75 results about "Interatrial septum" patented technology

A percutaneous heart valve prosthesis (1) has a valve body (2) with a passage (9) extending between the first and second ends (7, 8) of the valve body (2). The valve body (2) is collapsible about a longitudinal axis (10) of the passage (9) for delivery of the valve body (2) via a catheter (18). One or more flexible valve leaflets (3, 4) are secured to the valve body (2) and extend across the passage (9) for blocking bloodflow in one direction through the passage (9). An anchor device (5), which is also collapsible for delivery via catheter (18), is secured to the valve body (2) by way of an anchor line (6). A failed or failing mitral heart valve (101) is treated by percutaneously locating the valve body (2) in the mitral valve orifice (102) with the anchor device (5) located in the right atrium (107) and engaging the inter-atrial septum (103), such that the taught anchor line (6) acts to secure the valve body (2) within the mitral valve orifice (102).

Visualization apparatus and methods for transseptal access are described herein where intravascular access across a septal wall is facilitated via devices which provide for direct visual viewing of tissue area. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to the tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid can be pumped into the imaging hood until the fluid displaces any blood leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Any number of therapeutic tools or a guidewire can be passed through the catheter and into the imaging hood for crossing the septal wall and passing the guidewire or instruments therethrough.

A percutaneous heart valve prosthesis (1) has a valve body (2) with a passage (9) extending between the first and second ends (7, 8) of the valve body (2). The valve body (2) is collapsible about a longitudinal axis (10) of the passage (9) for delivery of the valve body (2) via a catheter (18). One or more flexible valve leaflets (3, 4) are secured to the valve body (2) and extend across the passage (9) for blocking bloodflow in one direction through the passage (9). An anchor device (5), which is also collapsible for delivery via catheter (18), is secured to the valve body (2) by way of an anchor line (6). A failed or failing mitral heart valve (101) is treated by percutaneously locating the valve body (2) in the mitral valve orifice (102) with the anchor device (5) located in the right atrium (107) and engaging the inter-atrial septum (103), such that the taught anchor line (6) acts to secure the valve body (2) within the mitral valve orifice (102).

The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.

A method of locating the fossa ovalis in a patient by locating the His bundle, plane of the interatrial septum, and coronary sinus ostium in a patient, and thereafter locating the fossa ovalis on the basis of one or more predetermined distances between the fossa ovalis and the His bundle and the coronary sinus ostium. An apparatus for locating the fossa ovalis and performing a transseptal puncture is also provided.

A method for detecting and closing the patent foramen ovale including the steps of locating a His bundle, plane of the interatrial septum, and coronary sinus ostium in a patient; identifying a fossa ovalis on the basis of one or more predetermined distances between the fossa ovalis and the His bundle, the plane of the interatrial septum, and the coronary sinus ostium; locating a patent foramen ovale by probing the junction between the fossa ovalis and a limbus of the fossa ovalis; and causing injury to the surfaces of at least one of a septum primum and a septum secundum within the patent foramen ovale. Another method includes the steps of locating a tunnel of a patent foramen ovale by probing the junction between a fossa ovalis and a limbus of the fossa ovalis and causing injury to the surfaces of at least one of a septum primum and a septum secundum within the tunnel of the patent foramen ovale by applying energy to at least one of the septum primum and the septum secundum. Apparatuses to perform these methods are also provided.

The present invention provides for therapeutic treatment methods, devices, and systems for the partial or complete closure or occlusion of a patent foramen ovale (“PFO”). In particular, various methods, devices, and systems for joining or welding tissues, in order to therapeutically close a PFO are described. In yet another aspect of the invention, various methods, devices, and systems for the penetration of the interatrial septum enabling left atrial access are also provided.

An ablation therapy system and systematic method is provided for treating continuous atrial fibrillation. The therapy system includes a Multi-Channel RF Ablation Generator, an ECG interface, an assembly of at least three ablation catheters, and an ECG interface operably coupling and interfacing the catheters to both an ECG unit and the RF Ablation Generator. The systematic method includes transseptally accessing the Left Atrium (LA) through the septum of the patient's heart, and performing an endocardial pulmonary vein ablation procedure on the pulmonary vein ostial tissue surrounding one or more pulmonary veins in a manner treating aberrant conductive pathways therethrough. After performing the pulmonary vein ablation, the method further includes performing an endocardial atrial septum ablation procedure on the septal tissue in a manner treating aberrant conductive pathways therethrough.

