184results about How to "Inhibit synthesis" patented technology

The invention relates to the technical field of microorganisms, in particular to application of pediococcus acidilactici ZJUIDS13 in improvement of liver diseases, including improvement of alcoholic liver diseases and improvement of fatty liver diseases related to metabolic dysfunction. The pediococcus acidilactici ZJUIDS13 has relatively strong capability of protecting liver injury induced by alcohol, and can improve the states of liver injury and lipid metabolism disorder caused by high fat diet.

The invention relates to a skin care composition containing white truffle and plant exosome and application thereof. The skin care composition containing white truffle and plant exosome comprises white truffle extract, chlorella exosome, DNA sodium, superoxide dismutase and fermentation product filtrate, the fermentation product filtrate comprises any one or a combination of at least two of lactobacillus / soybean milk fermentation product filtrate, lactobacillus / mung bean seed extract / sodium glutamate fermentation product filtrate, bifidobacterium fermentation product filtrate or saccharomycetes / rice fermentation product filtrate. According to the invention, the white truffle extract, the chlorella exosome, the DNA sodium, the superoxide dismutase and the fermentation product filtrate are creatively combined, and the composition has unexpected synergistic interaction in the aspects of inhibiting melanin synthesis, accelerating melanin metabolism and resisting oxidation and aging. The composition is mild in performance and free of irritation and toxic and side effects, and can be applied to cosmetic products more safely.

The invention discloses a whitening nano-emulsion and a preparation method thereof, and relates to the technical field of cosmetics and skin care products. The whitening nano-emulsion is prepared from the following components in percentage by weight: 2.0 to 10.0 percent of an emulsifying agent, 4.0 to 10.0 percent of an emollient, 3.0 to 8.0 percent of glycerol, 3.0 to 8.0 percent of butanediol, 0.5 to 3.0 percent of nicotinamide, 1.0 to 3.0 percent of a Soulixian extract, 0.5 to 3.0 percent of ascorbyl tetraisopalmitate, 0.3 to 3.0 percent of hydrogenated lecithin, 0.1 to 2.0 percent of hydroxyethyl piperazine ethanesulfonic acid, 0.1 to 1.0 percent of SymSitive1609, 0.03 to 0.5 percent of a mulberry root extract, 0.03 to 1.0 percent of cerium oxide and the balance of water. The toothpaste is prepared from the following components in percentage by weight: 0.05 to 0.5 percent of tocopheryl acetate, 0.03 to 0.3 percent of stearyl glycyrrhetinic acid ester, 0.01 to 0.1 percent of poly gamma-sodium glutamate, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.2 to 1.0 percent of preservative, 0.01 to 0.1 percent of aromatic and the balance of water, wherein the total The prepared whitening nano-emulsion can solve the problems of excessive addition, difficult absorption and instability of active ingredients of cosmetics, can inhibit DPPH free radical activity, hydroxyl free radical activity and tyrosinase activity through the synergistic effect of all the components, achieves the effects of resisting oxidation, whitening, removing freckles, brightening skin and the like, and does not cause damage to the skin.

The invention belongs to the technical field of bioengineering, and particularly relates to application of plant hormones in inhibition of fungal growth and inhibition of mycotoxin synthesis. The invention provides an application of a plant hormone in inhibition of fungal growth and inhibition of synthesis of mycotoxin, the plant hormone is methyl jasmonate, the mycotoxin is deoxynivalenol, and the final concentration of the methyl jasmonate is 30-4000 [mu] M. The invention provides an inhibitor for fusarium graminearum growth and DON synthesis, and provides a botanical inhibitor for formulating a safe, pollution-free and green wheat scab prevention and control strategy.

