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54 results about "Fusion mechanism" patented technology

The fusion mechanism describes any mechanism by which cell fusion or virus-cell fusion takes place, as well as the machinery that facilitates these processes. Cell fusion is the formation of a hybrid cell from two separate cells. There are three major actions taken in both virus-cell fusion and cell-cell fusion: "1) dehydrate polar head groups, (2) promote a hemifusion stalk, and (3) open and expand pores between fusing cells." Virus-cell fusions occur during infections of several viruses that are health concerns relevant today. Some of these include HIV, Ebola, and Influenza. For example HIV infects by fusing with the membranes of immune system cells. In order for HIV to fuse with a cell, it must be able to bind to the receptors CD4, CCR5, and CXCR4. Cell fusion also occurs in a multitude of mammalian cells including gametes and myoblasts.

Polypeptides capable of inhibiting human coronavirus infections in a broad spectrum manner, and applications thereof

The present invention belongs to the field of biomedicine, and relates to polypeptides capable of inhibiting human coronavirus infections, particularly to polypeptides capable of inhibiting human coronavirus infections in a broad spectrum manner, and applications thereof. According to the present invention, the polypeptides capable of providing broad spectrum inhibition effects for infections caused by more than 2 human coronaviruses are provided based on the conservation property of the S2 region of a coronavirus S protein and the similar fusion mechanism; the test results show that the polypeptides can achieve the commonality of the human coronavirus, ie., the similar HR region and the same fusion mechanism mediated by the coronavirus S protein so as to provide a series of HCoV-EK polypeptides, wherein the polypeptides provide good inhibition effects for currently popular human coronaviruses, and further provide good inhibition activity for SARS virus (RsSHC014-CoV or RsW1V1-CoV) possibly infecting human; and the polypeptides of the present invention can provide the prevention and treatment candidate drug for the currently popular human coronaviruses and the novel human coronavirus possibly emerging in the future.
Owner:SHANXI JINBO BIO PHARMA CO LTD

Multi-strategy adaptive lane line detection method based on stereoscopic vision

The invention discloses a multi-strategy adaptive lane line detection method based on stereoscopic vision, and the method is based on the stereoscopic vision, and improves the robustness of a lane line detection task through the fusion of the three-dimensional depth information of a disparity map and the RGB semantic information of a two-dimensional image. In the detection stage, a road surface area is adaptively segmented by priori knowledge of three-dimensional environment information to serve as a lane line estimation area, obstacles which are not related to detection are filtered out, andthe problem of interference is solved. In the lane line extraction stage, RGB semantic information of a two-dimensional image is used, and a multi-strategy fusion mechanism and a sliding window technology in an image time domain are adopted to further eliminate interference of areas such as tree shadows, road signs and local fouling related to detection. A three-order Bezier curve model is adoptedin the lane line fitting process, and order characteristics of different lane lines can be better expressed. According to the method, the robustness of a vision-based lane line detection task is greatly improved, and the data point search speed and accuracy are improved.
Owner:BEIJING UNIV OF TECH

Wind turbine generator bearing fault diagnosing method based on deep joint adaptation network

The invention discloses a wind turbine generator bearing fault diagnosing method based on a deep joint adaptation network. The wind turbine generator bearing fault diagnosing method based on the deepjoint adaptation network comprises the following steps: 1), establishing a multi-element fusion database; 2), establishing a deep joint adaptation model; 3), establishing a wind turbine generator bearing fault diagnosing model of the deep joint adaptation network; 4), establishing a multi-GPU cluster computing system. With the wind turbine generator bearing fault diagnosing method, according to distribution difference characteristics between training data and target data during monitoring under different actual working conditions, an inter-domain invariant characteristic representing and probability distribution difference correcting mechanism is explored, a fault target recognition strategy based on an inter-domain joint distribution adaptation and common characteristic deep learning fusion mechanism is provided, advantages of a deep self-encoding network can be utilized, the characteristics are not required to be artificially selected, better, abstract and advanced characteristics can be automatically extracted, and the computational complexity of a classification algorithm is reduced; the wind turbine generator bearing fault diagnosing method is especially suitable for a multi-noise, large-data, complex-structure and dynamic system.
Owner:安赛尔(长沙)机电科技有限公司

Design method of multi-dimension attribute data oriented multi-layered clustering fusion mechanism

