13 results about "Pulsatile blood flow" patented technology

The invention relates to the technical field of medical instruments, and provides a self-adaptive double-cavity cannula for pulsatile blood flow, the self-adaptive double-cavity cannula comprises a cannula body and an elastic diaphragm, the elastic diaphragm is arranged in the cannula body along the axial direction of the cannula body, the elastic diaphragm divides the internal cavity of the cannula body into a drainage cavity and a backflow cavity, and the drainage cavity is communicated with the backflow cavity. The far-end drainage opening and the near-end drainage opening are both communicated with the drainage cavity, the backflow opening is communicated with the backflow cavity, and the elastic diaphragm elastically deforms under the action of pulsatile pressure difference between the drainage cavity and the backflow cavity so as to dynamically change the overflowing sectional area of the drainage cavity and the overflowing sectional area of the backflow cavity. Thus, the elastic diaphragm is elastically deformed under the combined action of the blood flow pressure in the drainage cavity and the blood flow pressure in the backflow cavity, the overflowing area of the drainage cavity and the overflowing area of the backflow cavity can be dynamically adjusted in a self-adaptive mode along with the blood flow pulsation period, pulsation type blood flow generated by the heart can be well adapted, and the blood extraction efficiency and the blood infusion efficiency are effectively improved.

The present application relates to a TAVR teaching model based on blood flow simulation and multi-modal image fusion and use method. The model comprises a simulated thoracic and abdominal cavity with a built-in heart wave beat simulation part that drives fluid to generate pulsatile blood flow, a simulated thoracic and abdominal body with pre-set vascular access, a bionic heart assembly with structures such as a ventricular cavity, a pathological valve module that can be detachably fitted to the aortic valve ring and contains a pressure sensor array and simulated calcification, a coronary circulation monitoring module that monitors the perfusion state of the coronary artery opening, a virtual fluoroscopy positioning module that generates real-time fluoroscopy images, and a central control console that electrically cooperates with each module. The scheme simulates the tactile sensation of calcification through the pathological valve module, the heart wave beat simulation part reproduces the physiological pressure difference with a closed loop blood flow, realizes image navigation training with non-radiation virtual fluoroscopy, integrates real-time simulation of complications with coronary monitoring and annulus pressure sensing, and solves the problems of existing models such as distorted hand feeling, inaccurate dynamics, dependence on radiation, and lack of complication training.

The present application relates to a kind of microvascular pulsatile blood flow multi-parameter synchronous regulation microfluidic platform and method, belong to microfluidic chip technical field, including: for simulating human microvessel microfluidic chip, microfluidic chip is opened with liquid inlet hole, detection hole and waste liquid hole;For simulating pulsatile blood flow blood flow control module, blood flow control module includes ball screw drive module, blood injection component and microelectromechanical control component, blood injection component outlet and microfluidic chip liquid inlet hole communication, microelectromechanical control component electrically connected and control ball screw drive module movement, ball screw drive module can drive blood injection component to set up the speed waveform of class heart pulsation Perfusion blood to microfluidic chip;For detecting the microfluidic chip in blood pressure microfluid pressure detection module, microfluid pressure detection module inlet and detection hole communication.The present application can realize the synchronous simulation regulation of blood flow velocity, pressure and blood flow pulsatile characteristics in microvessel.

The present disclosure describes, in part, arterial cannula systems for extracorporeal membrane oxygenation and cardiopulmonary bypass provides pulsatile blood flow and selective flow distribution. The cannula comprises a multi-lumen structure including a central lumen for blood flow, dedicated lumens for helium delivery, a distal orifice for body perfusion, and proximal orifices for limb perfusion. An inflatable cuff positioned between the distal and proximal orifices modulates blood flow through rapid inflation and deflation cycles achieved in milliseconds using helium gas. An external control console with microcontrollers and customized software automates the inflation-deflation cycles based on physiological inputs including ECG, arterial pressure, and tissue oxygenation. The system restores physiologically effective pulsatile flow, prevents limb ischemia, reduces thrombus formation risk, and can provide ECG-synchronized flow modulation to facilitate native cardiac ejection, potentially eliminating the need for separate left ventricular venting during mechanical circulatory support.

A circulatory assist device for facilitating pulsatile blood flow within a subject's blood vessel is disclosed. The circulatory assist device includes a rotary component, a pulsatory component, and one or more electromagnets. The rotary component includes a driveline and one or more impellers connected to the driveline and configured to rotate with the driveline. The pulsatory component includes one or more sections configured to change diameter in response to a magnetic field applied thereto. The one or more electromagnets are positioned within the driveline and are configured to produce the magnetic field

The application aims to provide a blood circulation assisting system capable of generating pulsating blood flow and guaranteeing body functions, comprising a first blood circulation supporting unit located in a heart chamber of a patient and a second blood circulation supporting unit located in a descending aorta of the patient, the first blood circulation supporting unit pumping blood in the heart chamber to the aorta, and the second blood circulation supporting unit generating pulsating blood flow by periodically contracting and expanding to squeeze blood, and partially blocking the blood vessel when expanding. When the second blood circulation supporting unit periodically expands to squeeze blood, it does not completely block the blood vessel, but leaves a part of the blood flow passage, so as to allow part of the blood to pass through, prevent the ascending aorta pressure from suddenly rising, and prevent the blood from flowing back to the left ventricle, and also prevent the second blood circulation supporting unit from moving, so as to guarantee the pulsating effect and prevent unnecessary damage to the inner wall of the blood vessel.