The invention discloses selenium-containing unsaturated polyesteramide and a preparation method thereof, and the preparation method comprises the following steps: mixing and dissolving a diamine compound, propiolic acid ester and selenolactone in an organic solvent, and carrying out chemical reaction to obtain the selenium-containing unsaturated polyesteramide. A diamine compound, propiolic acid ester and selenolactone are used as raw materials, selenium-containing unsaturated polyesteramide is generated through click polymerization reaction of selenol and alkyne, the novel preparation method of selenium-containing unsaturated polyesteramide is developed, and the prepared polyesteramide is narrow in molecular weight distribution, controllable in structure and adjustable in degradation rate, and can be used for preparing selenium-containing unsaturated polyesteramide. Long-term stability is good, multiple responsiveness is achieved, and optical performance is good; the raw materials are wide in source, tedious substrate synthesis is avoided, the steps are simple, the reaction conditions are mild, the polymerization speed is high, and efficient large-scale production can be achieved; no catalyst is needed, no by-product is generated, and extra purification is not needed.

The invention relates to application of VBIT-4 or pharmaceutically acceptable salt thereof in preparation of drugs for preventing or treating vitiligo and complications thereof. A large number of modern pharmacological scientific researches and in-vivo pharmacodynamic tests prove that VBIT-4 has a treatment effect on a leucoderma mouse model and inhibits synthesis of inflammatory factors and chemotactic factors in a leucoderma mouse skin lesion area. The mechanism of the invention is that VBIT-4 inhibits the expression of inflammatory factors and chemotactic factors in skin tissues so as to treat leucoderma, compared with the existing treatment means, VBIT-4 can promote the compound color of pigments in a skin lesion region on the back of a leucoderma mouse, has no obvious toxicity, and reduces the expression level of inflammatory factors (IL-1beta, IL-6 and IFN-alpha) and chemotactic factors (CXCL9 and CXCL10). In conclusion, the VBIT-4 is clear in action mechanism, remarkable in effect and free of obvious side effects, and has remarkable advantages and progress compared with existing drugs.

The invention relates to a skin care composition containing perigord truffle and plant exosome and application of the skin care composition. The skin care composition containing perigord truffle and plant exosome comprises perigord truffle extract, chlorella exosome, malachite extract, fermentation product filtrate and soluble collagen. The fermentation product filtrate comprises any one or a combination of at least two of a Thermus thermophilus fermentation product, a lactobacillus / soybean milk fermentation product filtrate or a lactobacillus / mung bean seed extract / sodium glutamate fermentation product filtrate. The perigord truffle extract, the chlorella exosome, the malachite extract, the fermentation product filtrate and the soluble collagen are creatively combined to form the composition with the whitening, anti-allergy and anti-oxidation effects, and the composition has the effects of inhibiting melanin synthesis, relieving skin inflammation response, whitening skin, resisting allergy and resisting oxidation. And an unexpected synergistic effect is achieved in the aspects of oxidation resistance and aging resistance. The composition is mild in performance and free of irritation and toxic and side effects, and can be applied to cosmetic products more safely.

The invention belongs to the technical field of gene engineering, and provides a gene OsMYB1 and application thereof in negative regulation of anthocyanin synthesis. The cDNA (complementary deoxyribonucleic acid) sequence of the gene OsMYB1 is as shown in SEQ ID NO. 1. A systematic molecular biology experiment proves that the OsMYB1 inhibits the expression of the OsDFR by combining with a promoter region of an anthocyanin synthesis key structural gene OsDFR, so that the synthesis of anthocyanin is inhibited. Meanwhile, the OsMYB1 can form an MBW ternary complex with the OsB2 and the OsPAC1 to competitively inhibit the synthesis of the anthocyanin, which indicates that the transcription factor OsMYB1 is a negative regulation factor for the synthesis of the rice anthocyanin, the content of the rice anthocyanin can be increased by knocking out the transcription factor OsMYB1, and a certain theoretical basis is provided for cultivating high-quality purple rice with high anthocyanin content.

