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650 results about "Disease prevention" patented technology

Mortierella alpina strain and application thereof in plant growth promotion, disease prevention and soil improvement

PendingCN121086895ABiocideAgriculture tools and machinesBiotechnologyPhytophthora sp.
The invention relates to the field of microorganisms, in particular to a mortierella alpina strain MA with a plant growth promoting function and application of the mortierella alpina strain MA. The strain has remarkable nitrogen fixation, siderophore production, auxin (IAA) production and cellulase activity, can inhibit various soil-borne pathogenic bacteria such as phytophthora capsici and fusarium, and remarkably improves the disease resistance and growth performance of crops such as pepper. The strain has various functions and broad-spectrum action, is suitable for replacing part of chemical fertilizers and pesticides in intensive agriculture, and realizes green and efficient planting of crops.
Owner:YUNNAN AGRICULTURAL UNIVERSITY

Shrimp health status early warning method and system based on water quality monitoring

The invention discloses a shrimp health state early warning method and system based on water quality monitoring, and aims to improve the disease prevention and control efficiency in a shrimp culture process. The method comprises the following steps: collecting historical breeding disease data and water quality change data of a target shrimp breeding water area, and constructing a water quality pathopoiesis knowledge graph; then water quality change data in a preset monitoring time period is obtained, space-time tracing is carried out by using the water quality change prediction model, and a water quality anomaly propagation path diagram is generated; formulating a water quality monitoring strategy based on the propagation path diagram, and optimizing the layout and frequency of monitoring points; and finally, monitoring the water quality in real time according to the established monitoring strategy, and realizing dynamic early warning of the health state of the prawns by combining real-time monitoring data and a water quality pathopoiesis knowledge graph. Water quality related diseases can be effectively prevented and controlled, and the stability and yield of shrimp culture are improved.
Owner:海南省水产品质量安全检测中心

Tilletia controversa Kuhn effect protein g16561 and application thereof

The invention belongs to the field of prevention and treatment of tilletia controversa Kuhn, and particularly relates to a tilletia controversa Kuhn effect protein g16561 and application thereof. An amino acid sequence of the Tilletia controversa Kuhn effect protein is shown as SEQ ID NO: 2. The effect protein plays an important role in the process of inhibiting plant defense reaction, and has an interaction relationship with a wheat protein in the process of infecting wheat by Tilletia controversa Kuhn. According to the invention, the pathogenesis of Tilletia controversa Kuhn can be deeply researched, and the excavation of wheat disease-resistant genes and the cultivation of wheat disease-resistant varieties can be promoted.
Owner:SANYA NATIONAL INSTITUTE OF SOUTHERN BREEDING CHINESE ACADEMY OF AGRICULTURAL SCIENCES +2

Burkholderia and application thereof in prevention and treatment of eucalyptus blight

The invention discloses a Burkholderia sp. Strain and an application thereof in prevention and treatment of eucalyptus blight. The Burkholderia sp. AS-SF-1 disclosed by the invention has the preservation number of GDMCC (Graphical December Microorganism Center) No. 66223; the culture and volatile matter of the strain can inhibit growth of various forest pathogenic bacteria, the eucalyptus has a remarkable control effect on branch blight, siderophore can be generated, absorption and utilization of iron can be promoted, various types of carbon sources or nitrogen sources can be utilized, and the strain can grow within the pH range of 4-9. The burkholderia sp. AS-SF-1 disclosed by the invention has an important application value on planting of eucalyptus and prevention of diseases.
Owner:GUANGDONG ECO ENGINEERING POLYTECHNIC +1

Toxoplasma gondii attenuated vaccine strain RHdeltarop67 as well as construction method and application thereof

