76 results about "Trichloroacetic acid" patented technology

The invention discloses a method for accurately determining the content of trimethylamine, diethylamine and triethylamine in animal-derived traditional Chinese medicinal materials, which comprises the following steps: mixing alkali liquor and n-tetracosane in a headspace bottle, heating to completely dissolve the n-tetracosane, and standing until the n-tetracosane layer is solidified to seal the alkali liquor below the n-tetracosane layer; animal-derived traditional Chinese medicinal materials are crushed, sieved and dispersed in a trichloroacetic acid aqueous solution, centrifugation is performed after homogenization, supernate is collected, volume metering is performed, and a sample extracting solution is obtained; adding the sample extracting solution above the n-tetracosane layer in the headspace bottle, sealing by a gland, placing on an automatic sampler, sucking gas at the upper part of the headspace bottle, analyzing by a gas chromatograph-triple quadrupole mass spectrometer, and obtaining the contents of trimethylamine, diethylamine and triethylamine in the animal-derived traditional Chinese medicinal materials by an external standard method. The method is accurate and reliable in quantitative result, high in sensitivity and high in analysis efficiency, derivation is assisted by the phase change material n-tetracosane, the phenomenon that the quantitative accuracy is poor due to the volatile and escape characteristics of trimethylamine, diethylamine and triethylamine is effectively improved, the false positive phenomenon can be effectively eliminated through headspace sampling and a multi-reaction monitoring mode, and the method is suitable for large-scale popularization and application. The peak appearance of trimethylamine, diethylamine and triethylamine is completed within 6.5 minutes.

The disclosure relates to a method of producing a multi-metal catalyst film and of producing a reactor system for catalytic removal of a wide variety of contaminants (for example, nitrate, nitrite, perchlorate, chlorate, chromate, selenate, chlorophenols, 2,4-D, dicamba, atrazine, trichloroacetic acid, bromochloroiodomethane, NDMA, TCE, TCA, chloroform, freons, RDX, HMX, TNT, PFOA, and PFOS) from water and wastewater. The disclosure also relates to a method of using the multi-metal catalyst for the removal of such contaminants and a system comprising the multi-metal catalyst film for removing such contaminants.

The invention discloses a method for electrocatalytic hydrogenation dehalogenation of haloacetic acid or halomethane in a water body, which is characterized in that a conductive material of which the surface is modified with ruthenium or platinum is used as a catalytic cathode, water is used as a hydrogen source, and the haloacetic acid or halomethane in the water body is subjected to electrochemical hydrogenation dehalogenation to form acetic acid or methane. The price of precious metal in the catalytic cathode is lower, and the unit price of ruthenium is far lower than that of palladium and rhodium; and compared with a palladium-modified catalytic cathode, the dechlorination selectivity is higher, and the selectivity of hydrodechlorination of trichloroacetic acid into acetic acid in a water body is improved by 11.7%.

The invention belongs to the technical field of biology, and relates to a method for large-scale preparation of high-purity hydrolyzed corac acid or a salt thereof. The method comprises the following steps: 1) adding a solution containing corac acid or a salt thereof into a corac acid degrading enzyme containing an amino acid sequence as shown in SEQ ID NO: 1 or having at least 90% sequence identity with the SEQ ID NO: 1; terminating in the step 2) is achieved through a terminating agent, a boiling water bath and / or an ice bath, the terminating agent is selected from one or more of activated carbon, absolute ethyl alcohol, methyl alcohol, EDTA, trichloroacetic acid and sodium carbonate, and preferably, the activated carbon is used for achieving terminating in the step 2); and further obtaining the hydrolyzed corac acid or the salt thereof. The molecular structure of the hydrolyzed sodium currate prepared by the method provided by the invention has acetylation and pyruvic acid modification, the preparation condition is mild, the production cost is low, continuous production can be realized, and industrial amplification is easy.

The invention relates to a non-noble metal-based paired electro-catalysis method for producing formic acid by coupling cathode dehalogenation with anode formaldehyde oxidation, which realizes efficient dehalogenation removal of pollutants and generation of high-value products. The Co-CuxO nanowire electrode with excellent catalytic performance is synthesized through a simple method and serves as a cathode and an anode at the same time, and the purpose that the cathode removes halogenated pollutants and the anode oxidizes formaldehyde to produce formic acid at the same time is achieved. Co-CuxO promotes generation of H *, the performance of electroreduction dehalogenation is improved, and the removal rate of trichloroacetic acid can reach 92.1% or above. And moreover, the reaction energy barrier is reduced, the selectivity of formic acid generated by oxidizing anode formaldehyde is improved, and the formic acid selectivity and Faraday efficiency can reach 100%. A paired electro-catalysis system shows extremely stable and outstanding electro-catalysis performance in the aspect of converting wastes into value-added products, and the problems of poor anode utilization rate and high energy consumption in the current electro-catalysis dehalogenation reaction are solved.

