384 results about "Sulfanilamide" patented technology

The invention relates to the technical field of cationic etherifying agents, and discloses a quaternary ammonium salt type cationic etherifying agent and a preparation method thereof.3-chloro-2-hydroxypropyl trimethyl ammonium chloride and sulfaguanidine modified quaternized chitosan are added into a reactor and stirred, and the quaternary ammonium salt type cationic etherifying agent is obtained. Quaternary ammonium salt, guanidyl and chitosan groups contained in the sulfaguanidine modified quaternized chitosan all have better antibacterial effects; wherein the quaternary ammonium salt is adsorbed to the surfaces of bacteria, and hydrophobic groups are inserted into lipoid layers, so that the permeability of cell membranes is changed, the membrane structure is destroyed, intracellular substances are leaked, and the bacteria are dead; guanidyl can be combined with protein and nucleic acid in bacterial cells to interfere the normal metabolic process of bacteria and further inhibit growth and reproduction of the bacteria, so that a natural antibacterial effect is achieved; and the chitosan group has a relatively good antibacterial effect.

The invention discloses a preparation method of a high-dispersion and high-thermal-conductivity filler based on carbon black, and relates to the technical field of carbon black modification, and the preparation method specifically comprises the following steps: treating carbon black in a first acid solution to obtain activated carbon black; treating the single-walled carbon nanotube in a second acid solution to obtain an activated single-walled carbon nanotube; treating the activated single-walled carbon nanotube with a sulfanilamide solution to obtain a functionalized single-walled carbon nanotube; placing the graphene nanosheets in a third acid solution for treatment to obtain activated graphene nanosheets; the preparation method comprises the following steps: mixing amino silane hydrolysate and epoxy silane hydrolysate, adding activated carbon black, functionalized single-walled carbon nanotubes and activated graphene nanosheets, and treating to obtain a pre-modified filler; amino acid and a cross-linking agent are pre-polymerized to obtain an amino acid pre-polymerized solution, and the pre-modified filler is treated by the amino acid pre-polymerized solution to obtain the high-dispersion and high-thermal-conductivity filler. The method disclosed by the invention is simple to operate and low in energy consumption, the prepared filler is good in thermal conductivity and good in dispersity in a polymer matrix, and the thermal conductivity and the mechanical property of a polymer are greatly improved.

The invention relates to the technical field of solid waste treatment, in particular to a method for removing antibiotics and resistance genes in aerobic composting of chicken manure. Comprising the following steps: adding a composting auxiliary material into chicken manure to enable the carbon-nitrogen ratio to be (25-30): 1, and adjusting the initial moisture content to 55-65% to obtain an initial composting material; adding persulfate and zero-valent iron into the initial compost material, and uniformly mixing; loading the mixed material into a container for composting; during the composting period, stirring is performed regularly, and the aerobic composting time is 30-40 days. The method has the advantages that the persulfate advanced oxidation technology and the aerobic composting technology are combined, the potassium persulfate and the zero-valent iron are added to serve as the aerobic composting additive, the zero-valent iron can continuously activate the potassium persulfate, persulfate free radicals and hydroxyl free radicals are generated, and removal of antibiotics and antibiotic resistance genes is promoted; high-concentration oxytetracycline, sulfamethoxazole and ciprofloxacin in the chicken manure are effectively removed; and the abundance of antibiotic resistance genes with high risk levels is obviously reduced.

The invention provides a preparation method of an iron and nitrogen co-doped biomass-based carbon material, which can be applied to the technical fields of environmental functional materials and advanced oxidation. The preparation method comprises the following steps: obtaining target charcoal precursor powder; mixing the charcoal precursor powder with soluble ferric salt and urea to form initial mixed powder, adding water into the initial powder, and drying after water bath to obtain mixed powder; and heating and calcining the mixed powder according to preset process parameters to obtain the iron and nitrogen co-doped biomass-based carbon material. The prepared iron and nitrogen co-doped biomass-based carbon material FeOx has a high specific surface area and a rich pore structure, FeOx is uniformly dispersed on a nitrogen-doped carbon substrate, ozone catalytic activity and electron conduction performance are improved, and reactive oxygen species (ROS) can be efficiently generated to degrade sulfamethoxazole.

