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3 results about "Proclin" patented technology
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ProClin 150, 200, 300 is a broad spectrum antimicrobial suited as a preservative for in vitro diagnostic assays. It does not inhibit most enzymes, antibody binding, nor interfere with ISE electrodes. ProClin is corrosive and can cause eye and skin burns, allergic skin reaction and dermatitis, may be harmful if swallowed, absorbed through skin, or inhaled. It is safe to dispose of at recommended use level. When disposing reagents containing ProClin 150, 200, 300, flush drains with copious amounts of water to dilute the components below biologically harmful levels; many waste water handling systems can handle the ProClin levels, as is. [Dow Microbial Control]
A preservation solution, an adiponectin detection kit, its preparation method and application
PendingCN122084903APreserve immune activityEnhanced measurable fluorescence signalDead animal preservationBiological testingCelluloseActive agent
This invention relates to the field of biodetection technology, disclosing a preservation solution, an adiponectin detection kit, its preparation method, and its application. The preservation solution comprises Tris, trehalose, Tween 20, sodium caseinate, PVP-10, Proclin-300, TX-100, surfactant S13, and glycine. This specific formulation effectively prevents quantum dot aggregation and maintains protein activity for a long time. The adiponectin detection kit is based on quantum dot immunofluorescence chromatography technology and includes components such as a sample pad, a release pad, and a nitrocellulose membrane. The release pad is simultaneously coated with quantum dot-labeled antibodies and unlabeled detection line antibodies, and the quantum dot-labeled antibodies are coupled in a cascade manner of "quantum dot-streptavidin-biotinylated antibody". This invention, through liquid dialysis linking technology and a unique release pad antibody premixing process, utilizes the signal amplification effect of the biotin system and the principle of homogeneous reaction, significantly improving the sensitivity, accuracy, and reagent stability of the detection.
Owner:CHONGQING XINSAIYA BIOTECHNOLOGY CO LTD
A cell climbing sheet processing reagent for a lupus nephritis / paranephritis antibody spectrum detection kit (cellular immunofluorescence method), a method thereof and application thereof
The application provides a cell climbing sheet processing reagent for a Ranvier node / paranode antibody spectrum detection kit (cellular immunofluorescence method), a method and application thereof, and relates to the technical field of in-vitro detection. The cell climbing sheet processing reagent comprises a cell fixing solution with a specific composition and an antigen repair composition after cell fixing, wherein the cell fixing solution is composed of paraformaldehyde, formaldehyde, acetic acid, raffinose and a buffer solution, and the antigen repair composition after cell fixing is composed of ammonium sulfate, hydroxylamine hydrochloride, Brij 78, TCEP, ProClin 300 and a buffer solution. Through the synergistic effect of the two, the natural conformation of the target antigen is maximally retained, and non-specific interference is reduced, so that precise and efficient detection of the Ranvier node / paranode antibody spectrum NF155, NF186, CNTN1, CASPR1 and MAG can be realized, the clinical diagnosis demand is met, and reliable technical support is provided for precise typing of autoimmune Ranvier node disease.
Owner:HEMAI (TIANJIN) MEDICAL TECHNOLOGY CO LTD