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26results about How to "Non-irritating" patented technology

Composition with anti-aging effect as well as preparation method and application thereof

The invention discloses a composition with an anti-aging effect and a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition is prepared by compounding a traditional Chinese medicine active component, a moisturizing and permeation promoting component and a repairing and anti-aging auxiliary component, and the traditional Chinese medicine active component is composed of three zymolytes and three fermentation extracts which are respectively prepared from six medicinal and edible traditional Chinese medicine raw materials through differentiated composite enzymolysis and probiotic anaerobic fermentation processes. The problems that traditional Chinese medicine extracts are low in transdermal absorption rate, poor in bioavailability and insufficient in cosmetic system stability are solved, active ingredients are small-molecularized through process optimization, a multi-target synergistic anti-aging system is formed by matching with functional components, the anti-aging and repairing composition has excellent anti-aging and repairing effects, physical and chemical stability and skin safety, and the anti-aging and repairing composition has a good application prospect. The composition is suitable for various skin types and can be widely applied to preparation of anti-aging repair cosmetics.
Owner:SHANGHAI JIAYU BIOLOGICAL TECH CO LTD +1

An infant and child repairing essence water containing a fermented trituberculina active ingredient

The present application discloses a kind of infant repair essence water containing fermented triple snail active ingredients, belong to the technical field of cosmetic biological formula.The product is composed of the following mass percent raw materials: snail mucus freeze-dried powder 0.1-2.0%, fermented small molecule snail peptide 0.2-3.0%, fermented active snail enzyme 0.05-1.0%, supplemented with glycerol, panthenol, sodium hyaluronate, dipotassium glycyrrhizinate and mild preservative system, the balance is purified water.Innovation adopts biological deep fermentation modification technology, molecular optimization and desensitization purification are carried out on snail peptide and snail enzyme, combined with low-temperature vacuum freeze-dried snail mucus freeze-dried powder, to construct a three-dimensional synergistic repair system of surface layer water-locking-middle layer anti-inflammatory-muscle basement regeneration.The product is free of perfume, alcohol, hormone and sensitizing preservative, suitable for 0-12 years old infant fragile muscle, can be widely used in daily skin care, barrier repair, eczema itching and redness emergency scene.
Owner:NANJING SNAIL ERA BIOTECHNOLOGY CO LTD

A heating non-combustible cigarette cooling unit containing phase change cooling material and heating non-combustible cigarette

ActiveCN117179372BHigh latent heat of phase changeLow thermal hysteresisCigar manufactureThermodynamicsPolyethylene glycol
This invention discloses a heating-not-burning cigarette cooling unit containing a phase change cooling material and a heating-not-burning cigarette. The unit comprises at least a carrier paper and a phase change cooling material coated on the carrier paper. The phase change cooling material is distributed in a non-fully-covering, regular pattern on the carrier paper. The carrier paper coated with the phase change cooling material forms multiple longitudinally extending channels through winding, folding, gathering, bending, and wrinkling, and has a porosity of 40%-90% along the longitudinal direction. The phase change cooling material comprises 55-96 parts by weight of polyethylene glycol, 1-5 parts by weight of in-situ reinforcing material, and 3-40 parts by weight of thermally conductive filler. The heating-not-burning cigarette cooling unit of this invention has the advantages of high latent heat of phase change, low thermal hysteresis effect, high heat absorption efficiency, apparent stability without collapse, and no leakage.
Owner:HUAQIAO UNIVERSITY

