44 results about "Atrial Appendage" patented technology

An implant includes a plurality of foam layers attached together, wherein each foam layer includes a plurality of wedges monolithically formed with a base portion. A cap layer of foam may be attached at an axial end of the foam layers attached together. The cap layer of foam is disk-shaped and is devoid of wedges. A method of making an implant includes cutting disk-shaped pieces of foam partially through their thickness to define pluralities of wedges monolithically formed with base portions, securing the base portions in a contracted configuration to flare the pluralities of wedges apart from each other, and attaching the base portions such that adjacent pluralities of wedges are interdigitated.

An occlusive medical implant for implantation within a left atrial appendage may include an expandable framework configured to self-expand from a collapsed configuration to an expanded configuration, and an occlusive element disposed on a proximal portion of the expandable framework. At least a portion of the expandable framework may be mechanically expandable from the expanded configuration to a securement configuration. When the occlusive medical implant is disposed within the left atrial appendage, the expandable framework exerts a first radial force on the left atrial appendage in the expanded configuration and the expandable framework exerts a second radial force on the left atrial appendage in the securement configuration. The second radial force is greater than the first radial force.

This invention relates to an occlusion device and corresponding tooling, comprising a relatively independent fixing part and a sealing part, which are assembled to form the occlusion device. Thus, the fixing part and the sealing part can be manufactured, fabricated, and transported independently, and then assembled according to the required dimensions when implantation is needed. Therefore, the assembled left atrial appendage occlusion device has a wider range of size combinations, thus possessing good adaptability and fully adaptable to some special-sized left atrial appendage shapes. Simultaneously, the tooling facilitates the assembly of the occlusion device, enabling efficient and precise assembly with minimal impact on the device's physical properties and lifespan.

A left atrial appendage closure implant may include a support frame including a first bend extending from a proximal collar to a second bend, a first segment extending from the second bend to a third bend, a second segment extending from the third bend to a fourth bend, and a third segment extending from the fourth bend to a distal collar, wherein the support frame is actuatable from a first constrained position to a second flowering position to a third mid-deployment position to a fourth unconstrained position. An implant may include a self-expanding support frame having a circumference and a central longitudinal axis, a membrane disposed over at least a portion of the support frame, and a plurality of anchors arranged into a first row and a second row such that the first row and the second row form a staggered pattern about the circumference of the support frame.

Disclosed delivery catheters have a three-dimensional curvature that facilitates reaching the RAA from the inferior vena cava, positioning the distal end of the catheter generally parallel to the plane of the pericardial space at the puncture location within the RAA, orienting the puncturing device in a direction that avoids the right coronary artery, aorta, pulmonary artery, and other structures to prevent bystander injury to such structures, and provides sufficient rigidity to puncture through a wall of the RAA into the pericardial space.

This invention relates to a tissue closure clip, the clip body of which includes a first clamping arm, a second clamping arm, and a curved arm connecting the proximal ends of the two; the first clamping arm and the second clamping arm both extend longitudinally between the first and second clamping arms and contact each other, wherein the first clamping arm includes a first connecting portion disposed between its proximal and distal ends for connecting the distal end of the first clamping arm, and the second clamping arm includes a second connecting portion disposed between its proximal and distal ends for connecting the distal end of the second clamping arm. The tissue closure clip is carefully optimized in terms of size, has a wider range of applicability, and can be delivered to the ideal clamping position at the root of the left atrial appendage in more or even all patients, providing balanced and complete clamping and closure of the left atrial appendage, thereby improving the success rate of the surgery and reducing patient discomfort.

A medical system can include a left atrial appendage closure device including an expandable frame configured to transition between a collapsed delivery configuration and an expanded deployed configuration and a proximal hub disposed along a central longitudinal axis of the expandable frame; wherein the left atrial appendage closure device includes a sensor disposed at least partially within an interior of the expandable frame and axially movable relative to the proximal hub; wherein the proximal hub includes a first threaded connection structure; and a delivery catheter including a core wire extending axially within a lumen of the delivery catheter, the core wire having a second threaded connection structure at a distal end thereof, the second threaded connection structure configured to releasably engage with the first threaded connection structure in an unreleased configuration and the second threaded connection structure disengaged from the first threaded connection structure in a released configuration.

