30 results about "Blood markers" patented technology

An introducer having a sheath, a guide rod, and at least two wire stabilization guides being elongated members, at least a portion of which extend from an end of the sheath. The portions of the wire stabilization guides include a retention device formed on the portion of the wire stabilization guides that extend from the end of the sheath. The retention device is adapted to selectively expand outwardly, stabilizing the sheath relative to a wound site. The guide rod may be provided with one or more blood marking lumen, having a distal port, for identifying the depth of insertion into an artery or vein based on the presence or absence of pressurized blood in the lumen.

The present invention is related to methods of early diagnosis of ovarian cancer in a patient by determining serum levels of blood markers using a novel LabMAP™ technology (Luminex Corp., Austin, Tex.), which allows for simultaneous measurement of the blood markers in serum. The panel of blood markers offers extremely high predictive power for discrimination of ovarian cancer from both healthy control patients and from patients with benign pelvic/ovarian tumors. The methods of the present invention allow for rapid, early diagnosis of ovarian cancer with extremely high sensitivity and specificity to be clinically useful in disease diagnosis.

The present invention provides methods and materials related to the detection of colorectal neoplasm-specific markers in or associated with a subject's stool sample. In particular, the present invention provides methods and materials for identifying mammals having a colorectal neoplasm by detecting the presence of exfoliated epithelial markers (e.g., human DNA, tumor associated gene alterations, tumor associated proteins) and blood markers (e.g., homoglobin, serum proteins) in a stool sample obtained from the mammal.

The invention relates to the field of biological information, and discloses a method for predicting age by using a blood marker, which comprises the following four steps of: collecting blood marker data, preprocessing the data, establishing and evaluating a model and testing the model. Compared with other methods and markers, the method has the advantages that the blood marker serves as an evaluation object of the physiological age, the individual aging condition can be reflected more comprehensively, the aging level can be explained more comprehensively, meanwhile, the selected blood marker is predicted through the machine learning model, the process is more intelligent, and the result is more accurate; the selected blood marker, namely a blood biochemical index, is the most common indexin clinical and physical examination institutions, and is low in acquisition difficulty, low in cost and high in interpretation degree.

The invention discloses an information prompting method and a mobile terminal so that the user can be warned to pay attention to the own health better when using a mobile terminal. The method comprises the following steps that: after a target user is detected to operate a mobile terminal, blood indicator data of the target user are collected; the blood indicator data are compared with preset healthy blood indicator data of the target user; and when the comparison result meets a non-health condition, the mobile terminal carries out health information prompting.

The invention relates to the field of biological information, and discloses a method for predicting gender by using a blood marker. The method comprises the following four steps of: collecting blood marker data, preprocessing the data, establishing and evaluating a model and testing the model. Compared with other methods and markers, the selected blood marker, namely a blood biochemical index, isthe most common index in clinical and physical examination institutions, the acquisition difficulty is low, the cost is low, and meanwhile, a machine learning model is used for calculating the selected blood marker, so that the process is more intelligent, and the result is more accurate.

The invention discloses a P16-based lung cancer postoperative comprehensive rehabilitation management method, which comprises a theoretical analysis module, a system establishment module, a case analysis module and PG-SGA nutrition assessment. The theoretical analysis module comprises NSCLC blood marker screening, a nutrition evaluation model and intervention measures, a physical strength evaluation model and intervention measures, a psychological evaluation model and intervention measures, and a traditional Chinese medicine constitution evaluation model and intervention measures, and the NSCLC blood marker screening comprises Meta-based NSCLC blood marker analysis and MDR-based blood marker screening. The nutrition evaluation model and the intervention measure adopt an FG-SGA evaluation model, and the physical power evaluation model and the intervention measure adopt an ECOG evaluation model. According to the P16-based lung cancer postoperative comprehensive rehabilitation management method, after a patient is discharged from a hospital, the patient can evaluate personal nutrition, psychology, physical strength and other conditions anytime and anywhere through a mobile phone APP, and professional and normative intervention measures are obtained according to personal evaluation results without extra expenditure.