The invention discloses a toxoplasma gondii attenuated vaccine strain RH delta rop67 as well as a construction method and application thereof, and belongs to the technical field of parasitic disease prevention and control and biological product preparation. The attenuated vaccine strain is constructed by performing targeted knockout on the ROP67 gene in a toxoplasma gondii strain RH delta ku80 through a CRISPR / Cas9 mediated gene editing technology. Compared with a wild type strain, the attenuated vaccine strain shows remarkable attenuation characteristic and good immunogenicity. A test result shows that the attenuated vaccine strain can induce a host to generate specific immune response mainly based on cellular immunity, maintains a protection effect on toxoplasma gondii infection in a relatively long immune period, and has a protection effect on tachyzoite infection and a chronic infection stage of toxoplasma gondii strains with different virulence; the survival ability of a host to tachyzoite infection can be improved, and the formation level of cysts in tissues is reduced. The invention provides a technical scheme with long-term immune potential for research and development of toxoplasma gondii attenuated vaccines.
Owner:SHANXI AGRI UNIV

Microbial agent and application thereof in prevention and treatment of rice blast and promotion of rice growth

The invention discloses a microbial agent and application thereof in preventing and treating rice blast and promoting rice growth, active ingredients of the microbial agent are formed by compounding cold bacillus with the preservation number of CGMCC (China General Microbiological Culture Collection Center) NO: 33492 and bacillus velezensis with the preservation number of CGMCC NO: 33493, and the microbial agent aims at solving the synergistic problem of preventing and treating rice blast and promoting rice growth. According to the complex microbial inoculant, through the synergistic interaction between the two strains, the metabolite of the complex microbial inoculant can completely inhibit the spore germination of magnaporthe oryzae; meanwhile, the fungicide can degrade cellulose, obviously promote the growth of plant height, fresh weight and dry weight of rice, and realize the integration of disease prevention and growth promotion. The invention further discloses a preparation method of the fungicide and an application method of the fungicide for preventing and treating rice blast and promoting growth in a root irrigation mode in the three-leaf stage of rice. The microbial agent disclosed by the invention has dual functions of efficiently preventing diseases and stably promoting growth, and an efficient and safe biological solution is provided for green and sustainable development of agriculture.
Owner:SHENYANG AGRI UNIV

Monoclonal antibody pair for detecting feline immunodeficiency virus p24 protein and application thereof

The application belongs to the technical field of biological detection, and particularly relates to a monoclonal antibody pair for detecting feline immunodeficiency virus p24 protein and application thereof. The monoclonal antibody pair is monoclonal antibody 1D8 and monoclonal antibody 1H10, which can specifically recognize feline immunodeficiency virus p24 protein, and the heavy chain and light chain variable region complementarity determining region sequences of 1D8 and 1H10 are clear, and are respectively shown as SEQ ID NO. 1-12. The antibody pair can effectively avoid cross reaction, and significantly improve the accuracy and sensitivity of detection; the colloidal gold detection test strip constructed based on the antibody pair is simple and fast in operation, is suitable for early antigen detection of FIV infection, solves the problem that existing antibody detection cannot distinguish natural infection and vaccine immunization, and provides a reliable technical means for on-site screening and disease prevention and control of FIV.
Owner:BEIJING SUBENYUANHE BIOTECHNOLOGY CO LTD

Water-saving irrigation system for intelligent agricultural vegetable seedling culture

The invention particularly relates to a water-saving irrigation system for intelligent agricultural vegetable seedling raising, and relates to the technical field of intelligent agriculture. And a decision and processing module. According to the method, multi-dimensional data perception and intelligent decision are adopted, so that the core contradiction that disease prevention needs drying and seedling strengthening needs stress in traditional seedling culture is solved; through a non-contact infrared leaf temperature sensor, a miniature resistance-type leaf surface humidity-sensitive sensor and the like, key data such as leaf temperature and leaf surface humidity state are accurately collected, a leaf surface humidity prediction model is constructed, a disease risk window is divided in advance, and propagation of diseases such as downy mildew and gray mold is blocked from the source; the stress intensity is controlled through the wilting coefficient, so that the seedlings are prevented from withering due to excessive stress, and moderate drought is ensured to stimulate root growth.
Owner:XIANGYUN TAIXING AGRI TECH DEV CO LTD

