21 results about "BENZALKONIUM BROMIDE" patented technology

The invention relates to the technical field of aquaculture disinfectants, and discloses a composite benzalkonium bromide disinfectant preparation device for aquaculture, which comprises a mixing barrel, the top of the mixing barrel is provided with a top cover, the top of the top cover is provided with a quantifying mechanism, the quantifying mechanism comprises a quantifying barrel, the quantifying barrel is fixedly connected to the top of the top cover, and the quantifying barrel is fixedly connected to the top of the top cover. The bottom of the quantifying barrel penetrates through the top cover, a plurality of storage tanks are fixedly connected to the top of the inner side of the quantifying barrel at equal intervals, a partition plate is fixedly connected to the lower middle portion of the inner side of the quantifying barrel, and the bottoms of the storage tanks penetrate through the partition plate. A first motor drives a pushing disc to rotate, a notch of the pushing disc can be matched with a single separation blade, and a spring can push the separation blade to move, so that the bottom of a corresponding storage tank is opened, and raw materials in the storage tank enter a quantitative barrel; different raw materials in different material storage tanks are quantified in the barrel according to the proportion.

The present invention provides a deodorant for air disinfection and deodorization and a preparation process thereof, belonging to the field of air purification technology; the deodorant comprises the following components: a composite deodorizing material, composite essential oil microcapsules, a surfactant, benzalkonium bromide, and water. The present invention comprises the following components: calcium nitrate tetrahydrate and diammonium hydrogen phosphate are first mixed and dissolved, and cetyltrimethylammonium bromide and ammonia water are added to prepare a mesoporous nano-hydroxyapatite precursor suspension, and then a zinc nitrate solution is added, followed by a hydrothermal reaction and calcination to prepare a composite carrier material. When the composite essential oil is loaded into the composite carrier material by a vacuum impregnation method, not only can the composite essential oil have a sustained-release effect, thereby improving the long-lasting deodorizing effect of the deodorant, but also more adsorption sites can be provided for the composite essential oil, thereby significantly increasing the loading rate of the composite carrier material for the composite essential oil, thereby improving the deodorizing effect of the deodorant.

The present invention discloses a compound foam-type long-acting disinfectant containing citric acid, its preparation method and application. The disinfectant includes the following components by weight percentage: citric acid 0.5% to 5.0%, benzalkonium bromide 0.5% to 5.0%, decanium bromide 0.5% to 5.0%, glutaraldehyde 0.25% to 2.5%, polyhexamethylene biguanide 0.5% to 5.0%, cosolvent 3.0% to 15.0%, penetrant 0.1% to 0.5%, foam emulsifier 0.5% to 5.0%, stabilizer and citric acid can form a buffer system, maintain a pH value of 3.0 to 5.0, and sterile water is supplemented to 100%. The compound disinfectant of the present invention has a synergistic or additive effect, killing all pathogenic microorganisms of animal origin including bacteria, viruses, mycoplasmas, fungi, etc. in the breeding environment, with a sterilization efficiency of 100%.

The invention discloses skin mucosa maintenance liquid capable of killing fungi and HPV (human papillomavirus) as well as a preparation method and application of the skin mucosa maintenance liquid, and belongs to the technical field of sterilization and virus removal. The skin mucosa maintenance liquid is prepared from octanol ether, benzalkonium bromide, phenoxyethanol, yermate, parachlorometaxylenol, taetinic acid, chitosan, keratinase, fluconazole, glycerol, borneol, menthol, absolute ethyl alcohol and tween-40. Wherein the skin mucosa maintenance liquid has an effect of regulating apoptosis induction on abnormal cells and an effect on vaginal flora, and has an obvious inhibition effect on cervicitis and colpitis mycotica, namely an anti-inflammatory effect; meanwhile, apoptosis of cells containing HPV16 and HPV18 genes can be induced, shedding of abnormal cells is promoted, diseased cells are killed, and vaginal tissues with pathological changes are removed.

