68 results about "Normal blood volume" patented technology

The invention relates to the technical field of hemodialysis, and discloses a hemodialysis ultrafiltration amount adjusting system based on multi-parameter self-adaptive control, which is used for solving the problem of insufficient prediction and prevention precision of a hemodialysis induced hypotension risk in a traditional system. According to the method, firstly, multi-parameter physiological data of the blood volume, the blood pressure and the ion concentration are synchronously collected in the whole dialysis process, then a physiological state data set is constructed through unified standardization and correlation matching, related change modes of the blood volume and the blood pressure are extracted, and ion deviation is superposed to form comprehensive risk characteristics; the risk characteristics are compared with a preset threshold value through trend analysis, the weight of each risk component is adjusted in a self-adaptive mode, a hypotension risk trend index is generated, the ultrafiltration rate is dynamically adjusted in a graded mode according to the indexes, the indexes are coupled with a real-time physiological data feedback closed loop, and therefore the prediction precision and the regulation and control refinement level of dialysis-induced hypotension are improved.

The invention is suitable for the technical field of bio-photonics, and provides a capillary refilling time self-adaptive measurement system and method, and the system comprises a negative pressure adsorption module, a step release module, a modulation module, a detection module, a demodulation module, a signal processing module and a main control unit. Standardized microcirculation stimulation is realized through negative pressure adsorption and step release; adopting a frequency domain modulation and demodulation technology to obtain the phase and the amplitude of the optical signal, and inverting an absolute absorption coefficient and a reduced scattering coefficient by utilizing a frequency domain diffusion equation; and selecting an absolute absorption coefficient under equal absorption point wavelength as a blood volume index, fitting a recovery curve through a system identification model, and calculating to obtain self-adaptive capillary refilling time. According to the collaborative scheme, the problems that in the prior art, stimulation is not standard, the result is greatly influenced by skin color and temperature, and absolute parameter support is lacked are solved, and objective and accurate measurement which is high in repeatability, cross in skin color and resistant to environmental interference is achieved.

The invention discloses a production method and system of a sanitary towel with a self-adaptive temperature adjustment function, and relates to the field of sanitary towels. And obtaining physical sign data, blood volume and motion images. And based on the physical sign data, the blood volume and the motion image, predicting a human body state to obtain a menstrual state category. And based on the menstrual state category and the human body temperature, obtaining an adjustment temperature. And recording the body state through the neural network. According to the female menstrual period nursing product integrated with the intelligent temperature control system, through real-time monitoring and intelligent adjustment, the technical effects that the local optimum temperature can be maintained, menstrual period discomfort is relieved, and the comfort level and the health management level are improved are achieved.

This application relates to a blood pump, comprising a primary pumping device, a first catheter, a secondary pumping device, and a second catheter connected in sequence. The primary pumping device has a first inlet and a first outlet, and the secondary pumping device has a second inlet and a second outlet. The secondary pumping device includes a secondary cannula, which has a proximal end, a distal end, and an enlarged portion. The proximal end is adjacent to the second catheter and has a second outlet. The distal end is connected to the first catheter and has a second inlet. The two ends of the enlarged portion are smoothly transitioned to the proximal end and the distal end, respectively. This blood pump increases the blood volume pumped by the secondary pumping device, allowing most of the blood in the aorta to be accelerated by the secondary pumping device, thus significantly improving the pumping efficiency of the secondary pumping device.

The utility model belongs to the technical field of medical instruments, and particularly relates to a bloodletting device. In the bloodletting device, one end of a drainage tube is connected with a puncture needle through a three-way connector, the other end of the drainage tube is communicated with a drainage bag, and a peristaltic pump is sleeved with the middle of the drainage tube; the puncture needle is punctured into a vein of a patient, the pump head of the peristaltic pump is used for extruding the drainage tube to generate negative pressure in the drainage tube, blood is pumped out of the vein at a constant speed, the stable bloodletting effect is achieved, it is guaranteed that one-time bloodletting amount is sufficient, and the ideal treatment effect is achieved.