Application of arabidopsis thaliana RK3 gene and S structural domain receptor kinase RK3 coded by arabidopsis thaliana RK3 gene in improvement of plant disease resistance

The invention discloses an arabidopsis thaliana RK3 gene and application of S structural domain receptor kinase RK3 coded by the arabidopsis thaliana RK3 gene in improvement of plant disease resistance, and belongs to the technical field of plant genetic engineering. According to the application of the arabidopsis thaliana RK3 gene to improvement of plant disease resistance, the nucleotide sequence of the arabidopsis thaliana RK3 gene is shown as SEQ ID NO.1, the amino acid sequence of S structural domain receptor kinase RK3 coded by the arabidopsis thaliana RK3 gene is shown as SEQ ID NO.2, and further plants are selected from arabidopsis thaliana, oilseed rape, rice, tomatoes, potatoes, peanuts, soybeans, cotton, tobacco, cucumbers, watermelons and the like. The expression of the plant disease resistance comprises infection resistance to wild-type pseudomonas syringae, effector engineering strains thereof and botrytis cinerea. It is clear that the arabidopsis thaliana RK3 gene and the encoded protein thereof can remarkably enhance the infection resistance of plants to various pathogenic bacteria for the first time, disease prevention and control are achieved by activating the autoimmune system of the plants, and an effective path is provided for reducing chemical pesticide application and promoting agricultural green development.
Owner:SHANGHAI NORMAL UNIVERSITY

Fungus effect protein prediction model based on protein language model and deep learning

PendingCN121122416ABiostatisticsBiological modelsBiotechnology researchDrug development
The invention discloses a fungal effect protein prediction model based on a protein language model and deep learning, and relates to the technical field of bioinformatics and deep learning, and the method comprises the steps: 1, collecting fungal effect protein data and non-effect protein data; 2, obtaining protein embedding through a protein language model; 3, performing oversampling processing on the data; 4, constructing a deep learning model; 5, model training; and 6, performing cross validation and independent test evaluation. According to the invention, a geometric oversampling technology (G-SMOTE) is adopted to carry out oversampling processing, so that the problem of sample imbalance is solved; a protein language model is adopted to obtain protein embedding characteristics to strengthen protein expression; and the prediction accuracy is improved by using a deep learning model architecture. The method can be applied to agricultural disease prevention and control, drug development and biotechnology research, important support is provided for identification and research of fungal effect protein, prediction accuracy can be improved, dependence on expensive experiments is reduced, and labor cost is reduced.
Owner:HAINAN UNIV

Application of bacillus amyloliquefaciens BA-89 in crop growth promotion and verticillium dahliae antagonism

PendingCN121271760ABiocidePlant growth regulatorsBiotechnologyPhytophthora sp.
The invention relates to the technical field of microorganisms, and particularly provides application of bacillus amyloliquefaciens BA-89 in crop growth promotion and verticillium dahliae antagonism. The strain is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.36498. The strain can secrete multiple extracellular enzymes (including protease, amylase, cellulase and glucanase), has the growth promoting characteristics of producing ammonia, dissolving potassium and the like, and can tolerate high temperature and ultraviolet stress; the compound has a remarkable antagonistic effect on various plant pathogenic bacteria (such as verticillium dahliae, fusarium oxysporum and phytophthora capsici); by inoculating the strain on cotton, the plant growth can be obviously promoted, the plant height, stem diameter, root length, leaf area and biomass are improved, and meanwhile, the disease index of verticillium wilt and the colonization amount of pathogenic bacteria at the root are effectively reduced. The strain disclosed by the invention can be used as a biological fertilizer and a biological pesticide, is used for cotton cultivation and disease prevention and control, and has a wide application prospect.
Owner:SANYA NATIONAL INSTITUTE OF SOUTHERN BREEDING CHINESE ACADEMY OF AGRICULTURAL SCIENCES +2

