1048 results about "Bacterial disease" patented technology

The invention discloses a bdellovibrio bacteriovorus for preventing and curing rice bacterial diseases and application thereof. The invention can obtain bdellovibrio bacteriovorus BDFM05 by separationand ultraviolet mutation. The bdellovibrio bacteriovorus BDFM05 is combined with oligosaccharide to obtain bdellovibrio bacteriovorus for preventing and curing crop bacterial diseases. The inventionapplies bdellovibrio bacteriovorus BDFM05 to prevent and cure crop bacterial diseases for the first time. The bdellovibrio bacteriovorus prepared by the method has better rice bacterial diseases preventing and curing effect than common Saisentong, has no toxicity or pollution, is safe to natural enemies of crop diseases and pests, produces no pathogenic bacteria resistance, has no toxic or side effects to people and animals, improves the quality and safety of agricultural products and conforms to the requirements of people on healthy and green food and sustainable-development for agriculturalproduction.

The present invention relates to the field of plant breeding. More specifically, the present invention includes a method of using haploid plants for genetic mapping of traits such as disease resistance. Further, the invention includes a method for breeding corn plants containing quantitative trait loci (QTL) that are associated with resistance to Gray Leaf Spot (GLS), a fungal disease associated with Cercospora spp. The invention further includes a method for breeding corn plants containing QTL that are associated with Goss' Wilt, a bacterial disease associated with Clavibacter michiganense spp.

The invention discloses a tomato SlML1 gene and application, and belongs to the field of biological techniques. The cDNA sequence and the encoding amino acid sequence of the gene are as shown in SEQIDNO.1 and SEQIDNO.2. The transgenosis experiment shows that the gene not only has the functions of improving the quality and increasing the yield of tomatoes, but also has the properties of improving the drought resistance, the fungal disease resistance, bacterial disease resistance and TMV and insect resistance of tomatoes, and moreover the shelf life of tomatoes can be prolonged. Therefore, SlML1 can be used as a target gene introduction plant for improving the quality and the resistance and increasing the yield of plants and has good application prospect in breeding, quality improvement and resistance study on tomatoes.

The present invention relates to a first group of novel bacterial and human associated oligonucleotides, here identified as Genomic Address Messenger or GAM oligonucleotide, and a second group of novel operon-like bacterial and human polynucleotides, here identified as Genomic Record or GR polynucleotide. GAM oligonucleotides selectively inhibit translation of known ‘target’ genes, many of which are known to be involved in various bacterial diseases. Nucleic acid molecules are provided respectively encoding 6444 GAM precursors oligonucleotides, and 726 GR polynucleotides, as are vectors and probes both comprising the nucleic acid molecules, and methods and systems for detecting GAM oligonucleotides and GR polynucleotides and specific functions and utilities thereof, for detecting expression of GAM oligonucleotides and GR polynucleotides, and for selectively enhancing and selectively inhibiting translation of the respective target genes thereof.

The invention relates to an irradiation device and method for the treatment of totally or partially cell-mediated inflammations of the skin, the connective tissue and the viscera, viral and other infectious diseases such as HIV and prionic infections, fungal infections of the skin and the mucous membranes, bacterial diseases of the skin and the mucous membranes as well hand eczema and anal eczema which comprises at least one irradiation device to irradiate a surface treatment area where the wavelength of the emitted radiation to a treatment area is longer than 400 nm and comprises at least one spectral band between 400-500 nm while the radiation device has a gas discharge lamp containing at least gallium, indium or their respective halides as irradiation source, means that less than 7% of the overall optical output are emitted in the UV range, wherein at least 30% of the optical output are emitted in the range of 400-500 nm; and contains means for the generation of optical pulses towards a treatment area with a power density of the optical pulse peaks larger than 0.5 W/cm² and smaller than 500 W/cm². The energy of one pulse relates to 0.05-10 J/cm².

