73 results about "Interatrial septum" patented technology

To provide a device assembly and a method for treating heart failure by normalizing an elevated blood pressure in the left atrium of the heart of a mammal.SOLUTION: Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between right and left atria of a heart for relief of an elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the components to and from the right atrium, a tissue retention mechanism, and an optional coaxial alignment mechanism.SELECTED DRAWING: Figure 1

An asymmetric device for regulating blood volume distribution across a patient's atrial septum having a first expandable end region and a second expandable end region. The first expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the first expandable end region extends into the patient's left atrium and an inlet end of the first expandable end region is in a first plane. The second expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the second expandable end region extends into the patient's right atrium and an outlet end of the second expandable end region is in a second plane, such that the first plane intersects the second plane. The device further includes a neck region joining the first expandable end region to the second expandable end region, wherein the neck region is sized and shaped for placement in the patient's atrial septum.

The present disclosure relates to a RF ablation catheter for septal reduction therapy having a cooling effect, and more particularly, to a RF ablation catheter for septal reduction therapy that is for performing RF ablation, in which RF energy is applied to an interventricular septum, for septal reduction therapy such as therapy for hypertrophic cardiomyopathy, which is a disease in which an interventricular septum of the left ventricle of the heart of the animal or human body thickens, therapy that requires reduction of an interventricular septum, or therapy for ventricular tachycardia. Also, the present disclosure relates to a RF ablation catheter for septal reduction therapy having a cooling effect that is for preventing carbonization of a tissue of the body (interventricular septum) around an electrode.An exemplary embodiment of the present disclosure provides a RF catheter for septal reduction therapy, the RF catheter including: an intra-septal part in which a tapered tip which becomes thinner toward an end thereof is formed at an end of a distal part and one or more electrodes are formed at positions on an outer circumferential surface that are adjacent to the tip; and a body part which is made of a soft material and has a guidewire lumen which passes through the intra-septal part from an inlet formed at the center of the end of the tip and has an outlet formed in a side surface, a coolant inlet lumen which is connected from a proximal part to an inner portion of the intra-septal part to allow a coolant to be injected from the outside and which has an open end, and a coolant outlet lumen which communicates with the coolant inlet lumen and has an exit formed in a side surface, wherein the guidewire lumen and the coolant inlet lumen do not communicate with each other and are partitioned from each other.

Interatrial shunts having incorporated physiologic sensors are provided for monitoring and treating cardiovascular syndromes, including heart failure and pulmonary hypertension, in which the one or more sensors are affixed to the shunt to measure a physiologic parameter within the interatrial shunt. The one or more sensors may be directly affixed to or within a lumenal surface of the shunt or may be disposed on a support structure in a spaced relation to the shunt lumen, the one or more sensors disposed at locations subject to little or no pannus formation or cardiac wall motion artifact.

Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.

An asymmetric device for regulating blood volume distribution across a patient's atrial septum having a first expandable end region and a second expandable end region. The first expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the first expandable end region extends into the patient's left atrium and an inlet end of the first expandable end region is in a first plane. The second expandable end region is transitionable from a contracted delivery state to an expanded deployed state in which the second expandable end region extends into the patient's right atrium and an outlet end of the second expandable end region is in a second plane, such that the first plane intersects the second plane. The device further includes a neck region joining the first expandable end region to the second expandable end region, wherein the neck region is sized and shaped for placement in the patient's atrial septum.

The present disclosure provides collapsible medical devices that may be introduced via a delivery device into a pre-existing patent foramen ovale or trans-septal puncture hole and left in place to provide both a sealing function on the atrial wall and a septal-access function for additional procedures. The disclosed medical devices include a penetrable and re-sealable gasket material disposed in an open lumen in the medical device. This penetrable and re-sealable material allows catheters or other medical devices to pass therethough for providing additional therapy to an individual. By allowing the access point or portal to be opened by a guidewire or another medical tool, the medical devices as disclosed herein may be particularly suitable for a variety of cardiac procedures including, for example, atrial fibrillation, mitral valve replacement or repair, left atrial appendage closures, and the like.

Devices and methods are described for facilitating passage of a probe or other element across an anatomical boundary. In some embodiments, the probe may be an intracardiac echo (ICE) probe, and the anatomical boundary may be the interatrial septum (IAS). The probe is delivered via transcatheter access from a femoral vein to the right atrium using a moveable guide catheter through which the probe and a wire with a resizable distal loop are advanced. The probe and wire may extend through respective lumens of the guide catheter. The loop may be resized to track, capture, and release a sheath, such that a transcatheter delivered medical device such as a left atrial appendage (LAA) occlusion device or other device, may traverse the IAS with the ICE probe via a single puncture site.