A simulated hand device for psychological comfort

This utility model relates to the field of medical comfort technology, specifically disclosing a simulated hand device for psychological comfort, including a comfort component one and a comfort component two. The comfort component one and the comfort component two are respectively fitted onto the palm area and back surface of the patient's hand, forming a symmetrical wrapping structure. A temperature control mechanism is embedded in the internal space of the comfort component one and the comfort component two. Precise temperature control: Temperature is controllable through an electric heating wire or PTC heating element to meet the personalized temperature needs of different patients. Modular design: The outer contact layer and inner sealing layer are detachable, facilitating cleaning, disinfection, and component replacement, improving hygiene. Flexible adaptability: The Velcro connecting strap and pleated structure can adapt to different hand shapes, enhancing wearing comfort. Acupoint-assisted therapy: Marked points accurately locate the Shenmen and Neiguan acupoints, enhancing the therapeutic effect of psychological comfort. Material safety: Medical-grade silicone material is non-irritating, and the textured layer simulates the feel of skin, reducing the risk of allergies.
Owner:THE SECOND AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV

A heating non-combustion cigarette cooling unit and a heating non-combustion cigarette

ActiveCN117179373BHigh latent heat of phase changeLow thermal hysteresisCigar manufactureMetal foilTobacco product
This invention discloses a heated tobacco cooling unit with enhanced thermal conductivity and a heated tobacco product, comprising a carrier sheet, several metal foils, and several phase change cooling materials. The carrier sheet has several perforated holes. Several metal foils are disposed on at least one side of the carrier sheet and cover the perforated holes. The metal foils are spaced apart and discretely arranged. The phase change cooling materials are filled within the perforated holes using the metal foils as a carrier. The carrier sheet containing the metal foils and phase change cooling materials is formed into the heated tobacco cooling unit by at least one of the following methods: winding, folding, gathering, bending, and pleating. The metal foils are regularly and intermittently distributed along the longitudinal direction of the tobacco strip. The cooling unit has multiple longitudinally extending channels, and the porosity of the cross-section is 40%-90%. The heated tobacco cooling unit with enhanced thermal conductivity of this invention has the advantages of high latent heat of phase change, low thermal hysteresis effect, high heat absorption efficiency, apparent stability without collapse, and no leakage.
Owner:HUAQIAO UNIVERSITY

A silk fiber-based anti-decubitus decompression pad and a preparation method thereof

ActiveCN118105260Bgood biocompatibilityNon-irritating
The application discloses a silk fiber-based anti-bedsores decompression pad and a preparation method thereof, which comprises a fabric layer in a concave shape, an aerogel layer and a fiber layer are arranged in the fabric layer from bottom to top, the total height of the aerogel layer and the fiber layer after being stacked is equal to the depth of the fabric layer, the fiber layer is prepared from drug-loaded hydrophobically modified sodium alginate fiber, and the aerogel layer is prepared from degummed silk-sodium alginate composite aerogel with a three-dimensional porous structure. The decompression pad has antibacterial and healing promotion effects, the silk fiber enhances the physical and mechanical properties of the aerogel layer, can greatly reduce external pressure, has excellent air permeation effect due to the through-hole structure in the interior, can fully and quickly absorb wound exudates, the sodium alginate-based material also provides a suitable microenvironment for cell growth, accelerates wound healing, and is suitable for the prevention and treatment of bedsores of patients who need to be in bed for a long time.
Owner:JIANGNAN UNIV

A high-toughness stretchable positive electrode material with TPU / ANF / inorganic nanoparticle composite and a preparation method thereof

PendingCN122587455AMeet the deformation effectMeet the requirements
The application relates to the technical field of high-molecular fiber sensing, in particular to a high-toughness TPU / ANF / inorganic nanoparticle composite nanometer friction positive electrode material and a preparation method thereof. The preparation method takes TPU as a base main material, does not depend on a chemical cross-linking method, and realizes flexible adaptation of a complex deformation scene by virtue of excellent stretchable deformation performance and flexible characteristics of the TPU. Meanwhile, aramid nanofiber (ANF) is introduced as a reinforcing phase, the high-strength and high-modulus characteristics of the aramid nanofiber are utilized to improve the stress and strain capacity and mechanical stability of the base, the aramid nanofiber can lock the molecular structure in the TPU, and the aramid nanofiber can inhibit significant shrinkage of the material when the temperature is increased, so that the aramid nanofiber has the dual functions of mechanical enhancement and size stability, and the reliability of a generator is ensured.
Owner:SHAANXI UNIV OF SCI & TECH