The invention relates to the technical field of raw malt, and particularly discloses a raw malt extraction method which comprises the following steps: preparing a phosphate buffer solution; preparing a boric acid buffer solution; preparing a derivatization solution by using the prepared boric acid buffer solution; the method comprises the following steps: breaking walls of dried raw malt and crushing into powder by using a multifunctional crusher to obtain raw malt powder, dissolving the raw malt powder in distilled water, and carrying out ultrasonic extraction to obtain a raw malt stock solution; after a trichloroacetic acid solution is added into the raw malt stock solution, the raw malt stock solution is subjected to centrifugal treatment, and supernate is obtained; adding a sodium hydroxide solution into the supernate to enable the pH value of the first mixed solution to be neutral, and adding a phosphate buffer solution into the first mixed solution to obtain a second mixed solution; carrying out sampling derivatization on the second mixed solution and the derivatization solution, and carrying out ultraviolet determination within 2min. By adopting the derivatization-ultraviolet spectrophotometry, the analysis time can be remarkably shortened, the operation complexity and cost can be reduced, and the method is more suitable for daily use in laboratories.

The invention discloses a method for catalytically hydrogenating and dehalogenating haloacetic acid or halomethane in a water body, which comprises the following steps of: catalytically hydrogenating and dehalogenating haloacetic acid or halomethane in the water body into acetic acid or methane by taking a ruthenium or platinum-containing material as a catalyst and hydrogen as a reducing agent; the noble metal in the catalyst is cheaper, and the unit price of ruthenium is far lower than that of palladium and rhodium; according to the method, the dehalogenation selectivity is higher, and compared with a palladium catalyst, the selectivity of hydrodechlorinating trichloroacetic acid in a water body into acetic acid is improved by 10.3%-15.5%; and the selectivity of trichloromethane hydrodechlorination into methane is improved by 8.6%-10.0%.

The invention belongs to the technical field of environmental engineering, and particularly relates to a rapid prediction method for trichloroacetic acid generation potential in a water disinfection process. The rapid prediction method for the trichloroacetic acid generation potential in the water disinfection process comprises the following steps: constructing a training set and a test set which respectively and independently comprise a plurality of organic compounds and trichloroacetic acid generation potential values and key molecular characteristic parameters corresponding to each organic compound; an extreme gradient lifting machine learning algorithm is adopted to construct a trichloroacetic acid generation potential prediction model, and model precision verification is carried out; optimizing by adopting a Bayesian optimization algorithm to obtain a trichloroacetic acid generation potential optimal prediction model; and inputting the key molecular characteristic parameters of the target compound into the optimal prediction model to obtain the trichloroacetic acid generation potential value of the target compound. The rapid prediction method provided by the invention realizes rapid prediction of the TCAAFP value of the organic compound in the chlorine disinfection reaction, and has the advantages of convenient operation, low cost, strong stability and wide application range.

The invention belongs to the technical field of compound preparation, and particularly provides a preparation method of L-glutamic acid-1-tert-butyl ester, which comprises the following steps: step S1, carrying out imidization reaction on an L-glutamic acid-5-methyl ester compound and benzophenone imine to generate N-dibenzylidene-L-glutamic acid-5-methyl ester; step S2, enabling the N-dibenzylidene-L-glutamic acid-5-methyl ester and tertiary butyl-2, 2, 2-trichloroacetic acid imine ester to be subjected to a tert-butyl esterification reaction, so as to generate N-dibenzylidene-L-glutamic acid-5-methyl ester-1-tert-butyl ester, and enabling the N-dibenzylidene-L-glutamic acid-5-methyl ester-1-tert-butyl ester to be subjected to a tert-butyl esterification reaction; and S3, carrying out hydrolysis reaction on the N-dibenzylidene-L-glutamic acid-5-methyl ester-1-tert-butyl ester to remove a methyl ester group, and removing a protecting group on an amino group, so as to generate the L-glutamic acid-1-tert-butyl ester. The preparation method disclosed by the embodiment of the invention is used for preparing the L-glutamic acid-5-methyl ester-1-tert-butyl ester from the N-dibenzylidene-L-glutamic acid-5-methyl ester-1-tert-butyl ester. According to the application, the tertiary butyl-2, 2, 2-trichloroacetic acid imine ester is used for carrying out the tert-butyl esterification reaction, so that the yield is high, the reaction condition is mild, the post-treatment is simple, the control on the generation of glutamic acid, pyroglutamic acid and pyroglutamic acid tert-butyl ester is facilitated, and the impurities are few.

