127 results about "Penicillium" patented technology

The embodiment of the invention discloses a Yarrowia guilliermondii as well as a separation and screening method, an identification method and application of the Yarrowia guilliermondii. The preservation number of the Yarrowia guilliermondii is CGMCC (China General Microbiological Culture Collection Center) No.27603, and the preservation number of the Yarrowia guilliermondii is CGMCC No.27603. The Yarrowia guilliermondii disclosed by the embodiment of the invention has a very good prevention and control effect on postharvest diseases of fruits, and the prevention and control effect of the Yarrowia guilliermondii on the diseases can be enhanced by respectively adding auxiliary factors, namely calcium chloride, alginate oligosaccharide (AOS), phytic acid (PA) and metschhia yeast. Through identification, the antagonistic bacterium is a Yeyrozyma guilliermondii, and the antagonistic bacterium is a Yeyrozyma guilliermondii. The M.guilliermonii has a good control effect on gray mold, penicilliosis, black spot and aspergillus niger of strawberry, apple, pear and tomato fruits, can be rapidly colonized on fruit wounds, and can enhance the resistance-related enzyme activity of the fruits, occupy the wound space and induce the fruit resistance to reduce the morbidity of diseases.

The invention belongs to the field of microorganisms, and discloses bacillus velezensis and application thereof in prevention and treatment of plant fungal diseases. The bacillus velezensis disclosed by the invention is bacillus velezensis YC46, is preserved in the China General Microbiological Culture Collection Center (CGMCC), and has the preservation number of CGMCC No.33975. The bacillus velezensis can grow by taking leftovers in an aquatic product processing process as a unique nutrient source, and has the advantages of high yield, low cost and the like. The bacillus subtilis has the antibacterial activity on plant pathogenic fungi such as fusarium oxysporum, botrytis cinerea, alternaria alternata, colletotrichum gloeosporioides and penicillium, thalli or fermentation products of the thalli can be used as active ingredients for preparing biocontrol microbial agents or bacteriostatic agents for preventing and treating plant fungal diseases, and the bacillus subtilis has good application value and ecological environmental protection value.

The invention relates to the technical field of microorganisms, and discloses a plant lactobacillus capable of inhibiting growth of monascus and application of the plant lactobacillus. The preservation number of the plant lactobacillus is CGMCC (China General Microbiological Culture Collection Center) No.34851. According to the present invention, the plant lactobacillus CCNH295 has strong bacterial inhibition ability on common soybean meal contaminating molds, such as aspergillus flavus, aspergillus ochraceus, fusarium moniliforme and penicillium; the plant lactobacillus CCNH295 has excellent bacteriostatic ability to monascus, and when the plant lactobacillus CCNH295 is used for fermentation production of soybean meal, growth of monascus can be remarkably inhibited, so that mildewing of the fermented soybean meal is effectively inhibited, and the prepared fermented soybean meal does not mildew after being placed at 37 DEG C for 6 months; besides, the fermented soybean meal produced by solid state fermentation of the plant lactobacillus CCNH295 is used as a feed raw material, so that the stability of the feed can be improved, and the palatability of the feed can be improved.

The application discloses a marine source penicillium and a fermentation method and application thereof. The marine source penicillium is named Penicillium sp. DSF059, and the preservation number is CCTCC NO: M 20232310. Penicilliu The application optimizes the culture condition of the strain, selects a culture medium and culture condition with high yield of antibacterial active compounds to carry out fermentation, so that more target products can be obtained, the operation is simple, the cost is low, and meanwhile, the marine source penicillium Penicilliu Penicillium sp. DSF059 can provide an excellent strain for new drug development of resisting plant pathogenic fungi such as coffee leaf blight, coffee brown spot disease, grape gray mold disease, Chinese cinnamon brown spot disease, citrus black rot disease, pepper late blight, hickory leaf blight, coffee black spot disease and four pathogenic fungi separated from coffee leaf diseases and Staphylococcus aureus, and has a good application prospect for preventing and treating the plant pathogenic fungi and Staphylococcus aureus.

The invention discloses a method for converting phosphorus in bone black into soluble phosphorus by adopting penicillium desert, and belongs to the technical field of waste conversion and utilization. According to the method, the indissolvable phosphorus in the bone black is efficiently and stably converted into the soluble phosphorus by utilizing the specifically preserved Penicillium desertorum, the phosphorus dissolving amount within 10 days is up to 2187.50 mg / L, the process is environment-friendly, the raw material adaptability is high, and a feasible microbial conversion way is provided for high-valued utilization of bone black phosphorus resources.