A high-transparency biocompatible material for endoscopic-assisted water bags and its preparation method

PendingCN122563346ANo stimulationNon-irritating
This invention relates to the field of silicone rubber materials technology, and discloses a high-transparency biocompatible material for endoscope-assisted water bags and its preparation method. The raw materials for this invention's high-transparency biocompatible material for endoscope-assisted water bags include 80-90 parts by weight of α,ω-dihydroxypolydimethylsiloxane, 10-20 parts by weight of silanol polylactic acid, and 0.04-0.07 parts by weight of catalyst, etc. This invention uses non-toxic and non-irritating silicone rubber and highly biocompatible polylactic acid as the matrix, which is non-irritating to the human body. The prepared material is suitable for use in medical devices such as endoscope-assisted water bags. The improved interfacial properties and compatibility between polylactic acid and α,ω-dihydroxypolydimethylsiloxane reduce the likelihood of interfacial defects, maintaining good light transmittance, tensile strength, and elongation at break. When used as an endoscope-assisted water bag, it allows for better observation, and polylactic acid imparts good biodegradability to the silicone rubber material.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)

Processing method of traditional Chinese medicine pinellia ternate

ActiveCN118203626Bavoid poisoningsafe and effectiveBiotechnologyNervous system
This invention discloses a method for processing the traditional Chinese medicine Pinellia ternata. The method involves processing the raw Pinellia ternata in a phosphate solution under sealed conditions, followed by slicing into thick pieces and drying to obtain the processed product. The medicinal material is Pinellia ternata or Arisaema heterophyllum. The method of this invention uses phosphate solution to soak Pinellia ternata, which significantly reduces its irritant properties. Toxicological experiments have shown that the processed Pinellia ternata is non-irritating and does not cause a numbing sensation on the tongue. This invention does not use alum, thus avoiding the use of residual Al from alum as a processing excipient in pharmacopoeia methods. 3+ The toxicity to the human nervous system is minimal, ensuring safe and effective clinical use. Compared with traditional processing methods, phosphate-processed Pinellia ternata has the advantages of quantifiable process indicators, simple operation, and no introduction of hazards. It provides a reference for the processing technology of phosphate-processed Pinellia ternata, lays the foundation for the quality stability of phosphate-processed Pinellia ternata, and ensures the safety and efficacy of traditional Chinese medicine.
Owner:CHINA PHARM UNIV

A plant-decomposable deodorant formulation and a configuration method thereof

PendingCN122499340Aachieve captureachieve decomposition
The present application belongs to the technical field of material chemistry and environmental governance, and discloses a plant decomposition type deodorant formula and a configuration method. In view of the defects of the existing deodorization technology, such as secondary pollution, slow effect, only masking odor, insufficient product stability and the like, the present application uses tea polyphenol extract, yucca extract, grape seed extract, various plant essential oils and other pure natural plant extracts as raw materials, does not contain chemical synthetic additives, and is prepared through a standardized process of precise control of constant temperature environment, grading stirring speed, step-by-step feeding and reaction time. The deodorant can target decomposition of various foul-smelling molecules, has the effects of bacteriostasis and oxidation resistance, is completely deodorized, has strong product stability, is safe and non-irritating, has no secondary pollution, and can be widely applied to foul odor treatment in multiple scenes such as livestock breeding, garbage treatment, sewage treatment, public environment and the like.
Owner:GUANGDONG HANKE ECOLOGICAL TECHNOLOGY CO LTD

