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962 results about "Disease prevention" patented technology

Intelligent disease early warning system for aquaculture environment and storage medium

The invention belongs to the technical field of aquaculture automation control, and particularly discloses an aquaculture environment intelligent disease early warning system and a storage medium, the system comprises a data acquisition layer, a data transmission layer, a processing platform layer and an application service layer; the data acquisition layer comprises an environment monitoring unit, a water quality sensor group, portable detection equipment and a data acquisition module; the data transmission layer comprises a wireless transmission module and an edge computing node; the processing platform layer comprises a machine learning prediction model and an environment factor correlation analysis model; the application service layer comprises an early warning information push module and a prevention and control scheme generation module. According to the intelligent disease early warning system for the aquaculture environment and the storage medium, a correlation model of environmental factors and disease occurrence is innovatively established, the early warning accuracy is 85% or above by adopting a machine learning technology, comprehensive monitoring and real-time early warning in the aquaculture process can be achieved, and accurate and efficient disease prevention and control are supported.
Owner:SOUTH CHINA NORMAL UNIV +1

Crop growth prediction system and method based on agricultural unmanned aerial vehicle remote sensing technology

The invention discloses a crop growth prediction system and method based on an agricultural unmanned aerial vehicle remote sensing technology, and relates to the technical field of agricultural information and intelligent monitoring, the system uses an unmanned aerial vehicle remote sensing module and a ground Internet of Things sensor module to collect multi-source data of banana planting, fish pond breeding and hog house breeding, and the multi-source data is used as a data expression recording carrier. The edge computing node module preprocesses data, and the cloud intelligent platform module is internally provided with a multi-modal data fusion model, a growth prediction model and the like as processing record carriers to realize data depth analysis and prediction. And realizing automatic control of the production process according to the data through block chain evidence storage and the intelligent contract. And constructing a disease prevention and control model by using the hyperspectral image of the unmanned aerial vehicle and related data. According to the invention, the collection, processing and application capabilities of agricultural production data are improved, accurate prediction and intelligent regulation are realized, the resource utilization efficiency is improved, the disease loss is reduced, and the agricultural intelligent development is promoted.
Owner:ZHEJIANG UNIV

Intelligent pest and disease damage identification and targeted spraying method and system based on machine vision

The invention discloses an intelligent pest and disease damage identification and targeted spraying method and system based on machine vision, and the method comprises the steps: inputting a multispectral image sequence and environment sensing data into a processing system, and obtaining a high-quality fusion image through spectrum-space joint correction and environment adaptive compensation; constructing a region growing algorithm based on a topological flow theory, and realizing accurate extraction of a target region in combination with curvature flow boundary optimization; integrating the spatial features, the time sequence features and the context information by adopting a multi-modal feature fusion method, and establishing a pest state evaluation and behavior prediction model; and according to an evaluation result, a spraying track is optimized through an environment constraint field, a self-adaptive parameter control system is adopted to adjust spraying parameters, and closed-loop optimization is realized through real-time monitoring. The technical problems of low pest and disease identification precision, poor spraying effect and the like in a complex environment are solved, and the accuracy and efficiency of prevention and treatment are improved.
Owner:JIANGSU KUNYUN INTERNET TECH GRP CO LTD

Intelligent blueberry disease detection method and system based on multi-mode unsupervised learning

The invention is suitable for the technical field of agricultural intellectualization, and provides an intelligent blueberry disease detection method and system based on multi-modal unsupervised learning, and the method comprises the following steps: carrying out the feature extraction and clustering of preprocessed multi-modal data based on an adaptive contrast deep clustering framework, and obtaining a feature extraction result; obtaining a multi-modal preliminary feature and a preliminary clustering result; based on a multi-modal complementary feature fusion mechanism, according to the multi-modal preliminary features and the preliminary clustering result, carrying out adaptive weighted fusion on the multi-modal preliminary features to obtain multi-modal fusion features; performing unsupervised clustering optimization and disease type identification on the multi-modal fusion features to obtain an unsupervised learning model; and performing deployment and incremental learning on the unsupervised learning model, and detecting the blueberry diseases. According to the method, early-stage accurate detection of blueberry diseases is realized through an unsupervised learning algorithm, a new normal form is provided for intelligent accurate management of blueberries, and the disease prevention and control efficiency and industrial economic benefits are effectively improved.
Owner:CHANGCHUN NORMAL UNIV