This invention belongs to the field of recycling and purification technology, specifically relating to a method for recovering the β isomer from a CME solution containing both β and α isomers. The method includes the following steps: concentrating the CME solution containing both β and α isomers and dissolving it in methanol with trichloroacetic acid to form a salt, followed by cooling and crystallization and filtration to obtain the trichloroacetic acid salt of the CME β isomer; then, ionizing the trichloroacetic acid salt of the CME β isomer in methanol with ammonia to obtain the CME β isomer. By reacting trichloroacetic acid with the α and β isomers of CME to form a salt, the different solubilities of the trichloroacetic acid salts of the α and β isomers are utilized to separate the trichloroacetic acid salt of the CME β isomer, and then ionizing the trichloroacetic acid salt of the CME β isomer with ammonia, the CME β isomer is recovered.

The invention relates to the technical field of primary processing of natural rubber, in particular to a method capable of controlling the protein content of microbial coagulation natural latex and a mixed coagulation aid. Sulfonic acid has the characteristics of an anionic surfactant, can play a role in permeation and assistance, and can inactivate enzymes generated by microorganisms; sodium hypochlorite is decomposed under an acidic condition to release chlorine, so that microorganisms in latex can be killed; sodium chlorite is similar to sodium hypochlorite and also has the effect of killing microorganisms in latex; the trichloroacetic acid can enter an enzyme protein structure under the auxiliary action of the sulfonic acid, so that the conformation of the enzyme is changed, and the enzyme is inactivated. The mixed solidification auxiliary agent provided by the invention can regulate and control the content of protein in natural rubber, the content of the protein is fixed in a target range, and a natural rubber product with high performance and stable batch is produced.

The invention relates to a method for improving antioxidant activity of pine pollen polysaccharide by utilizing bifidobacterium fermentation, which comprises the following steps: S1, adding bifidobacterium liquid into pine pollen for fermentation to obtain a fermentation product; s2, adjusting the pH value of the fermentation product in the step S1 to be acidic, and adding protease for enzymolysis to obtain an enzymolysis product; s3, carrying out flash extraction on the enzymolysis product obtained in the step S2, and centrifuging to take supernate, so as to obtain a pollen pini crude polysaccharide extracting solution; and S4, adding a trichloroacetic acid solution into the pollen pini crude polysaccharide extracting solution obtained in the step S3, and dialyzing to obtain the pollen pini polysaccharide with improved antioxidant activity. Compared with the prior art, the pine pollen polysaccharide obtained through fermentation of bifidobacteria can obviously improve the antioxidant activity, improve the development and utilization value of pine pollen and improve the application and market competitiveness of the pine pollen polysaccharide in multiple fields compared with the pine pollen polysaccharide obtained through unfermented pine pollen polysaccharide.

The application relates to the technical field of biological detection, and particularly relates to a sample processing liquid and application thereof in ELISA detection of milk and milk products. The sample processing liquid comprises the following components in percentage by weight: 2-3% of ethylenediaminetetraacetic acid disodium salt dihydrate; 0.075-0.125% of trichloroacetic acid; 10-30% of methanol; and the balance is ultrapure water; and the sample is milk and milk products. The sample processing liquid provided by the application can efficiently and conveniently reduce the matrix interference of milk and milk products in ELISA detection, so that the accuracy, precision and recovery rate of detection can be significantly improved.

The invention discloses a high-purity amelogenin extraction process, comprising the following steps: S1. providing a crude extract of enamel matrix protein; S2. adding a trichloroacetic acid solution to the crude extract of enamel matrix protein, shaking and incubating, so that the precipitate is fully precipitated; wherein the concentration of trichloroacetic acid in the crude extract of enamel matrix protein is 1.35%≤c≤1.50%; S3. centrifuging the incubated mixed solution and collecting the supernatant; S4. continuing to add the trichloroacetic acid solution to the collected supernatant, shaking and incubating; after the precipitate is fully precipitated, centrifuging and collecting the precipitate to obtain amelogenin P148. The high-purity amelogenin extraction process provided by the invention has simple steps, good repeatability, high purification efficiency and low cost.