A system includes: a dialysis system configured to provide a dialysis treatment for a patient; an optical monitoring system in communication with the dialysis system, wherein the optical monitoring system is configured to obtain measurements of the patient's hematocrit, oxygen saturation and / or blood volume change during the dialysis treatment, wherein the measurements are indicative of a double pool refill rate for the patient during the dialysis treatment; and a massaging system in communication with the dialysis system, wherein the massaging system is configured to provide massaging for the patient during the dialysis treatment, wherein providing massaging for the patient includes running a massage sequence taking into account the measurements obtained by the optical monitoring system.

An apparatus for blood pressure monitoring comprises: a blood vessel deformation detection sensor unit for monitoring blood volume changes and blood flow in blood vessels of a part of the user's body; a ballistocardiogram sensor unit installed adjacent to the user's back to measure the user's heartbeat; a blood vessel analysis unit for receiving signals from the blood vessel deformation detection sensor unit, analyzing them, and generating a graph; a ballistocardiogram analysis unit for receiving signals from the ballistocardiogram sensor unit, analyzing them, and generating a graph; a calculation unit for receiving data from the blood vessel analysis unit and the ballistocardiogram analysis unit and deriving at least one parameter; and a machine learning unit for receiving data on the parameter from the calculation unit and performing machine learning to derive blood pressure values.

A sensor device or system for performing a blood pressure measurement comprises a finger abutment surface, a first sensor operative to sense blood volume pulses in a finger pressed on the finger abutment surface, a second sensor operative to sense a force or pressure with which the finger is pressed on the finger abutment surface, and processing circuitry operative to process amplitudes of the sensed blood volume pulses and the sensed force or pressure with which the finger is pressed on the finger abutment surface to determine an absolute blood pressure.

A method of cardiac treatment to provide a synergetic therapeutic effect of lowering the hyperactive sympathetic response observed in microvascular disease (MVD) and heart failure (HF) pathologies and promoting cardiac remodeling of left ventricular hypertrophy in a patient. The method may include ablating renal sympathetic nerves of the patient to reduce sympathetic afferent and efferent activity to the kidney, thereby reducing blood pressure, and ablating a greater splanchnic nerve to reduce stressed blood volume with exertion. The method may include ablating renal sympathetic nerves of the patient to reduce sympathetic afferent and efferent activity to the kidney, thereby reducing blood pressure and at least one of: ablating pulmonary artery nerves of the patient to reduce cardiac sympathetic activity; and ablating pulmonary vein nerves of the patient to reduce arrhythmias.

The utility model discloses a blood pad blood volume counting and counting device, a lifting belt of each blood pad is provided with an electronic tag, the blood pad blood volume counting and counting device comprises an electronic scale and a carrying disc, the electronic scale comprises a shell, a weighing table and a display table, and the weighing table is arranged on the top surface of the shell and located on the rear side of the shell; the display table is arranged on the top surface of the shell and is positioned on the front side of the shell; the carrying disc is suitable for being placed on the weighing table and is used for storing a used blood pad; the electronic scale further comprises a supporting table used for supporting the lifting belt of the blood pad, and the supporting table is provided with a tag reader used for reading the electronic tag. The display table is configured to be capable of displaying the total blood content of the blood pads and the number of the blood pads. According to the counting and counting device for the blood volume of the blood pad, the dual functions of counting the blood pad and measuring the blood volume can be automatically completed, and the efficiency and the accuracy of measuring the blood volume in the operation process are improved.

