131 results about "Dust mites" patented technology

The utility model discloses an acarus killing instrument, which comprises a main body, a dust collector, a dust collector, a dust collector, a dust collector, a dust collector, a dust collector, a dust collector and a dust collector, and is characterized in that a stirrer chamber is limited by the main body and is provided with a suction inlet and an exhaust port; the stirrer element is arranged in the stirrer chamber; the dust collection cup is detachably arranged above the main body, and the dust collection cup is communicated with the exhaust port; the suction motor is arranged in the main body and is positioned behind the stirrer chamber, and the suction motor is communicated with the dust collection cup; wherein the suction motor is a brushless motor. Therefore, by arranging the dust mite removing instrument, dust mites can be efficiently and continuously sucked through the brushless motor, and the running smoothness and accuracy of the suction work can be improved.

The invention provides a full-human anti-Der p1 full-molecule IgG antibody and application thereof, and relates to the field of biological pharmacy. The full-human anti-Der p1 full-molecule IgG antibody comprises a light chain variable region and a heavy chain variable region, the amino acid sequences of the antigen complementary determining regions CDR of the light chain variable region are respectively as shown in SEQ ID NO.15, SEQ ID NO.16 and SEQ ID NO.17; the amino acid sequences of the antigen complementary determining region CDR of the heavy chain variable region are respectively shown as SEQ ID NO. 18, SEQ ID NO. 19 and SEQ ID NO. 20. The full-human anti-Der p1 full-molecule IgG antibody provides high specificity, high affinity, low immunogenicity and potential immunomodulatory function through the specific CDR design, and can provide a new treatment and diagnosis means for allergic diseases caused by dust mites.

To provide a mite repellent composition having an excellent mite repellent effect against house dust mites even after a long time has elapsed and also having excellent safety for humans and animals.SOLUTION: A mite repellent composition contains: (a) 1,8-cineol and / or 1,4-cineol; and (b) a perfume component, wherein the perfume component includes one or more kinds of perfume compounds having a logP value of 2.0 to 5.5. A blending ratio (a / b) of the component (a) to the perfume compound contained in component (b) is set to 5 to 100 on a mass basis. The perfume compound contained in the component (b) is at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclodecenyl propionate, benzyl salicylate, limonene, and amyl salicylate.SELECTED DRAWING: None

The invention relates to the technical field of allergy detection, in particular to an inhalation allergen specific IgE antibody detection kit and application thereof. The kit is a colloidal gold detection kit. The detection objects are pollen, dust mites and animal scurf; the kit comprises a colloidal gold labeled mouse anti-human IgE antibody arranged on a test strip combination pad; the pollen antigens (Art v1, Amb a1 and Bet v2), the dust mite antigens (Der f1 and Der p1) and the animal scurf antigen (Can f1) are arranged on a nitrocellulose membrane of the test strip. The kit provided by the invention can be used for rapidly identifying the allergen of the inhalation allergy symptom and classifying the severity of the allergy symptom, and the identification result has relatively high accuracy.

The invention relates to the field of antibodies, in particular to an anti-Der p 1 antibody and application thereof. The invention provides an anti-Der p 1 antibody, the anti-Der p 1 antibody comprises a heavy chain variable region and a light chain variable region, the heavy chain variable region comprises an amino acid sequence of a complementarity determining region, and the amino acid sequence of the complementarity determining region comprises CDR1 as shown in SEQ ID No.1, CDR2 as shown in SEQ ID No.2 and CDR3 as shown in SEQ ID No.3; or the amino acid sequence of the heavy chain variable region is as shown in SEQ ID No.8. The anti-Der p1 antibody provided by the invention is a monoclonal antibody with high affinity and high sensitivity, after the monoclonal antibody is subjected to humanized IgE transformation, the monoclonal antibody is applied to a Dermatophagoides pteronyssinus allergen component Derp1 specificity IgE magnetic particle chemiluminescence quantitative detection reagent, and a standard curve independently calibrated by the Dermatophagoides pteronyssinus allergen component Derp1 can be obtained; real, accurate and repeatable absolute quantification is realized, the Dermatophagoides pteronyssinus allergen component Derp 1 specificity IgE with the concentration of 0.1 IU / mL can be detected, and the method has clinical diagnosis significance in allergic reaction identification.