The invention discloses a composite for preventing and controlling an agricultural bacterial disease, and belongs to the technical field of plant protection pesticides. The composite comprises an active component A and an active component B, wherein the active component A is benziothiazolinone; the active component B is one or two of cymoxanil, qingkuling, yekuzuo, bismerthiazol, ethylicin, thiram, dioctyl divinyltriamino glycine, active ester, metalaxyl, chlorothalonil, dithiocyano-methane, bromine chlorine hydantoin, 2-bromine-2-nitryl-1,3-propylene glycol and moroxydine hydrochloride; the weight ratio of the active component A to the active component B is 1:100 to 100:1. The composite disclosed by the invention obtains the synergetic effect through the mixing of the benziothiazolinone and other bacterial medications and is used for agricultural production.

The invention discloses a method for extracting chlorogenic acid from folium cortex eucommiae. The invention also discloses an application of the chlorogenic acid in prevention substances of fish diseases. The method comprises the steps of grinding, enzyme treatment, ultrasonication, filtering, extraction, concentration, purification, and the like; the method has the advantages of simple and convenient technique operation, low cost, no hazardous solvent, high yield, being applicable to industrialized production, and the like; in addition, the chlorogenic acid has good bacteriostasis effect on pathogenic bacteria commonly seen in aquiculture, with a bacteriostasis effect on aeromonas hydrophila equal to that of antibacterials like antibiotics, can strengthen the immunity of the organism and has relatively strong prevention effect on bacterial diseases.

This invention pertains generally to the field of chemical synthesis and purification, and more specifically to methods of synthesizing and purifying certain 3,7-diaminophenothiazin-5-ium compounds (referred to herein as “diaminophenothiazinium compounds”) including Methythioninium Chloride (MTC) (also known as Methylene Blue). In one embodiment, the method comprises the steps of, in order: nitrosylation (NOS); nitrosyl reduction (NR); thiosulfonic acid formation (TSAF); oxidative coupling (OC); Cr(VI) reduction (CR); isolation and purification of zwitterionic intermediate (IAPOZI); ring closure (RC); chloride salt formation (CSF); one of: sulphide treatment (ST); dimethyldithiocarbamate treatment (DT); carbonate treatment (CT); ethylenediaminetetraacetic acid treatment (EDTAT); organic extraction (OE); and recrystallisation (RX). The present invention also pertains to the resulting (high purity) compounds, compositions comprising them (e.g., tablets, capsules), and their use in methods of inactivating pathogens, and methods of medical treatment and diagnosis, etc., for example, for tauopathies, Alzheimer's disease (AD), skin cancer, melanoma, viral diseases, bacterial diseases, or protozoal diseases.

The invention provides a salt-resistance Bacillusmethylotrophicus strain LJ and an application thereof. The salt-resistance Bacillusmethylotrophicus strain LJ is classified to be named as Bacillusmethylotrophicus, and the collection number of the salt-resistance Bacillusmethylotrophicus strain LJ is CGMCCNO.7570. By performing salt tolerance analysis on the salt-resistance Bacillusmethylotrophicus strain LJ, performing a pathogenicity test on crops, and performing a test on the inhibition effect of the strain on pathogenic bacteria, results show that the salt tolerance degree of the strain is 25-30%; the strain can not cause pathogenicity to the crops, has relatively ideal inhibition effects on bacterial diseases, viral diseases and fungous diseases of tobaccos, can be compounded with a great number of elements, is long in retention period and high in effective bacterium survival rate, can be applied to saline-alkali soils, and has the effects of improving the soil, resisting the diseases, increasing the yield and the like. The salt-resistance Bacillusmethylotrophicus strain LJ disclosed by the invention ensures that a microbial preparation has the positive effects of preventing the diseases and promoting the growth of plants in special environments; the microbial inoculum has the effects of salt-resistant growth-promoting bacteria and disease-prevention growth-promoting bacteria, and is suitable for improvement of salt marsh, alkali soil and acid soil.

A foliarly applicable plant nutrient composition comprises, in aqueous solution, (a) a first component comprising an agriculturally acceptable source of foliarly absorbable silicon; (b) a second component selected from agriculturally acceptable sources of thiosulfate ions, agents effective to inhibit polymerization of silicic acid or silicate ions, and mixtures thereof; and (c) as a third component, an agriculturally acceptable mixture of compounds selected from the group consisting of organic acids, organic compounds having funtional groups capable of reversibly binding or complexing with inorganic anions, and mixtures thereof. The composition is useful for silicon nutrition of a plant and for reducing susceptibility of a plant to fungal or bacterial disease.