The invention provides computer equipment for executing an inferior vena cava ultrasonic image real-time analysis and evaluation method in hemodialysis, the computer equipment comprises a memory, a processor and a computer program, when the processor executes the program, inferior vena cava ultrasonic image data in the hemodialysis process is obtained, the delay duration of inner diameter contraction response is recognized, and the delay duration is calculated; determining a latency plateau period duration based on a time period in which the inner diameter of the blood vessel is maintained relatively stable after the liquid removal speed is changed; according to the latency plateau period duration, when the blood vessel wall rebound speed is higher than the inner diameter contraction speed, high-elasticity reserve is recognized, and according to the inner diameter fluctuation range corresponding to the high-elasticity reserve, the blood volume safety range and the contraction speed threshold value are obtained; acquiring a blood volume measurement value at an ultrafiltration rate intervention time point, triggering reverse adjustment when the blood volume measurement value exceeds a blood volume safety range, and extracting a stable inner diameter contraction speed after the blood volume is stable.

The invention relates to the technical field of medical instruments, and provides a relative blood volume monitoring method and device for a hemodialysis pipeline based on double optical paths, the hemodialysis pipeline comprises a narrow-diameter section and a wide-diameter section which are connected, and the relative blood volume monitoring method comprises the following steps that S1, in dialysis treatment, red light and infrared light are adopted to irradiate the narrow-diameter section of the hemodialysis pipeline, and the narrow-diameter section of the hemodialysis pipeline is irradiated to obtain a blood volume monitoring result; the absorbance delta 1 red of the red light of the narrow-diameter section and the absorbance delta 1 infrared of the infrared light of the narrow-diameter section are calculated; s2, red light and infrared light are adopted to irradiate the wide-diameter section of the hemodialysis pipeline, and the absorbance delta 2 red of the red light of the wide-diameter section and the absorbance delta 2 infrared of the infrared light of the narrow-diameter section are calculated; s3, constructing an anti-oxyhemoglobin saturation change interference factor delta D red of the red light based on the delta 1 red and the delta 2 red; constructing an anti-oxyhemoglobin saturation change interference factor delta D infrared of the infrared light based on the delta 1 infrared and the delta 2 infrared; and S4, calculating the relative blood volume RBV based on the delta D red and the delta D infrared. The method has the advantage that accurate non-invasive monitoring of the relative blood volume is achieved.

The present application provides a kind of optical signal detection and processing method and device, and the physiological signal of optical detection is obtained by detecting blood volume change in human tissue blood vessel through photoelectric sensor in the working process of optical equipment, it is characterized in that, the method includes the following steps in the computing module of the optical equipment: set a data buffer zone, the data buffer zone can store the physiological signal of optical detection of at least 3 predetermined time units;Acquisition and calculation step, the each DC component of the physiological signal of optical detection collected is stored in the data buffer zone, the variance of the value of the DC component is calculated, and the first waveform reference index value is obtained;Comparison step;The first waveform reference index value is compared with the pre-stored reference index value range;Determination step, if the first waveform reference index value is greater than the maximum value of the reference index value, then the signal of the output device is off;If the first waveform reference index value is not greater than the maximum value of the reference index value, continue to collect new physiological signal of optical detection, then the acquisition and calculation step is executed.

The utility model relates to a device for preparing platelet-rich plasma with less blood volume. The device comprises a preparation tube unit, an upper tube cover unit, an isolation unit and a lower tube cover unit, the platelet-rich plasma preparation device has the advantages that by changing the structure of the preparation tube unit, the platelet-rich plasma preparation device can be suitable for treatment of small animals or pets; the volume of blood contained in the preparation tube unit is reduced, so that the centrifugation time is shortened, and the risks of infection and blood coagulation are reduced; besides, after the blood is centrifugally separated, a lower tube cover unit is arranged and is in threaded connection with a preparation tube unit, so that the lower tube cover unit can be rotated to adjust the volume of a fourth cavity of the preparation tube unit, the buffy yellow layer by layer is positioned in a third cavity, and the plasma is completely positioned in a second cavity of the preparation tube unit; therefore, subsequent extraction by medical staff is facilitated.