Disclosed herein are devices, systems, and methods for treating conditions using an implantable damping device in combination with a therapeutic agent (e.g., a drug). Methods for treating the effects of one or more conditions, such as neurological conditions, include providing an implantable damping device and at least one other therapy, such as a therapeutic agent, to treat a condition in a patient. The implantable damping device includes a flexible damping member and a moderating substance and may be placed alongside the blood vessel. The flexible damping member forms a generally tubular structure having an inner surface and an outer surface, the inner surface being formed by a sidewall having a partially deformable portion. A moderating substance is disposed within the partially deformable portion and moves longitudinally and / or radially within the partially deformable portion in response to pulsatile blood flow.

The new invention relates to a method and to a corresponding device by means of which a pulsatile blood circulation with a purely layered flow outside the body is generated. No additional shear load is generated through the device. For this purpose, a closed annular channel (12), which is completely filled with blood (2), is rotated in the main plane thereof. A pulsatile blood flow in the same direction is achieved in such a way that a constant rotation of the annular channel (12) is quickly stopped. A laminar flow of blood is generated relative to the channel, which again reaches stationary. By interrupting the annular channel (12) with a blocking device (30), the blood (2) remains stationary relative to the channel even when restarted. The blocking device (30) is only opened again after a constant rotation has been reached, and the process is then cyclically repeated. Combination of the annular channel (12) and the blocking device (30) into one part can achieve a significant reduction in the test structure. Thus, a plurality of samples with small blood volumes can be tested in parallel. The device works as a blood pump when the blood circulation is divided into a movable hose ring (6) with stationary, open hose ends (61) (62) and an external connection (63) thereto.

The application discloses a kind of pulsatile ventricular assist device's hemodynamic test system, and test system includes: left atrial cavity, left ventricular cavity, aortic cavity, venous cavity and pulsatile blood flow generator module.The two ends of aortic valve module are connected with left ventricular cavity and aortic cavity respectively;Ventricular assist device passes through aortic cavity, aortic valve module and left ventricular cavity in turn by the sealing tool of aortic cavity, and respectively makes blunt head be placed in left ventricular cavity and bidirectional valve be placed in aortic cavity;Pulsatile blood flow generator module is connected left ventricular cavity, and left ventricular cavity is filled with liquid, and by reciprocating movement of piston extruding left ventricular model, to simulate the flow rule of human blood.The test system of the application can be used to simulate the preload and afterload of pulsatile ventricular assist device, detect the hemodynamic performance of ventricular assist device after implanting in human body, help ventricular assist device structure optimization and controller design.

The application discloses a magnetic suspension pulse counterpulsation extracorporeal membrane oxygenation system and a control method thereof, and belongs to the technical field of medical equipment. The system comprises a magnetic suspension blood pump, an oxygenator, a blood pump controller, and an electrocardio and pulse signal acquisition and analysis unit, which continuously collects electrocardiogram data and arterial pressure waveform data of a patient in a predetermined window period to form original data packets with time stamps. The electrocardio and pulse signal acquisition and analysis unit is used for collecting electrocardio signals and / or arterial pressure waveform signals of the patient in real time. The application simulates the hemodynamic effect of in-vivo balloon counterpulsation through the rotation speed control of the extracorporeal magnetic suspension blood pump, realizes pulsatile perfusion synchronized with the heart cycle, solves the problem of increased afterload caused by non-pulsatile blood flow of a traditional extracorporeal membrane oxygenation system, and fundamentally eliminates the risks of hemolysis, platelet destruction, thrombosis and vascular injury caused by the in-vessel balloon.

The invention belongs to the technical field of electrical impedance imaging, and particularly relates to a self-reference pulmonary pulse blood flow impedance signal gating extraction method and system.The method comprises the steps that an electrical impedance signal is obtained, spectral analysis is conducted on the electrical impedance signal, and a peak frequency is obtained; performing clustering analysis on the peak frequency to obtain a respiratory frequency set and a heartbeat frequency set; determining a reference impedance signal based on the heartbeat frequency set; based on the reference impedance signal, obtaining a single-heart-cycle electrical impedance signal through cutting and superposition; based on the single-cardiac-cycle electrical impedance signals, pulsatile blood flow electrical impedance signals of the average cardiac cycle are determined, the maximum value moment of the pulsatile blood flow electrical impedance signals of the average cardiac cycle serves as a reference frame, the minimum value moment serves as an imaging frame, and a spatial distribution diagram of the average pulsatile blood flow is obtained. Through spectral analysis and clustering analysis, the method does not need to dissect prior information to help select channels which can be regarded as reference signals, and does not need to synchronously collect electrocardiosignals to identify the cardiac cycle.

The present disclosure describes, in part, arterial cannula systems for extracorporeal membrane oxygenation and cardiopulmonary bypass provides pulsatile blood flow and selective flow distribution. The cannula comprises a multi-lumen structure including a central lumen for blood flow, dedicated lumens for helium delivery, a distal orifice for body perfusion, and proximal orifices for limb perfusion. An inflatable cuff positioned between the distal and proximal orifices modulates blood flow through rapid inflation and deflation cycles achieved in milliseconds using helium gas. An external control console with microcontrollers and customized software automates the inflation-deflation cycles based on physiological inputs including ECG, arterial pressure, and tissue oxygenation. The system restores physiologically effective pulsatile flow, prevents limb ischemia, reduces thrombus formation risk, and can provide ECG-synchronized flow modulation to facilitate native cardiac ejection, potentially eliminating the need for separate left ventricular venting during mechanical circulatory support.

Described is an intravascular device including a stent graft and at least one annular band. The intravascular device is configured for insertion into a blood vessel and configured to expand to contact the wall of a blood vessel after insertion therein. The annular band is configured to change in diameter in response to an applied potential difference. A method of maintaining and accelerating pulsatile blood flow includes positioning an annular band within a blood vessel, and causing the annular band to expand and contract in response to a current or potential difference.