The application discloses a quercetin-chitosan nanoparticle suspension eye drop, a preparation method and application thereof. The eye drop contains the following components on the basis of 100ml of preparation: quercetin 0.001-0.006g; chitosan 0.05-0.3g; sodium tripolyphosphate 0.01-0.05g; sodium chloride 0.6-1.5g; benzalkonium bromide 0.005-0.02g; borate buffer 1-3g; and the rest is injection water, and the total amount is 100ml. Quercetin is loaded in nanoparticles formed by ion cross-linking of chitosan and sodium tripolyphosphate. The application solves the technical defects of poor water solubility and easy oxidation of quercetin by constructing a polyphenol-chitosan nanocomposite system. The application has a dual synergistic mechanism of ROS clearance and mucosa repair, significantly improves the ocular bioavailability of quercetin, and has a wide application prospect in drugs for preventing or treating dry eye.

The application discloses a bubble-assisted benzalkonium chloride heterogeneous Fenton-like catalytic degradation method and belongs to the technical field of water treatment in environmental engineering. The method uses ferric nitrate, cobalt chloride, lanthanum nitrate and biochar as raw materials, synthesizes BC / LaFeCo-LDH through a hydrothermal method, uses the BC / LaFeCo-LDH as a heterogeneous Fenton-like catalyst, and is used for activating peroxymonosulfate. Meanwhile, a solid-liquid-gas heterogeneous Fenton-like catalytic system is constructed in combination with a hydrodynamic cavitation reactor. In the system, the exposure degree of benzalkonium chloride is increased by virtue of the bidirectional action of hydrophobic bubbles and the surface of hydrophilic catalysts, the activation rate of peroxymonosulfate is significantly improved, a large amount of singlet oxygen is generated, and the degradation efficiency and reaction rate of benzalkonium chloride are effectively improved. The method provides an effective way for green and efficient degradation of benzalkonium chloride.

The invention provides a method for improving the production efficiency of weaned piglets after long-term transportation, and belongs to the technical field of livestock breeding. Comprising the following steps: (1) after transportation is completed, determining a drinking water additive according to transportation time t and transportation temperature T; the drinking water additive comprises one or more of ginger powder, an astragalus extract, vitamin C, cane sugar and cinnamyl aldehyde; (2) after the transportation is completed, performing staged feeding management on the weaned piglets; 3, within 6-8 days after transportation is completed, air aerosol is sprayed to the pig house every day; the air aerosol comprises the following components: benzalkonium bromide and rosemary essential oil. According to the method, heat stress or transportation stress possibly generated in the transportation process of the weaned piglets can be relieved, the survival rate of the piglets from the transportation completion to the nursing stage is increased, the diarrhea rate is reduced, the fattening period is shortened, and the production and economic benefits are remarkably improved.

This invention discloses a corrosion method for high-carbon pearlitic steel rails with a pre-austenite grain size. The sample test surface is polished, and during corrosion, the polished surface is completely immersed in the corrosive agent, taking care not to touch the bottom of the container to avoid affecting the corrosion effect. The corroded surface is observed periodically during corrosion. Once the corroded surface exhibits a uniform dark gray frosted state, it is removed, rinsed, and dried. Finally, excess corrosion layer is lightly polished on a polishing machine before observation. The corrosive agent includes hydrochloric acid, acetic acid, ferric chloride, benzalkonium bromide, shampoo, and deionized water. The purpose of this invention is to provide a corrosion method for high-carbon pearlitic steel rails with a pre-austenite grain size that can clearly display the pre-austenite grain boundaries, solving the problem of difficult corrosion of pre-austenite grains. Furthermore, the reagents used are stable, safe, and easy to store.