The invention discloses anti-cracking concrete and a preparation method thereof, and the anti-cracking concrete is prepared from the following raw materials in parts by weight: 400-450 parts of cement, 600-700 parts of fine aggregate, 900-1000 parts of gravel, 70-80 parts of a composite additive, 30-40 parts of modified fiber, 4-5 parts of a water reducing agent and 160-180 parts of water, the composite additive is prepared from fly ash, modified sepiolite, calcium sulphoaluminate and an air entraining agent; the modified sepiolite is obtained by taking sepiolite as a raw material, pretreating the sepiolite through a silane coupling agent and then sequentially reacting the pretreated sepiolite with sulfanilamide and dodecyl chloride. According to the invention, through the synergistic effect of the composite additive and the modified fiber, the comprehensive improvement of the crack resistance and mechanical strength of the concrete is realized, in the composite additive, the moderate expansion of calcium sulphoaluminate compensates the early shrinkage stress, the microbubble system formed by the air entraining agent relieves the stress concentration, and the dispersion effect of the polycarboxylate superplasticizer is matched, so that the crack resistance and mechanical strength of the concrete are improved. The hardened body forms a compact and uniform microstructure, and the tensile strength of the concrete is improved.

The invention is directed to an aqueous binder composition for mineral wool fibres made of a mixture of I) a phenol-urea-formaldehyde binder (PUF binder), and II) a carbohydrate binder comprising a component (a) in the form of one or more carbohydrates and a component (b) in the form of: (bi) one or more compounds selected from sulfamic acid, derivatives of sulfamic acid or any salt thereof, wherein component (a) is present in an amount of at least 20 % by weight based on the binder component solids. The aqueous binder composition is suitable for producing a mineral fibre product by contacting mineral fibres with the aqueous binder composition and curing the binder.

The invention belongs to the technical field of chemical sensing, and particularly relates to a Zn-MOF fluorescence detection probe as well as a preparation method and application thereof. The structural unit of the Zn-MOF fluorescence detection probe is [Zn2 (TPB) (BPDC-(OH) 2) 2]. (DMF). (H2O), wherein the BPDC-(OH) 2 is a 2, 5-dihydroxy terephthalic acid anion; the fluorescence detection probe belongs to a monoclinic system, the space group is C2 / c, and the Zn-MOF fluorescence detection probe has the characteristics of good selectivity, high sensitivity, high response speed and the like. The preparation method comprises the following steps: mixing 2, 5-dihydroxyterephthalic acid, 1, 2, 4, 5-tetra (4-pyridyl) benzene, zinc nitrate, N, N-dimethylformamide and deionized water, carrying out a heating reaction, filtering, and drying to obtain the Zn-MOF fluorescence detection probe. The preparation method has the advantages of easily available raw materials, simple operation and the like. The Zn-MOF fluorescence detection probe can be used for detecting sulfasalazine, realizes visual identification of SSZ according to the change of fluorescence intensity of the probe, can qualitatively determine SSZ in real time through a portable fluorescent lamp, and has important application value.

The invention provides application of sulfasalazine and a combined drug thereof in drug-resistant head and neck malignant tumors, which comprises the following steps: when the sulfasalazine is independently used, the sulfasalazine has a treatment effect on the drug-resistant head and neck malignant tumors and can delay the growth of the drug-resistant head and neck malignant tumors; combined use of sulfasalazine and chemotherapeutic drugs has a synergistic effect, and the sulfasalazine can be used for treating drug-resistant head and neck malignant tumors. The technical problem to be solved by the invention is to explore the drug activity of sulfasalazine in the treatment of drug-resistant head and neck malignant tumors and solve the limitation of drug resistance to treatment in the drug treatment process.

The invention relates to a microbial fuel cell and application thereof, in particular to a photocatalytic / microbial coupled anode microbial fuel cell and application thereof in enhanced degradation of sulfamethoxazole. Aiming at the degradation treatment of typical refractory antibiotics such as sulfamethoxazole, the invention provides a photocatalytic / microbial coupled anode microbial fuel cell which can induce a photo-generated hole generated by a photocatalyst through a biological electric field generated by microbial degradation of pollutants, thereby promoting the separation of photo-generated electron hole pairs of the photocatalyst, and further improving the degradation efficiency of the antibiotics. The problem that photo-generated electron hole pairs of a photocatalyst are easy to compound is solved. Meanwhile, due to the existence of the photocatalyst, the electron transfer between the anode electroactive microorganisms and the anode can be improved through the generation of photo-generated holes, and the extracellular electron transfer of the microorganisms is enhanced. When being used for degrading sulfamethoxazole, the photocatalytic / microbial coupled anode microbial fuel cell disclosed by the invention has an extremely important scientific research value and a wide practical application prospect.