The invention relates to the technical field of medical health, in particular to a method and system for predicting the risk of hypotension in dialysis, and the system comprises a data collection module which is used for obtaining the operation parameters of dialysis equipment and the physical sign parameters of a patient; the bidirectional coupling modeling module is used for constructing a bidirectional coupling model between the patient and the dialysis equipment based on the dialysis equipment operation parameters and the patient sign parameters; the closed-loop feature extraction module is used for evaluating closed-loop response feature parameters of the human body and dialysis equipment based on the bidirectional coupling model; the risk prediction module is used for constructing a hypotension risk prediction model based on the dynamic change of the closed-loop response characteristic parameters; and the risk early warning module is used for realizing real-time early warning of the hypotension risk in the dialysis process. According to the method, the accuracy and reliability of hypotension risk early warning are effectively improved by quantitatively describing the influence of abnormal operation of dialysis equipment on hemodynamics of a patient and disturbance feedback of blood volume change of the patient on an equipment fluid control loop.

The present application belongs to the field of intelligent medical treatment, and particularly relates to a method, device, medium and program product for predicting RMPP based on lung microvessel changes. The method comprises the following steps: S101: acquiring CT images of a pediatric MPP patient; S102: extracting the CT images to obtain quantitative PBV parameters, wherein the quantitative PBV parameters comprise BV10%, wherein BV10% refers to the percentage of blood volume in blood vessels with a cross-sectional area greater than 10 mm2 in total lung blood volume; and S103: if BV10% is higher than a first threshold value, determining that the pediatric MPP patient has a high risk of developing into RMPP, otherwise outputting a prediction result that the pediatric MPP patient has a low risk of developing into RMPP. The present application discovers the prediction effect of microvessel changes in CT on the occurrence and development of RMPP by quantitatively measuring the microvessel changes, realizes the clinical value of early diagnosis of RMPP, and thus drives early treatment in the clinic.

A method embodiment includes generating, via a sensor of a computing device, a signal representing vibrations originating from a blood vessel of a subject and decomposing the signal into one or more first intrinsic oscillatory modes and one or more second intrinsic oscillatory modes. The one or more first intrinsic oscillatory modes have respective oscillation frequencies that are less than respective oscillation frequencies of the one or more second intrinsic oscillatory modes. The method includes obtaining an intensity spectrum of the one or more first intrinsic oscillatory modes over a range of frequencies and using the obtained intensity spectrum to determine a blood volume status of the subject. Another method embodiment includes using the one or more second intrinsic oscillatory modes to determine one or more mechanical properties of the blood vessel or tissue adjacent to the blood vessel.

Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include the use of an RBC flocculant, for example polyDADMAC, and an approximate blood hematocrit from the type of animal blood being evaluated, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal blood hematocrit, and a calculated RBC packing ratio “η” value for the collection device. A collection device with a BIP is disclosed. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

This application relates to a nonlinear recursive calculation and monitoring method for relative blood volume. The method includes acquiring prior baseline parameters, discrete laboratory data sequences, and real-time physiological data streams; performing nonlinear dimensional compression mapping on continuously fluctuating parameters to generate dynamic mapping factors; calculating biochemical characteristics for discrete sampling parameters and triggering neutral degradation assignment to generate static modulation factors when anomalies occur; constructing a nonlinear decaying negative feedback term based on the previous blood volume state value and performing truncation processing to generate an adaptive saturation factor; fusing the above factors to update the unconstrained blood volume; and using numerical pinch intervals for physical boundary constraints to obtain the relative blood volume monitoring value. This application has the advantages of improving the system's anti-interference capability in high-frequency data sampling environments, blocking the propagation of missing data, and effectively suppressing system computational divergence and numerical oscillations.