Tomato disease diagnosis method based on multi-modal data analysis

The invention relates to the technical field of intelligent agricultural equipment, in particular to a tomato disease diagnosis method based on multi-modal data analysis, which comprises the following steps of: 1, synchronously acquiring and preprocessing multi-modal data, synchronously triggering a hyperspectral imaging device and a microscopic camera, respectively acquiring a plant canopy hyperspectral image and a stem microscopic image, and acquiring a plant canopy hyperspectral image and a stem microscopic image; meanwhile, temperature, conductivity and dissolved oxygen environment parameters are continuously collected in the root zone; 2, self-adaptive feature extraction and fusion in the growth stage are carried out, reflectivity correction and leaf segmentation are carried out on the hyperspectral image, and leaf surface spectrum curve features are extracted; step 3, hybrid model construction and space-time analysis: constructing a hybrid model comprising spectrum, microscopy and environment analysis networks, and dynamically adjusting each network weight through a gating network; and 4, generating a disease decision. The method can realize accurate, efficient and real-time tomato disease diagnosis, has high practical value, and can effectively improve the disease prevention and control capability in agricultural production.
Owner:CHAOHU LUOXIANG AGRICULTURAL DEVELOPMENT CO LTD

Mortierella alpina strain and application thereof in plant growth promotion, disease prevention and soil improvement

The invention relates to the field of microorganisms, in particular to a mortierella alpina strain MA with a plant growth promoting function and application of the mortierella alpina strain MA. The strain has remarkable nitrogen fixation, siderophore production, auxin (IAA) production and cellulase activity, can inhibit various soil-borne pathogenic bacteria such as phytophthora capsici and fusarium, and remarkably improves the disease resistance and growth performance of crops such as pepper. The strain has various functions and broad-spectrum action, is suitable for replacing part of chemical fertilizers and pesticides in intensive agriculture, and realizes green and efficient planting of crops.
Owner:YUNNAN AGRICULTURAL UNIVERSITY

Shrimp health status early warning method and system based on water quality monitoring

The invention discloses a shrimp health state early warning method and system based on water quality monitoring, and aims to improve the disease prevention and control efficiency in a shrimp culture process. The method comprises the following steps: collecting historical breeding disease data and water quality change data of a target shrimp breeding water area, and constructing a water quality pathopoiesis knowledge graph; then water quality change data in a preset monitoring time period is obtained, space-time tracing is carried out by using the water quality change prediction model, and a water quality anomaly propagation path diagram is generated; formulating a water quality monitoring strategy based on the propagation path diagram, and optimizing the layout and frequency of monitoring points; and finally, monitoring the water quality in real time according to the established monitoring strategy, and realizing dynamic early warning of the health state of the prawns by combining real-time monitoring data and a water quality pathopoiesis knowledge graph. Water quality related diseases can be effectively prevented and controlled, and the stability and yield of shrimp culture are improved.
Owner:海南省水产品质量安全检测中心

Intelligent pest and disease damage monitoring system based on multi-modal data fusion of unmanned aerial vehicle

