9results about How to "No stimulation" patented technology

The invention relates to a preparation method of a cannabidiol nano-lipid carrier, in particular to a preparation method of a cannabidiol nano-lipid carrier with a transdermal absorption function. The invention aims to solve the problem that the existing cannabidiol lipid carrier cannot have high water solubility and high transdermal absorption function at the same time, and is poor in stability and easy to irritate skin. The method comprises the following steps: 1, weighing raw materials; 2, preparing an oil phase; 3, preparing a water phase; 4, mixing; 5, performing ultrasonic homogenization; 6, cooling; and 7, removing impurities. The preparation method is used for preparing the cannabidiol nano-lipid carrier with the transdermal absorption function.

The present application belongs to the technical field of medical hemostatic dressings and bandages, and particularly relates to a Duyuwei emergency hemostatic bandage, which comprises a bandage main body, the bandage main body is composed of a tight band and a dressing pad, the dressing pad is fixed to the front end of the tight band, the dressing pad is composed of an absorption area, a tablet area and a pad base layer, the absorption area and the tablet area are fixed on the pad base layer by traditional Chinese medicine glue, the absorption area is composed of Duyuwei gelatin sponge, the tablet area is composed of Duyuwei external-use tablets, and the pad base layer is composed of a medical degreasing cotton pad. A preparation method of the Duyuwei emergency hemostatic bandage comprises the following steps: Duyuwei medicinal material decoction piece component extraction, Duyuwei external-use tablet preparation, traditional Chinese medicine glue preparation, Duyuwei gelatin sponge preparation and Duyuwei hemostatic bandage preparation. The present application has the advantages of rapid hemostasis and remarkable efficacy: the Duyuwei extract, the gelatin sponge and the traditional Chinese medicine glue synergistically act to significantly shorten the hemostasis time. Animal experiments show that the average hemostasis time is short.

The invention relates to the technical field of nursing materials, and discloses eye washing liquid for relieving eye fatigue and a preparation method thereof.The eye washing liquid is prepared from trehalose, taurine, sodium gualenate, sodium hyaluronate, ergothioneine, vitamin B12, vitamin B6, xanthophyll, mint, a humectant, a bacteriostatic agent, a chelating agent, a pH regulator and deionized water. Through the synergistic effect of the first synergistic composition and the second synergistic composition, retina cell injury induced by blue light can be effectively repaired, the repairing effect is superior to that of simple addition of a single component, blue light oxidative injury is repaired through a multi-target synergistic mechanism, a three-layer structure of a tear film lipid layer, a water layer and a mucoprotein layer can be reconstructed, and the repairing effect is good. According to the present invention, the tearable film stability is significantly improved, the excellent protection and repair effect is provided, the compatibility of the components is good, the product stability is high, and the multiple effects of ocular surface cleaning, asthenopia relieving, conjunctival congestion reducing and blue light oxidation damage preventing are provided.

This invention relates to the field of silicone rubber materials technology, and discloses a high-transparency biocompatible material for endoscope-assisted water bags and its preparation method. The raw materials for this invention's high-transparency biocompatible material for endoscope-assisted water bags include 80-90 parts by weight of α,ω-dihydroxypolydimethylsiloxane, 10-20 parts by weight of silanol polylactic acid, and 0.04-0.07 parts by weight of catalyst, etc. This invention uses non-toxic and non-irritating silicone rubber and highly biocompatible polylactic acid as the matrix, which is non-irritating to the human body. The prepared material is suitable for use in medical devices such as endoscope-assisted water bags. The improved interfacial properties and compatibility between polylactic acid and α,ω-dihydroxypolydimethylsiloxane reduce the likelihood of interfacial defects, maintaining good light transmittance, tensile strength, and elongation at break. When used as an endoscope-assisted water bag, it allows for better observation, and polylactic acid imparts good biodegradability to the silicone rubber material.

The invention provides a preparation process of a novel medical acrylic pressure-sensitive adhesive, and relates to the field of medical acrylic pressure-sensitive adhesives. The preparation process of the novel medical acrylic pressure-sensitive adhesive comprises the following steps: S1, research on a synthesis process of the medical acrylic pressure-sensitive adhesive, S2, research on biocompatibility of the medical acrylic pressure-sensitive adhesive, and S3, research on a coating process of the medical pressure-sensitive adhesive and a proper adhesive coating amount: adopting butyl acrylate, acrylic acid-2-ethyl ethyl ester and methyl acrylate to prepare the novel medical acrylic pressure-sensitive adhesive. The medical pressure-sensitive adhesive which is used for transparent dressings, is good in viscosity, non-toxic and non-irritating, does not hurt the skin during stripping and has proper water vapor moisture permeability is developed, and the medical pressure-sensitive adhesive which is good in viscosity, non-toxic and non-irritating, does not hurt the skin during stripping and has proper water vapor moisture permeability is prepared by researching the formula proportion of the medical pressure-sensitive adhesive. And a medical pressure-sensitive adhesive having a suitable water vapor permeability.

