One aspect of the present disclosure provides a non-invasive
intracranial pressure detection device comprising an interferometric near-
infrared spectroscopy (iNIRS)
system, the iNIRS
system comprising a
light source configured to emit light, a sample delivery channel coupled to the
light source and arranged to be coupled to the subject's
scalp for directing light from the
light source towards the subject's
brain tissue, a reference channel coupled to the light source for receiving light from the light source, an emitting device comprising the reference channel, and a
light detection device configured to couple the subject's
scalp to the emitting device, the
light detection device comprising an interferometric
photodetector configured to receive (i) reference light from the reference channel and (ii) sample light from the subject's brain, the sample light including light emitted from the light source, the interferometric
photodetector being arranged to couple the sample light and the reference light to provide a combined optical
signal including one or more components of the beat frequency between the sample light and the reference light, the
light detection device comprising a control device configured to process data indicative of the combined optical
signal to determine an indication of the intracranial
blood pressure of the subject based on at least one characteristic of the pulsatile waveform of one or more identified pulses of
blood flow through the subject's brain.