3685results about How to "Effective isolation" patented technology

A membrane applied to the ostium of an atrial appendage for blocking blood from entering the atrial appendage which can form blood clots therein is disclosed. The membrane also prevents blood clots in the atrial appendage from escaping therefrom and entering the blood stream which can result in a blocked blood vessel, leading to strokes and heart attacks. The membranes are percutaneously installed in patients experiencing atrial fibrillations and other heart conditions where thrombosis may form in the atrial appendages. A variety of means for securing the membranes in place are disclosed. The membranes may be held in place over the ostium of the atrial appendage or fill the inside of the atrial appendage. The means for holding the membranes in place over the ostium of the atrial appendages include prongs, stents, anchors with tethers or springs, disks with tethers or springs, umbrellas, spiral springs filling the atrial appendages, and adhesives. After the membrane is in place a filler substance may be added inside the atrial appendage to reduce the volume, help seal the membrane against the ostium or clot the blood in the atrial appendage. The membranes may have anticoagulants to help prevent thrombosis. The membranes be porous such that endothelial cells cover the membrane presenting a living membrane wall to prevent thrombosis. The membranes may have means to center the membranes over the ostium. Sensors may be attached to the membrane to provide information about the patient.

Electro-winning of active metal (e.g., lithium) ions from a variety of sources including industrial waste, and recycled lithium and lithium-ion batteries is accomplished with an electrolyzer having a protected cathode that is stable against aggressive solvents, including water, aqueous electrolytes, acid, base, and a broad range of protic and aprotic solvents. The electrolyzer has a highly ionically conductive protective membrane adjacent to the alkali metal cathode that effectively isolates (de-couples) the alkali metal electrode from solvent, electrolyte processing and / or cathode environments, and at the same time allows ion transport in and out of these environments. Isolation of the cathode from other components of a battery cell or other electrochemical cell in this way allows the use of virtually any solvent, electrolyte and / or anode material in conjunction with the cathode. The electrolyzer can be configured and operated to claim or reclaim lithium or other active metals from such sources.

The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.

Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure comprising a plurality of fingers which are radially outwardly expandable with respect to a longitudinal axis to permanently engage the interior wall of the left atrial appendage, wherein the filtering membrane is attached to the support structure extending across the ostium of the left atrial appendage.

Alkali (or other active) metal battery and other electrochemical cells incorporating active metal anodes together with aqueous cathode / electrolyte systems. The battery cells have a highly ionically conductive protective membrane adjacent to the alkali metal anode that effectively isolates (de-couples) the alkali metal electrode from solvent, electrolyte processing and / or cathode environments, and at the same time allows ion transport in and out of these environments. Isolation of the anode from other components of a battery cell or other electrochemical cell in this way allows the use of virtually any solvent, electrolyte and / or cathode material in conjunction with the anode. Also, optimization of electrolytes or cathode-side solvent systems may be done without impacting anode stability or performance. In particular, Li / water, Li / air and Li / metal hydride cells, components, configurations and fabrication techniques are provided.

The invention relates to a laterally coupled bulk acoustic wave (LBAW) filter comprising a vibration layer for carrying bulk acoustic waves, electrode means comprising a first electrode coupled to the vibration layer for exciting to the vibration layer at least one longitudinal wave mode having a first frequency band and one shear wave mode having a second frequency band, and a second electrode coupled to the vibration layer for sensing the filter pass signal, the first and second electrodes being laterally arranged with respect to each other, and an acoustic reflector structure in acoustic connection with the vibration layer. According to the invention, the reflector structure is adapted to acoustically isolate the vibration layer from its surroundings at the first frequency band more efficiently than at the second frequency band for suppressing the effect of the shear wave mode at the second frequency band from the filter pass signal. The invention helps to improve the quality of LBAW filter passbands.

Alkali (or other active) metal battery and other electrochemical cells incorporating active metal anodes together with aqueous cathode / electrolyte systems. The battery cells have a highly ionically conductive protective membrane adjacent to the alkali metal anode that effectively isolates (de-couples) the alkali metal electrode from solvent, electrolyte processing and / or cathode environments, and at the same time allows ion transport in and out of these environments. Isolation of the anode from other components of a battery cell or other electrochemical cell in this way allows the use of virtually any solvent, electrolyte and / or cathode material in conjunction with the anode. Also, optimization of electrolytes or cathode-side solvent systems may be done without impacting anode stability or performance. In particular, Li / water, Li / air and Li / metal hydride cells, components, configurations and fabrication techniques are provided.

Gas-operated automatic and semi-automatic guns are improved by having a bisectional barrel with demountable and interchangeable muzzle sections wherein the breech section has a rifled bore and by having an actuation cylinder mounted to the receiver instead of the barrel. The muzzle sections are connected to the breech section via a tapered plug that locks into a tapered socket of the breech section. A port in the tapered plug joins with a port in the tapered socket to deliver gas from the barrel bore to the actuation cylinder and the tapered plug port in each interchangeable muzzle section is sized to provide automatic control of the proper amount of gas to cause the gun to function at its best rate based on the ammunition, silencer and length of the particular muzzle section selected by the user.

A selectively rotatable vehicle seat assembly includes a vehicle seat having lower and back portions. The lower portion has a bottom surface positionable medially of a pair floor runner supports. A chair mount is connected to the bottom surface and includes elongated guide posts and a central shaft. The assembly further includes a power mechanism for rotating the vehicle seat and a support plate slidably positionable between extended and retracted positions. The support plate includes rollers spaced along opposed edge portions thereof and grooves extending along a partial length thereof. Such posts and shaft include flange portions prohibiting vertical movement of the chair mount. A base member, secured adjacent to the floor runner supports, includes upper and lower portions. The upper portion further includes oppositely spaced channels for directing the rollers therealong.

A shaft seal assembly for maintaining a seal during shaft misalignment comprising a first sealing means adjacent said shaft with a defined clearance between said shaft and said sealing means, said shaft moveable axially in relation to said first sealing means; a second sealing means, said first sealing means partially encompassed within second sealing means and in cooperative communication with said second sealing means; a third sealing means, said second sealing means partially encompassed within third sealing means and in cooperative communication with said third sealing means, said third sealing means attached to said housing or vessel and allowing said first sealing means and second sealing means to cooperatively respond to said forces produced by angular misalignment of said shaft during rotation of said shaft while maintaining defined clearance between said shaft and said sealing means.