Bacillus velezensis B127 and application thereof

PendingCN121852255ABiocideAgriculture tools and machinesBiotechnologyMicroorganism preservation
The invention discloses bacillus velezensis B127 and application thereof, the bacillus velezensis is preserved in China Center for Type Microbiological Culture Collection, the preservation number is CCTCC NO: M 20252878, the preservation date is December 15, 2025, the classification name is bacillus velezensis B127, and the preservation address is Wuhan University, Hubei Province. The bacillus velezensis B127 has a remarkable inhibition effect on various tobacco fusarium pathogenic bacteria, has good phosphorus and potassium solubilizing capacity, generates hydrolase related to inhibition of pathogenic bacteria and generates siderophore and indoleacetic acid for promoting plant growth, is a biocontrol bacterium with excellent comprehensive performance, and can be widely applied to the field of biological control. The method has good development and application prospects in the fields of agricultural disease control, soil improvement, microbial fertilizers and the like.
Owner:CHINA TOBACCO HUNAN IND CORP

Personalized health management service system based on multi-source data fusion

The invention belongs to the technical field of health information processing and management, and discloses a personalized health management service system based on multi-source data fusion, which comprises a data acquisition device access wearable device, a health application, a medical information system and a user terminal entry data, the fusion processing platform carries out missing completion, abnormity elimination, time alignment and weighted fusion on the data to form a weighted fusion sequence, the cross-domain correlation builder generates a correlation map of lifestyles and clinical indexes, and the risk modeling engine outputs individual health risks under the constraint of the map. The management scheme generator generates personalized diet, exercise, sleep and disease prevention schemes under the constraint of the rule base. The compliance evaluation system combines subjective feedback and objective monitoring to form scores, the scheme adjustment mechanism executes minimum disturbance update based on scores and atlas trends, and the auditing unit realizes whole-process data tracing and compliance guarantee.
Owner:BEIJING RONG MEDIA ZHIZHONG NETWORK TECH CO LTD

Thyroid whole-cycle health management method

The invention relates to the field of medical health management, and discloses a thyroid-oriented whole-cycle health management method, which comprises the following steps of: firstly obtaining thyroid multi-source information data of a target population to form a data set, then extracting fusion features to generate a time sequence feature vector, and analyzing and calculating occurrence risk factors and scores of feature dimensions in a preset time window according to the time sequence feature vector; a comprehensive risk score is obtained through time sequence analysis, risk grades are divided, high-risk individuals are marked, and a personalized screening strategy is generated; then combining historical data of high-risk individuals, analyzing key driving paths with high risk scores, associating an external knowledge base to predict recurrence frequency, and finally dynamically adjusting and optimizing screening and intervention strategies according to the recurrence frequency; precise evaluation, grading and personalized management of individual thyroid health risks are achieved, then risk key driving paths are found out, recurrence is predicted, and the strategy is dynamically optimized to improve the disease prevention and treatment effect.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Disease and pest question answering system fusing knowledge graph and large model

The invention relates to the field of knowledge questions and answers, in particular to a disease and insect pest questions and answers system fusing a knowledge graph and a large model. The uniqueness and accuracy of underlying facts are ensured through an automatic extraction and disambiguation mechanism driven by a large model, and the illusion phenomenon of the large model is effectively inhibited in combination with hard constraints of a knowledge graph, so that the accuracy and preciseness of disease and pest control suggestions are superior to those of a traditional data-driven method; the deep semantic understanding capability of the large language model is utilized, oral expressions, wrongly written characters and implicit intentions of peasant households are accurately recognized, compared with syntactic rule matching in the prior art, the misdiagnosis and omission ratio can be greatly reduced, and higher practicability is shown in a complex consultation scene; structured multi-source data representing expert knowledge is seamlessly fused into a large model generation process, an output result has professional constraints and conforms to human language habits, logic is smooth, the sense of speech is natural, and the interactive experience is far better than that of stiff template reply in the prior art.
Owner:YUNNAN AGRICULTURAL UNIVERSITY

