calculation, a tissue structure of an intraoperative interest tissue can be reflected in the image.

The invention relates to a robot-assisted oblique-tip flexible needle puncture system and method. The method comprises the following steps: obtaining the position of a puncture platform and a puncture path through preoperative planning; moving a positioning mechanism to a specified position and locking the positioning mechanism, and controlling a puncture mechanism to enable a flexible needle to reach a penetration point of puncture; puncturing according to the planned puncture path; optimizing, by a path planning module, the puncture path of the flexible needle on line in real time according to flexible needle tip position information, attitude information and a puncture region tissue image fed back by a three-dimensional electromagnetic positioning sensor and a C-shaped arm in the puncture process; correcting the flexible needle by a controller according to a real-time on-line optimization strategy of the path planning module; ending the puncture process after the puncture needle reaches a target position. According to the method and the device, the position of the needle tip can be obtained in real time, the stress of the needle tip is obtained in real time, the puncture strategy is corrected on line according to tissue deformation to guarantee that the oblique-tip flexible needle can bypass an unpuncturable region to accurately reach a focus, and the puncture process is put under the monitoring of a doctor to guarantee the safety of the puncture surgery.

The invention relates to a high-strength aluminum alloy isothermal direction-change open die forging method which comprises the following steps: heating preprocessed high-strength aluminum alloy blank in a direction-change isothermal forging heating holding furnace at the temperature of 350-450 DEG C, and keeping the furnace temperature unchanged; and according to the structure property indices required by the blank, repeatedly upsetting and drawing the blank in the direction-change isothermal forging heating holding furnace until the blank reaches the design size of the forge piece. The isothermal direction-change open die forging device comprises a heating furnace and a forging press, wherein the furnace body is installed on the forging platform of the forging press; the forging rammer of the forging press is installed in a through hole in the furnace bottom plate; and the forging head of the forging press is installed in a through hole in the furnace top plate. The invention has the advantages of simple technique, convenient operation, and low tendency to recrystallization, enables the high-strength aluminum alloy to be under isothermal conditions all through the direction-change open die forging process, does not need to heat the blank again in the forging process, improves the quality of the forge piece and enhances the forging efficiency; and the forge piece has the advantages of sufficient structure deformation, uniform deformation at each part, and low tendency of cracking. The forge piece has favorable structure properties, and is suitable for industrial production.

Systems and methods of developing a tissue deformation profile for a foot of a patient. The tissue deformation profile can be used to identify a desired configuration for an orthotic device. A method uses a sensing orthotic device to assist in the treatment of foot issues. The orthotic device can have at least two sensors and at least one actuator for adjusting physical parameters of the orthotic device.

System and method for determining viscoelasticity of curved tissue walls using ultrasound bladder vibrometry (UBV). The UBV is a non-invasive technique utilizing, in a specific case, a focused ultrasound radiation force to excite Lamb waves in a curved bladder wall and pulse-echo techniques to track the tissue deformation propagating through such curved wall. Cross-spectral analysis is used to calculate the wave velocity, which is directly related to the elastic properties of the bladder wall.

A deep machine-learning approach is used for medical image fusion (24) by a medical imaging system (48). This one approach may be used for different applications. For a given application, the same deep learning is used but with different application-specific training data. The resulting deep-learnt classifier provides a reduced feature vector in response to input of intensities of one image and displacement vectors for patches of the one image relative to another image. The output feature vector is used to determine (16) the deformation for medical image fusion (24).

In an imaging procedure, sound pressure is generated by applying ultrasound to the region to be imaged in order to cause a deformation of tissue therein from at least one acquired ultrasound image data set, first data are determined that represent, with spatial resolution, the deformation of the tissue as a reaction to the sound pressure. At least one magnetic resonance image data set is acquired, from which second data are determined that represent, with spatial resolution, the deformation of the tissue as a reaction to the sound pressure. The at least one ultrasound image data set and the at least one magnetic resonance image data set are brought into registration with each other by a comparison of the first data and the second data.

The invention discloses a jellyfish paraffin section making method. The method comprises the steps of raw materials processing and fixing, dehydration, transparency realization, waxing, embedding, sectioning and dyeing. The method is suitable for the fixing, dehydration, transparency realization, waxing, embedding, sectioning and dyeing of different raw jellyfishes. A secondary fixing method combining a neutral buffering formaldehyde fixing liquid with an alcohol-acetic acid-formaldehyde mixed liquid, and the formula of a routine alcohol-acetic acid-formaldehyde mixed fixing liquid is adjusted, so the dehydration time is shortened, and the section production efficiency is improved; and the waxing time and temperature control conditions suitable for the jellyfish are established. The tissue deformation problem in the jellyfish paraffin section making process is overcome in the invention, and ideal paraffin tissue blocks and dyeing effect are realized. The making is suitable for making jellyfish paraffin sections with high content and rich in collagens, and the method provides a histomorphologic support for the monitoring of the quality of jellyfish in the processing process.

The invention discloses a virtual dental implant surgery training system. The system comprises a computer, a VR head-mounted display device and a force feedback device. The computer is provided with atissue deformation unit, a surgical tool unit, a force feedback unit and a collision detection unit. The tissue deformation unit renders a three-dimensional oral model on the VR head-mounted displaydevice. The VR head-mounted display device and the force feedback device are interacted with a student. The collision detecting unit is used to detect the movement information of the force feedback device and send to the tissue deformation unit for processing. The tissue deformation unit sends force feedback information to the force feedback device through the force feedback unit, and the force feedback device generates force feedback based on the force feedback information. The system provides a realistic and immersive training environment, the student can carry out dental implant operation on a virtual model, understand an oral structure, and be familiar with the whole process of a dental implant surgery, and problems during a dental implant surgery process, and a dental implant surgerytraining effect is increased.

Disclosed is a real-time soft tissue deformation amount measurement method which is applied to robot-assisted flexible needle penetration experiments on soft tissues. According to the method belonging to the technical field of medical instruments for minimally invasive surgery, a real-time soft tissue deformation amount measurement device and a real-time soft tissue deformation amount measurement algorithm are adopted. A six-axis force/torque sensor serves as a core component of the device. The device further comprises a rectangular tissue support plate, a round tissue tray, a rectangular bottom plate, a data collection card and a computer. The round tissue tray is connected with the top end of the sensor, and the rectangular bottom plate used for fixing the sensor is connected with the bottom surface of the sensor. The computer is provided with signal processing software. The measuring device is fixed at the bottom of a tissue container. The signal processing software includes a tissue squeezing force calculation algorithm and a tissue deformation amount calculation algorithm. By the two calculation algorithms, real-time reading and calling of tissue squeezing force and real-time recording and displaying of tissue deformation amount are achieved, and accordingly, real-time display of the tissue deformation amount in the needle penetration experiments on the soft tissues is achieved.