The utility model provides a disposable blood metering hole towel which is suitable for a delivery scene and comprises a hole towel body and a metering bag fixedly arranged on one side of the hole towel body. The disposable blood metering orifice towel is characterized by further comprising a maintaining assembly, the maintaining assembly is a magnetic or / and air bag assembly and is installed at a bag opening of the metering bag. The maintaining assembly is used for maintaining the metering bag in an open state under the triggering of external force. When the hole towel is used, the hole towel is laid on the body of a patient, a medical worker can trigger the maintaining assembly to be converted into a maintaining state by applying external force to the maintaining assembly, namely, the metering bag is maintained to be in an open state, so that in the medical activity process, the metering bag can be always in the open state, and excrements of the patient are collected; medical staff do not need to pull the bag opening of the metering bag all the time, and use convenience is improved.

The present application relates to the field of electrical impedance imaging, and discloses a regional lung perfusion delay time analysis method, an electronic device and a storage medium. A dynamic image of conductivity change caused by blood perfusion in a human thoracic cavity is obtained. A blood perfusion image of a heart region and a blood perfusion image of a lung region are separated. A reference curve of conductivity change of the heart region is obtained according to the dynamic image of blood perfusion conductivity change and the blood perfusion image of the heart region. A conductivity change curve of each pixel point in the blood perfusion image of the lung region is obtained according to the dynamic image of blood perfusion conductivity change and the blood perfusion image of the lung region. The conductivity change curve is divided by a sliding time window, and a regional lung perfusion delay time is calculated in each time window. The time resolution advantage of electrical impedance imaging technology is fully utilized, and the time delay of the time when the local blood volume of the lung reaches the maximum relative to the end of the ventricular diastole is reflected by calculating the regional lung perfusion delay time.

This application relates to a sample analyzer and a sample analysis method. A sampling distribution module is configured to collect blood samples and allocate a portion of the collected blood samples to an erythrocyte sedimentation rate (ESR) detection module. The ESR detection module's optical detection device detects the ESR of the blood sample by detecting the degree of light absorption or scattering by a portion of the blood sample. When the detection mode is in the first mode, the control module controls the sampling distribution module to allocate a first amount of the blood sample to the ESR detection module and controls the ESR motor to drive the first amount of the blood sample to the detection location at a first speed. When the detection mode is in the second mode, the control module controls the sampling distribution module to allocate a second amount of the blood sample to the ESR detection module and controls the ESR motor to drive the second amount of the blood sample to the detection location at a second speed. The second amount is smaller than the first amount, and the second speed is smaller than the first speed. This ensures that the precision of the ESR detection remains essentially constant under different blood volumes.

This invention discloses a highly sensitive method for detecting troponin I. This method utilizes the reusable nature of a biosensor to perform multiple fluorescence signal reads. Based on these multiple reads, it selects the most accurate concentration range for determining concentrations in the low-to-medium concentration range, achieving higher resolution detection results in both low and medium concentration areas. Furthermore, it incorporates chemiluminescence detection, employing higher-resolution chemiluminescence to determine the final concentration in the high-concentration region. Ultimately, this method achieves better resolution detection results across high, medium, and low concentration regions, enabling accurate identification of sample concentrations across all concentration ranges. It boasts a sensitivity of 0.824 ng / L and a detection range of 0.824 ng / L–100,000 ng / L. The method significantly reduces sample volume, requiring only 20 μL for accurate detection, thus reducing blood volume and improving blood collection efficiency in physical examinations.

Described herein are systems, methods, and computer-readable medium for detecting a perfusion abnormality of a subject. In one embodiment, a method includes the following: obtaining, by dynamic radiography, imaging data for a dynamic series of a plurality of x-ray images that include areas of a subject corresponding to pulmonary vasculature; identifying, based on the imaging data, a dynamic signal corresponding to changing blood volume during the cardiac cycle of the subject; decomposing the dynamic signal into periodic components in frequency space; identifying, from the periodic components in frequency space, signals oscillating at the heart rate of the subject; generating, based on the identified signals oscillating at the heart rate of the subject, a perfusion map representation corresponding to pulmonary tissue perfusion in the subject; and detecting, based at least in part on the generated perfusion map representation, a perfusion abnormality of the subject.