Application of Ustilaginoidea virens secretory protein UvWMT and coding gene thereof in prevention and control of plant diseases

The invention provides application of Ustilaginoidea virens secretory protein UvWMT and a coding gene thereof in prevention and control of plant diseases. The gene sequence of the Ustilaginoidea virens secretory protein UvWMT is researched, found and cloned for the first time, and the new application of the Ustilaginoidea virens secretory protein UvWMT in disease-resistant breeding of crops such as rice is developed. Research finds that the protein is a key pathogenic factor in the process that rice is infected by ustilaginoidea virens, heterologous expression experiments further find that heterologous expression of UvWMT in rice can significantly improve the resistance of crops to various pathogenic bacteria such as ustilaginoidea virens, magnaporthe oryzae and xanthomonas oryzae, and has no significant difference in key agronomic traits compared with a wild type. An important theoretical basis is provided for rice disease-resistant breeding, crops can be safely and effectively endowed with broad-spectrum disease resistance by heterologous expression of the gene, and the gene has great application prospects and economic values in the aspects of crop breeding disease resistance improvement, rice disease prevention and control and crop yield increase and pesticide reduction.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Application of FaPDHE1alpha gene or encoding protein thereof in prevention and control of strawberry gray mold

The invention relates to an application of a FaPDHE1alpha gene or an encoding protein thereof in prevention and control of strawberry gray mold, and belongs to the field of plant genetic engineering and the field of prevention and control of postharvest diseases of fruits and vegetables. The invention discloses a key positive regulation and control effect of FaPDHE1alpha in regulation and control of strawberry gray mold resistance. By constructing a 35S:: FaPDHE1alpha overexpression vector and a FaPDHE1alpha RNAi interference vector, according to transient gene overexpression and RNA interference silencing tests, it is verified that high expression of the FaPDHE1alpha gene can obviously enhance the resistance of strawberry fruits to botrytis cinerea, and silencing of the gene causes reduction of the disease resistance of the fruits. Mechanism studies show that after the FaPDHE1alpha gene is activated, mitochondrial energy metabolism and controlled ROS signal generation are promoted, antioxidant enzyme activity is enhanced, and defense related gene expression is induced, so that the disease resistance of fruits is improved. By means of functional genomics, the key function of the FaPDHE1alpha gene in prevention and control of gray mold after strawberry harvest is illuminated for the first time, and the FaPDHE1alpha gene can be used for screening disease-resistant breeding materials or developing biological prevention and control preparations for postharvest diseases and has important application value.
Owner:SHANGHAI JIAOTONG UNIV

Anti-human Trop-2 antibody and application thereof

The present invention provides an antibody binding a human tumor-associated calcium signal sensor 2 (Trop-2) protein or fragments thereof, and use of the antibody or fragments thereof in preventing or treating diseases. The antibody or fragments thereof of the present invention can effectively bind to the human Trop-2 protein, and have internalization activity, and the internalization activity is enhanced after ADC drug labeling, and the in vivo efficacy and safety of a mouse model are not lower than those of a control antibody.
Owner:MABWELL (SHANGHAI) BIOSCIENCE CO LTD

Laying hen genetic disease knowledge graph construction and intelligent decision support system