Positioning of the distal end of a catheter at a desired location, for example, in the desired atrium of a patient's heart, can be determined or verified through measurement of blood gas values proximate to the distal end. In one embodiment, an oximeter is used to monitor oxygen saturation, for example, to distinguish between de-oxygenated venous blood and well-oxygenated arterial blood. Optical signals may be transmitted to the distal end of the catheter and received therefrom via optical fibers. Specifically, a catheter (300) has a number of optical fiber ends (308, 310 and 312) disposed at a distal end (304) thereof. A first fiber end (310) transmits the red and infrared optical signals. Fiber ends (308 and 312) are used for detecting reflected optical signals. The optical signals are then processed by a detector and an oximeter instrument to provide oxygen saturation readings that can indicate the position of the distal end of the catheter within the patient's heart or successful penetration of the interatrial septum.

Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.

The invention provides a plugging device, which comprises a metal skeleton and a flow resistance film, wherein the metal skeleton comprises a near-end disk surface, a far-end disk surface and a waistpart used for connecting the near-end disk surface with the far-end disk surface; the near-end disk surface and the far-end disk surface are both of a reticular structure weaved by metal wires; the near-end disk surface and the far-end disk surface are independently provided with a puncture hole, and the size of the puncture hole is far greater than the mesh openings of the near-end disk surface and the far-end disk surface; and the flow resistance film is arranged in the near-end disk surface and the far-end disk surface and covers the puncture holes, wherein the material of the flow resistance film is a macromolecule absorbable material. Since the near-end disk surface and the far-end disk surface of the above plugging device are independently provided with the puncture hole, if atrial septum puncture needs to be carried out in the future, a puncture needle can penetrate through the position of a puncture hole, and the interference of the metal skeleton of the plugging device can beeffectively avoided so as to be favorable for successfully carrying out atrial septum puncture surgery in the future.

The instant invention relates to transseptal access systems and methods for accessing the left atrium (52) from the right atrium (48) by crossing the interatrial septum (50). In particular, the instant invention is directed toward medical devices used with catheter assemblies in cardiology procedures that require transseptal puncture(s). The puncture assemblies (e.g., 10) have a moveable puncture device (e.g., 14) within a dilator (e.g., 16). The puncture device is biased in a retracted position. The position of the puncture assembly is precisely locatable. The puncture assembly is preferably flexible along the majority of the length of its and, therefore, can be used with any catheter assembly of any predetermined shape. The puncture device is adjustable from a position within the dilator to a position extending beyond the end of the dilator when necessary for use in transseptal procedures.

What is proposed is a method for the catheterization of the coronary arteries in which a catheter is introduced via the venous system into the right atrium, then passed through the interatrial septum and introduced into the left atrium, followed by the left ventricle, and into the ascending aorta to the opening of the coronary arteries, and also a catheter for the implementation of this method.

An asymmetric device for regulating blood volume distribution across a patient's atrial septum having a first expandable end region and a second expandable end region. The first expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the first expandable end region extends into the patient's left atrium and an inlet end of the first expandable end region is in a first plane. The second expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the second expandable end region extends into the patient's right atrium and an outlet end of the second expandable end region is in a second plane, such that the first plane intersects the second plane. The device further includes a neck region joining the first expandable end region to the second expandable end region, wherein the neck region is sized and shaped for placement in the patient's atrial septum.

The invention provides an interatrial septum puncturing assembly and an interatrial septum puncturing method. The interatrial septum puncturing assembly comprises a catheter sheath and an expansion tube, the expansion tube is arranged in the catheter sheath in an attaching and penetrating mode, and one end of the expansion tube is fixedly provided with multiple electrodes. According to the interatrial septum puncturing assembly and the interatrial septum puncturing method, due to the fact that one end of the expansion tube is fixedly provided with the electrodes, ablation puncturing can be performed, a tent shape cannot be formed in an ejecting mode when the expansion tube passes through the fossa ovalis myocardium, and safe and rapid puncturing is achieved; meanwhile, use of a puncture needle is omitted, therefore, the surgical operation steps are simplified, and not only is the operation time saved, but also the cost of the puncture needle is saved; in addition, the electrodes can be attached to the inner wall of a heart chamber to extract electrical signals in the heart chamber, the position of the fossa ovalis is accurately determined through the electrical signals, and the puncturing safety is improved.