A medical device system may include an occlusive implant including a central hub and a plurality of elongate members configured to shift between extended and radially expanded configurations. The central hub includes a plurality of conduits extending from a proximal end to a radially outward facing surface. The plurality of elongate members is configured to extend through the conduits in the radially expanded configuration. An implant remodeling tool may include an elongate sheath having at least one lumen, a plunger guide, and a plurality of plunger shafts extending from the at least one lumen through the plunger guide. The plunger guide is configured to direct the plunger shafts radially outward as the plunger shafts are advanced distally. The plunger shafts are configured to engage a medical implant and urge at least a portion of the implant radially outward.

The present application relates to the technical field of medical devices, in particular to the technical field of implantable medical devices in the lumen, and more particularly to a medical device implanted in the lumen through an interventional procedure, and specifically to a fixing component for an implantable medical device and a preparation method thereof, and to an implantable medical device containing the fixing component, such as a closure device, in particular a left atrial appendage closure device. The fixing component comprises a central tube and a plurality of support rods arranged in a ring shape and extending outward from one end of the central tube, and the plurality of support rods are first gathered on one side outside the tube opening of the central tube to form a cross arrangement and then extend to the periphery to form the radial outer edge of the fixing component. The fixing component has stable structure, good safety and wide applicability, and can achieve good positioning effect in the body cavity.

One method involves using a processor to identify the septum and left atrial appendage (LAA) of a patient's heart in an anatomical diagram of at least a portion of the heart. An access surface is defined on the anatomical diagram through which a medical device engages with the LAA, the device to be delivered via a sheath penetrating the septum. The normal to the access surface is calculated. Multiple curves are calculated, each curve having (i) an end tangent to the normal, (ii) a second end contacting the septum, and (iii) conforming to specific mechanical properties of the sheath. Multiple candidate locations on the septum are derived from these curves for transseptal puncture using the sheath. These multiple candidate locations are presented to a user.

An implant for occluding a left atrial appendage includes an expandable framework including a central spine and a plurality of branch layers extending outward from the spine. Each branch layer includes at least one layer of foam fixedly attached thereto. Branches within each branch layer are circumferentially misaligned with branches within other branch layers. The plurality of branch layers includes first, second, and third branch layers fixedly attached to first, second, and third ring members coupled to the spine.

The method, device and application of left atrial partitioning can realize the geographic calibration of electrophysiological analysis, achieve 100% repeatability, and easily perform independent in-depth analysis of each subregion of the left atrium, realizing the regional and refined depiction of the atrial fibrillation matrix. The method includes: (1) importing high-density mapping point cloud data exported from mainstream electrophysiological systems, including electrical parameters such as X, Y, Z coordinates, voltage, and activation time; (2) identifying key feature structures in the point cloud data, including the boundaries of the left pulmonary vein ablation circle, the right pulmonary vein ablation circle, the mitral valve annulus region, and the left atrial appendage region, and using these as the basic anchor points for partitioning; (3) constructing three-dimensional spatial geometric rules to unambiguously assign each data point to one of the anatomical regions; (4) outputting a new point cloud dataset with clear regional labels and generating statistical reports for each partition, or visually displaying three-dimensional models of partitions with different color codes.

This utility model relates to a tissue closure clip, the clip body of which includes a first clamping arm, a second clamping arm, and a curved arm connecting the proximal ends of the two. The first clamping arm and the second clamping arm both extend longitudinally between the first and second clamping arms and are in contact with each other. The first clamping arm includes a first connecting portion located between its proximal and distal ends for connecting the distal end of the first clamping arm, and the second clamping arm includes a second connecting portion located between its proximal and distal ends for connecting the distal end of the second clamping arm. The tissue closure clip has been carefully optimized in terms of size, resulting in a wider range of applicability. It can be delivered to the ideal clamping position at the root of the left atrial appendage in more or even all patients, providing balanced and complete clamping and closure of the left atrial appendage, thereby improving the success rate of the surgery and reducing patient discomfort.

The application provides a sheath tube of an adjustable bending guide sheath, a sheath seat and a bonding method, and is mainly applied to an adjustable bending guide sheath in the field of atrial fibrillation ablation treatment or the field of atrial fibrillation left atrial appendage occlusion. In the application, the structure of a sheath seat fixing mechanism and a sheath tube clamping mechanism is systematically designed, and the bonding method of the sheath seat fixing mechanism and the sheath tube clamping mechanism is exemplarily described. The problems of low qualified rate and time-consuming in the bonding process can be solved, and the qualified rate and efficiency of the bonding of the adjustable bending sheath tube and the sheath seat are improved.

