80 results about "Ethyl cinnamate" patented technology

The present Invention relates to a preservative composition comprising:

a mixture of two to ten of well characterized fragrance raw materials with a cosmetic function, of which at least two are selected from: allyl caproate, benzyl acetate, benzaldehyde, dihydrolsojasmonate, ethyl phenethylacetal, ethyl cinnamate, ethyl methyl phenyl glycidate, ethyl vanillin, 2-heptylcyclopentanone, geranyl acetate, heliotropine, cis-hex-3-en-1-ol, ethylene brassylate, nonalactone gamma, camphylcyclohexanol, undecalactone gamma, 2-t-butylcyclohexylacetate, pentyl salicylate, 2-phenylethanol and 2-phenylethyl acetate; and are contained in at least 20% by weight of said mixture;

at least one preservative; and a sequestrant.

The invention discloses a preparation method of traditional Chinese medicine spices for tobaccos. The preparation method includes the following steps: 1), taking tangerine peels, scutellaria baicalensis, radix ophiopogonis, rehmannia, jasmine, semen lepidii, perilaseed and liquorice; continuously extracting 2-4 times by using a solvent, combining extracting solutions, concentrating the extracting solutions into a concentrated solution, recycling volatile oil, and combining the concentrated solution with the volatile oil to obtain a main spice agent; 2), taking vanillin, cananga oil, ethyl cinnamate, leaf alcohol, trichloroacetic acid methyl benzene methyl ester, sandalwood oil, ethanol and propylene glycol, and uniformly mixing to obtain a surface spice agent; 3), uniformly mixing the main spice agent with the surface spice agent to obtain the traditional Chinese medicine spices. The traditional Chinese medicine spices prepared by the method have effect of clearing heat and decreasing internal heat and freeing lung and relieving asthma; after the traditional Chinese medicine spices are added into the tobaccos, aroma quantity, aroma quality and harmony of the tobaccos can be richened and improved, and strength, stimulation and offensive odor can be reduced.

The invention discloses a preparation method of an ozagrel bulk drug. The method comprises the following steps of: bromating methyl ethyl cinnamate serving as a starting material with NBS (B-Bromosuccinimide) to obtain ethyl 4-bromomethylcinnamate; undergoing a condensation reaction on the ethyl 4-bromomethylcinnamate and imidazole to generate ozagrel ethyl ester; hydrolyzing under an alkaline condition; performing acid precipitation to obtain crude ozagrel; and refining to obtain an ozagrel bulk drug. Due to the adoption of the method, a method for refining catalysts, solvents and crude products used in each reaction step is improved, the product yield is high, the product quality is good, the use of toxic reagents and expensive reagents is avoided, little environmental pollution is caused, and the production cost is low. The method is suitable for industrial production, and is an improved and environmentally-friendly method for preparing the ozagrel bulk drug.

The invention belongs to the technical field of medicine and discloses a preparing method of ozagrel. The method includes the following steps: the 4-bromomethyl ethyl cinnamate is obtained via the reaction of 4-methyl ethyl cinnamate and NBS; ozagrel ethyl is obtained via the reaction of 4-bromomethyl ethyl cinnamate and imidazole; then the crude ozagrel is obtained via hydrolyzing the ozagrel ethyl; and the ozagrel is obtained by refining compound solvent. The method provided by the invention has the advantages of high yield and little environmental pollution, and is more suitable for industrial production; a stability experiment on the ozagrel produced via the preparing method shows that the ozagrel is stable in property, is convenient for transportation and storage, and can be used as an injection material.