The invention discloses a ZIF-based catalytic ceramic membrane, a preparation method and application of the ZIF-based catalytic ceramic membrane in water treatment, and belongs to the technical field of environmental functional materials and membrane separation. According to the method, a bimetallic precursor solution and an organic ligand solution are adopted, ZIF crystals grow on a ceramic membrane in situ, and then the ZIF-based catalytic ceramic membrane with Co-Co metallic bond and Co-N coordination double active sites is prepared through high-temperature pyrolysis and acid pickling treatment. The prepared ZIF-based catalytic ceramic membrane has high porosity (the specific surface area is greater than or equal to 360 m < 2 > / g) and strong binding force, can stably operate for 3720 minutes or more in a continuous flow reaction, has a removal rate of up to 90% for electronic-enriched pollutants such as sulfamethoxazole and the like, and can resist water quality interference. The process is simple, active sites are controllable, and the method is suitable for high-efficiency low-consumption treatment of industrial wastewater.

The invention relates to the technical field of cationic etherifying agents, and discloses a quaternary ammonium salt type cationic etherifying agent and a preparation method thereof. The invention provides a quaternary ammonium salt type cationic etherifying agent by adding 3-chloro-2-hydroxypropyltrimethylammonium chloride and sulfaguanidine modified quaternized chitosan into a reactor, stirring, and obtaining the quaternary ammonium salt type cationic etherifying agent. The quaternary ammonium salt, guanidine group, and chitosan group contained in the sulfaguanidine modified quaternized chitosan all have good antibacterial effects; wherein the quaternary ammonium salt is adsorbed onto the bacterial cell surface, and the hydrophobic group is inserted into the lipid layer, thereby changing the permeability of the cell membrane, destroying the membrane structure, causing the leakage of intracellular substances, and causing bacterial death; the guanidine group can interfere with the normal metabolic process of the bacteria by combining with proteins and nucleic acids in the bacterial cells, further inhibiting the growth and reproduction of the bacteria, thereby playing a natural antibacterial effect; and the chitosan group itself has a good antibacterial effect.

The invention discloses a method for enhancing co-metabolism degradation of antibiotics in ammoxidation sludge, and belongs to the technical field of sewage treatment. According to the method, ammonia oxidation sludge is enriched firstly, artificially synthesized sewage is used as inlet water of an ammonia oxidation sludge enrichment reactor, the reactor is operated by adjusting the pH value to be acidic, sulfamethoxazole with different concentrations in the inlet water is treated in stages, co-metabolism of the ammonia oxidation sludge is enhanced, and sulfamethoxazole degradation is enhanced under the long-term operation condition; the ammonia nitrogen removal rate is not obviously inhibited. The method provided by the invention not only can remove ammonia nitrogen in sewage, but also can efficiently and stably degrade antibiotics, and can reduce propagation and invasion of pathogens in nature, thereby protecting biodiversity and stability of an ecological system.

The invention relates to a monoatomic catalytic material capable of efficiently degrading sulfamethoxazole as well as a preparation method and application of the monoatomic catalytic material. The preparation method comprises the following specific steps: dispersing 2 mmol of cobalt chloride hexahydrate, 0.5 g of tannic acid, 5 g of melamine and 5 g of cyanuric acid in 400 mL of water, and magnetically stirring at room temperature overnight; and pouring supernate out of the solution, drying in an air dry oven at 60 DEG C overnight, and grinding with an agate mortar. And carrying out annealing reaction in a nitrogen tube furnace at 600 DEG C for 2 hours. The prepared black charcoal is ground by an agate mortar, then is stirred and washed by a 0.5 M sulfuric acid solution at room temperature for 12 hours, and then is subjected to suction filtration and washing by water until the filtrate is nearly neutral in pH. And finally, drying in a vacuum drying oven, grinding by using an agate mortar, and filling into a pipe to obtain the Co2TA0.5 catalyst. The simple Co2TA0.5 catalyst provided by the invention has more excellent catalytic performance, and can activate PMS to efficiently remove SMX in water.

The invention discloses a preparation method of a sludge biochar filler, which comprises the following specific steps: air-drying sludge, crushing and sieving; iron powder, the treated sludge and kaolin are weighed and put into a granulator, distilled water is added, and a ceramic blank with the diameter being 4-8 mm is prepared; and naturally airing the ceramic blank, and carrying out oxygen-isolated calcination in a muffle furnace to obtain the sludge biochar filler. The invention also discloses an artificial wetland coupled with micro-electrolysis, and the iron powder is organically combined with the sludge and the kaolin, so that the removal rate of sulfadiazine in a water body is increased; the sludge biochar filler prepared by the constructed wetland is combined with the filling mode disclosed by the invention, so that the removal rate of sulfadiazine can reach up to 100%. According to the constructed wetland, the community structure of microorganisms in the constructed wetland and the life activity of the microorganisms are adjusted by adjusting the filler design and the operating condition, so that the removal effect of the constructed wetland on pollutants is improved.