This invention relates to an occlusion device and tooling, comprising a relatively independent fixing part and a sealing part. The fixing part and the sealing part are assembled to form the occlusion device, which is then loaded into a sheath. The assembly and loading processes are performed simultaneously. Thus, the fixing part and the sealing part can be manufactured, fabricated, and transported independently, and then assembled according to the required dimensions when implantation is needed. Therefore, the assembled left atrial appendage occlusion device has a wider range of size combinations, resulting in better adaptability and fully adaptability to some special-sized left atrial appendage shapes. Simultaneously, the tooling facilitates the assembly of the occlusion device, enabling efficient and precise assembly with minimal impact on the device's physical properties and lifespan.

The present invention relates to a pulling device used for a degradable left atrial appendage occlude. The pulling device comprises: a main body, the main body being provided with a display unit used for displaying a pulling signal; a fixing assembly, the fixing assembly being slidably connected to the main body by means of a conversion assembly, and the conversion assembly being used for converting a movement signal of the fixing assembly into a display signal that can be displayed on the display unit; and a delivery steel cable, one end of the delivery steel cable being connected to the fixing assembly, and the other end of same being connected to a left atrial appendage occluder. The fixing assembly is slidably connected to the main body, so that an external pulling force applied to the degradable left atrial appendage occluder can be buffered, and the pulling force of the main body does not directly act on the delivery steel cable, thereby improving the operation experience of users; moreover, the pulling force of the fixing assembly is converted into a visual signal by means of the conversion assembly, so that operators can apply pulling forces more visually, thereby reducing the risks of the displacement and detachment of occluders caused by excessively high pulling forces.

Devices and methods for occluding the left atrial appendage (LAA) are described. [Solution] The device removes the LAA from the bloodstream, particularly in patients with atrial fibrillation, to prevent blood from forming a blood clot within the LAA and subsequently causing embolism. The implantable device is delivered into the LAA via transcatheter delivery and fixed within the LAA. The implant comprises an expandable compliant frame and an expandable, shape-conforming tubular foam body. The device may have an antithrombotic cover at its proximal end. The frame may have recapture struts that are inclined radially outward from a central hub. The frame may have axially extending sidewall struts, and adjacent pairs of sidewall struts may be joined at one or more vertices. Anchors extend from the frame, penetrate into the foam, and engage with the tissue.

A left atrial appendage closure device fitted to close the left atrial appendage includes a conical insert, which is formed from an inflatable foam and fitted for transseptal delivery to the LAA. A polymer cover is placed on the conical insert, which is fitted to protect the conical insert during transseptal delivery to the LAA and to be removed after transseptal delivery to the LAA. Before inflation of the conical insert, the insert lumen extends within the conical insert. A tubular support rod extends through the insert lumen and is operably connected to at least a portion of the polymer cover, and the tubular support rod itself defines a tubular support rod lumen fitted to accommodate a guidewire for advancing the insert into the LAA and / or a radiofrequency (RF) energy wire fitted for transseptal puncture.

This invention provides a cardiac tissue closure device. The cardiac tissue closure device includes a first clamping arm, a second clamping arm, and an elastic portion. The first clamping arm includes a first inner arm and a first outer arm disposed opposite to each other, connected by a first elastic member. The second clamping arm includes a second inner arm and a second outer arm disposed opposite to each other, connected by a second elastic member. One end of the first clamping arm is rotatably connected to one end of the second clamping arm. The elastic portion provides clamping force to the first and second clamping arms. The cardiac tissue closure device of this invention provides clamping force through the elastic portion. This clamping force is applied to the outer sides of the first and second clamping arms, thereby driving the clamping arms to flatten the inner atrial appendage, achieving closure of the atrial appendage. This prevents folding gaps caused by ligation of the atrial appendage and avoids the risk of residual blood flow.

A medical device for occluding a left atrial appendage ("LAA") may include a proximal occluding member to cover an ostium of the LAA and a distal occluding member to be received within a cavity of the LAA. A connecting member may connect the proximal occluding member to the distal occluding member. An occluding material may be uncoupled from the proximal occluding member in a delivery condition of the proximal occluding member, and uncoupled from the distal occluding member in a delivery condition of the distal occluding member, the occluding material configured to at least partially fill and occlude the LAA. In some examples, the distal occluding member is entirely excluded, and the medical device includes other anchoring provisions, such as tethers that latch onto a back wall of the LAA.