ActiveCN104933444ARealize the clustering of pros and consImprove data clustering performanceCharacter and pattern recognitionProbabilistic methodData set
The invention discloses a design method of a multi-dimension attribute data oriented multi-layered clustering fusion mechanism. The method comprises the following steps: 1) converting a data set into a matrix form, and preprocessing data; 2) according to data index attribute characteristics, extracting an optimal reference standard, and carrying out normalization processing on the data; 3) calculating a grey correlation degree, generating a similar matrix of the grey correlation degree, and then, carrying out grey correlation degree clustering to obtain a primary clustering result; 4) according to the primary clustering result in the step 3), adopting a rough set theory to establish a decision table system; 5) calculating an attribute significance information entropy of the decision system for each clustering member; 6) setting a weight for each clustering member; and 7) according to the calculated weight, adopting a probability method to calculate a probability of each data object in each class level to which the data object belongs, selecting the class level where the data object belongs to when the probability is highest to serve as the class level to which the data object belongs to, and obtaining a final clustering fusion result.
Owner:NANJING UNIV OF POSTS & TELECOMM

Information-fusion-mechanism-based multi-robot dangerous odor source positioning method

The invention relates to an information-fusion-mechanism-based multi-robot dangerous odor source positioning method. In the conventional methods, information is incompletely utilized, and communication constraints are not taken into account, so a multi-robot system may be locally convergent. The method provided by the invention comprises the following steps of: first establishing an information fusion matrix and an odor source position mean value distribution probability model, extracting mean value information, and storing the extracted mean value information into the information fusion matrix; then establishing odor source position probability distribution according to the mean value information, and extracting position information; and finally controlling robots to move to a target position by adopting spiral paths as motion trails of the robots based on probable positions and current position of an odor source, and continuously updating position information, corresponding to maximum concentration, obtained by the robot group and the position information, corresponding to the maximum concentration, obtained by individual robots until a given position is obtained. By the method,the multi-robot system can rapidly position the dangerous odor source, and effectively provide the probable positions of the dangerous odor source under the conditions of communication constraints.
Owner:扬州中规电机科技有限公司

Deep learning super-resolution method based on enhanced upsampling and discrimination fusion mechanism

The invention provides a deep learning super-resolution method based on an enhanced upsampling and discrimination fusion mechanism, which comprises the following steps of: directly extracting original features of a low-resolution input image by using a single layer based on a deep learning convolutional layer in a residual error branch; using 6 cascaded multi-layer feature fusion-based circular convolution units to extract deep features, and enabling the deep features output by each circular convolution unit to be subjected to up-sampling through 6 deconvolution layers; fusing the up-sampled high-resolution features by applying a feature fusion mode with a discrimination mechanism, and performing dimensionality reduction on the up-sampled features by using a single-layer convolutional layer to obtain a residual error of the high-resolution image; carrying out up-sampling on the low-resolution image by using a bicubic interpolation method in a mapping branch; and adding the mapping and the residual of the high-resolution image pixel by pixel to obtain a final high-resolution image. According to the invention, an up-sampling opportunity is provided for low-resolution characteristics of each stage, and higher reconstruction accuracy is obtained.
Owner:GUANGZHOU TUWEI NETWORK TECH

Vertebral fusion mechanism approached through minimally invasive pathway

ActiveCN107049565AThe size of the contact surface can be controlledTraumaSpinal implantsFusion mechanismInjection port
The invention relates to a vertebral fusion mechanism approached through a minimally invasive pathway. The vertebral fusion mechanism comprises a bag and a supporting material, wherein the bag can be folded or contracted; an injection port is formed in one end of the bag; the supporting material is injected into the bag from the injection port; the bag, which is under a full state, is represented as a columnar structure; the surfaces, getting into contact with upper and lower vertebral bodies, of the bag are vertebral body contact surfaces; a contractible limiting mechanism is arranged in a circumferential direction of the bag; the contractible limiting mechanism is less than or identical to the bag under the natural full state in diameter; and a cross section, perpendicular to the vertebral body contact surfaces, of the bag is represented as a transverse H-shaped structure or a rectangular structure when the bag is implanted into an intervertebral disc and the supporting material is injected. The problem of a fusion cage, which cannot control contact areas with upper and lower vertebral bodies, causes influence to a fusion effect of the upper and lower vertebral bodies since a bone grafting space is too small is solved; and the fusion mechanism can adapt to height of an intervertebral space in a non-level mode and can control the contact areas with the upper and lower vertebral bodies.
Owner:NINGBO HICREN BIOTECH