The invention discloses a microbial composition for preventing and treating vomitoxin as well as a preparation method and application of the microbial composition. The microbial composition for preventing and treating vomitoxin is mainly prepared by mixing a component I and a component II according to a mass ratio of (50.0-0.1): (50.0-99.9), the component I comprises trichoderma harzianum powder, trichoderma asperellum powder and penicillium bayi powder; and the component II comprises potassium phosphite, alkene potassium phosphate and potassium tripolyphosphate. The preparation method comprises the following steps: adding the component I and the component II into a stirrer, and stirring and mixing to obtain the coating. The invention also discloses an application of the microbial composition for preventing and treating vomitoxin. The microbial composition disclosed by the invention can generate metabolites with a biocontrol effect, has efficient inhibitory activity on fusarium, can reduce generation of vomitoxin, can effectively regulate diversity of soil microorganisms, realizes crop yield increase and soil improvement, and is green and environment-friendly. The method and application are simple, the cost is low, and the method is suitable for agricultural application.

The embodiment of the invention discloses yarrowia caribeckii as well as a separation and screening method, an identification method and application of the yarrowia caribeckii. The preservation number of the yarrowia caribica is CGMCC (China General Microbiological Culture Collection Center) No.27604, and the preservation number of the yarrowia caribica is CGMCC No.27604. The Caribik Yarrowia spp. Provided by the embodiment of the invention has a good antagonistic effect on gray mold, penicilliosis, black spot and aspergillus niger after fruits are picked, and can obviously reduce the disease morbidity of the fruits of strawberries, apples, tomatoes and pears. And the antagonistic bacterium is identified to be Meyerozyma caribbica, and the antagonistic bacterium can be used as the Meyerozyma caribbica. By respectively adding auxiliary factors, namely calcium chloride, alginate oligosaccharide (AOS), phytic acid (PA) and metschhia pastoris, the disease prevention and control effects of Meyerozyma caribbica can be enhanced. The disease prevention and control effects of the Meyerozyma caribbica can be enhanced by adding the auxiliary factors of calcium chloride, alginate oligosaccharide (AOS), phytic acid (PA) and metschhia pastoris.

The invention discloses a strain of Lysinibacillus bacilli B1 and application thereof, and belongs to the technical field of microorganisms. The preservation number of the bacstein lysine bacillus B1 is GDMCC No: 66653, and the preservation number of the bacstein lysine bacillus B1 is GDMCC No: 66653. The bacstein lysine bacillus has an inhibition effect on penicillium expansum, aspergillus ochraceus, botrytis cinerea, escherichia coli, listeria monocytogenes, sclerotium rolfsii, root rot bacteria, ralstonia solanacearum and fusarium oxysporum. The strain can be used for preventing and treating southern blight and root rot of siraitia grosvenorii, banana fusarium wilt, mycosis of navel oranges and the like; the bacterial fertilizer can be applied to the fields of fruit preservation and bacterial fertilizer biocontrol of the plants; meanwhile, the strain can also be applied to the field of food preservation, is a bacterial strain with multiple functions and wide application fields, and has a good application prospect.

The invention provides a penicillium oxalicum strain K3R2 and a preparation method and application of a biological agent of the penicillium oxalicum strain K3R2. The biocontrol bacterium Penicillium oxalicum strain K3R2 screened by the invention is preserved in the China General Microbiological Culture Collection Center on September 25, 2025, the preservation number is CGMCC NO.42219, and the preservation address is Institute of Microbiology, Chinese Academy of Sciences, No. 3, No.1 yard, Beichen West Road, Chaoyang District, Beijing; the ITS sequence of the Penicillium oxalicum strain K3R2 is as shown in SEQ ID NO: 1, and the CaM sequence is as shown in SEQ ID NO: 2. The penicillium oxalicum strain K3R2 provided by the invention can inhibit hypha growth and spore germination of beet neocam spores, the hypha inhibition rate is 83.60%, the spore inhibition rate is 65.31%, and the penicillium oxalicum strain K3R2 has the effect of preventing and treating quinoa stem blight. Meanwhile, the penicillium oxalicum strain K3R2 has the capabilities of salt resistance, alkali resistance, phosphate solubilization, potassium solubilization, cellulose solubilization and nitrogen fixation; the strain K3R2 remarkably promotes the growth of quinoa plants, so that the chlorophyll content is increased by 20.22%, and the accumulation of nutrient substances is accelerated; the fresh weight, the dry weight and the stem diameter of quinoa plants are increased, and the lodging resistance is enhanced.