The invention discloses an intelligent pest and disease damage monitoring system based on multi-modal data fusion of an unmanned aerial vehicle, and the system carries a multi-source heterogeneous data collection module through the unmanned aerial vehicle, obtains optical, multispectral, thermal infrared and other multi-modal data in parallel, and stores the data in a ground end after wireless link coding transmission and format adaptation. According to the system, an improved YOLO algorithm is used to construct a multi-level feature pyramid and an adaptive convolution kernel architecture, and feature extraction and disease and pest candidate region generation are carried out on multi-modal data; time sequence dynamic analysis and depth feature mining are realized by means of an optimized long-short-term memory network in combination with parameters such as a pest and disease damage growth cycle; and through a weight adaptive adjustment fusion strategy, decision-level fusion is carried out on results of the two algorithms, and final monitoring data is output. Besides, various correlation formulas are designed in each link of the system, so that parameters in multiple aspects of data acquisition, algorithm processing and the like are mutually coordinated, efficient and accurate monitoring of diseases and insect pests is realized, and technical support is provided for prevention and control of agricultural diseases and insect pests.
Owner:DEYANG JINONG AGRI TECH CO LTD

Layout image generation method and device, computer equipment and storage medium

The invention relates to a layout image generation method and device, computer equipment and a storage medium, and the method comprises the following steps: carrying out the element analysis of original image data, and obtaining image element information; performing feature extraction on the image element information to obtain image features and text features; performing hypergraph structure construction according to a preset design rule, the image features, the text features and the image element information to obtain hypergraph structure information; performing style parameter adjustment and coordinate adjustment on the hypergraph structure information according to the matching similarity corresponding to the element embedding vector to obtain to-be-rendered information; and performing image layout rendering according to the to-be-rendered information to obtain an effective layout image. The method can be applied to application scenes of financial science and technology and digital medical systems, and insurance product propaganda images or disease prevention propaganda images which effectively express image elements and features can be effectively, accurately and quickly generated according to original insurance product images or health education images in the system.
Owner:PING AN TECH (SHENZHEN) CO LTD

Tilletia controversa Kuhn effect protein g16561 and application thereof

The invention belongs to the field of prevention and treatment of tilletia controversa Kuhn, and particularly relates to a tilletia controversa Kuhn effect protein g16561 and application thereof. An amino acid sequence of the Tilletia controversa Kuhn effect protein is shown as SEQ ID NO: 2. The effect protein plays an important role in the process of inhibiting plant defense reaction, and has an interaction relationship with a wheat protein in the process of infecting wheat by Tilletia controversa Kuhn. According to the invention, the pathogenesis of Tilletia controversa Kuhn can be deeply researched, and the excavation of wheat disease-resistant genes and the cultivation of wheat disease-resistant varieties can be promoted.
Owner:SANYA NATIONAL INSTITUTE OF SOUTHERN BREEDING CHINESE ACADEMY OF AGRICULTURAL SCIENCES +2

Burkholderia and application thereof in prevention and treatment of eucalyptus blight

The invention discloses a Burkholderia sp. Strain and an application thereof in prevention and treatment of eucalyptus blight. The Burkholderia sp. AS-SF-1 disclosed by the invention has the preservation number of GDMCC (Graphical December Microorganism Center) No. 66223; the culture and volatile matter of the strain can inhibit growth of various forest pathogenic bacteria, the eucalyptus has a remarkable control effect on branch blight, siderophore can be generated, absorption and utilization of iron can be promoted, various types of carbon sources or nitrogen sources can be utilized, and the strain can grow within the pH range of 4-9. The burkholderia sp. AS-SF-1 disclosed by the invention has an important application value on planting of eucalyptus and prevention of diseases.
Owner:GUANGDONG ECO ENGINEERING POLYTECHNIC +1

Toxoplasma gondii attenuated vaccine strain RHdeltarop67 as well as construction method and application thereof

The invention discloses a toxoplasma gondii attenuated vaccine strain RH delta rop67 as well as a construction method and application thereof, and belongs to the technical field of parasitic disease prevention and control and biological product preparation. The attenuated vaccine strain is constructed by performing targeted knockout on the ROP67 gene in a toxoplasma gondii strain RH delta ku80 through a CRISPR / Cas9 mediated gene editing technology. Compared with a wild type strain, the attenuated vaccine strain shows remarkable attenuation characteristic and good immunogenicity. A test result shows that the attenuated vaccine strain can induce a host to generate specific immune response mainly based on cellular immunity, maintains a protection effect on toxoplasma gondii infection in a relatively long immune period, and has a protection effect on tachyzoite infection and a chronic infection stage of toxoplasma gondii strains with different virulence; the survival ability of a host to tachyzoite infection can be improved, and the formation level of cysts in tissues is reduced. The invention provides a technical scheme with long-term immune potential for research and development of toxoplasma gondii attenuated vaccines.
Owner:SHANXI AGRI UNIV