The invention relates to the field of fiber technology, and in particular to a method for preparing an antibacterial and anti-mite intelligent constant temperature fiber, comprising the steps of preparing a soybean protein solution, preparing a temperature regulating solution, preparing a mixed spinning solution, pre-spinning injection, spinning and post-processing. The antibacterial and anti-mite intelligent constant temperature fiber prepared by the invention has better softness and hand feel than the same type of added functional fibers in the industry due to the addition of soybean protein isolate, and has obvious advantages. The melting enthalpy is 44.5-55.6 J / g, the crystallization enthalpy is 42.4-53.1 J / g, and the fiber has better constant temperature performance. The fiber has an antibacterial rate of more than 98% against Staphylococcus aureus, more than 94% against Escherichia coli, and more than 95% against Candida albicans, and has a very strong anti-mite effect, with a detection rate of 0 dust mites and an avoidance rate of ≥99%.

1. Name of the Design Product: Dust Mite Remover (C22). 2. Use of the Design Product: For daily cleaning, dust mite removal, and vacuuming. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Illustrates the Design Key Points: 3D View 1 of Design 1. 5. Design 1 is designated as the basic design. 6. Other Situations Requiring Explanation Other Explanation: Part A is made of transparent material.

This invention discloses a method, system, equipment, and medium for real-time detection of the overall performance of a mite remover, specifically relating to the field of performance testing technology. The method includes sealing and connecting the mite remover under test with a test sample chamber containing a built-in standard dust mite test sample block; continuously acquiring instantaneous input power and instantaneous wind speed through a power acquisition unit and a hot-wire anemometer, and calculating the instantaneous intake flow rate based on the cross-sectional area of ​​the duct; continuously acquiring a sequence of microscopic images of the upper surface of the fiber fabric layer within a set detection period; extracting individual dust mite displacement events using the inter-frame difference method, counting the total number of events, and calculating the average displacement velocity value; and using the average intake power, the total number of individual dust mite displacement events, and the average displacement velocity value as input variables, generating a comprehensive evaluation value of the overall machine's performance through a performance judgment model. This invention integrates power, flow rate, and the dynamic response parameters of live dust mites, achieving real-time and accurate quantitative evaluation of the overall performance of the mite remover.

The invention discloses a construction method and application of a machin allergic rhinitis animal model, and belongs to the field of disease animal model construction. According to the method, house dust mites are firstly used for sensitization, then 10% hydrogen peroxide and house dust mites are combined for excitation modeling, the 10% hydrogen peroxide destroys nasal mucosa and accelerates occurrence of allergic rhinitis, and the monkeys with allergic rhinitis are obtained after 13 periods of modeling. According to the method, the animal model which is highly similar to human allergic rhinitis in behavior, inflammatory symptom and phenotype is successfully constructed. The model provides guarantee for observing nasal symptoms and rhinitis behaviors of allergic rhinitis, inducing an organism to generate allergy-related immune response, establishing a sensitization basis, simulating a pathogenesis process, researching pathogenesis of allergic rhinitis, screening allergic rhinitis drugs and the like.

1. Name of the Design Product: Wireless Dust Mite Remover (FZ-288). 2. Use of the Design Product: A dust mite remover for household cleaning. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Illustrates the Design Key Points: Perspective view.

The application relates to a dust removal structure and a cleaning device, which comprises a shell and a brush head assembly. The shell has a receiving space and an opening communicating with the receiving space. The brush head assembly is arranged in the receiving space and rotationally connected with the shell. The brush head assembly can rotate around the axial direction of the receiving space, and at least part of the brush head assembly extends out of the receiving space through the opening and is arranged to intersect the plane of the opening in the axial direction. The brush head assembly has a guide channel extending in the axial direction of the receiving space. The shell also has a dust suction port. The dust suction port and the opening are located at the two ends of the axial direction of the receiving space. The guide channel is configured to guide the medium on the side of the opening to the dust suction port when the brush head assembly rotates. In this way, the brush head assembly pushes the medium, such as dust and dust mites, on the surface to be cleaned to the side of the dust suction port far away from the opening, so that dust suction can be facilitated, and the dust removal efficiency is improved.

The invention relates to the technical field of biology, in particular to an engineering strain for expressing dermatophagoides pteronyssinus allergen derived protein and application of the engineering strain. The invention provides engineering bacteria such as ECDer1, ECDer2, SEAgr-Der1, SEAgr-Der2 and the like by adopting an authenticated probiotic chassis strain, and the engineering bacteria are used for safely and effectively treating the allergic diseases, particularly allergic skin diseases mediated by dust mite related inhalation allergens and respiratory tract allergic diseases.