Described herein are examples of a left atrial appendage (“LAA”) occlusion or elimination implant device further configured to ablate tissue located at an atrium of the heart or nearby veins and ostia. The implant device can be delivered to a patient's heart using a catheter system and includes a contact member comprising one or more electrodes. In use, the electrodes of the contact member can perform unipolar or bipolar ablation at an ablation site that is distinct from an ostium or interior of the LAA. The implant device can then be re-positioned at least partially within the LAA, and the contact member can be implanted to occlude or eliminate the LAA. The implant device can further include a securing element comprising one or more electrodes, the securing element configured to cooperate with the contact member in performing unipolar or bipolar ablation and / or occluding or eliminating the LAA.

A system for occluding a left atrial appendage (“LAA”) includes a delivery device and an LAA occluder. The LAA occluder has an indicator electrode coupled to a connector electrode via a conducting wire. The delivery device has a connector with a connector electrode configured to be coupled to a navigation system via a conducting wire. During implantation, the delivery device is coupled to the LAA occluder so that the connector electrodes are electrically coupled, resulting in the indicator electrode being conductively coupled to the navigation system. After the LAA occluder is deployed into the LAA, the delivery device is disconnected from the LAA occluder to allow the LAA occluder to remain in the patient.

A system for occluding a left atrial appendage ("LAA") includes a delivery device and an LAA occluder. The LAA occluder has an indicator electrode coupled to a connector electrode via a conducting wire. The delivery device has a connector with a connector electrode configured to be coupled to a navigation system via a conducting wire. During implantation, the delivery device is coupled to the LAA occluder so that the connector electrodes are electrically coupled, resulting in the indicator electrode being conductively coupled to the navigation system. After the LAA occluder is deployed into the LAA, the delivery device is disconnected from the LAA occluder to allow the LAA occluder to remain in the patient.

This invention relates to a sealing device, comprising a fixing part, a sealing part, and a connecting part connecting the sealing part and the fixing part. The fixing part includes a support body that extends radially outward from a converging position and is flipped by a flipping part to form the supporting part. The connecting part includes a buffer part located between the fixing part and the sealing part, and the buffer part includes a retractable telescopic structure. In the sealing device of this invention, a buffer part is added. When the fixing part moves with the inner wall of the left atrial appendage, the buffer part can partially offset or eliminate the deformation of the fixing part. Therefore, the deformation and stress of the fixing part are minimized or completely eliminated when transmitted to the sealing part, thereby ensuring a stable seal of the sealing device and maintaining a constant position of the sealing part relative to the opening of the left atrial appendage.

Medical devices, systems and methods for forming an occlusive material for occluding a left atrial appendage of a heart are provided. In one embodiment, the occlusive material includes a foam portion that extends as a single piece, seamless monolithic structure that is sized to couple to an external side of a framework of a medical device. In another embodiment, the occlusive material may include a polymeric laminate. Such polymeric laminate may be adhered to an outer side of the foam portion. Further, various embodiments for forming a polymer laminate are provided.

A method for left atrial appendage (LAA) invagination, including:convexing a portion of the LAA wall into the LAA, wherein the convexing includes convexing the LAA wall portion by applying suction from a collapsible suction cup contacting the LAA wall on the LAA wall portion;grasping the convexed LAA wall portion within the LAA, following the convexing; invaginating the LAA at least partly into the left atria (LA) using the convexed LAA portion;wherein the grasping includes controllably collapsing the collapsible suction cup on the convexed LAA portion with a force sufficient to hold the convexed LAA portion during the invaginating.

An implant includes a plurality of foam layers attached together, wherein each foam layer includes a plurality of wedges monolithically formed with a base portion. A cap layer of foam may be attached at an axial end of the foam layers attached together. The cap layer of foam is disk-shaped and is devoid of wedges. A method of making an implant includes cutting disk-shaped pieces of foam partially through their thickness to define pluralities of wedges monolithically formed with base portions, securing the base portions in a contracted configuration to flare the pluralities of wedges apart from each other, and attaching the base portions such that adjacent pluralities of wedges are interdigitated.

Disclosed herein are systems and methods for applying an occlusion clip. The medical device can comprise a handle, an elongated shaft extending from the handle, the elongated shaft comprising a proximal end, a distal end, and a central lumen. The medical device can further comprise an end effector at the distal end of the elongated shaft, the end effector comprising a first jaw and a second jaw configured to engage with and deliver the occlusion clip to a target tissue, wherein the end effector comprises a link mechanism configured to move the first jaw and the second jaw relative to each other. The medical device can further comprise a plurality of cables extending through the central lumen. The medical device can further comprise an articulation plate coupled to the handle. The medical device can further comprise an articulation joint coupling the articulation plate and the elongated shaft.