Microbial agent and application thereof in prevention and treatment of rice blast and promotion of rice growth

The invention discloses a microbial agent and application thereof in preventing and treating rice blast and promoting rice growth, active ingredients of the microbial agent are formed by compounding cold bacillus with the preservation number of CGMCC (China General Microbiological Culture Collection Center) NO: 33492 and bacillus velezensis with the preservation number of CGMCC NO: 33493, and the microbial agent aims at solving the synergistic problem of preventing and treating rice blast and promoting rice growth. According to the complex microbial inoculant, through the synergistic interaction between the two strains, the metabolite of the complex microbial inoculant can completely inhibit the spore germination of magnaporthe oryzae; meanwhile, the fungicide can degrade cellulose, obviously promote the growth of plant height, fresh weight and dry weight of rice, and realize the integration of disease prevention and growth promotion. The invention further discloses a preparation method of the fungicide and an application method of the fungicide for preventing and treating rice blast and promoting growth in a root irrigation mode in the three-leaf stage of rice. The microbial agent disclosed by the invention has dual functions of efficiently preventing diseases and stably promoting growth, and an efficient and safe biological solution is provided for green and sustainable development of agriculture.
Owner:SHENYANG AGRI UNIV

Method for predicting and judging diarrhea risk grade of suckling piglet

The invention discloses a method for predicting and judging the diarrhea risk grade of suckling piglets, and belongs to the technical field of piglet epidemic disease prevention and control. Aiming at the problems that traditional piglet diarrhea prediction depends on manual observation, multi-dimensional data relevance is insufficient, early warning lags and the like, a multi-parameter monitoring device is arranged in a piglet breeding environment to collect environment data in real time, and an excretion behavior detection module is used for triggering an excrement image collection device to obtain a high-quality image; and inputting multi-source data into a random forest model for risk level prediction by combining regular weight measurement and blood detection in a specific time period after environment adjustment. The system dynamically adjusts pig environment parameters according to a prediction result, after spraying, heating compensation is started to maintain humidity and control ammonia concentration, and closed-loop feedback regulation is formed. According to the method, through multi-modal data fusion and model iterative optimization, early-stage accurate early warning of diarrhea risks is realized, the method is suitable for intelligent management of a large-scale pig farm, the diarrhea occurrence rate can be effectively reduced, and the breeding benefits are improved.
Owner:GUANGXI NONGKEN YONGXIN ANIMAL HUSBANDRY GRP XINXING CO LTD

Monoclonal antibody pair for detecting feline immunodeficiency virus p24 protein and application thereof

The application belongs to the technical field of biological detection, and particularly relates to a monoclonal antibody pair for detecting feline immunodeficiency virus p24 protein and application thereof. The monoclonal antibody pair is monoclonal antibody 1D8 and monoclonal antibody 1H10, which can specifically recognize feline immunodeficiency virus p24 protein, and the heavy chain and light chain variable region complementarity determining region sequences of 1D8 and 1H10 are clear, and are respectively shown as SEQ ID NO. 1-12. The antibody pair can effectively avoid cross reaction, and significantly improve the accuracy and sensitivity of detection; the colloidal gold detection test strip constructed based on the antibody pair is simple and fast in operation, is suitable for early antigen detection of FIV infection, solves the problem that existing antibody detection cannot distinguish natural infection and vaccine immunization, and provides a reliable technical means for on-site screening and disease prevention and control of FIV.
Owner:BEIJING SUBENYUANHE BIOTECHNOLOGY CO LTD

Railway subgrade frost heave disease prevention and control system and method adapted to severe cold climates