This invention relates to the field of fertilizers, specifically to an organic fertilizer containing *Penicillium oxalate* and *Trichoderma echinococcosis*, and its preparation method. The organic fertilizer, by weight percentage, comprises: 10%-25% *Penicillium oxalate*, 10%-25% *Trichoderma echinococcosis*, 10%-20% sheep manure, 5%-10% ammonium phosphate, 5%-10% potassium fertilizer, 10%-20% straw ash, 1%-5% glyphosate, 1%-5% 6-benzylaminopurine, with a binder to make up 100%. The active ingredients of this invention are *Penicillium oxalate* and *Trichoderma echinococcosis*. It is mainly used to increase the yield of vegetables, flowers, and other crops while preventing fungal diseases such as anthracnose and black rot.

The invention discloses application of pseudopenicillin variotii in preparation of a resistance inducer for preventing and treating plant diseases, and belongs to the technical field of plant protection. The invention provides an application of Panax variotii in prevention and treatment of plant diseases, the application concentration of the Panax variotii is 0.1 microgram / mL-1 microgram / mL, a plant resistance inducer containing the Panax variotii can be sprayed on plant leaves or fruit surfaces and has a remarkable prevention effect on anthrax leaf blight, and the higher the concentration is, the better the prevention effect is; the pseudopenicillin variotii can promote synthesis or activity improvement of catalase, peroxidase, polyphenol oxidase, glutathione S-transferase and superoxide dismutase in apple bodies, and also can remarkably induce up-regulation expression of disease-resistant related genes such as MdPR2 and MdPR5, so that the disease resistance, the antioxidant level and the plant immunity of apples are enhanced; a novel and efficient plant resistance inducer application scheme is provided for apple disease control and physiological regulation.

The present application belongs to the technical field of postharvest disease control, and particularly relates to a biocontrol Serratia marcescens and its use for postharvest disease control and storage of pears. The steps are as follows: the Serratia marcescens is activated and cultured, and the bacterial cells are obtained by centrifugation after the culture; the bacterial cells are resuspended in sterile physiological saline to obtain a bacterial suspension; the bacterial suspension is injected into the holes punched on the surface of the pears, and then an equal volume of Penicillium expansum spore suspension is injected, so that the effective control of the Penicillium disease caused by Penicillium expansum is achieved; or the bacterial suspension of the Serratia marcescens is uniformly sprayed on the surface of the pears, and then naturally dried, so that the use for postharvest disease control and storage of the pears is achieved; the present application can significantly reduce the occurrence of the postharvest Penicillium disease of the pears, and reduce the natural rot rate of the pears after harvest, and is safe and environmentally friendly, and not only has no significant adverse effect on the main quality indicators of the postharvest pears, but also can maintain the storage quality of the pears, and achieves a significant technical effect, and has a wide application prospect.

The invention belongs to the technical field of microorganisms, and discloses an amorphophallus bulbifer southern blight infection influence analysis method based on metabonomics and microbiomics. Conjoint analysis shows that core florae (such as Streptomyces, Penicillium and Bauldia) are in significant positive correlation with phenylpropanoids and glutathione (succinic acid, coniferyl alcohol and glutamic acid), succinic acid is in positive correlation with Kribbella and Terrimonas, 2 ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', 2' ', the 3, 3 '-cycle CMP is negatively correlated with pathogen-related bacteria, which indicates that the metabolite regulates and controls the abundance of specific bacteria through positive / negative feedback so as to drive the microecological balance of rhizosphere, and a collaborative defense strategy that plants recruit beneficial microorganisms and inhibit pathogenic bacteria through metabolism reprogramming is disclosed.