The invention belongs to the technical field of modern agriculture, and particularly relates to a method for creating pseudo male trachinotus ovatus. According to the method for creating the pseudo male trachinotus ovatus, alpha-naphthoflavone and 17 alpha-methyltestosterone are used in a combined mode, feeding induction is started from the 2-month-old period, and finally sperms can be observed in sexual glands of the genetic female trachinotus ovatus in the 8-month-old period. According to the method, the sexual gland of the genetic female trachinotus ovatus (the sexual gland normally develops into an ovary) can be reversed into the testis, in the 8-month-old period, the observed reversal efficiency is 63.6%, compared with single use of alpha-naphthoflavone, the sexual reversal proportion is increased by more than one time, the number and maturity of sperms of the pseudo male trachinotus ovatus are remarkably increased, and the sexual efficiency of the trachinotus ovatus is improved. And the success rate of subsequent all-female golden pomfret creation is greatly improved.

The invention discloses a triazine desulfurizer and a preparation method thereof, and belongs to the technical field of gas purification. The triazine desulfurizer is mainly prepared from the following raw materials in percentage by weight: 20 to 50 weight percent of triazine derivative, 10 to 15 weight percent of sterically hindered amine, 3 to 7 weight percent of stabilizer, 1 to 3 weight percent of synergist, 0.5 to 1.5 weight percent of penetrant, 0.5 to 1.5 weight percent of inhibitor, 1 to 2 weight percent of additive and the balance of water, the preparation method of the triazine derivative comprises the following steps: adding 2-(diphenylphosphino) ethylamine into a toluene solvent, adding a paraformaldehyde aqueous solution in batches under a stirring condition, and reacting for 2-8 hours to obtain the triazine derivative. According to the triazine desulfurizer and the preparation method thereof provided by the invention, the triazine derivative and the sterically hindered amine are taken as a host, and the stabilizer, the synergist, the penetrant, the inhibitor and the assistant are compounded, so that the scaling trend of the triazine desulfurizer in an oil and gas well can be slowed down, the dissolution rate of hydrogen sulfide and the mass transfer rate in a solution are increased, and the desulfurization reaction is promoted; the desulfurization effect and the desulfurization rate are improved, and meanwhile, a very good scale inhibition effect is also achieved.

The invention discloses a high-power compound plant sweetener and a preparation method thereof, and belongs to the technical field of food chemistry. Every 100 g of the high-power compound plant sweetening agent is prepared from the following components: 0.001 to 5 g of mogroside, 0.001 to 2 g of stevioside, 0.001 to 5 g of liquorice root extract, 0.0001 to 2 g of neohesperidin dihydrochalcone, 0.01 to 0.015 g of stachyose, 0.005 to 0.01 g of D-erythorbic acid, 0.005 to 0.01 g of ascorbic acid, and the balance of water-soluble dietary fiber. The pure plant high-power sweetener which is safe and healthy, has low energy and low carbohydrate and is rich in dietary fiber and protein is prepared, has obvious functions of healthy food, and is low in energy and less in carbohydrate and contains a certain amount of protein compared with cane sugar under the same condition.

The invention relates to a weather-resistant coating for a photovoltaic module and a preparation method of the weather-resistant coating, and belongs to the technical field of high polymer materials. The modified epoxy resin adhesive comprises the following components in parts by weight: 90-120 parts of modified resin, 5-25 parts of a curing agent, 10-30 parts of a composite filler, 5-10 parts of an auxiliary agent, 5-40 parts of a solvent and 0.5-3 parts of a plasticizer, a benzotriazole structure and a benzophenone group in the modified resin cooperate to enhance ultraviolet resistance and prolong service life, and introduced 1H, 1H-perfluoropropyl methacrylate is short in C-F bond and high in bond energy, so that moisture resistance and corrosion resistance are improved; long-carbon-chain silane in the composite filler modifies nano-zinc oxide, so that super-hydrophobicity is realized, cracks on a resin curing surface are filled, and corrosion resistance and wear resistance are enhanced; in addition, cinnamic acid endows the coating with excellent antibacterial ability, and the weather-resistant coating for the photovoltaic module prepared by the invention not only has good ultraviolet resistance, high temperature resistance and corrosion resistance, but also has excellent water-resistant and antibacterial effects.