The present invention discloses a system and method for preventing and controlling frost heave damage in railway subgrades adapted to severe cold climates. This system belongs to the field of seasonal frozen soil engineering technology. The prevention and control system includes several ground-source heat pump devices consisting of heating units, heating pipes, heat collecting pipes, and a detection assembly. Several heating units are arranged at the foot of the subgrade slope along the length of the railway. The heating pipes are laid in the frost heave development layer of the subgrade, and the heat collecting pipes are installed in the stable layers of the foundation on both sides of the subgrade. A heat carrier circulates through the pipeline consisting of the heating pipes, heating units, and heat collecting pipes. Temperature sensors, pressure sensors, and displacement sensors are used to monitor the subgrade freezing temperature, heat carrier temperature, compressor intake and exhaust pressures, and track deformation, respectively. A control assembly receives signals from the detection assembly and controls the operating mode of the heating units. The present invention ensures rapid compressor superheat establishment during startup in severe cold environments and rationally controls the compressor exhaust temperature range and operating mode during normal operation.
Owner:SHIJIAZHUANG TIEDAO UNIV

Small peptide NCRP246 and application thereof in improving resistance to corn southern leaf blight

The invention belongs to the field of corn disease prevention, relates to a novel small peptide, provides a small peptide NCRP246 and application thereof in improvement of corn southern leaf blight resistance, and provides feasibility for plant disease resistance by using non-classical peptides. A corn southern leaf blight resistance identification experiment proves that NCRP246 can significantly improve the resistance of corn to southern leaf blight, and further researches that the NCRP246 reduces oxidative damage of pathogenic bacteria infection of the southern leaf blight to the corn by reducing H2O2 accumulation so as to mediate the resistance of the corn to the southern leaf blight; the analysis from the molecular perspective proves that the NCRP246 can induce the expression of defense related genes.
Owner:HENAN AGRICULTURAL UNIVERSITY

Railway roadbed frost heaving disease prevention and control system and method adapting to severe cold climate

The invention discloses a railway roadbed frost heaving disease prevention and control system and method adapting to severe cold climate, and belongs to the technical field of seasonal frozen soil engineering.The prevention and control system comprises a plurality of ground source heat pump devices composed of heating units, heat supply pipes, heat collection pipes and detection assemblies, and the heating units are arranged at the slope toe position of a roadbed in the length direction of a railway; the heat supply pipe is laid on a frost heaving development layer of a roadbed, the heat collecting pipes are arranged on stable layers of the roadbed on the two sides of the roadbed, and the heat-carrying agent circularly flows in a pipeline composed of the heat supply pipe, the heating unit and the heat collecting pipes. A temperature sensor, a pressure sensor and a displacement sensor are used for monitoring the roadbed freezing temperature, the heat-carrying agent temperature, the suction and exhaust pressure of a compressor and the deformation amount of a track; and the control assembly receives a signal of the detection assembly and controls the operation mode of the heating unit. According to the method, rapid establishment of the superheat degree of the compressor in the starting stage in the severe cold environment and reasonable control over the exhaust temperature range and the operation mode of the compressor in the normal operation stage can be guaranteed.
Owner:SHIJIAZHUANG TIEDAO UNIV

Prevention and treatment method for apple alternaria leaf spot

The invention provides a control method for apple alternaria leaf spot, and belongs to the technical field of crop disease control. The prevention and treatment method comprises the following steps: spraying a foliar biological pesticide fertilizer to apple trees; the foliar biological medical fertilizer comprises a bacillus fermentation product and a trichoderma fermentation product, the bacillus is at least one of bacillus amyloliquefaciens TS-1203, bacillus subtilis B1 and bacillus subtilis BS-1208, and the bacillus is at least one of bacillus amyloliquefaciens TS-1203, bacillus subtilis B1 and bacillus subtilis BS-1208; the trichoderma is at least one of T6 and Ym. The combined action of bacillus and trichoderma is utilized, the morbidity of apple alternaria leaf spot can be effectively reduced, the growth of apple trees can be promoted, the photosynthetic capacity is improved, the combination of disease prevention and yield increase is realized, and the method is environment-friendly and suitable for green agricultural development.
Owner:GANSU AGRI UNIV

