6 results about "Haemophilus" patented technology

The invention belongs to the technical field of biology, and particularly relates to a quintuple fluorescent PCR detection reagent for porcine respiratory pathogens and application of the quintuple fluorescent PCR detection reagent. The quintuple fluorescent PCR detection reagent disclosed by the invention can achieve the purpose of simultaneously identifying and detecting actinobacillus pleuropneumoniae, haemophilus parasuis, mycoplasma hyopneumoniae, pasteurella multocida and / or streptococcus suis, and has the advantages of simplicity, convenience and rapidness in operation, high accuracy, high sensitivity and good repeatability; the method has important significance on rapid and accurate detection and epidemic disease prevention and control of clinical porcine respiratory pathogens.

The invention relates to the technical field of biological detection, in particular to a nucleic acid combination product, a PCR premix, a method and a kit for identifying respiratory tract pathogenic bacteria. The nucleic acid combination product comprises a primer pair as shown in SEQ ID NO: 1 to SEQ ID NO: 21 and a probe. The invention provides a nucleic acid detection product for detecting klebsiella pneumoniae, streptococcus pneumoniae, haemophilus influenzae, pseudomonas aeruginosa, acinetobacter baumannii, staphylococcus aureus and moraxella catarrhalis, and the nucleic acid detection product can be used for performing amplification detection on conserved fragments of target pathogens in the same PCR reaction system, and is efficient and low in cost. Moreover, the anti-interference capability is strong, and the sensitivity is high.

This invention belongs to the field of microbial technology, specifically relating to an oral microorganism for identifying taste sensitivity, its identification method, and its application. The microorganisms include... Haemophilus genus, Fusobacterium genus, Aggregatibacter genus, Lachnoanaerobaculum genus and Oribacterium One or more of the above-mentioned microorganisms are identified, and the abundance of one or more of these microorganisms is significantly positively correlated with taste sensitivity. The application method is as follows: 1) Collect oral biological samples; 2) Extract DNA from saliva samples and perform sequencing analysis; 3) Detect the abundance of microbial assemblage; 4) Verify the correlation between key characteristic oral microorganisms and individual taste sensitivity. The advantage is that it is a non-invasive and non-surgical method to determine individual differences in taste sensitivity, aiming to achieve efficient, low-cost, and accurate identification of individual taste sensitivity.

The present application relates to a kind of essential oil composition with the efficacy of improving immunity, belong to daily chemical technology field.The essential oil composition with the efficacy of improving immunity of the present application includes the following mass parts of components:Rowensha leaf essential oil 10-20 parts, eucalyptus essential oil 15-30 parts, green flower of guettarda speciosa essential oil 10-20 parts, guaiac essential oil 5-10 parts, cedar essential oil 5-20 parts.The essential oil composition with the efficacy of improving immunity of the present application can significantly reduce the secretion of TNF-alpha, and have certain inhibitory effect on streptococcus pneumoniae, haemophilus influenzae, in addition, also have certain antitussive efficacy, thereby verifying its efficacy of improving immunity, relieving respiratory discomfort.The composition of the present application can be used for preparing massage oil, aromatherapy spray, inhalant, cream, patch and other care products, with good application prospect.

The present application relates to the field of ophthalmic drugs, and particularly relates to an ophthalmic composition, a preparation method and application thereof, the ophthalmic composition comprising a compound as shown in formula I, an osmotic pressure regulator, a pH regulator and water for injection; the pH value of the ophthalmic composition is 4.0-6.0; the concentration of the compound as shown in formula I is 0.1-3.0% w / v, and the concentration of the osmotic pressure regulator is 0.3-10.0% w / v; the antibacterial activity against Streptococcus pneumoniae, Staphylococcus aureus and Staphylococcus epidermidis is 2-8 times that of levofloxacin and moxifloxacin hydrochloride; the antibacterial activity against Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli and Pseudomonas aeruginosa is also strong, and is equivalent to that of levofloxacin and moxifloxacin hydrochloride; the irritation is small, the light stability and high-temperature stability are good, the quality and drug safety are guaranteed, and the application value is good.

The invention discloses a Chinese grass tortoise source Hafnia alvei strain and application thereof, and relates to the technical field of microorganism application. The virulence gene combination is derived from liver tissues of diseased Chinese grass turtles, the whole genome of the virulence gene combination comprises a phenol glycolipid system gene cluster, a multiple iron acquisition system and type VI secretion system gene cluster, an adhesin array and toxin system gene cluster and an alginate biofilm and multiple secretion system gene cluster, the Hafnia alvei strain is named as Hafnia alvei JX2025 strain, and is preserved in the China Center for Type Culture Collection (Wuhan) on November 17, 2025, and the preservation number is CCTCC M 20252572. The JX2025 strain can be used as a pathogen for preparing a hafnia alvei infected animal model, and the unique virulence gene spectrum of the JX2025 strain provides important molecular basis and data support for pathogenic mechanism research of related diseases, vaccine target screening and development of novel antibacterial drugs.