This invention discloses a compound fungal agent containing Penicillium citrinum and Trichoderma guizhouense, wherein the Penicillium citrinum is Penicillium citrinum (… Penicillium citrinum NJAU-T106, the Guizhou Trichoderma is Guizhou Trichoderma ( Trichoderma guizhouense NJAU4742. This invention also discloses its preparation method and its application in promoting banana plant growth, increasing banana yield, and controlling banana wilt disease. This invention screened Penicillium citrinum (NJAU4742) from banana disease-suppressing soil to obtain a strain with good biocontrol and growth-promoting effects. Penicillium citrinum The study used NJAU-T106 and innovatively combined it with Trichoderma guiyuanensis NJAU4742 to construct a synergistic system of Penicillium citrinum and Trichoderma guiyuanensis. This effectively reduced the incidence of banana wilt disease while better promoting banana plant growth and increasing banana yield, thereby driving the green and sustainable development of the banana industry.

The application relates to the technical field of edible fungus inoculation, and in particular to a chondrostereum bag inoculation device, which comprises a supporting frame and an inoculation device, the inoculation device comprises an inoculation box fixedly connected to the top of the supporting frame; two sealing plates are arranged in the scheme; after a fungus bag enters the inoculation box, the sealing plates are lowered to the bottom to form a completely closed space, the inoculation process is isolated from the open environment, bacteria spores (such as penicillium and aspergillus) in the air can be avoided from falling into the opening of the fungus bag or the inoculation position, the inoculation needle is made of soft silica gel material, can be slightly deformed with pressure when being inserted into the fungus bag, rigid extrusion and scratch of chondrostereum mycelium caused by traditional metal needles are avoided, the electromagnetic valve and the spiral blade are matched with the elastic sealing valve to send the seed cylinder, quantitative conveying is realized, growth differences caused by too much inoculation (intense nutrition competition) or too little inoculation (mycelium is difficult to quickly occupy space) can be avoided, strain waste caused by excessive inoculation is avoided, and the raw material cost can be significantly reduced in the long term.

The application discloses a kind of steroidal compounds with anti-parkinson disease activity and its preparation method and application.The steroidal compound has the structure as shown in formula (I) or formula (II), or stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug of the structure shown in formula (I) or formula (II).The application is fermented by fungal co-cultivation to alternaria brassicae and penicillium granatum, and the expression of silent gene of strain is promoted by adopting co-cultivation and optimizing medium condition strategy, novel secondary metabolite is obtained, and new steroidal compound with treatment parkinson disease value and application prospect is extracted and separated from co-cultivation ferment, which provides great prospect for the research and development of parkinson disease treatment drugs.

The invention relates to the technical field of microbial fertilizer preparation, and provides a coating method for improving the coating rate of microbial fertilizer particles in order to solve the problem of poor affinity between a hydrophilic material and hydrophobic microbial fertilizer particles and improve the coating rate of the hydrophilic material as a film layer to the microbial fertilizer particles. The fertilizer is composed of a microbial fertilizer particle core layer and a modified film layer coating the outer layer of the fertilizer, and the mass ratio of the core layer to the film layer is 100: (0.5-10). Wherein the core layer can be made of trichoderma harzianum, penicillium baylii or aspergillus niger microbial fertilizer particles; the raw material of the film layer can be composed of the following components: polyvinyl alcohol (PVA), a hydrophilic material (such as starch, glucose, maltose or dextrin) capable of providing glycogen, a surfactant capable of changing the surface tension of water, a wetting agent, a dispersing agent (such as lauryl sodium sulfate, disodium methylene dinaphthalene sulfonate, sodium dodecyl benzene sulfonate or fatty acid salt) and the like. According to the coating method for improving the coating rate of the microbial fertilizer particles, the higher coating rate is achieved, the coated microbial fertilizer further has the longer container life and the higher pressure resistance, the looseness problem is greatly solved, the problems that traditional microbial fertilizer particles are prone to inactivation, breaking and loosening are solved, and the yield of the microbial fertilizer particles is improved. Good popularization and application values are realized.

The invention discloses a solid-state fermentation method of penicillium oxalicum, a penicillium oxalicum complex microbial inoculant and application of the penicillium oxalicum complex microbial inoculant in promoting colonization of the penicillium oxalicum in soil and improving available phosphorus in the soil. The solid-state fermentation method comprises the following steps: mixing a penicillium oxalicum spore suspension and a fermentation substrate for fermentation at 30 + / -0.5 DEG C; the fermentation substrate comprises waste flammulina velutipes residues and wheat bran in a mass ratio of 1: 1. The Penicillium oxalicum complex microbial inoculant comprises the following components in parts by mass: 10-25 parts of a Penicillium oxalicum solid-state fermentation product obtained by a solid-state fermentation method, 20-25 parts of diatomite, 20-30 parts of zeolite powder, 5-10 parts of potassium fulvate and 10-15 parts of humic acid.