The invention belongs to the technical field of environmental treatment, and particularly relates to a synthesis method of Fe and N co-doped nanotube-coated microspheres and application of the Fe and N co-doped nanotube-coated microspheres in catalytic degradation of organic pollutants. The preparation method comprises the following steps: by taking guanosine as a precursor, adding sulfuric acid and ferric nitrate nonahydrate to carry out hydrothermal reaction, and carrying out pyrolysis after the reaction, thereby obtaining the spherical structure catalyst wrapped in a carbon tube shape. The nanotubes are wound on the surfaces of the microspheres to form a 3D structure, so that the contact area with reactants is increased, and adsorption and mass transfer are facilitated; the nanotubes on the surface promote the uniform distribution of active substances, reduce the agglomeration of metals and facilitate the proceeding of a catalytic reaction; the catalyst is rich in aperture, and is beneficial to electron transfer and active site exposure. The morphology does not need to use an additional template agent, the catalyst is used for activating PMS to degrade sulfamethoxazole, excellent performance is achieved under interference of all pH values, inorganic salt and humic acid, the application range is expanded to tetracycline, enrofloxacin and ofloxacin, and good effects are achieved.

The invention relates to the technical field of high polymer materials, and discloses antibacterial cellulose modified polylactic acid, triazole compounds have excellent activity in the antifungal aspect, and sulfanilamide groups can influence nucleic acid metabolism of thalli and synthesis of dihydrofolic acid so as to play a bacteriostatic role. Under the synergistic effect of a sulfanilamide group and a triazole group, the synthesized antibacterial cellulose has excellent antibacterial activity, the antibacterial group is introduced in a grafting manner, so that the long-acting antibacterial activity can be maintained, the polylactic acid is modified by using the cellulose, and due to the large length-diameter ratio of the cellulose and mutual overlapping of the cellulose, the antibacterial activity of the polylactic acid is improved. A good net structure is formed in a polylactic acid matrix through hydrogen bonds and Van der Waals force, so that a toughening effect on polylactic acid can be achieved, and the modified polylactic acid not only has excellent antibacterial activity, but also has better mechanical properties and thermal stability.

The present invention discloses a method for degrading sulfamethoxazole using QXT-31-Mn, which belongs to the field of sewage treatment technology. QXT-31-Mn was deposited with the General Microbiology Center of the China Culture Collection Administration on December 3, 2024, with the deposit number CGMCC No. 32889 and the deposit address at No. 3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The taxonomic name is Arthrobacter sp. The present invention utilizes QXT-31-Mn to produce a safer and more environmentally friendly cathode material that can efficiently degrade SMX.

The invention belongs to the technical field of environmental microorganisms, and particularly relates to a sulfamethoxazole anaerobic degradation strain SA-9 and application thereof. According to the present invention, anaerobic sludge collected from the vicinity of a farm is subjected to enrichment domestication, separation and purification to obtain the bacterial strain capable of efficiently and rapidly performing anaerobic degradation on sulfamethoxazole (SMX), and the morphological and molecular biological identification results show that the bacterial strain belongs to Cupidesulfavibrio, and is named as Cupidesulfavibrio sp.SA-9; the strain can rapidly degrade SMX under an anaerobic condition, and the degradation half-life period is 7.6 d. The strain disclosed by the invention can be used as a biodegradation bacterium to be applied to bioremediation of SMX polluted environments, equipment and facilities.

The invention is suitable for the technical field of fine chemical engineering, and provides a synthesis method of sulpiride impurity 2-hydroxy-5-sulfanilamide benzamide, which comprises the following specific steps: Step 1, taking salicylic acid as a raw material, taking DMF as a catalyst, and carrying out acylation reaction with thionyl chloride to obtain acylation liquid, and entering the next process; 2, ammoniating the acylation liquid with ammonia water at a low temperature to obtain salicylic acid formamide, and drying to obtain an intermediate 1; 3, TMS-Cl is used for protecting phenolic hydroxyl groups, then chlorosulfonic acid is dropwise added, a chlorosulfonation reaction is carried out, and an intermediate 2 solution is obtained after the reaction is completed; and Step 4, dropwise adding the solution of the intermediate 2 into stronger ammonia water for reaction, carrying out suction filtration, and recrystallizing with ethanol to obtain the sulpiride impurity 2-hydroxy-5-sulfanilamide benzamide. The route synthesis is simple, and the quality can reach 95% or above; in addition, the method has the advantages of cheap and easily available raw materials, mild reaction conditions, low energy consumption, simple process structure, easy operation and the like.