Application of tetramethylcurcumin in whitening

The application belongs to the technical field of cosmetics, and discloses application of tetramethylcurcumin in whitening. The application first discovers that tetramethylcurcumin has the effect of whitening, specifically, can inhibit melanin production and tyrosinase activity, and the inhibiting effect is strong, and tetramethylcurcumin has no irritation to red blood cells, indicating that tetramethylcurcumin has certain safety as a potential raw material component of cosmetics.
Owner:GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD

Skin freckle-removing and whitening composite film spraying agent and preparation method thereof

PendingCN121818430ANon-irritatingStrong drug penetration abilityCosmetic preparationsToilet preparationsPropanediolSodium hyaluronate
The invention discloses a preparation method of a skin freckle-removing and whitening composite film spraying agent, which comprises the following steps: S1, preparing a sodium alginate solution with the content of sodium alginate being 1-1.5%; s2, sodium hyaluronate, whitening components, propylene glycol and azone are added into the sodium alginate solution to be dissolved, the mass ratio of sodium alginate to sodium hyaluronate to propylene glycol to azone is 1: (0.5-1): (0.5-1): 1, and a compound film forming solution is obtained; and S3, uniformly spreading the compound film-forming solution prepared in the step S2 in a vessel, uniformly spraying the uniform cross-linking solution in the vessel, and after a layer of film is formed, taking out the film to obtain the freckle-removing and whitening type composite film spraying agent for the skin. The prepared skin freckle-removing and whitening composite film spraying agent has the effects of no irritation to skin, strong medicine infiltration capacity, high mechanical strength, moisture retention and oil control.
Owner:HANGZHOU YOUDU BIOTECHNOLOGY CO LTD

Cooling sunscreen cream as well as preparation method and application thereof

The invention discloses a cooling sunscreen cream as well as a preparation method and application thereof. The cooling sunscreen cream comprises sunscreen radiation refrigeration particles, a chemical cooling component, a physical cooling component and a mosquito repelling component. The sunscreen cream disclosed by the invention contains efficient cold-feeling active ingredients and can generate obvious cool feeling within 8-15 seconds after being smeared, the average strength reaches 3.7 / 5 minutes, the cold feeling duration is 25-40 minutes, the skin surface temperature is effectively reduced, and the comfortable experience is improved; the sunscreen index is up to 64, and meanwhile, the sunscreen cream has multiple skin care functions of moisturizing, relieving, protecting, refreshing, repelling mosquitoes and the like.
Owner:TSINGHUA UNIVERSITY

Metal cutting oil, its preparation method and application

This invention provides a metal cutting oil, its preparation method, and its application. The metal cutting oil comprises the following components by mass percentage: 10-15% oiliness agent, 3-5% extreme pressure agent, 0.5-1% antioxidant, and the balance being base oil; wherein the oiliness agent is composed of a base oil with a viscosity of 30-450 mmHg. 2 / s high viscosity oily agent with viscosity of 5-15mm 2 The low-viscosity oily agent is composed of a mass ratio of 5:(1-7). The cutting oil provided by this invention has good extreme pressure lubrication performance and high and low temperature stability, and can prevent phenomena such as tool sticking and welding during aluminum alloy cutting. It is suitable for cutting aluminum alloys.
Owner:JIHUA LAB

A clear stable low-irritation plant composite beverage and its preparation method and application

PendingCN122074606Astable complex structurenon-irritatingFood scienceBiotechnologyPolyphenol
This invention discloses a clear, stable, and low-irritant plant-based compound beverage, its preparation method, and its application. The beverage is formed by the in-situ self-assembly of polyphenol-containing plant extracts and small-molecule food-derived oligopeptides in an aqueous solution, creating nano-complex particles with an average particle size of 80–200 nm, a Zeta potential of -25 to -40 mV, and a PDI ≤ 0.3. It contains no added exogenous stabilizers, thickeners, flavoring agents, fragrances, or colorings. After 30 days of accelerated clarification at 37°C, no precipitation occurs, with a turbidity ≤ 5 NTU and a light transmittance ≥ 90%, effectively masking bitter and spicy irritations. The plant extracts are a compound of kudzu root, Japanese raisin tree fruit, chrysanthemum, poria cocos, monk fruit, ginger, and yam, with a polyphenol to oligopeptide mass ratio of 3:4. The product can relieve dry mouth and throat discomfort caused by alcohol consumption, staying up late, and smoking. The process is simple and suitable for industrial production.
Owner:康一杰