Disease-preventing root-promoting microbial agent containing soybean phospholipid as well as preparation method and application of disease-preventing root-promoting microbial agent

The invention discloses a soybean phospholipid disease-preventing and root-promoting microbial agent as well as a preparation method and application thereof, and belongs to the technical field of microorganisms. The microbial agent comprises a microbial composition, modified enzymolysis soybean phospholipid, a carrier and auxiliary components. According to the invention, the modified enzymolysis soybean phospholipid and microorganisms are combined to achieve a synergistic effect. According to the method, soybean phospholipid is modified and subjected to enzymolysis, and the steps of pretreatment, stepped low-temperature treatment, enzymolysis treatment, enzyme inactivation and purification and the like are carried out, so that the quality and performance of the soybean phospholipid are improved, the rhizosphere colonization rate of strains can be increased, the disease prevention and root promotion effects can be improved, the soil micro-ecological environment can be improved, and good growth conditions are created for plant root systems; and the disease-preventing and root-promoting effects of the microbial agent are further enhanced. The microbial agent disclosed by the invention can be used for remarkably reducing the morbidity of wheat sharp eyespot and reducing the use amount of chemical pesticides, can also be applied to planting of other crops, and can play a role in preventing and controlling various plant diseases and promoting root growth.
Owner:SHANDONG ZHIZHIYUAN ECOLOGICAL ENG CO LTD +1

Facility vegetable cultivation environment intelligent regulation and control system based on Internet of Things and multi-objective optimization algorithm

The invention relates to the technical field of intelligent agriculture and agricultural engineering, and particularly provides a facility vegetable cultivation environment intelligent regulation and control system based on the Internet of Things and a multi-objective optimization algorithm. The system comprises a blade microenvironment dynamic sensing subsystem which outputs and generates a blade boundary layer diffusion resistance-wind speed-temperature gradient real-time data set with space coordinates, namely a microenvironment state map; the stomatal conductance collaborative optimization subsystem outputs and generates an optimal airflow parameter combination packet which comprises a target wind speed vector, a temperature gradient threshold value and an expected stomatal conductance gain; and the bionic fluid tissue execution subsystem converts the optimal airflow parameter combination packet into a non-uniform airflow field, and microenvironment reconstruction is realized through a dynamic tuyere array. According to the method, the spanning of the facility environment regulation and control scale from the traditional greenhouse macroscale to the leaf micron scale is realized, the environment regulation and control precision is improved by 2-3 orders of magnitude, and a novel environment control normal form with both the disease prevention effect and the yield increasing potential is provided for facility vegetable production.
Owner:ANHUI TIANQIN AGRI TECH CO LTD

Disease monitoring and preventing system for goose breeding based on big data

The invention discloses a disease monitoring and preventing system for goose breeding based on big data, and relates to the technical field of poultry breeding monitoring. The system comprises a sensing front end, a storage end and a big data processing end, the big data end comprises an individual health monitoring module, a group behavior recognition module and a comprehensive evaluation patrol module; individual health monitoring and group behavior recognition are carried out on the goose house, and comprehensive analysis is carried out by combining output results of the individual health monitoring and the group behavior recognition to plan a goose house inspection route, so that omnibearing perception and intelligent analysis of the environment, physiology and behaviors of the goose house are realized, weak physiological or behavior abnormalities can be captured in the early stage of a disease; and the operation and maintenance cost and the computing power occupation are obviously reduced through dynamic inspection route optimization and intermittent sampling, so that the epidemic disease prevention and control efficiency and the production safety of the goose farm are comprehensively improved.
Owner:SHANDONG TIANGE AGRI & ANIMAL HUSBANDRY DEV CO LTD

Infection dynamic visualization evaluation method based on multi-modal data fusion