The present invention relates to a bird repellent, specifically to a bird repellent composition, powder, granules, and a preparation method thereof. The bird repellent composition comprises a bird repellent perfume and the balance of an inorganic filler, water, a slow-release material capsule wall material and auxiliary agents, wherein the bird repellent perfume is three or four materials selected from 2.5-10% of methyl anthranilate, 0.2-1.0% of nerol, 1-5% of ethyl cinnamate, 0.05-0.5% of cinnamic aldehyde and 10-20% of cinnamamide. According to the present invention, water is adopted as a dispersing phase and gelatin and arabic gum are adopted as slow-release carrier capsule wall materials under effects of a plurality of auxiliary agents to prepare bird repellent effective component microcapsules, and then the microcapsules are mixed with an inorganic filler diatomite and calcium carbonate to prepare the bird repellent powder or granules for seed dressing; and the prepared bird repellent powder can be adopted to replace a large number of powder products prepared from pesticide raw materials on the market, and the bird repellent granules has a characteristic of convenient use, and has an advantage of long time efficacy providing compared with other formulations.

The invention discloses a method for preparing quinazoline-2-thioketone. The method comprises the steps of: under the catalysis of silicoamino rate-earth compound [(Me3Si)2N]3Ln(mu-Cl)Li(THF)3s erving as a catalyst; and preparing the quinazoline-2-thioketone by addition reaction of catalytic o-amino ethyl cinnamate and isothiocyanate, wherein Ln represents a triad rate-earth metal ion and is one of lanthanum, neodymium, samarium or ytterbium; (Me3Si)2N represents trimethyl silicoamino; mu- represents a bridged bond; THF represents tetrahydrofuran; the chemical structural formula of the o-amino ethyl cinnamate and isothiocyanate is shown in the specification; and the general formula of the chemical structure of the isothiocyanate is RNCS. In the method, the catalyst is good in chemical selectivity, high in reactivity, mild in reaction condition and in no need of a solvent, and the yield of a target product is high.

The invention discloses an anti-dropping hair growth shampoo and a preparation method thereof. The anti-dropping hair growth shampoo is prepared from, by weight, 80-85 parts of shampoo substrate and 15-20 parts of anti-dropping hair growth lotion, wherein the anti-dropping hair growth lotion is prepared from, by weight, 70-80 parts of fresh ginger-moutan bark extractive lipidosome suspension and 20-30 parts of astragalus membranaceus extractive lipidosome suspension. The anti-dropping hair growth lotion is also prepared from, by weight, 0.01-0.1 part of alpha-cyanogroup-4-p-hydroxyl ethyl cinnamate. The anti-dropping hair growth shampoo has the advantages of having good stability, good detergency, capable of effectively preventing hair loss and inducing and promoting hair growth, having amild formula, having no irritation on scalp, and being suitable for long-term use.

The invention provides blueberry essence for cigarette paper. The blueberry essence is prepared from, by weight, 1-2 parts of blueberry essence and 8-9 parts of blueberry extract, the blueberry essence is prepared by mixing, by mass, 1%-2% of beta-ionone, 1%-2% of alpha-ionone, 5%-10% of hexadecanal, 10%-15% of heliotropin, 3%-5% of ethyl cinnamate, 8%-10% of ethyl butyrate, 8%-10% of benzyl acetate, 3%-5% of sweet orange oil, 1%-3% of amyl acetate, 1%-2% of ethyl hexanoate, 1%-2% of ethyl oenanthate, 1%-3% of citric acid, 3%-5% of ethyl vanillin and 26%-54% of 95% ethyl alcohol. The blueberry extract is extracted through a supercritical extraction process and has aroma components and natural anthocyanin of blueberries. The blueberry essence is added into the cigarette paper, so that cigarettes have obvious blueberry fragrance and meanwhile have the distinctive blue of the blueberries.