The present application relates to a kind of penicillium for plant disease biological control and its application.The present application is obtained by research and screening a new biocontrol agent Penicillium brefeldianum 54-13, the fermentation product thereof can effectively activate the immune induction level of plant, improve the disease resistance of plant caused by wheat powdery mildew, wheat scab and rice blast fungus, including wheat powdery mildew, wheat scab and rice blast fungus etc., provide a safe and environmentally friendly disease control strategy for the sustainable development of wheat and rice.

This invention discloses a novel Atpenin A5-producing strain, Penicillium sp. HDCC00055 (CGMCC NO.23056), which has a high production capacity. Its ability to accumulate Atpenin A5 through fermentation is significantly improved compared to other strains in the prior art, and the Atpenin A5 titer can reach more than 418 mg / L, making it suitable for industrial production.

This invention discloses the application of *Penicillium wani* in improving wheat's resistance to salt-alkali stress and a method for planting wheat in saline-alkali land, belonging to the field of crop cultivation technology. This invention has the advantages of simple operation, rapid processing, and excellent results. The specific method is as follows: during the sowing period, wheat seeds are treated with a low concentration (1 μg / ml) of *Penicillium wani* solution. This treatment can improve wheat's resistance to salt stress at concentrations up to 0.3% and salt-alkali stress at 75 mM (pH 9.2), thereby increasing wheat yield. This invention is applicable to the cultivation of wheat and other crops and has broad prospects for widespread application.

A Penicillium cyclopium strain capable of degrading crop straw fibers efficiently and application thereof are provided. The provided induces mutagenesis of a Penicillium cyclopium strain MP-03 (2554-2) (CGMCC No. 41542) using a nitrosoguanidine method and obtains a mutant strain ΔMP-03 (455-1) (CGMCC No. 41541) with enhanced ability to degrade corn straw. By optimizing a nitrogen-to-carbon ratio of culture medium, culture time, temperature, and a pH range for high enzymatic activity, the mutant strain 455-1 significantly enhances the degradation of corn straw, and endoglucanase and exoglucanase activities in corn straw compared with the non-mutant strain 2554-2. The provided optimizes the conditions for scale-up culture of the mutant strain 455-1, and develops the organic-coupled cultivation technology that integrates a fermentation suspension of the mutant strain 455-1, corn straw and organic fertilizer, which improves the growth, root development and photosynthetic efficiency of greenhouse vegetable, and resistance to the soil-borne oomycete diseases.

The application discloses a strain of Brevibacillus sp. HNCS-1, relates to the technical field of tea tree planting, and has a preservation number of CCTCC NO: M2022713. The strain is classified and named as Brevibacillus sp., and is preserved in the China Center for Type Culture Collection on May 25, 2022, and is located at Wuhan University, Wuhan, China, and has a postal code of 430072. The strain shows significant inhibitory effects on common pathogenic bacteria in tea gardens, such as tea anthracnose bacteria, tea leaf penicillium, tea fusarium, tea white star bacteria, tea round brown spot disease, and tea wheel spot disease, is environment-friendly, and is non-toxic and non-harmful.

This application discloses a Penicillium strain with stress resistance, growth promotion, and insecticidal functions, and its applications. The preservation number of this Penicillium strain is CGMCC No. 42545. This Penicillium strain naturally integrates four functions: salt tolerance, drought tolerance, plant growth promotion, and insecticidal activity against lepidopteran pests. It can grow normally in a 15% NaCl concentration medium, significantly improving plant survival rate under drought stress. Simultaneously, it promotes growth indicators such as root length and root fresh weight in crops like peas. It exhibits highly effective lethal activity against young larvae of lepidopteran pests such as diamondback moth and beet armyworm, and has high safety against non-target organisms. This Penicillium strain can be prepared into solid or liquid inoculants, showing promising application prospects in stress resistance, growth promotion, and pest control for crops grown in saline-alkali / arid areas. It realizes an integrated solution of "stress adaptation - crop growth promotion - pest control," replacing the combined use of multiple single-function agents and reducing agricultural production costs.

The present application provides a kind of compound with PPAR multiple agonist activity and its preparation method and use, the compound is prepared by fermentation of Penicillium (Penicillium) Penicillium pasqualense ) NCPC0626, the preservation unit of the Penicillium is China General Microbiological Culture Collection Center, and the preservation number is CGMCC No.23277.The compound prepared by the present application has multiple PPAR α 、 β And gamma Agonist activity, can be used for preparing drug for treating or preventing PPARs mediated diseases.