The invention discloses an aloe barbadensis leaf water composition for removing acnes and application thereof, and the composition is prepared from the following components in percentage by mass: 91 to 97 percent of aloe barbadensis leaf water, 1 to 4 percent of nicotinamide, 1 to 4 percent of arbutin, 0.1 to 0.4 percent of benzalkonium bromide and 0.1 to 0.6 percent of chlorhexidine acetate. The invention also provides a preparation method and application of the composition. The method comprises the following steps: weighing the raw materials in proportion, then mixing the aloe barbadensis leaf water, nicotinamide, arbutin, benzalkonium bromide and chlorhexidine acetate in a container, stirring and dissolving uniformly, sampling and detecting to be qualified, disinfecting and sterilizing, and finally, sealing, packaging and storing the aloe barbadensis leaf water, the nicotinamide, the arbutin, the benzalkonium bromide and the chlorhexidine acetate. The composition is used for preparing skin care products for removing acnes. The aloe barbadensis leaf water composition for removing acnes, prepared by the preparation method disclosed by the invention, adopts acnes-removing components derived from the nature, is safe in acnes removal without hurting the skin, restores the skin to a healthy state while repairing the damaged skin, and inhibits the re-breeding of acnes and bacteria.

The invention relates to a novel deodorant for removing formaldehyde, hydrogen sulfide and ammonia and application thereof in deodorant spray. The novel deodorant contains a plant source deodorant, a disinfectant, a biological desulfurizer, sesame oil, a buffer solution and a propellant, wherein the biological source deodorant is selected from one or more of tea polyphenol, a folium eucalypti extract, a bamboo leaf extract, peroxidase, tannic acid or plant straw fermentation liquor; the disinfectant is selected from one or more of potassium hypochlorite, calcium hypochlorite, glutaraldehyde, benzalkonium bromide or hydrogen peroxide; the biological desulfurizing agent is selected from one or more of hydrogen sulfide oxidase, thiocyanate enzyme, Mn / Ce-HMS, CuO-CaCO / BC, Zn-Mn / KIT-1 and sulfur oxidizing bacteria / ceramic carriers. Through the synergistic effect of a chemical method and a biological enzyme method, various harmful ingredients such as formaldehyde, ammonia and hydrogen sulfide are efficiently removed and decomposed at a time, environmental pollution is reduced, meanwhile, the disinfection and sterilization effects are achieved, operation is easy, and the deodorant spray has wide application prospects in deodorant spray.

The invention relates to a method for detecting mould in feed by an ATP (adenosine triphosphate) method, which comprises the following steps: S1, sequentially carrying out first mixing and extraction treatment on a feed sample and normal saline, and collecting supernate as an extracting solution; s2, the extracting solution and a benzalkonium bromide solution with the concentration being 0.10%-0.20% are sequentially subjected to second mixing and cracking treatment, and a cracking solution is obtained; s3, carrying out third mixing on the lysis solution and an ATP reaction reagent to obtain a solution to be detected; and S4, measuring the RLU value of the to-be-measured liquid by using a handheld ATP (adenosine triphosphate) luminoscope. The method has the advantages of high detection speed and high accuracy, and can timely detect feed mildew at the early stage and realize feed mildew prevention and control.

The intelligent hydrogel mask comprises a matrix and functional components, the matrix at least comprises 5%-10% by weight of sodium carboxymethyl cellulose, 10%-20% by weight of polyethylene glycol, 10%-20% by weight of glycerin, 10%-20% by weight of benzalkonium bromide and 10%-20% by weight of water. By adopting the technical scheme provided by the invention, the hydrogel matrix in which the weight percentage of sodium carboxymethyl cellulose is 5%-10% is utilized, so that the moisturizing performance, the antibacterial performance and the nourishing performance of the intelligent hydrogel mask can be optimal.

The invention belongs to the technical field of preparation of antibacterial preparations, and particularly relates to an antibacterial composition, an antibacterial nano-emulsion, an antibacterial preparation and application of the antibacterial composition, the antibacterial nano-emulsion and the antibacterial preparation. Through verification, the benzalkonium bromide and the chlorhexidine acetate can achieve the effect of synergistically resisting methicillin-resistant staphylococcus aureus (MRSA) by inhibiting or removing a biological membrane (cell membrane), and particularly, the nano-emulsion prepared from the benzalkonium bromide and the chlorhexidine acetate has an excellent MRSA resisting effect; the minimum inhibitory concentration (MIC) of the prepared nanoemulsion on MRSA bacteria is 1.5625 [mu] g / mL, and the minimum bactericidal concentration (MBC) of the prepared nanoemulsion on MRSA bacteria is 6.25 [mu] g / mL; in addition, the prepared nanoemulsion is low in toxicity and excellent in stability. Moreover, the antibacterial preparation disclosed by the invention is simple in preparation process, stable in quality and suitable for large-scale production, can be widely applied to infection of multiple drug-resistant bacteria of skin wounds, and has a good market application prospect.