The invention provides a method for simultaneously detecting dichloroacetic acid and trichloroacetic acid in urine, and belongs to the technical field of analysis detection and occupational health / environmental health. According to the method disclosed by the invention, a synergistic pretreatment strategy of acidic sample loading, WAX / reversed-phase mixed mode solid-phase extraction, water / low-proportion organic phase step-by-step leaching and ammonia-water-containing organic phase elution is adopted; a technical route of protein precipitation, acidification pH regulation, purification and enrichment by adopting WAX / reversed-phase mixed mode solid-phase extraction on a 96-well plate and stable isotope internal standard isotope dilution LC-MS / MS quantification is adopted, the method can effectively reduce the matrix effect and realize high-throughput analysis in a high-salinity urine matrix, the quantitation limits of DCEA and TCAA are not higher than 0.30 g / L and 0.20 g / L respectively, and the method has the advantages that the method is simple and convenient to operate, and the method is suitable for large-scale popularization and application. The method is suitable for biological monitoring and risk assessment of occupational and environmental low-level exposure crowds.

The invention relates to the technical field of food detection, discloses an efficient detection method for six sugar alcohol compounds in dairy products, and aims to solve the problems that in the prior art, dairy product protein precipitation and high-efficiency dissolution of strong-polarity sugar alcohol are difficult to consider at the same time, and toxic precipitants, high-temperature treatment or complex solid-phase extraction are often depended on. The problems of tedious operation, high equipment threshold and poor detection stability exist in the prior art, trichloroacetic acid with optimized concentration is used for constructing a water phase system, and dissolution of six sugar alcohols and preliminary precipitation of protein are synchronously realized; the high-protein matrix of the milk powder is supplemented with precise supplementary precipitation, and the liquid milk is simplified; a specific chromatographic column and gradient elution are combined, linear correlation is established by adopting an external standard method, synchronous detection of six sugar alcohols is completed, high-temperature and solid-phase extraction consumables are not needed, two matrixes of milk powder and liquid milk are adapted, the operation time is short, the detection recovery rate is high, the precision is excellent, the existing pain point is effectively solved, and the batch detection requirement of a conventional laboratory is met.

The invention belongs to the technical field of recovery and purification, and particularly relates to a method for recovering a beta isomer from a CME solution containing beta and alpha isomers. The method for recovering the beta-isomer from the CME solution containing the beta-isomer and the alpha-isomer comprises the following steps: concentrating the CME solution containing the beta-isomer and the alpha-isomer, dissolving the concentrated CME solution and trichloroacetic acid in methanol for salt forming reaction, cooling, crystallizing, and filtering to obtain trichloroacetate of the CME beta-isomer; and dissociating the trichloroacetate of the CMEbeta isomer in methanol by using ammonia water to obtain the CMEbeta isomer. According to the method, trichloroacetic acid reacts with an alpha isomer and a beta isomer of CME to form salt, trichloroacetate of the CME beta isomer is separated out by utilizing different dissolvability of trichloroacetate of the alpha isomer and trichloroacetate of the beta isomer, and then trichloroacetate of the CME beta isomer is dissociated by ammonia water, so that the CME beta isomer is recycled.

The invention provides a catalytic cracking propylene yield-increasing auxiliary agent as well as a preparation method and application thereof, and the preparation method of the propylene yield-increasing auxiliary agent comprises the following steps: reacting a ZSM-5 molecular sieve with trichloroacetic acid and tetraethoxysilane in water to obtain a modified intermediate; mixing the modified intermediate with soluble salt of modified metal and melamine in a composite solvent, filtering, taking a solid sample, and roasting to obtain a metal modified molecular sieve; and mixing the metal modified molecular sieve, clay and a binder in water to obtain slurry, carrying out spray drying molding on the slurry to obtain solid particles, and roasting again to obtain the catalytic cracking yield-increasing propylene assistant. After the key component ZSM-5 molecular sieve in the propylene assistant is modified, the propylene assistant has higher mass transfer rate, metal is uniformly deposited on the molecular sieve, the metal utilization rate and the catalytic cracking reaction performance are improved, the propylene yield in a catalytic cracking product is improved, and the coke selectivity is reduced.

