40 results about "Sulfaquinoxaline" patented technology

The invention discloses 1,4-dioxo-2-(1-ethoxy)-3-hydroxymethyl-sulfaquinoxaline and a preparation method and an application thereof. The 1,4-dioxo-2-(1-ethoxy)-3-hydroxymethyl-sulfaquinoxaline is shown as a formula (1). The preparation method of a product (I) comprises the following steps of: reducing mequindox serving as a raw material to obtain 1,4-dioxo-3-methyl-2-(1-hydroxymethyl)sulfaquinoxaline; mixing and reacting with acetic anhydride and pyridine to obtain 1,4-dioxo-3-methyl-2-(1-hydroxymethyl)sulfaquinoxaline; reacting an obtained product with acetic anhydride to obtain 1-oxy-2-(1-ethoxycarbonyl oxygen ethyl)-3-(1-ethoxycarbonyl oxygen ethyl)-sulfaquinoxaline; oxidizing to obtain 1,4-dioxo-2-(1-ethoxycarbonyl oxygen ethyl)-3-(1-ethoxycarbonyl oxygen ethyl)-sulfaquinoxaline; and performing hydrolysis through an alkali liquor to obtain the product (I). The product (I) can be taken as a residual marker of maquindox in target animal in-vivo metabolism or a standard product or a reference product for detecting maquindox residue in an animal-derived food.

The invention provides a blue-light-emitting up-conversion material. Yttrium acetate C6H17O10Y, ytterbium acetate C6H9O6Yb.4H2O and thulium acetate C6H9Tm.xH2O serve as main raw materials for preparation. The blue-light-emitting up-conversion material is mainly characterized in that up-conversion fluorescence nano-particles NaYF4:Yb,Tm (the excitation wavelength is 980 nm and the emission wavelength is 477 nm) mark a sulfaquinoxaline monoclonal antibody and serve as a signal probe, polystyrene magnetic microspheres connected with a sulfaquinoxaline coating antigen serve as an induction probe, and thus a competitive immunoassay based on up-conversion particle marking and magnetic nano-particle quick separation is structured to detect sulfaquinoxaline in food, and the detection limit is 0.1 ng mL-1. The blue-light-emitting up-conversion material has the following advantages that detection steps are simple, separation is achieved through the action of an additionally-added magnetic field, operation steps are greatly simplified, and the detection time is shortened; sensitivity is good; sample pretreatment is easy, fast and environmentally friendly.

The invention discloses a solvent-free method for preparing sulfaquinoxaline, which comprises the following steps: at room temperature, adding industrial sulfanilamide, chloride and potassium carbonate into a condensation reaction kettle, and uniformly stirring; heating the materials in the condensation reaction kettle to 195-200 DEG C, and reacting for 8-9 hours; adding drinking water into the condensation reaction kettle, and stirring until the materials are completely dissolved; pressing into a decoloration reaction kettle; adding activated carbon, stirring and decolorizing for 8-15 minutes; carrying out filter pressing, namely pressing filtrate into a neutralization and crystallization reaction kettle; controlling the material temperature at 80-85 DEG C, dropwise adding a hydrochloricacid solution within 45-60 minutes, and adjusting the pH value to 1.8; slowly stirring and growing crystal for 30 minutes; controlling the temperature of the materials to be 80-85 DEG C, and continuously dropwise adding a hydrochloric acid solution to adjust the pH value to be 1.0; slowly stirring and growing crystal for 60 minutes; discharging, separating crystals and mother liquor, and spin-drying; washing with water, spin-drying, discharging, crushing, and drying at 110-120 DEG C until the water content is less than or equal to 1.0%; and collecting powder to obtain a sulfaquinoxaline dry product.

The invention relates to an amprolium hydrochloride-ethopabate-sulfaquinoxaline medicine composition powder which is added with sodium carbonate as a cosolvent of sulfaquinoxaline, and aims to solve the problem of solubility. Aerosol is added as an anti-caking agent for reducing the air-slaking and caking phenomenon in the storage process and prolonging the effective period; meanwhile with addition of a sweet wormwood extract and / or antifebrile dichroa extract with anti-coccidium active components, the relative weight increase rate of chicken is increased, the oocyst discharge rate is reduced, and the intestinal tract diseases are reduced. The invention further relates to a preparation method of the medicine composition powder. The preparation method is simple to operate, free of residue in the preparation process, and capable of effectively preparing an amprolium hydrochloride-ethopabate-sulfaquinoxaline composition which is good in solubility, free of slaking or caking in the storage process, good in treatment effect and long in expiry date. The medicine composition powder is applied to preparation of medicines for treating avian coccidiosis and is remarkable in medicine effect.

