64 results about "Interatrial septum" patented technology

An asymmetric device for regulating blood volume distribution across a patient's atrial septum having a first expandable end region and a second expandable end region. The first expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the first expandable end region extends into the patient's left atrium and an inlet end of the first expandable end region is in a first plane. The second expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the second expandable end region extends into the patient's right atrium and an outlet end of the second expandable end region is in a second plane, such that the first plane intersects the second plane. The device further includes a neck region joining the first expandable end region to the second expandable end region, wherein the neck region is sized and shaped for placement in the patient's atrial septum.

Interatrial shunts having incorporated physiologic sensors are provided for monitoring and treating cardiovascular syndromes, including heart failure and pulmonary hypertension, in which the one or more sensors are affixed to the shunt to measure a physiologic parameter within the interatrial shunt. The one or more sensors may be directly affixed to or within a lumenal surface of the shunt or may be disposed on a support structure in a spaced relation to the shunt lumen, the one or more sensors disposed at locations subject to little or no pannus formation or cardiac wall motion artifact.

Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.

An asymmetric device for regulating blood volume distribution across a patient's atrial septum having a first expandable end region and a second expandable end region. The first expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the first expandable end region extends into the patient's left atrium and an inlet end of the first expandable end region is in a first plane. The second expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the second expandable end region extends into the patient's right atrium and an outlet end of the second expandable end region is in a second plane, such that the first plane intersects the second plane. The device further includes a neck region joining the first expandable end region to the second expandable end region, wherein the neck region is sized and shaped for placement in the patient's atrial septum.

Interatrial shunts having incorporated physiologic sensors are provided for monitoring and treating cardiovascular syndromes, including heart failure and pulmonary hypertension, in which the one or more sensors are affixed to the shunt to measure a physiologic parameter within the interatrial shunt. The one or more sensors may be directly affixed to or within a lumenal surface of the shunt or may be disposed on a support structure in a spaced relation to the shunt lumen, the one or more sensors disposed at locations subject to little or no pannus formation or cardiac wall motion artifact.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

A method and system for performing transseptal extracorporeal membrane oxygenation is disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. A first portion of the catheter system can remove blood from the patient, in some examples near the inferior vena cava. A second portion can return oxygenated blood to the patient, through the transseptal puncture and into the aorta.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

This invention discloses a method for preparing a simulated heart model and the simulated heart model itself. The method for preparing the simulated heart model includes: dividing a digital heart model into two parts along its coronal plane; preparing corresponding molding molds according to the structural characteristics of the two parts, each molding mold including an outer molding mold and an inner cavity molding mold; applying silicone to the molding surfaces of the outer molding mold and the inner cavity molding mold to form the endocardium and epicardium; applying silicone to the portion of the inner cavity molding mold used for molding the valve to form the valve; assembling the outer molding mold and the inner cavity molding mold to form a cavity; sequentially injecting silicone of corresponding hardness into the regions of the cavity used for molding the atrial myocardium, interatrial septal myocardium, ventricular myocardium, and interventricular septal myocardium to form heart model halves; and bonding the heart model halves corresponding to the two molding molds together to obtain the simulated heart model.

The present disclosure relates to medical devices. More particularly, this disclosure describes a vascular device allowing large bore transseptal access with subsequent atrial re-access by preplacing closures / tissue approximating sutures prior to creating a septostomy. Generally, the device may include a delivery catheter for puncturing and cutting the interatrial septum. An anchor of the delivery catheter may secure the suture in an atrium to a septum wall, for example, the left atrium. Incisions may be made by an expandable cutting implement which may use mechanical or radio frequency (RF) energy without interfering with the suture. A therapeutic instrument may be advanced through the tissue plane after the incisions are made by the cutting implement. Closure of the incision may be performed with the previously placed sutures.