The invention discloses a deuterated acetic acid and deuterated acetyl compound high-efficiency electrosynthesis method taking D2O as a deuterium source, and the deuterated acetic acid high-efficiency electrosynthesis method comprises the following steps: in a standard three-electrode double-chamber electrolysis system, taking deuterium water as the deuterium source, adding an electrolyte and a surfactant, and reducing trichloroacetic acid through a constant current electrolysis method to obtain deuterated acetic acid; wherein the monometal electrode for in-situ growth of the nanorod is a working electrode in the standard three electrodes. The method is high in conversion rate and selectivity, is an efficient synthesis method, takes cheap deuterium water as a deuterium source, is mild in reaction condition, does not need high temperature and high pressure, is simple to operate, is easy to separate a product, and can be used repeatedly, and a green, safe and efficient method is provided for synthesis of deuterated acetyl drugs.

The invention relates to the technical field of lipopolysaccharide preparations, in particular to a placenta lipopolysaccharide preparation and a preparation method thereof. Comprising the following components in parts by weight: 90-95 parts of placenta tissue, 1-5 parts of sodium carbonate, 0.1-1 part of trypsin, 0.1-0.5 part of luristatin peptide, 1-2 parts of chloroform, 0.1-1 part of chondroitin sulfate, 5-10 parts of trichloroacetic acid, 70-80 parts of methanol, 0.1-1 part of ascorbic acid and 0.5-1 part of sodium chloride. As the bright inhibition enzyme peptide can inhibit the activity of trypsin, components such as proteins and peptides which have an auxiliary effect on immunoregulation are protected from being damaged, and the quality and the effect of the final preparation are ensured. The chondroitin sulfate is added to form a physical barrier or generate intermolecular interaction with the lipopolysaccharide, so that the exposure of the lipopolysaccharide in a complex chemical environment is reduced, and the structural change or activity loss of the lipopolysaccharide due to the change of the chemical environment is prevented.

The application provides a catalytic cracking propylene-yield catalyst, a preparation method and application thereof, and the preparation method comprises the following steps: reacting ZSM-5 molecular sieve, trichloroacetic acid and tetraethyl orthosilicate in water to obtain a modified intermediate; mixing the modified intermediate, a soluble salt of modified metal and triazemaine in a composite solvent, filtering, taking a solid sample and roasting to obtain a metal-modified molecular sieve; mixing the metal-modified molecular sieve, Y-type molecular sieve, clay and a binder in water to obtain a slurry, spray-drying the slurry to form a solid particle, and roasting again to obtain the catalytic cracking propylene-yield catalyst. After modification of the key component ZSM-5 molecular sieve in the catalyst, the propylene-yield catalyst has a higher mass transfer rate, the metal is uniformly deposited on the molecular sieve, the metal utilization rate and the catalytic cracking reaction performance are improved, the propylene yield in the catalytic cracking product is improved, and the coke selectivity is reduced.

The application relates to an indole derivative obtained by converting quinoline nitrogen-oxide and a synthesis method of the indole derivative, the chemical structural formula of the derivative is shown as formula 2; the synthesis method is as follows: quinoline nitrogen-oxide, dimethyl acetylene dicarboxylate and water are used as reaction raw materials and are added into 1,2-dichloroethane solvent, a first heating stirring reaction is carried out under the catalysis of diphenyl phosphate, after TLC monitoring shows that the conversion of quinoline nitrogen-oxide of formula 1 compound is complete, trichloroacetic acid and molecular sieve dehydrating agent are added, a second heating stirring reaction is carried out, the reaction is monitored until complete through TLC, the solvent is evaporated, and then purification is carried out to obtain the indole derivative. The method has the advantages of high atom economy, mild reaction condition, green, low cost, high conversion rate and the like, meanwhile, the method is a carbon recombination strategy for directly editing a molecular skeleton, can provide a new idea for late-stage design and optimization of a drug molecule, and can accelerate the drug discovery and development process, and has good theoretical value and application prospect.

The present invention provides a blood lead detection method, and the blood lead detection method includes the following steps: (1) Mix a blood sample to be measured, a protease and a buffer solution and perform water bath, then mix with an acid and continue water bath, cool, mix with trichloroacetic acid and centrifuge, take the supernatant and adjust the pH to obtain a test solution; (2) Mix the test solution obtained in step (1) with an aqueous solution of gold nanoclusters, then perform detection using a fluorescence spectrophotometer, and calculate the blood lead concentration in the blood sample to be measured by combining with a standard curve. The blood lead detection method provided by the present invention is simple to operate, has a low detection limit, high sensitivity, and has little limitation on personnel requirements and site and instrument requirements.