The invention discloses a construction method of an animal model for combined induction and exacerbation of asthma. The method comprises the following steps: injecting ovalbumin or dermatophagoides pteronyssinus extract into an intraperitoneal cavity for sensitization; aerosol inhalation of allergen is carried out for airway re-exposure; in the aggravating stage, pathogenic microorganisms such as pseudomonas aeruginosa, aspergillus fumigatus or respiratory syncytial virus are given and exposed to 500 mu g / m PM2.5 aerosol; lung tissue and bronchoalveolar lavage fluid are then detected. The established model shows that the airway resistance is obviously enhanced and persistent, the mucous thrombus formation rate is greater than 50%, the smooth muscle is obviously thickened, and the model is accompanied by eosinophilic granulocyte and neutrophil infiltration and high expression of various inflammatory factors. The model is good in stability and high in repeatability, can truly simulate clinical asthma acute exacerbation and steroid insensitive characteristics, and provides a platform for asthma mechanism research and new drug screening.

1. Name of the Design Product: Dust Mite Remover. 2. Use of the Design Product: For removing dust mites. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photo Most Indicating the Design Key Points: Perspective View 1. 5. Other Situations Requiring Explanation: Other Explanation: Part A in Perspective View 1 of this application is a transparent part.

1. Name of the design product: Dust mite vacuum cleaner (DE22). 2. Use of the design product: Used for removing dust mites from clothes. 3. Design key points of the design product: Lies in the shape. 4. Picture or photo that best shows the design key points: Perspective view 1.

The invention relates to the field of allergen detection, in particular to an anti-Der p 2 antibody and application thereof. The invention provides an anti-Der p 2 antibody. A heavy chain variable region of the anti-Der p 2 antibody comprises an amino acid sequence of a complementarity determining region: CDR1 as shown in SEQ ID No.1, CDR2 as shown in SEQ ID No.2, and CDR3 as shown in SEQ ID No.3; or the amino acid sequence of the heavy chain variable region is as shown in SEQ ID No.8. According to the protein, a New Zealand rabbit is immunized by utilizing Der p 2 protein of a main allergen of Dermatophagoides pteronyssinus, and a group of monoclonal antibodies with high affinity and high sensitivity to Der p 2 are obtained through screening. The antibody is further subjected to humanized IgE modification and is applied to a magnetic particle chemiluminescence quantitative detection reagent of Der p 2 specific IgE. According to the reagent, a standard curve for Der p 2 independent calibration can be established, so that accurate and repeatable absolute quantitative analysis is realized, and the detection sensitivity can reach 0.1 IU / mL. The detection method formed on the basis of the anti-Der p 2 antibody provided by the invention has important value for clinical diagnosis of anaphylactic reaction.

The broken lines show the portions of the rolling brush for dust mite vacuum cleaner that form no part of the claimed design.

The present invention relates to an anti-allergic gel for nose containing sodium hyaluronate and a preparation method thereof. The product is composed of paraffin, vaseline, lanolin and sodium hyaluronate. The gel of the present invention is used to relieve seasonal or perennial inhalable allergic rhinitis and dry nose symptoms, such as pollen, dust and dust mites. The product is easy to carry and easy to use, and no preservatives are added in the ingredients, so it is highly safe.

1. Name of the Design Product: Dust Mite Removal Lamp. 2. Use of the Design Product: For lighting, repelling mosquitoes and removing dust mites. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photo that Best Illustrates the Design Key Points: Perspective View 1.

The invention discloses an application of an allergen Blo t 24 in detection of dust mite allergen components. The invention finds that the positive rate of the allergen Blo t 24 is equivalent to that of the allergen Blo t 5 in newly identified allergens, so that the Blo t 24 can be used for detecting allergen components, and the positive rate is as high as 91.36% when a combination formed by the allergens Blo 5, Blo t 21, Blo t 24 and Blo t 2 is used for detecting the allergen components.