The invention belongs to the field of edible oil preparation, and particularly relates to camellia diester edible oil assisting in reducing blood fat and a preparation method of the camellia diester edible oil. Walnuts, peas and sweet corn kernels are ground into thick liquid and then are subjected to sufficient enzymolysis, the obtained nutritional rapeseed oil is dispersed in mixed edible oil, and the prepared nutritional camellia diester oil mixture is rich in nutrition; the plant extract obtained by ultrasonic extraction is effectively adsorbed by the mixed jelly, and the obtained nano particle and nutrient camellia diester oil mixture assisting in reducing blood fat and promoting metabolism has an effective blood fat reducing effect; the antioxidant stability maintaining composition and the nanoparticles assisting in reducing blood fat and promoting metabolism are uniformly dispersed in the nutritional camellia diester oil mixture, and the prepared camellia diester edible oil assisting in reducing blood fat is rich in nutrition, does not increase the blood fat of a body after being eaten for a long time, does not damage the liver and kidney, and is not easy to deteriorate.

The invention provides antisense oligonucleotide of IL-17A mRNA (messenger Ribonucleic Acid) as well as application and a medicinal composition of the antisense oligonucleotide, and relates to the technical field of biological medicines. The nucleotide sequence of the antisense oligonucleotide of the IL-17A mRNA provided by the invention is as shown in SEQ ID NO.1, 3, 5 to 18, 20 to 23, 26 to 28 or 31. The antisense oligonucleotide can be specifically combined with IL-17A mRNA, RNase H is recruited after the antisense oligonucleotide is combined with the IL-17A mRNA, then degradation of the IL-17A mRNA is achieved, synthesis of IL-17A protein is prevented, and the antisense oligonucleotide can be used for preparing drugs for treating IL-17A related diseases.

The invention provides a nano medicine for promoting tumor cell copper death and a preparation method thereof, and the preparation method comprises the following steps: selecting a nano raw material carrier, combining copper ion protein, loading a copper ion chelating agent, carrying out ultrasonic wall breaking processing, carrying out surface decoration on the nano carrier, dispersing copper ions, and carrying out dry-method whole particle preparation. According to the nano-drug, the copper ions are carried by the specific nano-carrier, so that the copper ions can be selectively released in tumor cells, the tumor cells are induced to generate copper-dependent death, cell metabolism disorder can be caused by imbalance of a copper steady state, synthesis of iron-sulfur cluster proteins related to mitochondrial respiration is inhibited, and the tumor cell death rate is increased. According to the present invention, with the application of the polypeptide as the protein lipoic acylation modification upstream regulatory factor, the polypeptide can be directly combined with and induce the heteropolymerization, and the drug has good biocompatibility and good targeting property, and the polypeptide can be used as the protein lipoic acylation modification upstream regulatory factor.

The invention relates to the technical field of cosmetic raw materials, in particular to a skin care composition based on saccharomycetes fermentation lysate filtrate and a preparation method. The quaternary ammonium salt antibacterial product is obtained by adding potassium carbonate, a 1, 4-dibromobutane solution, a bio-phenol solution and trimethylamine. And taking absolute ethyl alcohol, a paeonol solution, a sodium hydroxide solution, a p-hydroxybenzaldehyde solution, absolute ethyl alcohol and an iodine elementary substance as raw materials to obtain a flavone product. And adding the flavonoid product, the quaternary ammonium salt antibacterial product and the anti-inflammatory chalcone into the embedding liquid to obtain the composite embedding product. And finally, adding the yeast fermentation lysate filtrate, the composite embedding product, hydrolyzed procyanidine, sodium hyaluronate, allantoin, butanediol, a preservative and deionized water to obtain a finished product. The finished product prepared by the invention has good antibacterial performance and anti-inflammatory performance, so that the finished product has a wide application prospect in the field of cosmetic raw materials.