Support-free 3D printing machine

The invention discloses a support-free 3D printing machine. The support-free 3D printing machine comprises a supporting shell, wherein the supporting shell is connected to a power output component of an X-axis translating mechanism; a fusion mechanism which is used for fusing consumable items which enter the supporting shell, a multi-sprayer assembly and a power supply mechanism are further mounted in the supporting shell; the multi-sprayer assembly is used for spraying out the fused consumable items and has a function of switching over multiple sprayers; the power supply mechanism provides power for switching of the sprayers of the multi-sprayer assembly; connecting columns which are uniformly distributed in the peripheral direction at intervals and are connected with the sprayers are arranged on a rotary seat; a plane on which the central axes of the connecting columns are located and a plane on which the central axis of the rotary seat is located are base surfaces; an included angle between each two adjacent base surfaces is the same and is delta; a power output component of the power supply mechanism is connected with the rotary seat; the rotation angle of the driving rotary seat is an integral multiple of delta; and printing on an object in the horizontal direction can be realized, so that support-free printing of a suspension structure is realized.
Owner:泰州市龙泽环境科技有限公司

Welding mechanism of position punch fixture glue piece

The invention discloses a welding mechanism of a position punch fixture glue piece. The welding mechanism comprises the glue piece and an adhesive tape fusion mechanism and an impact mechanism, wherein a low-power speed regulated motor drive and a high-precision splitter drive are utilized in the glue piece and the adhesive tape fusion mechanism, a trimming die and a bottom die can carry out 360-degree peripheral and 90-degree slitting rotation operation; the impact mechanism is internally provided with a high-precision linear slide rail and a linear sliding block so as to enable the impact mechanism to achieve the switchover of a die cutting region and a heat seal region, and a cylinder is driven by die cutting so as to drive whole upper structure to ascend and descend; and when an ironware stamping die is in operate, the glue piece and the adhesive tape fusion mechanism bear the impaction of the impact mechanism, thereby finishing the precise punching process of various elastic and non-elastic adhesive tapes. The welding mechanism of the position punch fixture glue piece provided by the invention is used for fusing a fixture plastic glue piece and the adhesive table after elastic adhesive tape position punch is carried out; and the welding mechanism is especially suitable for product production processes such as punching and fusion of a TPU (Thermal Receiver Unit), punching and fusion of PVC (polyvinyl chloride) flexible glue, punching and fusion of EVA (ethylene-vinyl acetate) and the like.
Owner:SUZHOU HUARI JINLING MACHINERY

Network packet loss rate boundary characterization method under multiple-data stream fusion mechanism

InactiveCN105743813AReflect the need for key service qualityIn line with the principles of analysisData switching networksQuality of serviceService model
The invention relates to a network packet loss rate boundary characterization method under a multiple-data stream fusion mechanism. The method is characterized by comprising the steps of designing an arrival model, a service model and a corresponding boundary function on the basis of the distribution characteristics of flow backlog, modeling a coding node based on a fusion service mechanism, deriving the boundary function and the arrival curve of the node in a phased manner, and establishing the corresponding relationship between the system packet loss rate boundary performance on one hand and the system cache capacity, the data flow arriving the node, the service ability and the quality of service demand on the other hand based on the algebra theory under both conditions of full-fusion opportunity and no-fusion opportunity, thus getting the packet loss rate boundary performance under multiple-data stream fusion service. According to the invention, the arrival process and the service process are modeled based on a cumulative flow center arrival curve and a strict random service curve for the first time, and the behaviors and characteristics to which the two different random processes pay close attention are embodied. The method is more practical, and meets the needs of operating units for network configuration.
Owner:WUHAN TEXTILE UNIV

A task-driven multi-source information fusion method

The invention provides a novel task-driven multi-source information fusion method. Aiming at the characteristics of multi-platform and multi-sensor networking, a multi-thread information fusion mechanism is proposed, which can be adjusted automatically according to tasks. Firstly, based on multi-platform task planning, the transformation mapping from different application tasks to situation information requirements is realized by multi-objective decision-making method. Then, the real-time detection data quality of the sensor is evaluated based on the multi-source comprehensive verification comparison. The quality assessment results are generated based on the computing and communication resource allocation of sensor network and the situation, and the information fusion capability under thecurrent state is predicted. Finally, the multi-task dynamic scheduling method is used to generate the optimized information fusion threads under multi-constraint conditions, and the automatic matchingand adjustment of the corresponding fusion threads can be realized under the dynamic and changeable task conditions. This method can provide support for the generation of reasonable and applicable situation information for multiple application platforms under the background of diversified tasks.
Owner:NAVAL AVIATION UNIV +1
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