The invention discloses a multiplex detection kit for neonatal disease screening and a preparation method and a use method thereof. The multiplex detection kit comprises a buffer solution, at least two reaction cups, acridinium ester marker microspheres, a calibration product, a quality control product, an excitation solution, a concentrated washing solution and a hemolytic agent, the reaction cup is a micropore of which the inner surface is coated with a target antibody or antigen conjugate; the target antibody or antigen conjugate is an anti-TSH antibody protein, thyroxine T4 coupled bovine serum albumin, 17 alpha-hydroxyprogesterone coupled bovine serum albumin and an anti-GAA antibody protein. According to the invention, one kit is used for combined screening of multiple (2-8) blood markers, so that the preparation work is greatly simplified, errors caused by manual operation are reduced, and the working efficiency is improved; the high performance of quantitative detection is ensured by applying a chemiluminescence labeling immunoassay technology and a fluorescence analysis method which take acridinium ester as a marker.

The invention provides a kit for joint detection based on microspheres with different fluorescence intensities. The kit comprises a microsphere reagent, and a labeled second antibody or antigen; the microsphere reagent is N microspheres with the same diameter and different fluorescence intensity codes, the surfaces of the N microspheres are correspondingly coated with first antibodies or antigens of N blood markers, and N is an integer between 2 and 5; and the labeled second antibody or antigen comprises N second antibodies or antigens of blood markers, fluorescein is labeled on the second antibodies or antigens, and the binding sites of the first antibody or antigen and the corresponding antigens or antibodies and the binding sites of the second antibodies or antigens and the corresponding antigens or antibodies are different. The invention also relates to a method for joint detection based on microspheres with different fluorescence intensities. The kit provided by the invention can realize specific detection of five pathogen antigens/antibodies in blood transfusion through one-time reaction, and the detection process is simple, convenient and accurate.

The invention discloses an application of GSK-3beta as a blood marker in the preparation of a diagnostic reagent for mental disorders, especially autism spectrum disorders (ASD). GSK-3beta can be usedas an ASD early-diagnosis reagent, and a detection time window is 0-3 months for newborns. The non-invasive auxiliary diagnosis of ASD can be carried out by only using a small amount of blood sample,the large-scale infant ASD screening is facilitated, and early discovery, early intervention and early treatment of ASD are facilitated.

The invention provides a device for detecting diagnostic blood markers as early as half an hour upon an acute myocardial infarction symptoms onset.

Presented herein are methods of identifying a subject who has, or is at risk of developing Alzheimer's disease comprising determining a presence or amount of 2-aminoethyl dihydrogen phosphate or taurine in the blood, or a blood product, obtained from the subject. Also presented herein are method of preventing, treating or delaying the onset of Alzheimer's disease.

The present invention provides methods for early diagnosis of amyotrophic lateral sclerosis (ALS) and for determining the efficacy of a treatment for ALS in an ALS patient, i.e., monitoring ALS progression, utilizing cellular blood markers; as well as kits for carrying out these methods.

The present invention relates to a method for detecting bowel transplant rejection.

The detection method according to the invention is a method for the in vitro detection of bowel transplant rejection comprising steps for measuring the concentration at markers in a fluid sample, calculating the difference for each marker with a reference concentration, comparing for each marker the difference with a discriminatory threshold variation and assigning a score.

The present invention is particularly applicable in the medical field, more specifically in the field of transplantations and transplant rejection detection.

The invention discloses a system for predicting lignified pectoral muscle of broiler chicken through blood markers and application, a regression equation for predicting the lignified pectoral muscle of the broiler chicken is established through the blood markers, whether the pectoral muscle of the broiler chicken is lignified or not is predicted according to the regression equation, and the blood markers comprise any one or three of the content of pO2, the content of sO2 and the content of pCO2 in blood. The system provided by the invention comprises a data acquisition module used for acquiring the content of blood markers in broiler chicken sample blood; the data processing module is used for substituting the received blood marker content data in the data acquisition module into a regression equation for data processing to obtain a regression value; the data studying and judging module is used for receiving the regression value obtained by processing of the data processing module and studying and judging whether the breast muscle of the meat chicken is lignified or not; and the output module is used for outputting the research and judgment result and displaying the research and judgment result on the processor.