Interatrial shunts having incorporated physiologic sensors are provided for monitoring and treating cardiovascular syndromes, including heart failure and pulmonary hypertension, in which the one or more sensors are affixed to the shunt to measure a physiologic parameter within the interatrial shunt. The one or more sensors may be directly affixed to or within a lumenal surface of the shunt or may be disposed on a support structure in a spaced relation to the shunt lumen, the one or more sensors disposed at locations subject to little or no pannus formation or cardiac wall motion artifact.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

A method and system for performing transseptal extracorporeal membrane oxygenation is disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. A first portion of the catheter system can remove blood from the patient, in some examples near the inferior vena cava. A second portion can return oxygenated blood to the patient, through the transseptal puncture and into the aorta.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

This invention discloses a method for preparing a simulated heart model and the simulated heart model itself. The method for preparing the simulated heart model includes: dividing a digital heart model into two parts along its coronal plane; preparing corresponding molding molds according to the structural characteristics of the two parts, each molding mold including an outer molding mold and an inner cavity molding mold; applying silicone to the molding surfaces of the outer molding mold and the inner cavity molding mold to form the endocardium and epicardium; applying silicone to the portion of the inner cavity molding mold used for molding the valve to form the valve; assembling the outer molding mold and the inner cavity molding mold to form a cavity; sequentially injecting silicone of corresponding hardness into the regions of the cavity used for molding the atrial myocardium, interatrial septal myocardium, ventricular myocardium, and interventricular septal myocardium to form heart model halves; and bonding the heart model halves corresponding to the two molding molds together to obtain the simulated heart model.

The utility model belongs to the technical field of medical instruments, and particularly discloses a novel single-disc patent foramen ovale plugging device which structurally comprises a front disc, a rear support, a waist portion connecting the front disc and the rear support, a flow blocking film arranged in the front disc and wrapping the rear support, and a screw arranged on the outer side of the rear support. The front disc of the plugging device covers the left chamber outlet of the oval foramen after being unfolded, and shunting can be stopped as much as possible; the rear support in the right atrial septum is clamped on the right atrial septum after being unfolded, and the disc face of the left atrial septum is more tightly attached to the left atrial exit of the oval hole under the action of traction force of the rear support. Compared with a traditional foramen ovale plugging device, the foramen ovale plugging device can reduce shunting and thrombosis, and is better in applicability to long and narrow foramen ovale.

The present disclosure relates to medical devices. More particularly, this disclosure describes a vascular device allowing large bore transseptal access with subsequent atrial re-access by preplacing closures / tissue approximating sutures prior to creating a septostomy. Generally, the device may include a delivery catheter for puncturing and cutting the interatrial septum. An anchor of the delivery catheter may secure the suture in an atrium to a septum wall, for example, the left atrium. Incisions may be made by an expandable cutting implement which may use mechanical or radio frequency (RF) energy without interfering with the suture. A therapeutic instrument may be advanced through the tissue plane after the incisions are made by the cutting implement. Closure of the incision may be performed with the previously placed sutures.

The invention relates to an atrial septum puncture system which comprises a puncture needle body, an expansion tube and a handle part. The puncture needle body is movably arranged in the expansion tube, an exhaust gap is formed between the outer side of the needle wall of the puncture needle body and the inner side of the tube wall of the expansion tube, a first sealing structure is arranged between the puncture needle body and the expansion tube, and a through hole enabling the exhaust gap to be communicated with the needle cavity is formed in the needle wall. According to the interatrial septum puncture system, frequent exchange of a guide wire and a needle is not needed in the interatrial septum puncture operation process, operation steps are reduced, meanwhile, air can be exhausted, air can be prevented from entering the system in the use process, the probability that air enters the body of a patient can be reduced, and the operation efficiency is improved. And the risk of thrombus and thrombus formation of patients is reduced.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

This invention relates to a biodegradable cardiac occluder for bilateral rivetless atrial septal defects. The occluder includes a main body, a flow-blocking component, sutures, and a rivetless flat-face connector. The main body is a mesh structure comprising a first disc-shaped portion, a second disc-shaped portion, and a tubular portion. The flow-blocking component is a biodegradable membrane with at least two layers for blocking blood flow. The sutures are biodegradable sutures used to sew the flow-blocking component onto the main body and also serve as a closing suture. The rivetless flat-face connector includes a threaded hole and a delivery disc. This invention uses a small disc instead of rivets, achieving both re-delivery and the goal of reducing thrombosis incidence through rivetless design. The rivetless flat-face connector is biodegradable. During processing, it is woven into the mesh, making it convenient, safe, and quick.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

The present technology is generally directed to implantable medical devices and associated methods. For example, a system configured in accordance with embodiments of the present technology can include a body implantable into a patient and configured to undergo a shape change, the body having a conductive path with variable conductivity in portions thereof for selective and / or preferential heating. The body can be coupled with an energy source that can delivery energy to the body and / or conductive path, to promote the shape change in the body.

A method, system, and devices with an integrated retractable blade system for the intraarterial shunt are disclosed. According to one aspect, the cutting tool may comprise an elongate body where the elongate body has a proximal portion and a distal portion opposite the proximal portion. An inner shaft may extend within the distal portion of the elongate body and the inner shaft may have a proximal end and a distal end and a hub may be coupled to the distal end of the inner shaft. The cutting tool may have a cutting element with the hub coupled with the cutting element and movement of the hub transitions the cutting element between a collapsed position and an expanded position.