The invention relates to a multi-modal data fusion-based infection dynamic visualization evaluation method, which comprises the following steps of: acquiring multi-modal data which comprises a medical image modal, a microbiological modal, a spatio-temporal behavior modal and a physiological and biochemical modal; the multi-modal data is quickly searched through quantum parallel computing, and an optimal feature combination is obtained; carrying out fusion association on the optimal feature combination to obtain fusion features, and constructing a space-time coupling infection risk model at the same time; the space-time coupling infection risk model performs risk field construction based on the fusion features, and generates infection dynamic visualization content; compared with traditional single-mode data, the infection direction can be evaluated more accurately, after quantum calculation is introduced, the operand can be reduced, the calculation efficiency and the accuracy of optimal feature combination obtaining can be improved at the same time, the pathogen propagation path can be visually checked through the infection dynamic visualization content generated through the space-time coupling infection risk model, and the infection risk can be effectively improved. Therefore, blocking can be timely cut off, and disease prevention and control are achieved.
Owner:GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE HAINAN HOSPITAL

Bactericidal composition containing WML-01 and triazole compound as well as preparation and application thereof

The invention discloses a bactericidal composition containing WML-01 and a triazole compound, and is characterized in that the bactericidal composition is composed of the WML-01 and the triazole compound, and the mass ratio of the WML-01 to the triazole compound is (10: 1)-(1: 10). The bactericidal composition taking the WML-01 and the triazole medicament as effective components has a synergistic effect on prevention and treatment of rice bakanae disease, wheat stem rot, wheat scab, plant root rot and sclerotinia rot of colza, can effectively improve the disease prevention and treatment effect, reduces the pesticide consumption, delays the occurrence of drug resistance, improves the crop yield, and has a good application prospect. The method is safe, effective and economical, and has a wide market application prospect.
Owner:CHINA AGRI UNIV SANYA RES INST +1

Method for generating traditional Chinese medicine personalized nursing scheme for preventive treatment of diseases

The invention relates to the technical field of traditional Chinese medicine nursing or health improvement, in particular to a method for generating a traditional Chinese medicine personalized nursing scheme for preventive treatment of diseases. The method comprises the following steps: firstly, screening out all initial reference individuals of a current individual based on a similar condition between corresponding physique information of the individuals; further determining all concerned symptoms and corresponding concerned coefficients of the current individual according to the universality and change condition of each symptom of the current individual in the initial reference individual; screening out all reference individuals according to the attention coefficient of the common attention symptom of the current individual and each initial reference individual; and finally, generating a personalized nursing scheme of the current individual based on the nursing schemes of all the reference individuals. According to the method and the device, the reference individuals capable of providing similar nursing references are accurately screened out from the historical disease prevention individuals based on the similar physical conditions of the individuals and the similar conditions of the symptoms which are mainly concerned during nursing, so that the generation effect of the personalized scheme of the current individual is improved.
Owner:ZHONGJIANG COUNTY PEOPLES HOSPITAL

A vector, kit and application for long-acting gene knockdown of animal parasitic nematodes

The application discloses a kind of carrier, kit and application for long-acting gene knockdown of animal parasitic nematode, belong to the field of animal parasitic disease prevention and control.The lentivirus vector in the application integrates specific coding sequence to the genome of the infected nematode, stably and continuously expresses short hairpin RNA (shRNA) in the nematode, efficiently produces primary single-stranded small RNA (siRNA), these siRNAs target homologous target gene mRNA to cause its degradation, realize stable and continuous gene silencing effect.The application breaks through the bottleneck of traditional animal parasitic nematode RNA interference (RNAi) technology with low efficiency and instability, significantly improves the timeliness of conventional RNAi, can be used to establish long-acting RNAi technology system of animal parasitic nematode, has application value in the research of host in vivo process such as nematode infection, parasitism and pathogenicity and animal parasitic nematode disease prevention and control.
Owner:ZHEJIANG UNIV

Application of PGRN in preparation of product for preventing and treating neuropsychiatric disorder related diseases caused by estrogen deficiency