Traditional Chinese medicine health-care comb and preparation method thereof

PendingCN121944066ABalance multiple health effectsCompatibility reservedMassage combsAntibacterial agentsMedicinal herbsNursing care
The invention belongs to the technical field of traditional Chinese medicine nursing, and discloses a traditional Chinese medicine health-care comb and a preparation method thereof.The traditional Chinese medicine health-care comb is prepared through the steps that traditional Chinese medicine powder, nanmu sticky powder, a nanometer whisker reinforcing agent and composite antibacterial factors are subjected to dry mixing and then mixed with a traditional Chinese medicine extracting solution according to the mass ratio of 1: 1, and compression molding is conducted; the mass ratio of the traditional Chinese medicine powder to the nanmu sticky powder to the nano whisker reinforcing agent to the composite antibacterial factor is (65-70): (20-25): (5-8): (2-3); through a double-effect fusion mode of the medicine powder and the extracting solution, combination of physical massage and medicine effect permeation is achieved, compatibility of multiple medicinal materials is achieved, the traditional Chinese medicine theory and scalp care requirements are considered, and multiple health-care effects of nourishing blood and blacking hair, growing hair and preventing hair loss, promoting blood circulation to remove meridian obstruction and balancing the scalp environment are achieved; meanwhile, a nano whisker reinforcing agent and a composite antibacterial factor are also added, so that the problems that the traditional Chinese medicine health-care comb is easy to break and mildew and short in service life in life and use are solved.
Owner:AGE OF INNOCENCE BIOTECHNOLOGY (GUANGZHOU) CO LTD

A hollow metal tube filled with phase change cooling material for heated non-combustible cigarettes and heated non-combustible cigarettes.

ActiveCN117297172BHigh latent heat of phase changeLow thermal hysteresisCigar manufactureComposite materialSmoke
This invention discloses a hollow metal tube filled with phase change cooling material for heated non-combustible cigarettes, and the heated non-combustible cigarette itself. The heating non-combustible cigarette includes a hollow metal tube and a phase change cooling material. The phase change cooling material is filled and sealed inside the hollow metal tube. The hollow metal tube filled with the phase change cooling material is placed inside the heated non-combustible cigarette in at least one of the following ways: winding, folding, gathering, or bending, to form a cooling unit. The cooling unit has a longitudinally extending smoke channel; the longitudinal direction of the cooling unit has a porosity of 40%-90%. The hollow metal tube filled with phase change cooling material cooling unit of this invention has the advantages of high latent heat of phase change, low thermal hysteresis effect, high heat absorption efficiency, apparent stability without collapse, and no leakage.
Owner:HUAQIAO UNIVERSITY

A bactericidal disinfectant gel and a method of making the same

This invention provides a bactericidal and disinfectant gel and its preparation method, composed of plant-based active ingredients and excipients. The plant-based active ingredients consist of alkaloids, flavonoids, polyphenols, and polysaccharides. This invention, through the scientific formulation of flavonoids, alkaloids, polyphenols, and polysaccharides, not only achieves highly effective killing of common pathogens causing fungal skin diseases, but also possesses anti-inflammatory, antioxidant, and tissue repair-promoting functions, solving the technical problem of limited efficacy in existing fungal skin disease products.
Owner:CHONGQING XINLINGFANG BIOPHARMACEUTICAL CO LTD

High-activity eggshell membrane composite enzymatic hydrolysis extraction process and extract

