The present invention falls within the fields of
molecular biology, medical sciences and
immunology, and relates especially to preparations for medical purposes. In particular, the present invention relates to immunogenic compositions and / or formulations and / or polyvalent veterinary vaccines with a
broad spectrum of protection against serovars of Glaesserella parasuis (G. parasuis), based on inactivated antigens, to a
dosage form comprising said vaccine formulation, to the process for producing inactivated G. parasuis antigens, as well as to the process for producing said vaccine formulation. Additionally, the present invention relates to a combination of clinical strains, to the use of said combination of clinical strains in the manufacture of a
polyvalent vaccine formulation for the prevention of infections caused by clinical strains of G. parasuis, regardless of their capsular type, which cause Glässers
disease (GD), and to a kit comprising a combination of clinical strains and a
preservative solution.