The invention discloses an online pretreatment process for reducing the content of cell wall substances of tobacco stems, which comprises the following steps: (1) cleaned tobacco stems are added into high-pressure stem moistening equipment for steam explosion, and the steam explosion pressure is not greater than 2bar; (2) pressing and cutting the tobacco stems subjected to steam explosion to form cut stems; (3) adding a biological compound preparation into the cut stems for fermentation treatment; the biological compound preparation at least comprises cellulase, pectinase, laccase and ligninase. According to the method, the tobacco stems are subjected to steam explosion pretreatment under specific conditions, so that the structure of the tobacco stems is looser, meanwhile, the content of cell wall substances such as lignin is obviously reduced, the wood gas and irritation of the tobacco stems are reduced in combination with a specific fermentation process, and the cigarette product modified by adding the cut stems is free of irritation and offensive odor, smooth in smoke and high in smoking evaluation quality.

The invention discloses an automatic telescopic child stomach tube device capable of preventing abdominal distension and regurgitation under noninvasive ventilation. The device is used for preventing abdominal distension of a child patient under noninvasive ventilation. A nasal gastrointestinal tube head, a controller, an automatic breathing machine airflow blocker, a stomach tube body and a supporting strip form a whole, the automatic breathing machine airflow blocker is fixed to the upper middle portion of the stomach tube, in the process of using the stomach tube, medical workers place the stomach tube with the automatic breathing machine airflow blocker into the stomach through the esophagus of a child patient, and the stomach tube with the automatic breathing machine airflow blocker is fixed to the upper middle portion of the stomach tube. After the controller is pressed down, the airflow blocker of the automatic breathing machine fills the gap between the stomach tube and the esophagus, the situation that airflow enters the stomach through the esophagus to cause abdominal distension of a child patient in the application process of the non-invasive breathing machine is avoided, meanwhile, the influence of gastric regurgitation on the child patient is prevented, and therefore the situation that feeding of the child patient is affected by non-invasive ventilation is prevented.

This invention provides a transdermal follicular delivery system for active ingredients based on a protein carrier. The system comprises a composite structure of a small molecule active ingredient, a bioactive protein, and a polymer shell, with a size of 40-150 nm and a polymer shell thickness of 10-70 nm. The zeta potential of this protein carrier-based transdermal follicular delivery system is positively charged. The small molecule active ingredient is loaded within the bioactive protein, and the polymer shell coats the bioactive protein to form a protein nanogel. Both the small molecule active ingredient and the bioactive protein have beneficial effects on hair follicles. When this transdermal follicular delivery system is applied to the surface of a hair follicle or skin, the functional small molecules are delivered transdermally along with the nanogel to the interior of the hair follicle and surrounding tissues, where they are released in a controlled manner, thus effectively exerting their effects.

The invention relates to the technical field of food fresh keeping, and particularly discloses a composition with an antibacterial function, a preparation method and application in fresh keeping of hot fresh meat, the preparation method comprises the following steps: (S01) taking lactobacillus plantarum, lactobacillus reuteri and fructo-oligosaccharide, mixing, stirring, setting constant temperature, and adjusting humidity to obtain an antibacterial matrix; (S02) mixing sodium alginate with the bacteriostatic substrate, stirring, and adjusting the pH value to obtain a bacteriostatic structure substrate; (S03) adding a grape seed extract, adjusting the stirring speed and duration, measuring the concentration data of each component, and testing the solubility to obtain a functional antibacterial component; and (S04) adopting principal component analysis, gradually adjusting the proportion of each component, judging the influence of different proportions on bacterial colony inhibition by monitoring and analyzing the number of bacterial colonies and the inhibition rate, and obtaining an optimal proportion combination according to experimental data to obtain a preparation scheme of the composition with the antibacterial function. The invention has the characteristics of being beneficial to maintaining the health and balance of intestinal microecology, good in safety and better in stability.