The invention belongs to but not limited to the technical field of biological extraction, and discloses a high-activity eggshell membrane composite enzymatic hydrolysis extraction process and an extract, the process adopts a composite enzyme system of alkaline protease and papain for directional hydrolysis, and is combined with low-temperature ultrafiltration purification and freeze drying technologies, the total amount of amino acid in the obtained extract is greater than or equal to 79g / 100g, and the total amount of amino acid in the extract is greater than or equal to 79g / 100g. The sodium hyaluronate content is greater than or equal to 4.4 g / 100g, the collagen content is greater than or equal to 6.8%, the water solubility is greater than or equal to 95%, no skin and eye irritation is caused, the method can be widely applied to the fields of food health care, cosmetics, pet food and the like, the technical problems of loss of active ingredients and poor water solubility of a traditional process are solved, and the method is stable and controllable and suitable for industrial production. Through detection, the total amount of amino acid in the extract reaches 79.3 g / 100g, the content of sodium hyaluronate is 4.4 g / 100g, the content of collagen is 6.8%, and the extract is free of skin and eye irritation, can meet the application requirements in the fields of food health care, cosmetics and the like, is mature and controllable in process and is suitable for industrial large-scale production.
Owner:吉林生奥生物科技有限公司

A traditional Chinese medicine compound preparation with tranquilizing effect on cattle, and a preparation method and application thereof

The application provides a traditional Chinese medicine compound preparation with a calming effect on cattle, a preparation method and application thereof, and relates to the technical field of traditional Chinese veterinary medicine. The traditional Chinese medicine compound preparation takes Litsea chenii, Spondias axillaris, Polygala, gold button, safflower, mace, clove as core raw materials, is supplemented with bright blue aluminum lake as an indicator, and is prepared by matching a dissolving agent, a thickening agent and deionized water. The traditional Chinese medicine compound preparation has a significant calming effect, and can play a targeted role on different cattle: for new cows, the milk yield can be effectively improved, and the incidence of postpartum diseases can be reduced; for bulls, the number of fighting behaviors can be significantly reduced, and the risk of injury can be reduced; for calves, the weaning stress response can be relieved, the number of weaning period bellowing can be reduced, and the incidence of diarrhea can be reduced. The traditional Chinese medicine compound preparation has the advantages of safety, high efficiency, convenient operation, no skin residue and the like, relies on visual marking to assist in drug administration management, provides a new solution for healthy breeding of large-scale cattle farms, and has a significant application value.
Owner:HENAN YUANYUTANG DRUG RES & DEV CO LTD +2

Fire blanket for extinguishing new energy battery fire

PendingCN122499451ASolve deflagrationsolver explosion
This invention discloses a fire control blanket for extinguishing fires in new energy batteries. The fire control blanket is characterized by being composed of a layer of high-silica glass fiber cloth and a layer of high-oxygen-index pre-oxidized fiber cloth. The high-silica glass fiber cloth has a silica weight content ≥96%, and the pre-oxidized fiber cloth has an oxygen index greater than 45%. The fire control blanket provides breathability through the composite structure of the high-silica glass fiber cloth and the pre-oxidized fiber cloth to release flammable gases generated by battery fires, and filters burning particles when covering open flames. It fully utilizes the heat insulation, non-combustibility, high-temperature resistance, ease of use, and breathability of the high-silica glass fiber cloth and the high-oxygen-index fiber cloth. This can solve the problem of deflagration or explosion caused by the accumulation of large amounts of flammable gases released from new energy battery fires, and can filter out burning particles to purify the air, reduce the adsorption of harmful particles, and achieve the advantages of being environmentally friendly and non-toxic.
Owner:ANHUI JIELIANG NEW MATERIALS CO LTD

A composition with anti-aging efficacy and its preparation method and application