The invention relates to an atrial septum puncture system which comprises a puncture needle body, an expansion tube and a handle part. The puncture needle body is movably arranged in the expansion tube, an exhaust gap is formed between the outer side of the needle wall of the puncture needle body and the inner side of the tube wall of the expansion tube, a first sealing structure is arranged between the puncture needle body and the expansion tube, and a through hole enabling the exhaust gap to be communicated with the needle cavity is formed in the needle wall. According to the interatrial septum puncture system, frequent exchange of a guide wire and a needle is not needed in the interatrial septum puncture operation process, operation steps are reduced, meanwhile, air can be exhausted, air can be prevented from entering the system in the use process, the probability that air enters the body of a patient can be reduced, and the operation efficiency is improved. And the risk of thrombus and thrombus formation of patients is reduced.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

This invention relates to a biodegradable cardiac occluder for bilateral rivetless atrial septal defects. The occluder includes a main body, a flow-blocking component, sutures, and a rivetless flat-face connector. The main body is a mesh structure comprising a first disc-shaped portion, a second disc-shaped portion, and a tubular portion. The flow-blocking component is a biodegradable membrane with at least two layers for blocking blood flow. The sutures are biodegradable sutures used to sew the flow-blocking component onto the main body and also serve as a closing suture. The rivetless flat-face connector includes a threaded hole and a delivery disc. This invention uses a small disc instead of rivets, achieving both re-delivery and the goal of reducing thrombosis incidence through rivetless design. The rivetless flat-face connector is biodegradable. During processing, it is woven into the mesh, making it convenient, safe, and quick.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

The present technology is generally directed to implantable medical devices and associated methods. For example, a system configured in accordance with embodiments of the present technology can include a body implantable into a patient and configured to undergo a shape change, the body having a conductive path with variable conductivity in portions thereof for selective and / or preferential heating. The body can be coupled with an energy source that can delivery energy to the body and / or conductive path, to promote the shape change in the body.

A method, system, and devices with an integrated retractable blade system for the intraarterial shunt are disclosed. According to one aspect, the cutting tool may comprise an elongate body where the elongate body has a proximal portion and a distal portion opposite the proximal portion. An inner shaft may extend within the distal portion of the elongate body and the inner shaft may have a proximal end and a distal end and a hub may be coupled to the distal end of the inner shaft. The cutting tool may have a cutting element with the hub coupled with the cutting element and movement of the hub transitions the cutting element between a collapsed position and an expanded position.

Anatomical wall crossing systems, devices, and related methods are disclosed in this patent document. An interatrial septum system may include, for example, a guidewire, a dilator, and a deflectable sheath, which is configured to safely deliver a puncture needle through an interatrial septum associated with the fossa ovalis and into a central region of the left atrium of the heart. The dilator may include a dilator nose having a first outer diameter and a dilator bevel section extending proximally from the dilator nose, which tapers from a second larger outer diameter to the first outer diameter. The lengths and interactions of the puncture needle and the dilator nose may be configured such that the puncture needle is inhibited from bending during use and striking the left side of the interatrial septum of the heart. The body of the guidewire may include at least one loop segment to provide stable support in the left atrium for delivering a diagnostic or therapeutic device along its more proximal portion. The deflectable sheath may position and align the dilator nose relative to the fossa ovalis.

The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and / or a geometry of a lumen orifice to control the flow of blood through the lumen.

The application provides a method for fixing an interventional valve on a mitral valve, which comprises the following steps: driving a plurality of fixing nails into the left atrial side wall above the mitral valve; and connecting a fixing disc on the atrial septum through a connecting line to form a plurality of fixing lines above the mitral valve. The fixing method can form a plurality of fixing lines above the mitral valve, and the fixing lines can provide stable fixing support for the interventional valve implanted below, thereby effectively solving the problem that the current interventional mitral valve is difficult to be stably anchored, and the method for fixing the interventional valve on the mitral valve is simple and convenient to operate.

The present disclosure relates to medical devices. More particularly, this disclosure describes a vascular device allowing large bore transseptal access with subsequent atrial re-access by preplacing closures / tissue approximating sutures prior to creating a septostomy. Generally, the device may include a delivery catheter for puncturing and cutting the interatrial septum. An anchor of the delivery catheter may secure the suture in an atrium to a septum wall, for example, the left atrium. Incisions may be made by an expandable cutting implement which may use mechanical or radio frequency (RF) energy without interfering with the suture. A therapeutic instrument may be advanced through the tissue plane after the incisions are made by the cutting implement. Closure of the incision may be performed with the previously placed sutures.

A septostomy device 10 with a cutting structure or means 140 and tissue capture mechanisms 240, 250 is disclosed, along with a medical procedure for using the device. The system 10 is configured in such a way as to create a permanent interatrial aperture in the heart, including creating a permanent interatrial hole and / or removing tissue.

