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Compound sodium sulfaquinoxaline composition for treating coccidiosis in young rabbits, and preparation method thereof

A technology of sulfaquinoxaline sodium and young rabbit coccidiosis, which is applied in the field of animal medicine, can solve the problems of low drug bioavailability, decreased drug absorption and transport ability, and high irritability of young rabbits. Uniform mixing in one step, significant curative effect, simple preparation

Inactive Publication Date: 2013-03-20
QINGDAO LVMAN BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the drug routes use the way of mixing materials or drinking water. Since it is difficult for young rabbits to eat and drink after illness, the ability of drug absorption and transfer is reduced. The stress is also great, the effect is not very good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A compound sulfaquinoxaline sodium composition and preparation method thereof for the treatment of coccidiosis in young rabbits, carried out as follows: (each part is calculated by 10g)

[0025] (1) After pulverizing the various ingredients in the prescription respectively, pass through an 80-mesh sieve;

[0026] (2) Weigh 2 parts of sodium sulfite and 2 parts of EDTA-2Na according to the ratio of parts by weight, dissolve them in distilled water in turn, stir evenly, then add 150 parts of sodium citrate, and mix for 5-10 minutes until uniform;

[0027] (3) Weigh 5 parts of toltrazuril, 40 parts of sulfaquinoxaline sodium, and 8 parts of trimethoprim lactate according to the ratio of parts by weight, add them to the mixture obtained in (2), mix for 5 to 10 minutes, and finally Add 15 parts of sodium carboxymethyl cellulose, stir evenly, and then filter.

Embodiment 2

[0029] A compound sulfaquinoxaline sodium composition and preparation method thereof for the treatment of coccidiosis in young rabbits, carried out as follows: (each part is calculated by 10g)

[0030] (1) After pulverizing the various ingredients in the prescription respectively, pass through an 80-mesh sieve;

[0031] (2) Weigh 3.5 parts of sodium sulfite and 3.5 parts of EDTA-2Na according to the ratio of parts by weight, dissolve them in distilled water in turn, stir evenly, then add 200 parts of sodium citrate, and mix for 5-10 minutes until uniform;

[0032] (3) Weigh 7.5 parts of toltrazuril, 50 parts of sulfaquinoxaline sodium, and 10 parts of trimethoprim lactate according to the weight ratio, add them to the mixture obtained in (2), mix for 5 to 10 minutes, and finally Add 20 parts of sodium carboxymethyl cellulose, stir evenly and filter to obtain the product.

Embodiment 3

[0034] A compound sulfaquinoxaline sodium composition and preparation method thereof for the treatment of coccidiosis in young rabbits, carried out as follows: (each part is calculated by 10g)

[0035] (1) After pulverizing the various ingredients in the prescription respectively, pass through an 80-mesh sieve;

[0036] (2) Weigh 5 parts of sodium sulfite and 5 parts of EDTA-2Na according to the ratio of parts by weight, dissolve them in distilled water in turn, stir evenly, then add 250 parts of sodium citrate, and mix for 5-10 minutes until uniform;

[0037] (3) Weigh 10 parts of Toltrazuril, 60 parts of Sulfaquinoxaline Sodium, and 12 parts of Trimethoprim Lactate according to the ratio of parts by weight, add them to the mixture obtained in (2), mix for 5 to 10 minutes, and finally Add 25 parts of sodium carboxymethyl cellulose, stir evenly, and then filter.

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Abstract

The invention relates to a compound sodium sulfaquinoxaline composition for treating coccidiosis in young rabbits. The compound sodium sulfaquinoxaline composition is prepared by mixing the following ingredients in parts by weight: 0.5-1 part of toltrazuril, 4-6 parts of sodium sulfaquinoxaline, 0.8-1.2 parts of trimethoprim lactate, 15-25 parts of sodium citrate, 1.5-2.5 parts of sodium carboxymethyl cellulose, 0.2-0.5 part of sodium sulfite, 0.2-0.5 part of EDTA (Ethylene Diamine Tetraacetic Acid)-2Na, and a plurality of parts of distilled water. The compound sodium sulfaquinoxaline composition has the beneficial effects of being reasonable in formula, and simple to prepare, unique in medicine application mode, obvious in curative effect, and having special effects in treating the coccidiosis in young rabbits, proved clinically.

Description

technical field [0001] The invention relates to a compound sulfaquinoxaline sodium composition for treating young rabbit coccidiosis and a preparation method thereof, belonging to the field of animal medicine, in particular to a compound sulfaquinoxaline sodium composition for treating young rabbit coccidiosis and its preparation method Preparation. Background technique [0002] Young rabbit coccidiosis is a common infectious disease caused by coccidia that is the most harmful to the rabbit industry. The disease can break out and spread throughout the year. Clinically, it is characterized by diarrhea and red feces. Pathologically, it is mainly characterized by It is characterized by intestinal hemorrhage, and the mortality rate can be as high as 60%. The growth and development of the recovered rabbits are hindered, the feed remuneration decreases, the body resistance decreases, and it is prone to other diseases, which is very harmful to the rabbits. [0003] The pathogen of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/635A61K31/53A61K31/505A61P33/02
Inventor 周庆福刘文利
Owner QINGDAO LVMAN BIOLOGICAL ENG
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