The apparatus for closure of atrial septal defects includes a sheath having a proximal portion and a distal portion, the sheath defining a lumen extending therethrough, a handle positioned in communicating relation with the proximal portion of the sheath, and a balloon positioned in communicating relation the distal portion of the sheath. The distal portion of the sheath can include a soft tip having at least one hole defined therein. The handle can have a bidirectional control configured for controlling or deflecting the direction of the distal portion of the sheath by at least 90 degrees to aid in positioning and aligning the balloon, as well as an occlusion device into the ASD. The balloon, such as a sizing balloon, can measure the size of the ASD within the interatrial septum of a heart of a patient.

A method of identifying the fossa ovalis in a patient by positioning one or more electrodes against the tissue of the interatrial septum of the patient and acquiring unipolar and / or bipolar electrograms of the tissue of the interatrial septum while moving the electrodes to a plurality of positions against the tissue of the interatrial septum. The fossa ovalis is identified on the basis of unipolar voltage reduction, signal fractionation, broadened signal, reduced signal slew rate, reduced local myocardial impedance, increased phase angle and / or increased pacing threshold. An apparatus for identify the fossa ovalis is also provided.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

The invention provides a medical device and a fixing mechanism of medical equipment. The medical equipment can be conveniently located at a target position in the body through the fixing mechanism toachieve corresponding implantation or interventional treatment of the medical equipment, and accordingly, the medical effect is improved. The medical equipment can be a lead-free pacemaker, and physiological pace-making on the heart by the pacemaker is conveniently realized. The fixing mechanism comprises a base and fixing member, the extension direction of the base is parallel to that of a presetobject, and the fixing member is arranged on the outer wall of the base and extends around the base; one end of the fixing member is connected with the outer wall of the base, and a gap is formed between the other end of the fixing member and the outer wall of the base. During actual use, the base is stressed to rotate along the extension direction of the fixing member, and drives the fixing member to rotate together; during rotation, the fixing member is directly inserted into a tissue or a blood vessel wall parallel to the base, so that the medical equipment can be fixed into the atrium, the ventricle, the precava or other blood vessels, or fixed onto the interventricular septum or the interatrial septum.

The invention discloses a guiding sheathing canal, a catheter and an oval nest detection method for inter-atrial septal puncture. The guiding sheathing canal comprises a tail end sheathing canal and an adjustable bent section connected with the tail end sheathing canal, a first sheathing canal magnetic positioning sensor and a second sheathing canal magnetic positioning sensor are arranged at thetwo ends of the adjustable bent section respectively, the first sheathing canal magnetic positioning sensor is close to the tail end sheathing canal, and the distance between the end, close to the tail end sheathing canal, of the first sheathing canal magnetic positioning sensor and the free end of the tail end sheathing canal is remarked as L; the guiding sheathing canal is used for being matchedwith the catheter, the catheter can move in the axial direction of the guiding sheathing canal, the distance between the end, close to the tail end sheathing canal, of the first sheathing canal magnetic positioning sensor and the free end of the catheter is marked as D, and the free end of the catheter is provided with a pressure sensor and a catheter magnetic positioning sensor. According to theguiding sheathing canal, inter-atrial septal puncture is more accurate and effective, puncture time is saved, more importantly, zero ray in the puncture process can be achieved, the bodies of doctorsand patients are better protected against radiation influences, and the guiding sheathing canal is simple in structure, convenient to use and good in effect.

The invention provides a plugging device, and relates to the field of medical equipment, and the plugging device comprises: a plugging device body which is provided with a through hole, wherein the through hole extends along the axial direction of the plugging device body; and a flow blocking film which is arranged in the through hole so as to separate and block the through hole. Compared with the prior art, the plugging device keeps the structure and the working principle of a traditional plugging device, safety and effectiveness of the plugging device are guaranteed, the totally-closed sheet-shaped flow blocking film is arranged in the central through hole, blood flow is blocked from passing through the plugging device, meanwhile, the flow blocking film is easy to puncture and expand by means of the thin and brittle characteristics of the flow blocking film, therefore, the sheathing canal can be easily punctured and fed from the central through hole of the plugging device, and a channel is reserved for follow-up atrial septum puncture interventional operation.