The invention relates to the technical field of medical disinfection, and discloses an endoscope disinfectant based on synergistic interaction of polyhexamethylene biguanide and nano-silver, the disinfectant is composed of polyhexamethylene biguanide, nano-silver, sodium citrate, benzalkonium bromide and the like in an aqueous medium, and is characterized in that supramolecular micelles of a core-shell structure are formed. According to the micelle, nano-silver functionalized by sodium citrate serves as a core, polyhexamethylene biguanide serves as a shell, and benzalkonium bromide serves as a structure-directing agent to be embedded into a shell layer so as to enhance the stability. The preparation method adopts a temperature difference induced self-assembly technology, and comprises the following steps: dropwise adding a warm solution containing nano-silver and sodium citrate into a relatively cold solution containing polyhexamethylene biguanide and benzalkonium bromide at a controlled rate so as to realize ordered assembly of micelles. By constructing a stable nano structure, efficient synergy of disinfection components is realized, and the physical storage stability and particle size uniformity of the product are improved.

The invention discloses a low-residue and low-corrosion clean room floor disinfection composition for the intravenous admixture center, which is prepared by the following steps: S1, adding a proper amount of ionized water into a reaction kettle, starting stirring, adding a surfactant into the reaction kettle in the stirring process, and stirring for a period of time to obtain a basic solution; s2, slowly adding a modified disinfectant into the basic solution while stirring, adding a corrosion inhibitor, and uniformly distributing to obtain a composite disinfectant; and S3, adding a pH regulator into the composite disinfectant, adjusting the disinfection composition, and controlling the pH value to be within 7 to obtain the ground disinfection composition. The benzalkonium bromide, the silver salt, the tea polyphenol and other components in the modified disinfectant have a synergistic effect, and the microbial structure and function can be destroyed from different levels. The floor cleaning agent has good killing effects on gram-positive bacteria, gram-negative bacteria, fungi and part of viruses, can effectively reduce the number of microorganisms on the floor of the clean room of the intravenous admixture center, and ensures the sanitation and safety of the environment.

The invention relates to the technical field of aquaculture, and discloses a seawater crab industrialized breeding method which comprises the following steps: carrying out egg-carrying breeding on parent crabs to obtain egg-carrying crabs; transferring the egg-carrying crabs into a hatching barrel to obtain larvae; transferring the larvae into a seedling culture pond for seedling culture until seedlings emerge; a slow-release bactericide is adopted for egg-carrying crab and larva breeding, the slow-release bactericide is prepared from a film-forming solution and foamy copper, and the film-forming solution is prepared from polyvinyl alcohol, benzalkonium bromide, a solvent and sorbitan monostearate; according to the parent crabs bred through the method, the egg carrying rate can reach 85% or above, the embryonic development synchronization rate can reach 95% or above, the embryonic development speed is remarkably increased, and the surface parasite and sticky dirt phenomena are remarkably reduced; the slow-release bactericide adopted by the method has a continuous bactericidal effect, can continuously provide a stable bactericidal effect, and can reduce the dosage, reduce the seedling culture cost and improve the seedling culture efficiency.