The invention discloses a preparation method of Ozagrel sodium. The method comprises the following steps: performing a bromination reaction on ethyl 4-methylcinnamate and N-bromo-succinimide by takingacetonitrile as a solvent under the triggering of azodiisobutyronitrile, so as to obtain ethyl 4-bromomethylcinnamate; performing a condensation cyclization reaction on the ethyl 4-bromomethylcinnamate and imidazole by taking sodium hydroxide as an acid-binding agent and taking tetrahydrofuran as a solvent, so as to obtain imidazole ethyl 4-methylcinnamate; performing alkali hydrolysis on the imidazole ethyl 4-methylcinnamate, so as to obtain the Ozagrel sodium. According to the preparation method, the condensation cyclization reaction is performed by taking the sodium hydroxide as the acid-binding agent and taking the tetrahydrofuran as the solvent, so that the finally obtained product does not contain toxic components, the yield and the purity of the product can be effectively improved,and the content of genotoxic impurities (the ethyl 4-bromomethylcinnamate and ethyl 4-dibromomethylcinnamate) in the product is zero.

The present invention relates to a bird repellent, specifically to a bird repellent composition, a microemulsion, a microcapsule suspending emulsion, and a preparation method thereof. The biological factor-rich perfume comprises three or four materials selected from 10-60% by weight of methyl anthranilate, 5-6% by weight of nerol, 0.5-1.5% by weight of ethyl cinnamate, 0.1-0.2% by weight of cinnamic aldehyde, and 22-28% by weight of cinnamamide. According to the present invention, water is adopted as a dispersing phase and gelatin and arabic gum are adopted as slow-release carrier capsule wall materials under effects of a plurality of auxiliary agents to prepare the bird repellent microemulsion and the bird repellent microcapsule suspending agent. According to the prepared liquid preparation product, birds can be effectively expelled under the premise of no harm on birds, the environmental protection characteristic is provided during use and a production process, and the product belongs to the real biological preparation harmless bird repellent product.

The invention discloses a blueberry essence and a preparation method thereof, and relates to the technical field of essences and fragrances. According to the technical scheme, the blueberry essence comprises the following components in parts by weight: 0.5-83 parts of essence base, 0.5-100 parts of a solvent and 1-10 parts of blueberry extract. The essence base comprises the following components in parts by weight: 0.1-10 parts of vanillin; 0.1-10 parts of raspberry ketone; 0.1-20 parts of ethyl maltol; 0.2-30 parts of ethyl butyrate; 0.001-5 parts of alpha Ionone; 0.001-1 part of cis-3-hexenyl acetate; 0.003-2 parts of linalool; and 0.004-5 parts of ethyl cinnamate. The blueberry essence prepared by adopting the formula disclosed by the invention has the advantages of being close to the flavor of blueberry fruits and highlighting the flavor of blueberry jam.

The invention provides a method for separating P-hydroxyl ethyl cinnamate from raspberry leaves. The method for separating the P-hydroxyl ethyl cinnamate from the raspberry leaves comprises the following steps: heating, rotating and extracting raspberry leaves for 3-5 times with ethyl alcohol water bath at the temperature of 60 DEG C, putting extracting solutions together, and carrying out vacuum concentration, so that extract is obtained; adding water into the extract and dissolving, extracting with ethyl acetate, carrying out silica gel column chromatography separation on extract liquor, carrying out medium pressure column chromatography separation firstly, wherein petroleum ether and ethyl acetate are adopted as eluant, carrying out gradient eluting by adopting the ethyl acetate and methyl alcohol, carrying out a domestic rabbit in vitro bowel movement experiment, and screening out components with strong anti-diarrhea activity; carrying out low pressure silica gel column chromatography separation purification on the components, carrying out gradient eluting on chloroform and methyl alcohol, putting the same components together, then carrying out column chromatography separation on the component, screened out through the domestic rabbit in vitro bowel movement experiment, with the strongest inhibiting effect by adopting an inverse ODS (ozone depleting substance) filler open column, and eluting with methyl alcohol-water, so that the P-hydroxyl ethyl cinnamate compound is obtained. The P-hydroxyl ethyl cinnamate compound is obtained from the raspberry leaves for the first time, has intestinal peristalsis resisting and anti-diarrhea effect and can be used for preparing a new natural anti-diarrhea medicine.