The invention relates to a preparation method of a drug intermediate azaspiro [4.5] decane derivative, and belongs to the technical field of drugs and chemistry. The invention provides a preparation method of a drug intermediate azaspiro [4.5] decane derivative shown as a formula 3. The reaction is as follows: # imgabs0 # comprises the following steps: step 1, reacting a compound shown as a formula 1 with a phosphorus reagent in the presence of alkali to obtain a compound shown as a formula 2; and step 2, obtaining a compound shown in a formula 3 from the compound shown in the formula 2 under the action of trichloroacetic acid and a halogenated alkane solvent. The method provided by the invention has the advantages of good selectivity, good reproducibility, short time consumption, economy and high conversion rate, is suitable for industrial production, and thus has good market value and profound practical significance.

The present application belongs to the technical field of recovery and purification, and particularly relates to a method for recovering a β isomer from a CME solution containing a β isomer and an α isomer. The method for recovering a β isomer from a CME solution containing a β isomer and an α isomer of the present application comprises the following steps: concentrating the CME solution containing a β isomer and an α isomer, then dissolving same and trichloroacetic acid in methanol for a salt forming reaction, and after cooling and crystallization, filtering same, so as to obtain a trichloroacetate of the β isomer of CME; and dissociating the trichloroacetate of the β isomer of CME in methanol by using ammonia water, so as to obtain the β isomer of CME. By reacting trichloroacetic acid with the α isomer and β isomer of CME to form a salt, the trichloroacetate of the β isomer of CME is separated out by utilizing the different dissolvability of the trichloroacetate of the α isomer and the trichloroacetate of the β isomer, and the trichloroacetate of the β isomer of CME is then dissociated by using ammonia water, thereby achieving the recovery of the β isomer of CME.

The invention relates to the technical field of biological detection, in particular to sample treatment liquid and application thereof in ELISA (enzyme-linked immunosorbent assay) detection of milk and milk products. The sample treating fluid comprises the following components in percentage by weight: 2-3% of disodium ethylene diamine tetraacetate dihydrate; 0.075 to 0.125% of trichloroacetic acid; 10 to 30% of methanol; and the balance of ultrapure water. The sample is milk and a milk product. The sample treatment liquid provided by the invention can efficiently and conveniently reduce matrix interference of milk and milk products in ELISA detection, so that the detection accuracy, precision and recovery rate can be remarkably improved.

Topical formulations comprising peroxyacids prepared in situ from trichloroacetic acid, dichloroacetic acid, monochloroacetic acid or acetic acid and hydrogen peroxide are useful for promoting hair growth and for preventing hair loss.

According to the present disclosure, a simple and accurate method for quantifying ergothioneine in a sample containing globin protein can be provided. A method for quantifying ergothioneine in a collected sample, comprising: (A) heating the sample; (B) mixing the heated sample with trichloroacetic acid; and (C) subjecting the sample obtained in step (B) to a quantitative operation; A method comprising:

The present invention addresses the problem of providing an albumen hydrolysate that has emulsifiability, emulsion stability and heat coagulability. An albumen hydrolysate obtained by hydrolysis of albumen with a protease, wherein the dry weight of a precipitate formed by adding nine times the amount of 0.4 M trichloroacetic acid (TCA) to the albumen hydrolysate is 60% or more relative to the dry weight of albumen treated in the same manner.

The present invention discloses a method for enriching and separating sulfonamide antibiotics in drinking water or milk, comprising the following steps: sample processing: adding trichloroacetic acid solution to the sample, vortexing and then ultrasonically centrifuging, and collecting the supernatant; magnetic deep eutectic solvent synthesis: stirring choline chloride, phenol and ferric chloride at room temperature to form a magnetic deep eutectic solvent; magnetic deep eutectic solvent / salt two-phase aqueous system: adding the formed magnetic deep eutectic solvent to the supernatant, vortexing and oscillating, adding salt, vortexing and oscillating, to form a magnetic deep eutectic solvent / salt two-phase aqueous system; extraction: placing a magnet at the bottom of the solution to attract magnetic droplets, moving the magnet upward to achieve phase separation of the two-phase aqueous system, accurately measuring the volumes of the upper and lower phases, and using a high performance liquid chromatograph to determine the concentration of sulfonamide antibiotics in the lower inorganic salt phase. This method can efficiently separate and enrich sulfonamide antibiotics, and the selected solvent is non-toxic and pollution-free, providing a new idea for the separation and enrichment of trace sulfonamide antibiotics.