When performing drainage in an AV
connection type blood circuit, it is determined that the blood circuit is in an AV connection state. A
blood purification device includes a blood circuit having a
blood withdrawal side circuit and a blood return side circuit, one end of the
blood withdrawal side circuit and one end of the blood return side circuit being connected to each other by a blood purifier, and the other end of the
blood withdrawal side circuit and the other end of the blood return side circuit being connected to each other, whereby a
closed circuit can be formed; a
blood pump provided in the blood circuit; a flow
path switching section capable of being switched between an open state in which a fluid can flow through one end of the blood withdrawal side circuit and one end of the blood return side circuit, and a
closed state in which the fluid cannot flow; a
pressure detection section for detecting an
internal pressure of the blood circuit; and a control section that, when the blood circuit is in a state in which the
closed circuit is formed, performs a drainage process of draining residual liquid in the blood circuit to a predetermined
discharge location. The control section performs the following control: in the
closed state, after a
pressure difference is generated between the blood withdrawal side circuit and the blood return side circuit by rotation of the
blood pump, the open state is switched to, and the
pressure difference is monitored based on a detection result of the
pressure detection section to determine whether the blood circuit is the
closed circuit.