The invention belongs to the technical field of chemical synthesis and in particular relates to a preparation method of a donepezil hydrochloride key intermediate 3,4-dimethoxy phenylpropionic acid. The method comprises the following steps: taking 3,4-dimethoxybenzaldehyde as a raw material to react with ethyl acetate under the action of sodium ethoxide to obtain an intermediate 3,4-dimethoxy ethyl cinnamate; hydrolyzing the 3,4-dimethoxy ethyl cinnamate under an alkaline condition, and carrying out hydrogenation reduction to obtain the 3,4-dimethoxy phenylpropionic acid. The preparation method provided by the invention has the advantages of environmental friendliness, high product purity, high yield and low raw material cost and the like.

The invention discloses an additive capable of removing unhealthy smell in cigarette contact glue, a preparation method and a use method thereof. The additive is obtained after 25 portions of jujube volatile, 1 portion of vanilline, 22 portions of cigarette flavoring agent, 2 portions of phenyl ethyl cinnamate and 50 portions of solvent are evenly mixed. The additive is added to cigarette contact glue by 0.05% of use quantity. Fragrance and materials are added to the cigarette contact glue for the first time. After being applied, the additive obviously enhances the original fragrance of a cigarette and improves unhealthy smell brought by the combustion of the cigarette contact glue. Moreover, the gluing efficiency of the treated cigarette contact glue is not reduced to any degree. The preparation method has the advantages of simpleness, convenience and low cost and can be applied to large-scale industrial production.

The invention discloses a luminous aluminum pigment for a water-based paint and a preparation method of the luminous aluminum pigment. The luminous aluminum pigment is prepared from the following raw materials in parts by weight: 50-70 parts of modified aluminite powder, 2-3 parts of isostearyl glucoside, 10-15 parts of polyvinylpyrrolidone, 3-5 parts of phenylsulfonyl trihydroxymethylaminomethane, 2.5-4.5 parts of betaine salicylate, 2-3 parts of zinc isoocatanoate, 5-10 parts of dibutyl maleate, 60-80 parts of tung oil, 15-25 parts of talcum powder, 5-10 parts of polyethylene micronized wax, 4-8 parts of hydroxypropyl xanthan gum powder, 2-4 parts of pentachlorophenol and 1-3 parts of p-methoxy ethyl cinnamate. The luminous aluminum pigment prepared by the method has excellent water resistance, weather fastness and acid and alkali resistance, is easily dispersed in a water-based paint, is easily dissolved together with a water-based paint system, is wide in application range, and has a wide application prospect.

The invention relates to the field of chemical synthesis, particularly relating to a preparation method for the ethyl cinnamate derivatives. The preparation method of the invention is that the malonate diethylester reacts with the potassium hydroxide in the solution to produce the potassium salt of the malonate single-diethyl ester.The ice acetic acid is added to produce the malonate single-diethyl ester; the malonate single-diethyl ester then does the condensation reaction with the cinnamate with the catalysis of the amino acid. The preparation method of the invention is cheap and easy in the obtainment of the raw materials, simple in the operation, and low in the cost.

The invention provides cinnamon aroma type essence for cigars as well as a preparation method and an application of the essence. The cinnamon aroma type essence for the cigars is prepared from 2-10 parts of 2-methoxycinnamaldehyde, 2-10 parts of 4-methoxycinnamaldehyde, 2-10 parts of ethyl cinnamate, 10-30 parts of a plum extract, 0.5-5 parts of dihydrocoumarin, 15-30 parts of propylene glycol and 15-65 parts of ethyl alcohol by mixing, leaving to stand and filtration of sediment with a filter membrane. The essence is diluted with 70% ethyl alcohol and directly sprayed on cut tobaccos of the cigars, the cut tobaccos are taken after being placed for 4 h, and the cigars are produced. The essence can effectively enrich the aroma of the cigars, endow the cigars with characteristic cinnamon aroma, increase the cinnamon sweet aroma specific to the cigars and improve the smoking comfort of the cigars.