The present invention relates to phage isolates having a strong lytic activity against pathogenic Enterobacteriaceae such as Escherichia coli and/or Salmonella strains and their use in various human or pet food products for the treatment or prevention of bacterial diseases caused by pathogenic Enterobacteriaceae such as Escherichia coli, in particular for phage therapy of pediatric gastroenteritis, or Salmonella infection. It also relates to human or pet food products prepared thereof.

The invention relates to an oligosaccharide-containing compound bactericide. The used oligosaccharides comprise one or more of sodium alginate oligosaccharide and its derivatives, chitin oligosaccharide and its derivatives, and oligogalacturonic acid and its derivatives, and a broad-spectrum bactericide benziothiazolinone. Through mixing of the above materials according to different ratios, the soluble compound is obtained and has synergism of preventing and treating a plurality of bacterial diseases and fungous diseases such as cucumber downy mildew, pear scab, apple scab, apple rot, citrus anthracnose, citrus bacterial canker and anthracnose of grape. 2.5-10% of the oligosaccharide and its derivative, 0.5-4.0% of benziothiazolinone, and 5-10% of ammonium hydroxide as a cosolvent and 0.2-10% of sodium hydroxide as a cosolvent are mixed, and the mixture is diluted by 1000 times and has a bacteriostasis rate of 40-99%. The compound of the oligosaccharide and its derivative and the benziothiazolinone has the original characteristics of high efficiency, low toxicity and safety of a benziothiazolinone bactericide, contains oligosaccharide biological pesticide, reduces a chemosynthetic bactericide use amount, prevents or delays resistance to bactericide, improves crop defense response and yield, improves agricultural product quality, improves application safety and is an eco-friendly novel compound bactericide.

Improved methods and compositions for protecting plants or seeds from plant diseases are provided. The compositions comprise (and preferably consist essentially of) saponin, such as triterpene type saponins extracted from quinoa or quillaja. Compositions according to the invention may comprise (or consist essentially of) a quantity of a sapogenin compound, preferably a sapogenins selected from the group consisting of oleanolic acid, hederagenin, phytolaccinic acid, and quillaic acid. The methods comprise contacting the portion of the plant (e.g., foliage, shoot, etc.) to be treated with a disease-inhibiting or protective amount of the composition. The compositions can also be used to treat plant seeds or tubers prior to planting thereof, as well as soil adjacent a growing plant. The inventive compositions are particularly useful for the treatment, control and/or prevention of bacterial diseases. The saponins of the invention can be applied as liquids or dry particulates, and are especially suited for the treatment of tomato and potato plants and their respective seeds.

The present invention is directed to methods and compositions to prevent or treat a honey bee pathogen infection (e.g., Melissococcus plutonis, Paenibacillus larvae, Ascosphaera apis). Specifically, the invention provides for the treatment or prevention of European or American foulbrood or chalkbrood. In addition, the invention provides methods for controlling Varroa mites that can weaken a hive or act as vectors for bacterial diseases. In further embodiments, the invention provides for the treatment or prevention of hive infestations with Lepidopteran pests, such as the wax moth (Galleria mellonella).

The invention discloses a kind of 1-substituted-5-trifluoromethyl-4-pyrazol-1,3,4-oxadiazole thioether or sulfone derivatives and application of the derivatives. The derivatives have the structures represented by general formulae A and B shown in the specification. 1-substituted-5-trifluoromethyl-4-pyrazol-1,3,4-oxadiazole compounds are synthesized from ethyl trifluoroacetoacetate by the following five reactions: esterification, ring closure, hydrazinolysis, ring closure and substitution. The compounds have certain inhibition effects to plant bacterial diseases or plant fungous diseases and can be used as pesticides and pesticide additives for preventing and controlling the plant bacterial diseases or the plant fungous diseases.