To provide a decorative sheet having an allergen reducing performance exhibiting an allergen reducing effect to mite and cedar, while maintaining surface performance of a surface protective layer.SOLUTION: A decorative sheet comprises a crosslink-cured resin layer on the outermost surface. (1) The crosslink-cured resin layer contains a cured product of a crosslink-cured resin and an allergen-reducing agent. (2) The allergen-reducing agent is an allergen-reducing agent having an allergen-reducing performance on mites and cedar, contains a carboxylic acid derivative and a styrene polymer derivative, and contains all of triethylamine, N,N-dimethylallylamine, dimethylpyrrole, tetramethyl-1,3-propanediamine, and N,N,2,2-tetramethyl-1,3-propanediamine as components of at least the carboxylic acid derivative. (3) The crosslink-cured resin layer further contains two different types of fine particles.SELECTED DRAWING: None

The invention relates to a method for obtaining a probiotic product for neutralizing allergens, released by house dust mites, product composition and method of use, which is from the technical field of providing a healthy microclimate based on a probiotic product. The product concerns the maintenance of household stuff in immediate and direct use by humans, such as shoes, blankets, upholstered furniture, clothes, carpets and mats, the air in domestic and office premises, as well as in bathrooms, toilets and vehicles. The product composition consists of a spore concentrate, containing minimum of 1x109 CFU / ml fermentation bacteria class 1 (one), ethanol, hypoallergenic perfume mixture, preservative and water, softened, processed by reverse osmosis and cavitation, ultra-filtered, and microbiologically clean in terms of bacteria and viruses.

The invention relates to the technical field of washing equipment, and provides washing equipment and a control method and device thereof and a storage medium, the washing equipment is provided with a heating device, the heating device is connected with a washing drum of the washing equipment through a drying air duct, and the control method comprises the steps that in response to a preset washing instruction, the heating device is started to heat air; introducing heated air into the drying air duct, and heating the washing drum to a first preset temperature; executing a preset degerming program for degerming; controlling the washing drum to be cooled to a second preset temperature; controlling a water inlet assembly to feed water into the washing drum so as to wet the to-be-washed objects; and executing a preset washing program for washing. Before washing, the temperature is rapidly increased to the preset sterilization temperature through the heating device and kept for a period of time, bacteria and dust mites are effectively killed, then the plush toys are cooled to the proper temperature and washed with water, and the sterilization effect on the plush toys is improved.

The application relates to the technical field of allergy detection, in particular to an inhaled allergen specific IgE antibody detection kit and application thereof. The kit is a colloidal gold detection kit; the detection object is pollen, dust mites and animal dander; the kit comprises colloidal gold labeled mouse anti-human lgE antibodies arranged on a test strip combination pad; and pollen antigens (Art v1, Amb a1, Bet v2), dust mite antigens (Der f1, Der p1) and animal dander antigens (Can f1) arranged on a test strip nitrocellulose membrane. The kit provided by the application can quickly identify the allergen of inhaled allergic symptoms, classify the severity of allergic symptoms, and the identification result has a high accuracy.

The invention belongs to the field of biotechnology and fermentation engineering, and creates a group of probiotic flora by utilizing the mutual growth, symbiosis and antagonism of the probiotic flora. The probiotic group is composed of bacillus amyloliquefaciens (YR003, the preservation number of which is CGMCC (China General Microbiological Culture Collection Center) NO.32698), bacillus subtilis (YR002, the preservation number of which is CGMCC NO.32697), and bacillus siamensis (YR001, the preservation number of which is CGMCC NO.32696). The content ratio of bacillus amyloliquefaciens to bacillus subtilis to bacillus siamensis in the flora is 5: 3: 2. The flora can effectively degrade plant pollen allergen, pet allergen, dust mite allergen and insect excrement allergen and effectively inhibit mycospore allergen. Specifically, poplar pollen allergen, willow pollen allergen, phoenix tree pollen allergen, cypress pollen allergen, cat allergen, dog allergen, house dust mite allergen, dermatophagoides farinae allergen and cockroach allergen are effectively degraded; penicillium allergen, black mould allergen, cladosporium allergen and aspergillus allergen are effectively inhibited.

The invention relates to a method for obtaining a probiotic product for neutralizing allergens, released by house dust mites, product composition and method of use, which is from the technical field of providing a healthy microclimate based on a probiotic product. The product concerns the maintenance of household stuff in immediate and direct use by humans, such as shoes, blankets, upholstered furniture, clothes, carpets and mats, the air in domestic and office premises, as well as in bathrooms, toilets and vehicles. The product composition consists of a spore concentrate, containing minimum of 1x109 CFU / ml fermentation bacteria class 1 (one), ethanol, hypoallergenic perfume mixture, preservative and water, softened, processed by reverse osmosis and cavitation, ultra-filtered, and microbiologically clean in terms of bacteria and viruses.