The invention provides a preparation method of a high-selectivity semi-hydrogenation MOF (Metal Organic Framework) supported palladium catalyst for catalyzing acetylene. According to the invention, 2-methylimidazole is used as a ligand, Zn < 2 + > is used as a metal node, water is used as a solvent, and a ZIF-8-dia carrier is synthesized at room temperature by controlling the molar ratio of Zn < 2 + > to 2-methylimidazole; and depositing Pd < 2 + > on the ZIF-8-dia carrier by using a reducing agent to synthesize the MOF supported palladium catalyst. Strong electron interaction is formed between Pd nano-particles and a carrier loaded in the MOF loaded palladium catalyst, a rich Pd-N structure is constructed on the interface of the Pd nano-particles and the carrier, formation of Pd0 species is inhibited, the hydrogen activation capacity of the Pd nano-particles is reduced, excessive hydrogenation of acetylene is inhibited, and therefore the selectivity of ethylene is improved; the catalyst shows excellent catalytic performance in acetylene hydrogenation reaction, at 160 DEG C, the acetylene conversion rate reaches 100%, the ethylene selectivity is 85%, and the catalyst has excellent durability and stability.

The application discloses application of ginsenoside Rb1 in preparation of biological products for improving liver aging and abnormal lipid metabolism. The application research finds that ginsenoside Rb1 (20 mg / kg) can significantly improve the aging phenotype and lipid metabolism disorder of the aging liver through multi-target synergistic effect, and the mechanism is related to inhibition of lipid synthesis, improvement of lipid transport and promotion of lipid oxidation. The application provides a new drug candidate and action mechanism for intervention of aging-related liver diseases such as MASLD / MASH, and has an important clinical application prospect.

The invention relates to the technical field of treatment and health-care patches for external application, and discloses a preparation method of a light patch capable of removing waste gas, waste water and waste in a body. The black ointment comprises rhizoma alismatis, poria cocos, prepared rehmannia root, immature bitter orange, lysimachia christinae hance, astragalus membranaceus, folium sennae, pyracantha fortuneana, angelica sinensis, kelp, eclipta alba, rhizoma atractylodis, selfheal, salvia miltiorrhiza, rheum officinale, akebia stem, lotus leaf, ephedra and radix stephaniae tetrandrae. According to the present invention, the oil discharge patch contains 19 dampness removing and weight losing traditional Chinese medicine components, such that the oil discharge patch can be pasted on the navel position, and can enter the body through the transdermal absorption and the drug effect of the black plaster so as to produce the effect, such that the user can sweat and defecate after the patch, and the oil discharge patch can help the user to improve the metabolism, improve the spleen and stomach transportation, and discharge the useless objects in the body so as to provide the health care effect; useless waste gas, waste water and waste accumulated in the body can be discharged, so that the body can be naturally thinned, and a user can easily have a small waist.

The invention discloses an antibacterial and mildewproof leather material and a preparation method thereof. The antibacterial and mildewproof leather material comprises a leather base material as well as rare earth antibacterial and mildewproof powder AB-007, 2, 8-dihydroxyquinoline and 2-hydroxypyridine nitrogen oxide which are uniformly dispersed in the leather base material. The method ensures that the prepared leather has the excellent characteristics of high efficiency, durability, safety, environment friendliness and the like, and does not contain harmful heavy metal components. Meanwhile, wastewater generated in the production process can be recycled, wastewater discharge is effectively reduced, and the method has good energy-saving and environment-friendly characteristics.

This invention discloses the application of deacetylase activators targeting NSUN2 lactation modification in the preparation of drugs for treating hypopharyngeal cancer, belonging to the field of biomedical technology. This invention demonstrates for the first time that SIRT1 specifically eliminates the carcinogenic lactation modification of NSUN2 at lysine 470 (K470), thereby blocking the stability of ASNS mRNA and the de novo synthesis of asparagine, ultimately inhibiting the malignant proliferation of hypopharyngeal cancer cells, providing a novel therapeutic strategy for overcoming metabolic adaptation in hypopharyngeal cancer.

