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312 results about "BENZALKONIUM BROMIDE" patented technology

Benzalkonium is a quaternary ammonium cationic surfactant that exhibits antimicrobial activity. Benzalkonium is clinically used as a disinfectant; it displays antibacterial activity by inducing dissociation of lipid membrane bilayer components and allowing cellular leakage.

Disinfection sterilizing type medical supersonic couplant and method of preparing the same

The invention discloses a disinfection sterilization medical ultrasonic coupling medium with the bactericidal function and used in the ultrasonic detection and treatment of skin and cavitary mucosa and a preparation method of the coupling medium, wherein, the ultrasonic coupling medium comprises propylene glycol, de-ionized water and one viscosity modifier of the hydroxy ethyl cellulose, carbomer and hydroxy propyl cellulose. The coupling medium further comprises a fungicide of 0.05 to 0.15 percent and the constituents of the fungicide are any one of polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, chlorhexidine acetate, trichlorobenzene phenoxy diphenyl ether and nanometer silver or any combination of the olyhexamethylene biguanide, the benzalkonium chloride, the benzalkonium bromide, the chlorhexidine acetate, the trichlorobenzene phenoxy diphenyl etherand, and the nanometer silver; the preparation method used for preparing the ultrasonic coupling medium is as follows: dispersing the hydroxy ethyl cellulose in the propylene glycol, stirring and dispersing the hydroxy ethyl cellulose by adding enough water, heating to 75 to 80 DEG C, preserving the heat for 30 minutes to cool the hydroxy ethyl cellulose and the propylene glycol to 45 DEG C, adding the fungicide to stir and cool the fungicide, the hydroxy ethyl cellulose and the propylene glycol to obtain the filled coupling medium. Tests show that the products of the coupling medium have fast and long sterilization effect and meet the requirements of various related standards.
Owner:广州市一杰医药科技有限公司

Chitosan contraceptive gel and preparation method thereof

The invention relates to a chitosan contraceptive gel and a preparation method thereof. The contraceptive gel consists of 0.5 to 1.5 percent of chitosan, 0.5 to 1.5 percent of carbomer, 0.5 to 3.0 percent of triethanolamine, 10 to 30 percent of ethanol, 5 to 20 percent of propylene glycol, 0.3 to 1.0 percent of benzalkonium chloride, 0.5 to 2.0 percent of glycerin, 0.5 to 2 percent of citric acid, 0.5 to 2 percent of polyethylene glycol 400, 0.3 to 1.0 percent of benzalkonium bromide, 0.1 to 0.5 percent of ethylparaben, 0.1 to 0.5 percent of methylparaben and the balance of purified water. The preparation method comprises the following steps of: spraying the chitosan and the carbomer on the liquid surface of the purified water, standing for a whole night to form a gel substrate, and removing bubbles under vacuum after standing; and then uniformly mixing the triethanolamine, the ethanol, the propylene glycol, the benzalkonium chloride, the glycerin, the citric acid, the polyethylene glycol, the benzalkonium bromide and the ethylparaben, and gradually adding into the gel substrate for uniformly mixing to prepare the chitosan contraceptive gel. The contraceptive gel is used in the vagina of a woman, has the effects of contraception, antibacterium and lubrication, avoids the influences on the vaginal pH, and maintains the normal balance of vaginal microflora; and the contraceptive gel also has the advantages of the antibacterium, inflection prevention, no damage to a genital mucosa, small irritation, low allergy and the like.
Owner:林一文 +1

Compound quaternary ammonium salt disinfection solution, and preparation method and application thereof

The invention discloses a quaternary ammonium salt disinfection solution, and a preparation method and application thereof. The quaternary ammonium salt disinfection solution comprises the following components: hexamethylenetetramine, benzalkonium bromide, benzalkonium chloride, polyhexamethylene guanidine, Tween 80, octadecyldimethylbenzyl chloride, isopropanol and sterile water. The invention further discloses a method for preparing the disinfection solution. According to the invention, hexamethylenetetramine, benzalkonium bromide, benzalkonium chloride, polyhexamethylene guanidine, octadecyldimethylbenzyl chloride and Tween 80 are combined together according to a specific mixing proportion, and the components have synergistic effects, so a variety of disadvantages of a single disinfectant variety or a simply-mixed disinfectant are overcome, and a variety of bacteria, fungi, spores and viruses can be thoroughly killed; meanwhile, the disinfection solution is safe to human body, is free of toxicity and stimulation, is convenient to use, can be directly used by being diluted with water, realizes one-step completion of disinfection and cleaning, has no corrosion to equipment and no harm on the environment, and is biodegradable.
Owner:GENERAL HOSPITAL OF CHINESE PEOPLES ARMED POLICEFORCES

Compound quaternary ammonium salt disinfectant liquid and preparation method thereof