The invention discloses a laying hen genetic disease knowledge graph construction and intelligent decision support system. The system comprises a genetic disease weak supervision graph extraction module, a disease multi-factor diagnosis module, a group health risk clustering module, a multi-omics graph analysis module, a genetic disease knowledge graph construction module and an intelligent decision support module. According to the system, laying hen genes, physiological indexes, breeding environments and multi-omics data are collected through gene sequencing and the like, a gene disease association graph is generated through weak supervision graph extraction, a disease diagnosis result is generated through multi-factor diagnosis, health risk grades are divided through risk clustering, and an association graph is generated through multi-omics analysis; and a genetic disease knowledge graph is constructed, and an intelligent decision scheme is generated in combination with real-time data and an algorithm. The system improves the accuracy of laying hen genetic disease prevention and control and the intelligent level of breeding management, guarantees the economic benefits of breeding, and is suitable for large-scale breeding scenes of laying hens.
Owner:CHINA AGRI UNIV

Monoclonal antibody for resisting human B-type adenovirus and application of monoclonal antibody

The invention belongs to the technical field of biology, and discloses an anti-human B-type adenovirus monoclonal antibody and application thereof. The monoclonal antibodies 10G12, 12F12, 2E8 and 2F5 provided by the invention can be effectively combined with the type 3 or 55 human adenovirus, and have very strong neutralizing activity on the type 3 or 55 human adenovirus. The clinical application value of preventing and treating adenovirus infection is realized; the compound can be used for detecting adenovirus, diagnosing diseases related to adenovirus infection, and preventing and / or treating adenovirus infection and / or diseases related to adenovirus infection.
Owner:SOUTHERN MEDICAL UNIVERSITY

Intelligent closed-loop hypertension management method and system based on wearable device and wearable device

The invention belongs to the technical field of blood pressure management, and provides an intelligent closed-loop hypertension management method, system and equipment based on wearable equipment, and the method comprises the steps: applying controllable peripheral pressure to the body of a user through the wearable equipment, and inducing local blood flow change in a pressed area; according to the method, the peripheral pressure stimulation and blood pressure monitoring are combined, continuous blood pressure signals of a user are collected in real time, the instantaneous reference blood pressure value of the continuous blood pressure signals is calibrated, the system can dynamically adjust the peripheral pressure currently applied by the wearable device and regulation and control parameters after calibration, a self-adaptive closed loop is formed by peripheral pressure stimulation and blood pressure monitoring, and pressure stimulation can be applied again according to needs. According to the scheme, controllable peripheral pressure stimulation and undisturbed continuous blood pressure monitoring are combined, real-time self-adaptive hemodynamic adjustment and intelligent closed-loop control are achieved, a continuous and real-time intelligent closed-loop hypertension management mechanism is constructed, blood pressure management covering all time periods and all scenes can be achieved, and the blood pressure monitoring accuracy is improved. The composition is suitable for hypertension regulation and control, cardiovascular and cerebrovascular disease prevention and individualized treatment assistance.
Owner:LIANZHI HEALTH TECHNOLOGY CO LTD

Bacillus safensis and application thereof in aquaculture

The invention discloses a bacillus safensis strain and application thereof in aquaculture, and relates to the technical field of aquaculture disease prevention and control, the obtained bacillus safensis strain ZY-1 forms spores under a certain fermentation condition, can be prepared into powder for preservation, has a long shelf life, has the bacteriostatic activity retention rate of more than or equal to 85% after being stored in a dark place for 12 months at 4-25 DEG C, and has the antibacterial activity of more than or equal to 7.2%. The production, transportation and storage cost is saved, main bacteriostatic effect factors of the bacillus safensis ZY-1 strain exist in extracellular metabolites, the bacillus safensis ZY-1 strain is stable in performance and resistant to high temperature, acid and alkali, ultraviolet rays, protease and the like, and fermentation supernatant of the bacillus safensis ZY-1 strain can be directly applied or prepared into spray-dried powder and is suitable for various aquaculture application scenes such as pond splashing and feed mixing and feeding. The metabolite spray-dried powder has a remarkable killing effect on high-pathogenicity vibrios VpAHPND and VpTPD, the minimum inhibitory concentrations of metabolite spray-dried powder respectively reach 23.44-46.88 mu g / ml and 46.88-93.75 mu g / ml, and the metabolite spray-dried powder can be used for preventing and controlling prawn infectious hepatopancreas necrosis and prawn transparent larva diseases induced by the metabolite spray-dried powder and also has a certain killing function on pathogens of other aquatic animals.
Owner:OCEAN UNIV OF CHINA