The invention relates to the technical field of bactericides for crops, in particular to a bacillus cereus-containing bactericidal composition and application thereof in prevention and control of camellia oleifera anthracnose. The active ingredients of the bactericidal composition comprise bacillus cereus WR-12 and diflumetofen sulfanilamide. According to the bactericidal composition, the synergistic bactericidal effect is enhanced by compounding a biological fungicide and a chemical fungicide, the development of drug resistance of pathogenic bacteria is delayed, the negative influence of chemical pesticides on the environment is reduced, green and efficient prevention and control of camellia oleifera anthracnose are achieved, and sustainable development of the camellia oleifera industry is promoted.

This invention discloses a compound traditional Chinese medicine powder inhaler for respiratory tract infections and its preparation method, relating to the field of pharmaceutical formulation technology. The compound traditional Chinese medicine powder inhaler for respiratory tract infections is composed of polysaccharide composite gel microspheres, forsythia, scutellaria, honeysuckle, and isatis root. The polysaccharide composite gel microspheres are composed of seaweed sulfated polysaccharide, lentinan, calcium chloride, and curcumin. Seaweed sulfated polysaccharide, lentinan, curcumin, and calcium chloride cross-link to form a three-dimensional network spherical structure, improving the particle morphology and flowability of the micropowder. Furthermore, due to its good hygroscopic and moisturizing properties, it competitively reduces the moisture absorption of the micropowder, preventing aggregation and further improving flowability. In addition, the gel microspheres have excellent adhesion, adhering to the infection site after entering the respiratory tract, reducing expulsion losses due to respiration, maintaining an effective drug concentration at the infection site, and improving therapeutic efficacy.

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine for treating hyperthyroidism, which comprises the following components by weight: 30 g of airpotato yam, 30 g of raw Chinese yam, 20 g of oyster, 15 g of prunella vulgaris, 15 g of bryozoatum, 15 g of raw astragalus membranaceus, 12 g of thunberg fritillary bulb, 12 g of kelp, 12 g of seaweed and 12 g of codonopsis pilosula. The traditional Chinese medicine is used for treating hyperthyroidism, has the effects of nourishing yin to lessen fire, calming the liver, suppressing yang, tonifying qi, calming the heart, soothing the nerves, relieving diseases, softening hard mass and regulating the immune function of a body, can avoid the influence of an iodine agent on a patient, and can be used for treating the patient.

The invention relates to the technical field of medical supplies, and discloses a medicated thread for treating chloasma and a preparation method and application thereof. The medicated thread for treating chloasma provided by the invention comprises a thread body and tranexamic acid infiltrated in the thread body. The medicine thread can continuously stimulate acupuncture points and meanwhile play a role in medicine treatment, the thread body, medicine and acupuncture point treatment are integrated, and the treatment effect on chloasma patients can be effectively improved.

This invention discloses a topical Chinese medicine preparation for treating erosive tinea pedis and its preparation method, belonging to the technical field of topical Chinese medicine preparations. The preparation consists of 15-25 parts clove, 10-20 parts alum, 20-30 parts Polygonum cuspidatum, and 10-18 parts Psoralea corylifolia, and is prepared into a spray using a 45% low-alcohol countercurrent extraction process. This invention achieves synergistic effects through a three-stage targeting mechanism: eugenol inhibits fungal CYP51A1 enzyme, blocking ergosterol synthesis (targeted enrichment rate 62.1%), resveratrol inhibits the NF-κB pathway, reducing inflammatory response, and psoralen activates the PI3K / AKT pathway, promoting epidermal repair (repair rate 69.2%). The alcohol concentration of the preparation is reduced to 45%, eliminating irritation to broken wounds. A single application takes only 1 minute, and a 7-day treatment course has a clinical efficacy rate of 84.7%, saving 320 yuan per person compared to traditional methods. This invention overcomes the shortcomings of existing drugs for treating erosive tinea pedis, such as strong irritation, cumbersome operation, and limited efficacy, and fills the gap in the category of specialized preparations, with significant social benefits and market prospects.