The invention relates to a puncture needle component which comprises a puncture needle, a navigation guide wire, a sheathing tube with a dilator and a three-dimensional positioning and orienting device. The navigation guide wire is arranged inside the puncture needle to form an integrated guide-wire-shaped solid core puncture needle which is connected with the sheathing tube and the three-dimensional positioning and orienting device. The puncture needle component can be used for completing interventricular septum puncture and interatrial septum puncture through a venipuncture approach, the problems of the prior art can be solved effectively, unlimited selecting of surrounding blood vessel approaches of a pre-operation position can be realized, spatial position selecting of a puncture target can be limited effectively while moving direction of a needle tip of the puncture needle can be positioned accurately and objectively, and two steps of puncture spacing of the puncture needle and building of a guide wire rail can be completed in one step; the puncture needle component is safe, simple and convenient to operate, operating technical difficulty is lowered substantially, operating technical error risk is avoided completely, and risks such as perforation of free ventricular wall and cardiac tamponade are avoided fully.

The invention discloses a method for constructing a congenital heart disease with diminutive pulmonary blood animal model, which is characterized in that: a surgical knife enters a fourth intercostal of right chest lateral incision, and a pericardium is opened and suspended; an interatrial septum is directly expanded by a puncture needle and a balloon dilator from the right chest lateral under ultrasound guidance to form an atrial septal defect with the diameter of 1.0cm; a main pulmonary artery is sleeved by an artificial blood vessel sheet to monitor peripheral arterial blood pressure and differential pressure of a girdle place, and then the differential pressure is decreased gradually; and when the differential pressure of the girdle place of mild-moderate pulmonary stenosis is 20 to 30mmHg, or the differential pressure of the girdle place of severe pulmonary stenosis is more than or equal to 30mmHg, and the arterial blood pressure is kept stable, a girdle belt is fixed so as to form the congenital heart disease with diminutive pulmonary blood animal model. The method has the advantages of exactness, feasibility, simple and reliable operation method, convenient operation and a few complications; and the constructed animal model is more ideal and better adapts to changes of clinical pathophysiology of the disease.

A transseptal insertion device suitable for facilitating precise and safe transseptal puncture of a cardiac interatrial septum (100) includes a sheath (12) that defines a lumen and has a distal end that is closest to the cardiac interatrial septum of a patient and a proximal end that is external to the patent, a balloon (14) that is connected to the distal end of the sheath (12) in which the balloon (14), when inflated, overhangs and extends past the distal end of the sheath, preventing accidental puncturing of the cardiac interatrial septum (100) and stabilizing the transseptal insertion device against fossa ovalis of the cardiac interatrial septum (100), and a dilator (16) that is positioned within the at least one lumen. The dilator (16) has a distal end and is designed to and is capable of precisely puncturing the cardiac interatrial septum without the use of a needle or other sharp instrument. The balloon (14) includes one or more ultrasound transceivers (26).

The invention discloses a patent foramen ovale plugging device. The patent foramen ovale plugging device is characterized by comprising a woven mesh, a plugging device fixing rivet and a central connecting part. The patent foramen ovale plugging device is made of degradable materials so that the plugging device can be degraded and absorbed in vivo 2-3 years after the surgery, and therefore surgical treatment which is needed after a possible heart disease occurs is not affected; and resilience performance of the plugging device and fixation of the plugging device relative to the interatrial septum are greatly improved through the fixing rivet structure and the central connecting part. By means of the patent foramen ovale plugging device, the requirement on the mechanical property of the materials is reduced to the maximum extent, and therefore most absorbable materials can be applied in the field of plugging devices. The patent foramen ovale plugging device further comprises diaphragm baffles which are beneficial for endothelialization of the plugging device in the initial implantation period.

The invention relates to an interatrial septum puncture tool, which comprises an epitheca, an expander and a puncture needle, wherein the expander is pasted and arranged in the epitheca in a penetrating way, and the puncture needle is arranged in the expander in a penetrating way. The interatrial septum puncture tool is characterized in that the puncture needle comprises a head part, a neck part and a body part in sequential connection, the head part is a puncture needle head, the neck part is a tight spiral fine steel wire with at least one micro fine steel wire penetrating at the inner side, and the body part is a long soft steel wire. The tool has the advantages that the design is reasonable, and in addition, the condition of left atrium inner wall puncture injury by the needle head caused by puncture positioning inaccuracy or excessive puncture acting force can be avoided.