The invention discloses multi-walled carbon nanotube functionalized sludge biochar as well as a preparation method and application thereof. The method comprises the following steps: firstly, mixing sludge biochar prepared by anaerobic pyrolysis with a multi-walled carbon nanotube, and carrying out ball milling treatment, so as to prepare the sludge biochar functionalized by the multi-walled carbon nanotube; the multi-walled carbon nanotube functionalized sludge biochar prepared by the invention can efficiently activate peroxymonosulfate to degrade trace antibiotics in a water body, and the removal rate of sulfamethoxazole can reach 96% when the reaction is carried out for 60 minutes. According to the method, harmless treatment and resource utilization of the sludge can be realized, and meanwhile, efficient removal of antibiotics in the water body is also realized.

Disclosed is a new pharmaceutical composition for oral administration containing sulfasalazine and / or a sulfasalazine organic salt, production processes and uses, in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and / or the gastro-intestinal tract.

The invention relates to the technical field of biological sewage treatment, and particularly discloses a process for combined treatment of antibiotic wastewater by a compound microorganism-MBR (Membrane Bioreactor) membrane. The invention provides a process for combined treatment of antibiotic wastewater by a compound microorganism-MBR (Membrane Biological Reactor) membrane, which comprises the following steps of: performing directional domestication and toxicity screening on activated sludge through COD (Chemical Oxygen Demand) gradient increase and decrease and removal rate control, and constructing a microbial community resistant to sulfamethoxazole impact; further, a compound bacteria solution composed of marine Arfiv bacteria and Rhodopseudomonas faecalis is introduced, so that synergistic degradation of high COD and sulfamethoxazole is realized under a proper pH condition, and the COD removal rate is still kept at a relatively high level when the concentration is increased; and the tail end is matched with MBR membrane separation, and efficient biodegradation and efficient solid-liquid separation are coupled, so that the sulfamethoxazole and COD in the wastewater are efficiently removed under the conditions of low drug consumption and near neutrality.

The invention discloses a B-doped iron monatomic catalyst, and a preparation method of the B-doped iron monatomic catalyst comprises the following steps: uniformly dispersing urea and a B source in a first solvent to obtain a mixed solution, uniformly mixing a Fe source solution, a polyether F127 solution and the mixed solution, and performing freeze drying to obtain a precursor; and calcining the precursor at 780-820 DEG C in a nitrogen or inert gas atmosphere to obtain the B-doped iron monatomic catalyst. According to the B-doped iron monatomic catalyst, the fenton-like sulfamethoxazole degradation efficiency is remarkably improved, the PMS activation capacity is enhanced, 100% of sulfamethoxazole can be degraded within 5 min, and after 10 min, sulfamethoxazole can be completely mineralized into carbon dioxide and water, so that the degradation efficiency of sulfamethoxazole is improved. The invention provides an effective and feasible method in the field of improving and degrading micropollutants such as sulfamethoxazole and the like, and the method also has relatively good degradation capability on microplastics.

The invention belongs to the technical field of medical chemical component detection, and discloses a method for determining lead salt in a sulfadiazine zinc raw material, which comprises the following steps: S1, measuring a lead single element standard solution, and diluting with a nitric acid solution to obtain a linear solution containing different concentrations of lead; s2, weighing a sample, and adding nitric acid for digestion and dissolution to obtain a sulfadiazine zinc test solution; s3, measuring the same amount of nitric acid in the step S2, and performing digestion and dissolution to obtain a sample blank solution; s4, respectively injecting the linear solutions in the step S1 into an atomic absorption spectrophotometer, and making standard koji according to a preset heating program; and S5, respectively injecting the sulfadiazine zinc test solution and the sample blank solution into an atomic absorption spectrophotometer, and determining the lead content in the sulfadiazine zinc according to a preset heating program. The problems that an existing method is low in sensitivity and cannot meet limit requirements are solved.