The invention discloses a heat-resistant low-smoke flame-retardant PVC cable. The cable consists of aluminum alloy cable cores, a filling layer, an ethylene-propylene rubber insulating layer, a heat-resistant low-smoke-resistant PVC protective jacket and nickel cable cores, wherein the three aluminum alloy cable cores and the three nickel cable cores are extruded in the filling layer; the ethylene-propylene rubber insulating layer is extruded on the outside of the filling layer; and the heat-resistant and low-smoke-resistant PVC protective jacket is extruded on the outside of the ethylene-propylene rubber insulating layer. Raw materials comprise PVC resin, styrene, 3-(2-furyl) acrylic acid, ethyl cinnamate, trioctyl trimellitate, epoxidized soybean oil, calcium carbonate, a calcium-zinc composite stabilizer, dimethyl sulfoxide, triphenyl phosphate, dimethylacetal and the like. The heat-resistant low-smoke flame-retardant PVC cable has excellent heat deformation resistance and heat ageing resistance, is good in consistency and anti-cracking property, and has good softness; the problem of hot stress cracking is avoided; the heat-resistant low-smoke flame-retardant PVC cable has goodextruding processability, mobility, stretching strength and tensile elongation, process consumption can be reduced, and the manufacturing cost is reduced.

The invention provides a sweet citrus type flavoring agent for a shed cattle feed and a preparation method of the sweet citrus type flavoring agent, and belongs to the technical field of feed additives. The flavoring agent comprises 10-18 parts of linalool, 5-10 parts of linalyl acetate, 60-100 parts of citral, 1-3 parts of octanal, 5-10 parts of phenylacetic acid, 10-20 parts of phenethyl alcohol, 1-5 parts of ethyl phenylacetate, 1-3 parts of phenyl ethyl cinnamate, 2-5 parts of geraniol, 8-12 parts of limonene, 1-5 parts of sweet orange oil, 60-120 parts of solvents and 200-1000 parts of carriers. A conventional feed flavoring agent still has the problem that the preference flavor of animals cannot be met, peculiar smell in the feed can only be concealed to a certain extent, the stability is low, after the flavoring agent is added to the feed, the quality of the feed is instable, and the palatability is poor. The cattle has keen sense of smell and has obvious perception on differences of the fragrance of the feed, so that the phenomena that the cattle refuses to eat the feed or the food consumption is reduced, can be caused. The sweet citrus type flavoring agent for the shed cattle feed provided by the invention is high in stability and good in palatability, the preference of shed cattle is met, and the effects of guaranteeing stable quality of the feed and inducing the cattle to eat the feed continuously can be achieved.

The present invention is directed to litter compositions including a litter substrate and at least one cinnamic or rosmarinic compound disposed on or within the litter substrate which inhibits odor formation. Examples of cinnamic and/or rosmarinic compounds that have been shown to inhibit odor formation include trans-cinnamic acid, cinnamaldehyde, p-coumaric acid, sinapic acid, caffeic acid, hydrocinnamic acid, rosmarinic acid, ursolic acid, carnosic acid, and ferulic acid. The compositions may be free of ethyl cinnamate, and may include a borate, or be free of borates.

The invention discloses a preparation method and application of an organic basic catalyst for catalytic synthesis of alpha-cyanoethyl cinnamate. The prepared catalyst mPMF can efficiently catalyze benzaldehyde and ethyl cyanoacetate to generate alpha-cyanoethyl cinnamate under mild experimental conditions, and the catalyst has good selectivity on the alpha-cyanoethyl cinnamate and has good stability in a reaction system. The catalyst mPMF is prepared by taking melamine and paraformaldehyde which are commonly used in laboratories and industries as precursors through a solvothermal method, the raw materials are cheap and easy to obtain, the preparation method is simple and easy to operate, and the catalyst mPMF can be used for industrial large-scale production.