The invention discloses a green agricultural compound Chinese herbal medicine bactericide which is prepared from the following Chinese herbal medicines: schisandra chinensis, eucommia ulmoides, alpinia oxyphylla, bighead atractylodes rhizome, bletilla striata, radix scutellariae, radix stemonae, semen strychni, sophora flavescens, arundo donax, radix ophiopogonis, dandelion, liquorice, rheum officinale, radix lithospermi, clove, cortex magnoliae officinalis, fructus forsythiae and coptis chinensis; the bactericide is prepared by extracting the Chinese herbal medicines by alcohol; the bactericide is mainly used for controlling various diseases of various crops caused by fungi, so that the disease resistance and the immunologic function of the crops can be improved. After the green agricultural compound Chinese herbal medicine bactericide is used, the defects that the environment is polluted by the chemical pesticide and the drug resistance is easily caused can be overcome, and the problems that the biological pesticide is small in sterilization range and slow in pesticide effect can be solved; the green agricultural compound Chinese herbal medicine bactericide can be used for controlling various fungal and bacterial diseases of plants, does not cause drug resistance after being used for a long time, and is less in environmental pollution and harmless to people and livestock.

The invention discloses an Apis cerana royal jelly antibacterial peptide AccRoyalisin gene and an encoded polypeptide thereof and application thereof. The gene has a DNA sequence shown as SEQ ID No.4; and the encoded protein of the gene has an amino acid sequence shown as SEQ ID No.5. The antibacterial peptide gene can establish a high-expression genetic engineering strain by building an Escherichia coli expression vector, and performing producing and separating and purifying on a recombinant product through induction expression of the fermentation engineering. The recombinant product thereof has an obvious inhibiting effect on a plurality of gram positive bacteria, such as bacillus subtilis, staphylococcus aureus and micrococcus flavus and the like, can be used for preserving and refreshing foods, in particular for preventing food-born bacterial contamination, is harmless to human body and animals, can serve as a substitute of antibiotics and chemical preservatives and is also suitable for preventing and controlling bred animal bacterial diseases. The Apis cerana royal jelly antibacterial peptide AccRoyalisin gene and the encoded polypeptide thereof lay a foundation for the development, the massive industrial production and the application of the Royalisin.

The invention relates to antisepsis and anti-inflammation medicaments, and particularly relates to high-content liquid povidone-iodine. The liquid povidone-iodine is prepared from the following raw materials in percentage by weight: 5.2-12.24 percent of iodine, 10-24 percent of polyvinylpyrrolidone, 2-4.8 percent of potassium iodide, 0.1-0.24 percent of potassium iodate, 15-36 percent of ethanol and the balance of water. The high-content liquid povidone-iodine is a reddish brown viscous liquid, is easily dissolved in water, has stable performance, strong sterilization efficacy and no irritation, is suitable for sterilization of operating parts and skin-mucosa or sterilization of aquatic water, can be used for preventing and treating bacteriosis of aquatic animals caused by vibrio, aeromonas hydrophila, edwardsiella tarda and the like and sterilizing the environment of livestock and poultry housings, plays a role in killing multiple bacteria, spores, viruses, fungi and the like, thus being a good iodine containing medical bactericide and epidemic prevention sanitizer.

A therapeutic composition or a vaccine comprising tumor membrane-anchored cytokines or other immunostimulatory or costimulatory molecules are provided. The therapeutic composition or a tumor vaccine can be used for treating a tumor or other disease such as autoimmune disorder, viral diseases, bacterial diseases, parasitic diseases, and transplant rejection.

The invention relates to the field of aquaculture, and discloses a broad-spectrum bacteriophage preparation for aquaculture and a reparation method thereof. The bacteriophage preparation is prepared by fermenting a bacteriophage strain with a collection number of CGMCC No.9623 through a gene engineering escherichia coli DH5alpha serving as a host bacterium. The preparation method comprises the following steps: (1) adding the escherichia coli DH5alpha into a culture medium for fermental cultivation, thereby obtaining a host bacterium fermented solution; (2) feeding bacteriophage and MgCl2 mother liquid into the host bacterium fermented solution for uniform mixing, and then performing stewing and multiplication culture, thereby obtaining a fermented mixed solution; (3) centrifugating the fermented mixed solution, thereby obtaining the bacteriophage preparation. The broad-spectrum bacteriophage preparation disclosed by the invention has splitting action on various aquacultured pathogenicbacteria, and can be independently used or used with other microecological preparations. Furthermore, the host bacterium adopts a gene engineering bacterium. The preparation method is simple, convenient and safe to use, has no side effects and can be popularized and applied to prevention and treatment of bacterial diseases of aquaculture.