InactiveCN101647469ASuitable for antibacterial disinfectionWide range of sterilizationBiocideAntiinfectivesAdditive ingredientDisinfectant
The invention relates to a compound quaternary ammonium salt disinfectant liquid, which is prepared by compounding single-double chain quaternary ammonium salt benzalkonium bromide and didodecyl dimethyl ammonium chloride used as raw components and povidone-iodine, dissolving the three components by using ethanol with the concentration of 95 percent as a solvent and mixing evenly. The compound quaternary ammonium salt disinfectant liquid comprises the following components by weight percent: 0.2-0.6 percent of benzalkonium bromide, 5-15 percent of didodecyl dimethyl ammonium chloride, 5-13 percent of povidone-iodine, 25-35 percent of ethanol with the concentration of 95 percent, and the balance of purified water. The implementation steps are as follows: (1), weighing benzalkonium bromide, didodecyl dimethyl ammonium chloride and povidone-iodine according to the proportion and placing into a container; (2), weighing the ethanol with the proportional concentration of 95 percent into the container; and (3) sufficiently and evenly mixing the components in the steps (1) and (2) to be dissolved, fixing volume by using purified water, separately packaging and checking according to the routine, and warehousing the qualified products. The invention has the advantages of simple preparation, safe use, no toxicity, no pollution for environment, stable medicine property and obvious effect.
Owner:天津市海纳德动物药业有限公司

Preparation technology of nanometer aluminum hydroxide adjuvant

The invention discloses a preparation technology of nanometer aluminum hydroxide adjuvant, comprising the following steps: taking benzalkonium bromide, n-caprylic alcohol and cyclohexane at equal ratio; stirring mixture at high speed, and pouring the mixture into a triangular flask; putting in a stir bar; putting the triangular flask on a magnetic stirrer, adding a proper quantity of AlCl3 solution, and stirring; slowing dropwise adding ammonia water into a separating funnel to regulate dripping rate; causing a reaction system to react for 2 hours at the pH of 10; after the reaction ends, adding acetone for demulsification and centrifugation; abandoning supernatant; respectively adding absolute ethyl alcohol and deionized water; evenly stirring by a glass rod; washing for three times, and decentralizing; collecting decentralized sediment into a beaker; drying for 12 hours in a drying oven to obtain fluffy Al(OH)3 adjuvant. The prepared nanometer aluminum hydroxide adjuvant has small grain diameter, good dispersibility and stability and favourable biocompatibility. In an animal experiment, the anti-tumor effect of nanometer aluminium adjuvant adsorption autovaccine is obviously superior to the curative effect obtained by using common aluminium adjuvant adsorption autovaccine.
Owner:SOUTHEAST UNIV

Disinfection sterilizing type medical supersonic couplant and method of preparing the same

The invention discloses a disinfection sterilization medical ultrasonic coupling medium with the bactericidal function and used in the ultrasonic detection and treatment of skin and cavitary mucosa and a preparation method of the coupling medium, wherein, the ultrasonic coupling medium comprises propylene glycol, de-ionized water and one viscosity modifier of the hydroxy ethyl cellulose, carbomerand hydroxy propyl cellulose. The coupling medium further comprises a fungicide of 0.05 to 0.15 percent and the constituents of the fungicide are any one of polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, chlorhexidine acetate, trichlorobenzene phenoxy diphenyl ether and nanometer silver or any combination of the olyhexamethylene biguanide, the benzalkonium chloride, thebenzalkonium bromide, the chlorhexidine acetate, the trichlorobenzene phenoxy diphenyl etherand, and the nanometer silver; the preparation method used for preparing the ultrasonic coupling medium is as follows: dispersing the hydroxy ethyl cellulose in the propylene glycol, stirring and dispersing the hydroxy ethyl cellulose by adding enough water, heating to 75 to 80 DEG C, preserving the heat for 30 minutes to cool the hydroxy ethyl cellulose and the propylene glycol to 45 DEG C, adding the fungicide to stir and cool the fungicide, the hydroxy ethyl cellulose and the propylene glycol to obtain the filled coupling medium. Tests show that the products of the coupling medium have fast and long sterilization effect and meet the requirements of various related standards.
Owner:广州市一杰医药科技有限公司

Infantile eczema nursing wet tissue

The invention discloses an infantile eczema nursing wet tissue and relates to the field of infantile eczema prevention nursing materials. The invention aims to solve the problem that traditional medicines for external application and medicines for oral administration cannot be conveniently used or have side effects. The infantile eczema nursing wet tissue comprises wet tissue liquid and a carrier of the wet tissue liquid, and is characterized in that the wet tissue liquid is prepared from the following raw material components in weight ratio: 0.05-0.1 percent of vitamin B, 0.05-0.1 percent of vitamin C, 0.05-0.1 percent of vitamin E, 0.2-0.4 percent of benzalkonium bromide, 0.05-0.1 percent of rehmannia extract, 0.05-0.1 percent of angelica sinensis extract, 1-2 percent of propylene glycol, 0.5-1 percent of aloe extract and the balance of water. The infantile eczema nursing wet tissue disclosed by the invention is simple and convenient in use and is suitable for preventing and nursing infantile eczema. Pure cotton non-woven fabric which is non-irritant to human bodies is used as the carrier, so that a solution for treating the eczema directly acts on an affected part. Nursing, cleaning and treatment are combined into a whole. On the basis of treating the eczema, itching-relieving traditional Chinese medicines are also added in the infantile eczema nursing wet tissue, thus, itching feelings brought to infants by the eczema can be effectively relieved. The vitamins capable of improving human immunity are also used, and thus, the eczema symptom can be effectively relieved.
Owner:TONGLING JIEYA BIOLOGIC TECH
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