The present invention relates to a composition for lowering blood sugar, blood lipid and blood pressure and a preparation method thereof, belonging to the field of biotechnology, and the composition comprises a Cyclocarya paliurus flower extract, a chicken heart extract, a mandarin fish head extract and a Gracilaria extract; the Cyclocarya paliurus flower extract is obtained by enzymolysis of Cyclocarya paliurus flower by hemicellulase and bromelain, and then by ficin; the chicken heart extract is obtained by graded enzymolysis of chicken heart by pepsin and subtilisin; the mandarin fish head extract is obtained by fermenting mandarin fish head by Aspergillus niger, and then by trypsin; the Gracilaria extract is obtained by graded enzymolysis of Gracilaria by acid protease and trypsin. The composition has good effects of lowering blood sugar, blood lipid and blood pressure, can be used for preventing and treating cardiovascular and cerebrovascular diseases, softening blood vessels, improving microcirculation, reducing three high symptoms, and has no toxic side effects.

The present application belongs to the technical field of quorum quenching enzyme preparation, and particularly relates to a multi-target quorum quenching enzyme preparation and a preparation method and application thereof, such as being mainly used for inhibiting the virulence factors of Pseudomonas aeruginosa, and including acyl homoserine lactone acyltransferase AiiO protein and 3-hydroxy-4-oxoquinolone 2,4-dioxygenase AqdC protein, and the mass ratio of the two is 20:(1-25); such as being mainly used for inhibiting the virulence factors and the synthesis of biological membranes of Pseudomonas aeruginosa, and further including deferiprone, and the mass ratio of AiiO, AqdC and deferiprone is 20:(1-25):(0.695-2.78), the present application can target the Las, Rhl and PQS of Pseudomonas aeruginosa, the yield and stability of the prepared AqdC protein are both high, the two types of enzymes are used in combination after the regulation amount, and the virulence factors regulated by different quorum sensing pathways in Pseudomonas aeruginosa are effectively inhibited; the regulation amount of deferiprone is used in combination with the two types of quorum quenching enzymes, and the virulence and biological membranes of Pseudomonas aeruginosa can be effectively inhibited in a comprehensive manner.

The invention provides a method for improving the fermentation level of avilamycin, which comprises the following steps: step 1, seed tank culture: preparing a spore solution from maturely cultured streptomyces viridochromogenes, and inoculating the spore solution into a seed tank to obtain a mature seed solution; step 2, culturing in a fermentation tank: inoculating the grown mature seed liquid into a fermentation culture medium according to an amount which is 10 percent of the volume of the inoculated mature seed liquid in the fermentation tank, and supplementing an L-valine solution, a sodium acetate solution, phytine turbid liquid and liquefied starch in the culture process, so as to obtain avilamycin fermentation liquid. According to the method, key supplements including phytin and sodium acetate are supplemented, the utilization efficiency of avilamycin A precursors and carbon sources is effectively improved in the avilamycin fermentation process through the two key supplements, the fermentation level is improved to 7329 mu g / mL from 6126 mu g / mL, the fermentation level is improved, the maximum single impurity content is effectively controlled, and finally the quality of fermentation liquor is greatly improved.

The invention relates to an oat peptide rich in prebiotics and a preparation method thereof, and belongs to the technical field of biology, the product adopts oat peptide, prebiotics, wall-broken oat powder, white hyacinth bean powder, roxburgh rose powder and lotus seed powder as main raw materials; wherein the oat peptide is the oat peptide which is 5kDa or below and is obtained by sequentially carrying out step-by-step enzymolysis on oat protein through papain, snail protease and nattokinase; the white hyacinth bean powder is an extract obtained by performing common enzymolysis on white hyacinth beans through cellulase and pectinase and then sequentially performing step-by-step enzymolysis on the white hyacinth beans through trypsin and papain; the lotus seed powder is an extract obtained by performing common enzymolysis on peeled lotus seeds through cellulase and pectinase and then sequentially performing step-by-step enzymolysis through fig protease and papain. The product follows the functions of clearing, regulating and nourishing, all aspects are matched in a balanced mode, the digestion and absorption rate is increased, blood toxins and intestinal waste are removed, blood sugar and blood fat are reduced, immunity is improved, mood comfort is facilitated, and nerve soothing and sleep aiding are achieved; the effect is prominent, rapid and safe without side effects.