The invention discloses pyranopyridone alkaloids, a preparation method thereof and application of the pyranopyridone alkaloids in preparation of antitumor drugs. According to the invention, three pyranopyridone compounds 1-3 with antitumor activity are prepared from Penicillium sp.SCSIO 41320, and the structural formulas of the pyranopyridone compounds 1-3 are shown as a formula (I) in the specification. Experiments prove that the compounds 1-3 have good antineoplastic activity and can be used for developing antineoplastic drugs. The invention provides an alternative compound for developing new antitumor drugs, and has important significance on development of marine microbial drug resources in China.

This invention belongs to the field of biological control technology, specifically relating to a *Penicillium retrievalense* strain for controlling corn stalk rot and its application. The *Penicillium retrievalense* strain is Jnf111, with accession number CGMCC No. 42355, deposited at the China General Microbiological Culture Collection Center on December 10, 2025. The invention verified the inhibitory effect of *Penicillium retrievalense* Jnf111 against *Fusarium graminearum* and *Fusarium graminearum* through plate confrontation experiments. Furthermore, greenhouse efficacy experiments and field experiments showed that *Penicillium retrievalense* Jnf111 can inhibit the lesion area and length of corn sheath rot and corn stalk base rot, indicating that *Penicillium retrievalense* Jnf111 can effectively inhibit the infection of corn sheath rot and corn stalk base rot, which is of great significance for the green control of corn diseases.

The invention discloses a penicillium culture process prediction method and system based on metabolic kinetics decoupling and a hybrid expert network, and the method comprises the steps: constructing a growth trend-metabolic rhythm-random disturbance decoupling framework, and obtaining a random disturbance sequence based on the decoupling framework; constructing a hybrid expert network of four parallel expert networks, and performing multi-step prediction on the random disturbance sequence based on the hybrid expert network to obtain four expert prediction results; constructing fermentation state vectors, inputting the fermentation state vectors into a gating network to obtain weights corresponding to the four experts, and performing weighted average on expert prediction results based on the weights to obtain disturbance term multi-step prediction results; and based on the multi-step prediction result of the disturbance term, combining the extrapolated trend term and rhythm term to obtain a final prediction result. According to the method, specialized processing and self-adaptive fusion of different dynamic characteristics are functionally realized, so that the prediction precision, robustness and interpretability of the penicillium culture process can be remarkably improved.

The invention discloses a low-temperature after-ripening method for malus spectabilis seeds in a desertification-free refrigeration house, and relates to the field of low-temperature after-ripening method.The low-temperature after-ripening method comprises the following steps that S1, multi-dimensional fruit grading and targeted repairing are conducted, directional pretreatment and targeted repair are carried out on fruits with different maturity degrees and damage grades; s2, adaptive stepped pre-cooling: according to the maturity and damage grade of the fruits, different pre-cooling strategies are adapted; s3, performing zoning and layering temperature-changing after-ripening; and S4, carrying out integrated connection treatment. According to the method, fruit maturity and micro-damage grading is completed within 2 h after harvesting, directional pretreatment and targeted repair are matched, the situation that dormancy of low-maturity fruits is not thoroughly removed is avoided, the hidden danger of mold breeding caused by damaged fruits is eliminated, meanwhile, by combining after-ripening environment humidity and gas concentration regulation and control, reproduction of penicillium and fusarium is reduced, the seed mildew rate is reduced, and the seed quality is improved. The after-ripening uniformity of various fruits is improved.

The invention provides Penicillium ochrochloron Ynauu-PO resistant to lead and cadmium and capable of antagonizing panax notoginseng root rot and application of the Penicillium ochrochloron Ynauu-PO, and relates to the field of microorganisms. The preservation number of the penicillium ochrochloron Ynauu-PO is CCTCC NO: M 20252802, the strain can have the capabilities of efficiently resisting lead and cadmium and antagonizing panax notoginseng root rot at the same time, and the technical bottlenecks that the survival rate of microorganisms in high-concentration lead and cadmium polluted soil is low and the remediation effect is poor are solved; an environment-friendly biological control scheme is provided, so that the use of chemical pesticides is reduced, and the environmental pollution and the drug resistance of pathogenic bacteria are avoided.