The invention discloses a method for evaluating myocardial micro-blood flow based on ultrafast ultrasonic imaging and ultrasonic equipment. The method comprises the following steps: (1) acquiring an ECG signal and identifying a cardiac cycle; (2) reading an ultrasonic image RF data sequence; (3) n frames of data are selected and recombined into a two-dimensional array, and singular value decomposition is carried out; (4) selecting a filtering interval in the energy-rank spectrum to carry out space-time filtering; (5) carrying out pixel registration and phase alignment on the obtained frame ultrasonic image; (6) selecting n frames of data again at an interval of one frame for filtering, registering and leveling, and repeating in sequence to obtain a group of robust quantitative ultrasonic image data sequences; (7) calculating the instantaneous energy of the complex signal after space-time filtering; (8) calculating a micro blood volume curve; and (9) calculating a filling peak value, a filling / clearing speed and an area under the curve. According to the method, the spatial-temporal evolution of myocardial micro-hemodynamics can be accurately analyzed in a single cardiac cycle, and the myocardial blood flow state can be accurately and dynamically evaluated.

The invention provides a method and a device for realizing blood demand prediction based on an AI large model, which can overcome the problems of limited accuracy and poor adaptability caused by rule solidification and incapability of self-evolution of a traditional expert system, thereby accurately realizing blood demand prediction. The method comprises the following steps: acquiring feature data related to blood demands of a patient to be predicted; determining whether the to-be-predicted patient needs blood transfusion according to the feature data; if it is determined that the to-be-predicted patient needs blood transfusion, the predicted blood volume of the patient is determined based on the trained prediction model; and if it is determined that the to-be-predicted patient does not need blood transfusion, determining that the predicted blood volume of the patient is zero.

The invention relates to a dried poultry blood spot swab and application, the dried poultry blood spot swab comprises a blood sampling area, a transition area and a handheld area, the blood sampling area comprises a spherical blood sampler and a circular truncated cone, and the surface of the spherical blood sampler is completely covered with flocking. According to the dried poultry blood spot swab, the dried poultry blood spot swab is divided into the blood taking area, the transition area and the handheld area, the surface of a spherical blood taking device in the blood taking area is completely covered with the flocking, the flocking is adopted for blood suction, the handheld area and the blood taking area can be isolated through the transition area, the environmental pollution probability is reduced, and when the dried poultry blood spot swab is adopted for blood taking, the sampling wound surface is small, and the blood taking amount is small; the growth of poultry is not influenced, and rapid and large-scale extraction of poultry blood nucleic acid can be realized.

A method for collecting blood components from a subject using an automated blood collection system includes: separating plasma from whole blood received from the subject; initiating an alert when the predicted cumulative volume loss is greater than a configured removal level, the predicted cumulative volume loss depending on a cumulative volume comprising the separated plasma volume, the configured removal level defined by a pre-selected maximum value or a low blood volume level for the subject; and in response to feedback and alerts from an operator of the automated blood collection system, ending the process of collection, continuing collection, or initiating separation of platelets and erythrocytes.

The invention discloses a liquid management and volume monitoring system for continuous kidney replacement therapy of critical patients, which comprises a volume monitoring module, a microcirculation monitoring module, a data processing core module, an intelligent regulation and control module and a man-machine interaction module which are in two-way communication connection through a data bus, and the data processing core module is a system control center; the volume monitoring module comprises a noninvasive blood volume detection unit and an individualized infusion regulation and control unit. Through closed-loop automatic adjustment of the contact force of the probe, constant contact pressure between the probe and the skin of a patient is ensured, and imaging distortion caused by abnormal pressure is avoided; meanwhile, through three-dimensional coordinate monitoring and displacement influence coefficient quantification of patient displacement, in combination with an invalid data filtering algorithm based on a convolutional neural network, invalid data generated by interference are automatically filtered, the invalid data recognition accuracy is improved, the reliability of microcirculation monitoring data and blood volume monitoring data is greatly improved, and clinical misjudgment is avoided.