The present invention discloses an anti-sulfadiazine nano-antibody and its application, belonging to the field of nano-antibody technology. In order to provide a nano-antibody for detecting sulfadiazine that has a small molecular weight, strong penetrating power, good stability, strong antigen binding ability, and can recognize antigen epitopes that are difficult for conventional antibodies to recognize. The present invention provides a nano-antibody for detecting sulfadiazine, the amino acid sequence of CDR1 of the variable region of the nano-antibody is shown as SEQ ID NO.6, the amino acid sequence of CDR2 of the variable region of the nano-antibody is shown as SEQ ID NO.7, and the amino acid sequence of CDR3 of the variable region of the nano-antibody is shown as SEQ ID NO.8. The indirect competitive ELISA method established by the present invention is a simple, rapid, sensitive, and low-cost immunoassay method, which has great application prospects in the detection of sulfadiazine residues in animal-derived foods.

The invention discloses a method for efficiently removing sulfamethoxazole in water by combining trichloroisocyanuric acid and ferrate, and aims to solve the problem that ferrate has a poor degradation effect on antibiotic-containing sewage. The method for removing sulfamethoxazole in water comprises the following steps: 1, dissolving ferrate in a buffer solution with the pH value of 7-9 to obtain a ferrate solution; 2, dissolving trichloroisocyanuric acid in a buffer solution with the pH value of 7-9 to obtain a trichloroisocyanuric acid solution; 3, adding the ferrate solution and the trichloroisocyanuric acid solution into the wastewater containing the sulfamethoxazole; and 4, carrying out a stirring reaction on the wastewater containing sulfamethoxazole at room temperature. The trichloroisocyanuric acid and the ferrate are combined for use, the ferrate can oxidize free chlorine to generate Cl., meanwhile, Cl. Can also oxidize iron ions to generate intermediate products such as Fe (IV), a redox cycle with high reactivity can be formed between the trichloroisocyanuric acid and the ferrate, and the degradation efficiency of sulfamethoxazole is improved.

The invention discloses a sulfaguanidine modified inorganic tin-based perovskite light-emitting diode and a preparation method thereof, and belongs to the field of luminescent material preparation, the preparation method comprises the following steps: preparing a perovskite precursor solution which comprises cesium iodide, stannous iodide, sulfaguanidine and an organic solvent; applying the perovskite precursor solution to a substrate to form a wet film; carrying out annealing treatment on the wet film so as to form a perovskite light-emitting layer containing CsSnI3 perovskite and sulfaguanidine; a hole transport layer is formed on an anode conductive substrate, and a perovskite light-emitting layer is adopted on the hole transport layer; and sequentially forming an electron transport layer, an electron injection layer and a cathode electrode on the perovskite light-emitting layer. The process is simple and suitable for popularization and application.

The application relates to the technical field of high polymer materials, and discloses a phosphorus-containing flame-retardant epoxy resin and a preparation method thereof, which comprises the following components by weight: 50-65 parts of bisphenol A type epoxy resin, 4-6 parts of phosphorus-containing modified benzimidazole, 2-3 parts of epoxy-based sulfanilamide thiazole and 2-4 parts of m-phenylenediamine curing agent. The bisphenol A type epoxy resin is added into a stirrer, heated, and then the phosphorus-containing modified benzimidazole and the epoxy-based sulfanilamide thiazole are continuously added into the stirrer; after cooling, the m-phenylenediamine curing agent is continuously added into the stirrer, and then curing is carried out, so that the phosphorus-containing flame-retardant epoxy resin is obtained. The phosphorus-containing flame-retardant epoxy resin has good flame-retardant effect.

The utility model relates to the technical field of medicine raw material crushing and screening devices, and discloses a raw material crushing and screening device for compound sulfamonomethoxine sodium, which comprises a crushing mechanism, a primary screening mechanism arranged at the bottom end of the crushing mechanism and used for primarily screening the compound sulfamonomethoxine sodium raw material, and a secondary screening mechanism arranged at the bottom end of the crushing mechanism, a secondary screening mechanism used for conducting secondary screening on the compound sulfamonomethoxine sodium raw materials is arranged in the box body. The raw material of the compound sulfamonomethoxine sodium is crushed by arranging the crushing mechanism, and the crushed raw material of the compound sulfamonomethoxine sodium is primarily screened by arranging the primary screening mechanism; the secondary screening mechanism is arranged to conduct secondary screening on the raw materials of the compound sulfamonomethoxine sodium subjected to primary screening, and the function of conducting multiple times of screening on the raw materials of the compound sulfamonomethoxine sodium is achieved.