Linear B cell epitope of African swine fever virus NP419L protein and application

The invention belongs to the field of biological immunity, and discloses a linear B cell epitope of African swine fever virus NP419L protein and application. The epitope sequence shows good immunoreactivity through ASFV positive pig serum recognition verification. The African swine fever positive serum can be identified by using the B cell epitope identified by the invention to carry out ELISA (Enzyme-Linked Immunosorbent Assay) experiment, and the sensitivity of the African swine fever positive serum is superior to that of NP419L protein full length and other truncated fragments. The epitope identified by the invention has high conservative property in reference ASFV strains in a plurality of popular regions in China, and has wide universality and adaptability. The kit can be widely applied to etiological diagnosis, serological diagnosis, immunological detection and disease prevention and treatment of African swine fever viruses, and can be applied to preparation of African swine fever vaccines, pathogenesis research and the like.
Owner:HUAZHONG AGRI UNIV

Arthrobacter HJ1 for preventing and treating rhizoma polygonati root rot and application of arthrobacter HJ1

PendingCN121362687ABiocideBacteriaBiotechnologyArthrobacter
The invention provides arthrobacter HJ1 for preventing and treating fungal root rot of polygonatum sibiricum and application of the arthrobacter HJ1, and belongs to the technical field of disease prevention and treatment. The preservation number of the arthrobacterium HJ1 is CCTCC (China Center For Type Culture Collection) NO: M20251843 The arthrobacter HJ1 has a remarkable inhibition effect on the pathogenic bacterium fusarium oxysporum of the rhizoma polygonati root rot. The arthrobacter HJ1 has a remarkable inhibition effect on the rhizoma polygonati root rot under an in-vitro condition, and can remarkably reduce scab expansion of the rhizoma polygonati root rot caused by fusarium oxysporum. In a field test, by using the arthrobacter HJ1, the morbidity of the rhizoma polygonati root rot can be remarkably reduced, and the control effect on the rhizoma polygonati root rot is improved. A safety test shows that the arthrobacter HJ1 has no adverse effect on the growth of the polygonatum sibiricum and can be safely used for preventing and controlling root rot fungal diseases of the polygonatum sibiricum. The arthrobacter HJ1, as a beneficial biocontrol bacterium for polygonatum sibiricum root rot fungal diseases, is of great significance to healthy and green development of the polygonatum sibiricum industry.
Owner:INST OF CHINESE MATERIA MEDICA HUBEI ACAD OF AGRI SCI

Bird's nest peptide with anti-aging function and application thereof

The invention discloses cubilose peptide with an anti-aging function and application of the cubilose peptide. The amino acid sequence of the cubilose peptide is TFSLCEICETMVK. The cubilose peptide disclosed by the invention can resist aging, prevent diseases, beautify and protect skin, and improve the immunity of the organism, and has important significance in developing the efficacy of cubilose, improving the economic value of cubilose and expanding the application of the cubilose peptide.
Owner:BEIJING RONGSHUTANG BIOTECHNOLOGY CO LTD +1

Composite agent for preventing and treating diseases and insect pests of forest trees and preparation method of composite agent