The utility model relates to the technical field of medical teaching tools, in particular to a pulmonary vein stenosis interventional operation training model, which comprises a bottom plate and a heart module mounted on the bottom plate, a left atrium and a right atrium are arranged in the heart module, and an inferior vena cava communicated with the right atrium is arranged on the heart module. The heart module is further provided with pulmonary veins communicated with the left atrium, through holes are formed in the left atrium and the right atrium at the interatrial septum position, sheet-shaped silica gel membranes are detachably installed at the positions of the through holes, and the heart module is provided with an operation opening in the upper side of the left atrium. The problems that when an existing training model carries out pulmonary vein stenosis interventional operation training, due to the fact that a stoma is a set through hole, when an operator is trained, the stoma puncturing step is omitted, and a good training effect on how to carry out interatrial septum puncturing is not achieved are solved.

The present invention discloses a tricuspid valve prosthesis, comprising: a stent body implanted at the tricuspid valve annulus for supporting artificial valve leaflets; an anchoring structure disposed above the stent body for anchoring the stent body at the native annulus to prevent its displacement; wherein the anchoring structure is configured to be partially attached to the fossa ovalis of the interatrial septum, and a retention force is formed by attaching to the fossa ovalis, thereby realizing the anchoring effect on the valve prosthesis. Inspired by the native structure of the fossa ovalis, the present invention makes full use of the concave structure of the fossa ovalis to partially clamp the anchoring structure in the fossa ovalis, thereby providing a certain retention force to prevent the valve prosthesis from shifting during cardiac compression; the anchoring structure of the present invention changes the traditional anchoring method of clamping or grasping valve leaflets, and will not pull the chordae tendineae or damage the valve leaflets.

The invention relates to a left heart drainage catheter, and provides a left heart drainage catheter and a drainage catheter system. The left heart drainage catheter comprises an operating handle; the drainage tube is connected to the far end of the operating handle; the drainage tube comprises a tube body and an ablation electrode, and the ablation electrode is fixed to the far end of the tube body and used for conducting ablation on atrial septum perforation. The drainage tube further comprises an electrode wire connected to the ablation electrode. The operation handle comprises an electric connecting part, the near end of the electrode wire is connected to the electric connecting part, and the electric connecting part is used for being connected with an ablation host so as to provide ablation energy for the ablation electrode. The technical problems that left atrium drainage and atrial septal stoma operation steps are many, and operation is complex are mainly solved.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a RF energy-based transcatheter interatrial septum excision device configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a tissue stabilizer catheter, a tissue cutter attached to a tissue cutter catheter, a remotely located RF generator connected to an RF cathode and anode of the device assembly.

A system for regulating blood flow within a heart includes a stent sized for placement in a blood vessel of the heart. A lumen of the stent is adjustable for cyclically obstructing the flow of the blood through the stent and thereby improving the efficiency of the heart. In one example, an elongate member extends into a chamber of the heart and pressure changes within the heart chamber are communicated to the stent for altering a diameter of the lumen. The elongate member may be a tube for allowing a fluid to move between the stent and the heart chamber. The elongate member may be anchored within the heart, such as along an atrial septum.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal Disclosed herein is a RF energy-based transcatheter interatrial septum excision device configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a tissue stabilizer catheter, a tissue cutter attached to a tissue cutter catheter, a remotely located RF generator connected to an RF cathode and anode of the device assembly.

Closure devices that selectively control blood flow between the right atrium and the left atrium of a heart of a patient. The control of blood flow can be based on detected values from a pressure sensor. The closure devices can include a body configured to engage native tissue when the device is deployed across the septal wall. In a first state at least a portion of (an inner surface of) a lumen is closed, preventing blood flow through the closure device. In a second state, the lumen is open to enable blood flow from the left atrium to the right atrium. A closure element can be selectively adjusted to control the flow of blood through the lumen. A volume of an expandable chamber can be increased or decreased to place the closure device into the first state or the second state.

The present application provides a heart valve positioning system, which includes: a pre-guiding device, which can be delivered to the heart valve via the delivery system and capture the native leaflets; a positioning device, which includes: a tubular first positioning structure and a locking structure, the first positioning structure is provided with a first end, a second end and a penetration portion, the first end and the second end are separated from each other in the delivery state, and the penetration portion is used for the pre-guiding device to penetrate the inner cavity of the first positioning structure, so that the first end and the second end are connected to each other through the locking structure under the guidance of the pre-guiding device, and the first positioning structure forms a closed ring, so as to gather at least a part of the native leaflets inside the closed ring. The heart valve positioning device of the present application and the artificial valve are delivered through the atrial septum from the same pathway, which is simple to operate and can avoid causing damage to the aortic valve.