The invention discloses a sulfaquinoxaline cobalt-nickel nano composite material and a preparation method thereof. According to the invention, a certain amount of a metal salt solution is added to a sulfaquinoxaline-containing organic ligand, and the obtained product is stirred at a certain temperature. After the treatments of microwave reaction, ultrasonic dispersion, centrifugal separation, washing, and drying, a corresponding metal-ligand nano composite material is obtained. The method is simple in preparation process, low in cost and suitable for mass production. Through selecting different solvents, controlling the amounts of reactants, the reaction time and the reaction temperature, the particle size of sulfaquinoxaline cobalt-nickel nano composite material and the dispersibility thereof are effectively controlled. The prepared sulfaquinoxaline cobalt-nickel nano composite material is a functionalized composite material containing cobalt and nickel, and is stable in performance. The material can be used for catalyzing the C-C bond coupling reaction, and is high in catalytic efficiency. Therefore, the sulfaquinoxaline cobalt-nickel nano composite material has a wide application prospect in the catalysis field.

The invention discloses a nickel micro nanoparticle and a preparation method thereof. The preparation method comprises the following steps: adding a certain quantity of nickel salt solution into a solution which contains sodium sulfaquinoxaline, performing centrifugation on products after reaction and aging at a certain temperature, leaving precipitate, washing the precipitate respectively with deionized water and ethanol, performing ultrasonic dispersion, and drying, so as to prepare the corresponding sulfaquinoxaline nickel micro nanoparticle. According to the preparation method, the preparation of metal micro nanoparticles through reaction to different nickel salts and sulfaquinoxaline is successfully realized, metal-ligand micro nanoparticles with uniform particle size are obtained, and excellent physical and chemical properties are provided. The sulfaquinoxaline nickel micro nanoparticle as a catalyst has good catalytic activity and wide application prospects in the field of catalysis. In a whole preparation process, the operation is simple, the cost of raw materials is low, the equipment investment is low, and mass production is facilitated.

The invention provides composite photocatalytic fibers and a preparation method thereof. The preparation method includes: spinning a composite light catalyst and polyester polymer to obtain precursor fibers; performing exposing treatment on the composite light catalyst in the precursor fibers to obtain the composite photocatalytic fibers. The composite photocatalytic fibers have the advantages that the polyester polymer and the composite light catalyst are used as the raw materials, the raw materials are spun into the precursor fibers, and then the composite light catalyst in the precursor fibers is exposed to allow the fibers to have photocatalytic activity; experiment results show that the sulfaquinoxaline degradation rate of the composite photocatalytic fibers is quite high, and all sulfaquinoxaline can be degraded in about 2.5 hours; a circulation cycle lasts 5 minutes, and the composite photocatalytic fibers can still keep good degradation activity after 15 circulations.

The invention discloses a sulfaquinoxaline process wastewater recycling method, which comprises the following steps: firstly, mixing and stirring sulfanilamide, 2-chloroquinoxaline and potassium carbonate, and then sequentially carrying out activated carbon decoloration, filtration, neutralization precipitation and filtration to prepare solid sulfaquinoxaline and process wastewater, adding dichloromethane into the process wastewater to extract organic matters in the process wastewater so as to form a water phase and an organic phase, and finally respectively treating the water phase and the organic phase, the industrial sulfanilamide and sulfaquinoxaline mixture capable of being repeatedly used for condensation reaction, high-purity potassium chloride solid, reusable dichloromethane and recyclable secondary mother liquor are respectively obtained, so that zero discharge of process wastewater is realized, wastes generated in the production process are harmless, the discharge amount of pollutants is reduced, and the production cost is reduced. The environment is effectively protected and resources are saved.

The invention discloses catalytic oxidation application of sulfaquinoxaline cobalt compound. The compound is characterized by being cobalt compound with catalytic oxidation activity on benzoin; a molecular formula of the cobalt compound is C38H32N10O5S2Co, a crystal system is monoclinic, a space group is P2(1) / c, cell parameters are shown in a following image, the alpha is equal to 90 degrees, thebeta is equal to 100.848 degrees, and the gamma is equal to 90 degrees. The compound is prepared from cobalt salt, sulfaquinoxaline and 2,2'-dipyridyl and by mixed reaction according to a certain proportion and has the advantages of defined spatial structure, accurate molecular formula and simple synthesizing steps. The prepared cobalt compound disclosed by the invention shows good catalytic oxidation activity on benzoin and has a wide application prospect of serving as a potential catalytic active material.