The invention discloses a composite agent for preventing and treating forest diseases and insect pests and a preparation method thereof, and relates to the technical field of forest disease and insect pest prevention and treatment. The composite agent is composed of a natural active extract, a synergistic auxiliary agent and a repair conditioning agent, the natural active extract comprises a melia azedarach fruit-leaf extract, a camellia seed meal extract, a pinus massoniana needle leaf extract and a camphor tree bark extract, and the composite agent has broad-spectrum insecticidal and bacteriostatic effects; a tea residue modified penetrant and early indica rice starch sustained-release microspheres are adopted as the synergistic auxiliaries, so that the adhesiveness and infiltration capacity of the pesticide on waxy leaves are remarkably improved, and long-acting sustained release of active ingredients is realized; the restoration regulator is moso bamboo vinegar, can promote the growth of new shoots of trees and the synthesis of chlorophyll, and enhances the stress resistance of the trees. All the components are synergistically prepared through a green process, the combined effect of multiple components is fully played, insect and disease prevention, long lasting period and ecological restoration integration are achieved, and an efficient and ecologically compatible novel plant protection technical scheme is provided for forest health management and sustainable development.
Owner:JINAN STATE-OWNED LIUBU FOREST FARM

A hydroponic root-inducing method for Citrus reticulata and its supporting nutrient solution and application.

This invention relates to a hydroponic root-inducing method for *Cinnamomum camphora*, characterized by the following steps: plant pretreatment; hormone-induced root treatment; perlite substrate for root induction transition; mist-controlled humidification environment for root induction; hydroponics; and disease prevention. The hydroponics includes: hydroponics in clean water until secondary lateral roots of a predetermined length are formed, followed by nutrient solution cultivation; the nutrient solution is supplied using a gradient approach. This invention's hydroponic root-inducing method employs a synergistic model of hormone-induced root induction, perlite fixation, and a high-humidity environment, significantly improving the success rate of root induction and avoiding the mortality problem caused by direct hydroponics. Through gradient acclimatization with nutrient solution concentrations, it significantly reduces the incidence of early root tip necrosis and root rot, improving survival rate and root vitality.
Owner:FOSHAN UNIVERSITY

Application of rice E3 ubiquitin ligase OsCOP1 in rice virus resistance

The invention relates to application of RING type rice E3 ubiquitin ligase OsCOP1 in prevention and control of rice virus diseases, and belongs to the field of plant genetic engineering technology and disease prevention and control.
Owner:NINGBO UNIV

Diabetic foot prevention system and method based on immersive experience and artificial intelligence

The invention discloses a diabetic foot prevention system and method based on immersive experience and artificial intelligence, and relates to the technical field of disease prevention, and the diabetic foot prevention system comprises an immersive interaction module, a multi-sensory stimulation module, a physiological monitoring module, an artificial intelligence module and a disease intervention module. The interactive 3D virtual scene is constructed through the immersive interaction module, the pathological evolution process of the diabetic foot is visually displayed, the problem that disease development is difficult to truly present in a traditional science popularization mode is solved, a diabetic patient is helped to deeply understand the pathogenesis, the evolution stage and the potential consequence of the disease, and the development of the diabetic foot is promoted. The foot disease state of the diabetic foot patient is simulated through the multi-sensory stimulation module, so that the diabetic patient experiences real symptoms such as pain and burning feeling, the fluke mind of the diabetic patient is broken, the foot health is actively concerned, and the diabetic foot risk is improved. And the risk of delay of the intervention opportunity due to light diseases is reduced.
Owner:THE AFFILIATED CENT HOSPITAL OF DALIAN UNIV OF TECH (DALIAN CENT HOSPITAL)

A method for analyzing and processing gene microarray data

The application discloses a kind of gene microarray data analysis processing methods, it is related to biomedical information processing technical field, comprising: using microarray technology, obtain gene expression data;Multiple low-dimensional feature selection tasks are constructed;Optimal feature subset is obtained by multi-task pseudo-affine transformation algorithm;According to optimal feature subset, neural network model is trained;Analysis processing is carried out to the gene to be predicted and whether it is predicted to be ill.The gene microarray data analysis processing method of the application is analyzed to gene microarray data characteristics, and gene microarray data is helpful to dig disease characteristic gene information, and has a key role to early detection, clinical treatment and disease prevention of disease.
Owner:SHANDONG UNIV OF SCI & TECH