The utility model discloses a filtering device with multiple filtering layers for an FFU fan, and relates to the technical field of filtering devices. The fan comprises a fan body, an air inlet cavity is fixedly connected to the top face of the fan body, a filter cavity is formed in the fan body, a first filter element and a second filter element are arranged in the filter cavity, plugging assemblies are arranged in the filter cavity and located on the upper sides and the lower sides of the first filter element and the second filter element, and each plugging assembly comprises a sealing disc. Wherein one sealing disc corresponds to and is matched with a cavity opening of the air inlet cavity, the other sealing disc corresponds to and is matched with the air outlet end of the fan body, and an ozone generator is arranged on the upper portion of the inner side wall of the filtering cavity. According to the air purifier, tiny particles such as bacteria, viruses and dust mites in air can be filtered out, the bacteria on the first filter element and the second filter element can be killed, and the cleanliness of the filtered air is prevented from being affected.

The invention discloses a dermatophagoides pteronyssinus allergen Der p 1 recombinant protein, a preparation method, a kit and application, relates to the technical field of biology, and solves the technical problem that a detection result is not accurate enough when a crude extract is used for allergen detection. The method comprises the following steps: designing a pair of specific primers for amplifying Der p 1, carrying out amplification through PCR (Polymerase Chain Reaction), recovering a target band, connecting the target band with a cloning vector, converting to competent cell culture, extracting to obtain a recombinant plasmid containing a target gene, cloning the recombinant plasmid to a prokaryotic expression vector to obtain an expression vector containing the target gene, and carrying out high-throughput screening on the expression vector containing the target gene. The method comprises the following steps: transforming an expression vector containing a target gene into a host cell, inducing expression, and purifying to obtain Der p 1 recombinant protein with an amino acid sequence as shown in SEQ ID NO.1; the recombinant protein is high in biological activity, can be applied to preparation of a magnetic particle chemiluminescence detection kit, and is high in detection accuracy and good in kit stability.

A mite killing instrument comprises an assembling shell with a handle piece, a motor shell arranged at one end of the assembling shell and provided with a driving motor, a dust box detachably connected to the assembling shell and provided with a filtering device, a rolling brush box arranged at the bottom of the assembling shell, and a first air channel arranged between the rolling brush box and the assembling shell. Wherein the dust box and the motor shell communicate with each other and are symmetrically arranged on the assembly shell with the handle piece as the center, the dust box is perpendicularly arranged on the plane where the assembly shell is located, the first air channel communicates with an inner cavity of the rolling brush box and an inner cavity of the dust box, and the driving motor generates negative pressure so that dust mites can enter the dust box through the rolling brush box; according to the utility model, the dust box and the motor shell are symmetrically arranged, so that the dust collection efficiency is ensured, the balance weight of the acarus killing instrument is more balanced, and a user can use the acarus killing instrument conveniently.

The invention discloses portable equipment for improving and preventing rhinitis with small-particle-size negative ions and a use method, and relates to the technical field of rhinitis prevention, the portable equipment comprises a product front shell, the equipment can release small-particle-size and high-activity negative ions by selecting an ecological negative ion generation chip technology, and the negative ions enter the nasal cavity through breathing and act on blood capillaries and nerve endings, so that the rhinitis is improved and prevented. The traditional Chinese medicine composition can regulate vasomotor, improve nasal cavity blood circulation, relieve mucous membrane hyperemia and swelling and relieve nasal obstruction, has the mucous membrane repairing function, promotes nasal mucous membrane epithelial cell regeneration, recovers ciliary movement and secretion functions, enhances the self-cleaning capacity of the nasal cavity, and can regulate whole body immunity, reduce the sensitivity of nerves to mechanical stimulation and reduce anaphylactic reactions such as sneezing. The medicine can activate the reticuloendothelial system, enhance the disease resistance of the organism, reduce rhinitis recurrence and remove environmental allergens, small-particle-size negative ions can adsorb and settle allergens such as dust mites and pollen in air, nasal cavity stimulation is reduced from the source, and double barriers for treatment and prevention are formed.