The invention relates to the technical field of in-vitro diagnosis, and discloses a preparation method of full-soluble animal plasma, which comprises the following steps: S1, preparation: taking animal whole blood, mixing an anticoagulant and the animal whole blood according to a volume ratio of 1: 8-1: 10, and immediately and uniformly mixing to obtain anticoagulant whole blood; the anticoagulant is a 3.2%-3.8% sodium citrate aqueous solution or a composite anticoagulant containing sodium citrate and / or citric acid; s2, cold bath treatment; s3, transportation: transporting the anticoagulant whole blood in a heat preservation box at 2-8 DEG C; s4, standing is carried out; s5, siphon transfer: carrying out siphon transfer on the supernatant liquid; s6, centrifugation: performing graded centrifugation and collecting supernatant; and S7, preparation: taking the high-speed centrifugal supernatant, and adding at least one of Proclin300, potassium sorbate, sodium diacetate and benzalkonium bromide to obtain the traditional Chinese medicine composition. The animal plasma prepared through the technical scheme is free of hemolysis and insoluble particles, and the in-batch variation coefficient of CV: R, K, Angle and MA is smaller than 8%; and the inter-batch relative range: the inter-batch relative range of R, K, Angle and MA is less than 10%.

The invention discloses a wound disinfecting and repairing agent containing modified chitosan and a preparation method of the wound disinfecting and repairing agent, and belongs to the technical field of wound disinfecting and repairing agents, the composite wound disinfecting and repairing agent comprises the following components in percentage by mass: 3-10% of organic acid, 1-30% of chitosan, 2-20% of benzalkonium bromide, 1-10% of liposome solution and the balance of water; the preparation method of the wound disinfecting and repairing agent comprises the following steps: dissolving organic acid in water to obtain an acidic solution; adding chitosan into the acid solution, and stirring until the chitosan is completely homogenized; preparing a lipidosome solution in a manner of assisting lipidosome preparation by an electric field; mixing the liposome solution and the chitosan solution, adding benzalkonium bromide, and uniformly mixing; and separating out a chitosan solution with the molecular weight of more than 100,000 in the solution by using an ultrafiltration tube, and re-dissolving by using normal saline to obtain the chitosan solution. The efficiency of adsorbing bacteria by the chitosan can be greatly improved, so that the antibacterial ability is improved, and meanwhile, the inflammatory response can be quickly reduced and wound scabbing and repairing can be accelerated.

The invention relates to the technical field of medicines, and discloses a benzalkonium bromide synthesis process, which comprises: S1, blending bromododecane and water, and heating to a first temperature; s2, slowly adding dimethyl benzylamine, and heating to a second temperature; s3, after the reaction is finished, adding a crystallization solvent, stirring, crystallizing, centrifuging and drying to obtain a finished product. By adopting the synthesis process provided by the invention, the problems that the content of impurities in the product is high and the product is finally solid or colloid in the existing synthesis process of benzalkonium bromide can be solved. The benzalkonium bromide synthesized by the method has the advantages of stable product crystalline state and high purity.

The application relates to an evaluation method of demulsification performance of a cationic aromatic side chain demulsifier, which comprises the following steps: S1, synthesizing 4-bromobutyl triethylammonium bromide, 4-bromobutyl benzalkonium bromide and 4-bromobutyl quinoline bromide, and then synthesizing target products triethylamine-poly succinimide, N, N-dimethyl benzylamine-poly succinimide and quinoline-poly succinimide by chemical modification with poly succinimide as a main chain. The evaluation method of demulsification performance of the cationic aromatic side chain demulsifier, the synthesized TEA-PSI, BZK-PSI and QA-PSI demulsifiers can all be high-efficiency demulsification under different pH conditions, especially under acidic conditions (such as pH=2.0), the demulsification effect is particularly remarkable, and in actual application, the demulsification effect can be guaranteed even under harsh conditions, the demulsifier can not only effectively demulsify, but also can inhibit scale formation to a certain extent, so that the equipment corrosion is reduced, the service life of the equipment is prolonged, the production cost is reduced, the demulsifier has good biocompatibility and environmental friendliness.

The application discloses a sludge conditioner, which comprises the following components in parts by weight: benzalkonium bromide 0.5-1 parts, sodium hexametaphosphate 0.5-1 parts, titanium modified tanninized chitosan 5-10 parts and water 88-95 parts. The application also discloses application of the sludge conditioner in treatment of organic biochemical sludge. The efficient sludge conditioner is obtained by compounding benzalkonium bromide, sodium hexametaphosphate and titanium modified tanninized chitosan, the conditioner has the advantages of small dosage, excellent settling performance, no secondary pollution and low water content of treated sludge.