PendingCN120392967ANervous disorderPeptide/protein ingredientsDiseaseDuring menopause
The invention discloses application of PGRN in preparation of products for preventing and treating neuropsychiatric disorder related diseases caused by estrogen deficiency. The invention provides an application of a PGRN protein or a coding gene thereof or a virus expressing the coding gene thereof in preparation of a product with any one of the following functions: 1) preventing or treating or saving neuropsychiatric disorder related diseases caused by estrogen deficiency; 2) preventing or treating perimenopausal anxiety and / or depression symptoms; and 3) relieving anxiety-like behaviors and / or depression-like behaviors caused by estrogen deficiency. The application proves that the PGRN can play a role in protecting neuron damage caused by estrogen deficiency by rescuing CTSD enzyme activity and an autophagy pathway, and prompts that related medicines and measures influencing secretion and content of the PGRN can treat perimenopausal anxiety and depressive symptoms; and a new target and a new idea are provided for clinical treatment and drug development of anxiety and depression symptoms of climacteric women.
Owner:PEKING UNIV

Monoclonal antibody pair for detecting cat immunodeficiency virus p24 protein and application thereof

The invention belongs to the technical field of biological detection, and particularly relates to a monoclonal antibody pair for detecting cat immunodeficiency virus p24 protein and application of the monoclonal antibody pair. The monoclonal antibody pair is a monoclonal antibody 1D8 and a monoclonal antibody 1H10 and can specifically recognize cat immunodeficiency virus p24 protein, and sequences of complementary determining regions of variable regions of a heavy chain and a light chain of the 1D8 and the 1H10 are clear and are respectively shown as SEQ ID NO.1-12. The antibody pair can effectively avoid cross reaction, and the accuracy and sensitivity of detection are remarkably improved; the colloidal gold test strip constructed on the basis of the antibody pair is simple, convenient and rapid to operate, is suitable for early antigen detection of FIV infection, solves the problem that natural infection and vaccine immunity cannot be distinguished in existing antibody detection, and provides a reliable technical means for FIV field screening and disease prevention and control.
Owner:BEIJING SUBENYUANHE BIOTECHNOLOGY CO LTD

Application of acacetin in preparation of medicine for preventing and treating white spot syndrome

The invention belongs to the technical field of disease prevention and treatment and aquaculture, and relates to application of acacetin in preparation of a medicine for preventing and treating white spot syndrome. The invention discloses that the acacetin has the biological activity of resisting the white spot syndrome virus for the first time, verifies that the acacetin can obviously inhibit the replication of the white spot syndrome virus in the procambarus clarkia body, and simultaneously improves the survival rate of the procambarus clarkia infected by the white spot syndrome virus. The acacetin has a good antiviral effect on the white spot syndrome virus in crustacean aquaculture, and can be applied to prevention and treatment of aquatic animal diseases caused by the white spot syndrome virus.
Owner:SHENZHEN RESEARCH INSTITUTE OF NORTHWEST A & F UNIVERSITY

Heart disease occupational health risk assessment system based on RF-MLP model

The invention relates to a heart disease occupational health risk assessment system based on an RF-MLP model, and belongs to the technical field of health risk prediction. In order to solve the problem that prediction performance is limited due to the fact that an existing method is insufficient in the aspects of feature selection and model optimization, the invention provides a collaborative prediction scheme fusing recursive feature elimination (RFE), a random forest (RF) and a multi-layer perceptron (MLP). According to the technical scheme, the method comprises the steps that a data collecting and preprocessing module cleans and normalizes physiological indexes; the feature selection module calculates feature importance scores through an RFE-RF algorithm to screen key indexes; the random forest optimization module constructs a decision tree cluster; the MLP module is used for realizing nonlinear mapping through ReLU and Sigmoid functions; and the model fusion module integrates the output of the double models to generate final prediction. The system remarkably improves the prediction precision and generalization ability, provides high-robustness support for early warning of heart diseases of occupational people, and promotes disease prevention to be converted from passive response to active intervention.
Owner:CHONGQING UNIVERSITY OF SCIENCE AND TECHNOLOGY