ActiveCN121943768BFast penetrationImprove wrinkles
The application discloses a composition with anti-aging efficacy and a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition is compounded by a traditional Chinese medicine active component, a moisturizing and penetration promoting component and a repair and anti-aging auxiliary component, wherein the traditional Chinese medicine active component is composed of three kinds of enzymolysis products and three kinds of fermentation extracts prepared respectively by differential complex enzymolysis and probiotic anaerobic fermentation process of six kinds of medicinal and edible traditional Chinese medicine raw materials. The application solves the pain points of low transdermal absorption rate, poor bioavailability and insufficient stability of the traditional Chinese medicine extract in the cosmetic system, realizes the small molecule of the active ingredient through process optimization, forms a multi-target point synergistic anti-aging system by matching the functional components, has excellent anti-aging repair efficacy, physical and chemical stability and skin safety, is suitable for various skin qualities, and can be widely applied to the preparation of anti-aging and repair cosmetics.
Owner:SHANGHAI JIAYU BIOLOGICAL TECH CO LTD +1

Sodium hyaluronate wound care spray containing composite metal elements as well as preparation method and application of sodium hyaluronate wound care spray

The invention discloses a sodium hyaluronate wound care spray containing composite metal elements as well as a preparation method and application thereof, and belongs to the technical field of wound care. The nursing spray comprises the following components in percentage by mass: 0.1%-1% of sodium hyaluronate, 0.1%-1% of total metal elements, 0.5%-1.5% of a humectant and the balance of normal saline, the metal elements are composed of an iron element, a zinc element and a magnesium element, and the mass ratio of the iron element to the zinc element to the magnesium element is (1-2): (0.5-0.7): (1-1.8). The nursing spray prepared through component synergism has moisturizing, protecting and wound healing assisting functions, is wide in spray form adaptability and convenient to use, has the effect superior to that of commercially available products, and is suitable for superficial and mucous membrane wound nursing.
Owner:SHENGTING HOLDINGS DEVELOPMENT CO LTD

Bupivacaine meloxicam sustained release solution based on ethyl cellulose and its preparation method and application

PendingCN122499103ASlow down the process of proliferationMeet the actual demand for long-lasting postoperative analgesia
The application relates to the technical field of pharmaceutical preparations, in particular to a bupivacaine meloxicam sustained-release solution based on ethyl cellulose as well as a preparation method and application thereof. The sustained-release solution comprises 2-3 parts of bupivacaine or a pharmaceutically acceptable salt thereof, 0.05-0.1 parts of meloxicam or a pharmaceutically acceptable salt thereof, 5-20 parts of ethyl cellulose, 20-45 parts of glyceryl triacetate, 30-45 parts of dimethyl sulfoxide, 0.03-0.07 parts of maleic acid and 0.03-0.07 parts of dibutylhydroxytoluene. The application takes ethyl cellulose as a core sustained-release carrier, combines a specific solvent system, and forms a uniform and stable sustained-release solution. The preparation can continuously release drugs for more than 72 hours after use, is effectively used for postoperative long-acting analgesia, and has the outstanding advantages of good biocompatibility, simple preparation process, low risk of free implementation and the like.
Owner:GANNAN INST OF INNOVATION & TRANSLATIONAL MEDICINE

A method for preparing mulberry leaf extract through multiple fermentation, and the mulberry leaf extract and its applications.

ActiveCN120859902Bfully convertedfull synergyCosmetic preparationsToilet preparationsBiotechnologyYerba santa extract
This invention relates to a method for preparing mulberry leaf extract through multiple fermentation, and the mulberry leaf extract and its applications, belonging to the field of cosmetic raw material extraction technology. This method, through a complex enzymatic pretreatment, three-stage specific fermentation, and ultrafiltration purification process, produces a mulberry leaf extract that is non-irritating to the skin, exhibits good safety, high bioavailability, and excellent skin penetration, demonstrating significant effects in enhancing the skin barrier, moisturizing, and reducing wrinkles.
Owner:GUANGDONG HUASANG LIXI BIOTECHNOLOGY CO LTD