Anatomical wall crossing systems, devices, and related methods are disclosed in this patent document. An interatrial septum system may include, for example, a guidewire, a dilator, and a deflectable sheath, which is configured to safely deliver a puncture needle through an interatrial septum associated with the fossa ovalis and into a central region of the left atrium of the heart. The dilator may include a dilator nose having a first outer diameter and a dilator bevel section extending proximally from the dilator nose, which tapers from a second larger outer diameter to the first outer diameter. The lengths and interactions of the puncture needle and the dilator nose may be configured such that the puncture needle is inhibited from bending during use and striking the left side of the interatrial septum of the heart. The body of the guidewire may include at least one loop segment to provide stable support in the left atrium for delivering a diagnostic or therapeutic device along its more proximal portion. The deflectable sheath may position and align the dilator nose relative to the fossa ovalis.

The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and / or a geometry of a lumen orifice to control the flow of blood through the lumen.

The application provides a method for fixing an interventional valve on a mitral valve, which comprises the following steps: driving a plurality of fixing nails into the left atrial side wall above the mitral valve; and connecting a fixing disc on the atrial septum through a connecting line to form a plurality of fixing lines above the mitral valve. The fixing method can form a plurality of fixing lines above the mitral valve, and the fixing lines can provide stable fixing support for the interventional valve implanted below, thereby effectively solving the problem that the current interventional mitral valve is difficult to be stably anchored, and the method for fixing the interventional valve on the mitral valve is simple and convenient to operate.

The present invention provides an occluder, comprising a distal disc, a narrow middle portion, and a proximal disc which are formed in sequence. The proximal disc comprises a proximal disc surface. A proximal bending area is formed at a circumference of the proximal disc surface, and is bent towards the distal disc. The proximal bending area surrounds a circumference of the distal disc. A free end of the proximal bending area is further provided with a stabilizing wire passing through the free end. The stabilizing wire can tighten the free end of the proximal bending area towards the narrow middle portion. The occluder provided by the present invention features good stability, resistance to deformation, and close fit to the interatrial septum after implantation, thus facilitating endothelialization.

The present disclosure relates to medical devices. More particularly, this disclosure describes a vascular device allowing large bore transseptal access with subsequent atrial re-access by preplacing closures / tissue approximating sutures prior to creating a septostomy. Generally, the device may include a delivery catheter for puncturing and cutting the interatrial septum. An anchor of the delivery catheter may secure the suture in an atrium to a septum wall, for example, the left atrium. Incisions may be made by an expandable cutting implement which may use mechanical or radio frequency (RF) energy without interfering with the suture. A therapeutic instrument may be advanced through the tissue plane after the incisions are made by the cutting implement. Closure of the incision may be performed with the previously placed sutures.

An atrial shunt device, relating to the technical field of medical treatment. The atrial shunt device specifically comprises a first isolation membrane (4), the first isolation membrane (4) having a U-shaped structure in which the side surface is of a closed structure and the middle portion is recessed inwardly; and a second isolation membrane (5), the second isolation membrane (5) having a U-shaped structure in which the side surface thereof is of a closed structure and is arranged in the first isolation membrane (4), and the middle portion of the second isolation membrane (5) is recessed inwardly. The tops of the second isolation membrane (5) and the first isolation membrane (4) all have an arc-shaped structure, and two ends of the second isolation membrane (5) and the first isolation membrane (4) are all connected by means of arc-shaped connection portions (10), so as to form a sealed cavity between the second isolation membrane (5) and the first isolation membrane (4). The sealed cavity is internally provided with a support body for maintaining the shapes of the second isolation membrane (5) and the first isolation membrane (4). The atrial shunt device can block cells of the interatrial septum of a patient by means of the first isolation membrane (4) and the second isolation membrane (5), so as to avoid the reduction of the cross section of a shunt pathway due to proliferated cells at an interatrial septum orifice passing through first supporting strips (6) and second supporting strips (7), thereby improving the use effect.

A septostomy device 10 with a cutting structure or means 140 and tissue capture mechanisms 240, 250 is disclosed, along with a medical procedure for using the device. The system 10 is configured in such a way as to create a permanent interatrial aperture in the heart, including creating a permanent interatrial hole and / or removing tissue.

The utility model relates to the technical field of medical teaching tools, in particular to a pulmonary vein stenosis interventional operation training model, which comprises a bottom plate and a heart module mounted on the bottom plate, a left atrium and a right atrium are arranged in the heart module, and an inferior vena cava communicated with the right atrium is arranged on the heart module. The heart module is further provided with pulmonary veins communicated with the left atrium, through holes are formed in the left atrium and the right atrium at the interatrial septum position, sheet-shaped silica gel membranes are detachably installed at the positions of the through holes, and the heart module is provided with an operation opening in the upper side of the left atrium. The problems that when an existing training model carries out pulmonary vein stenosis interventional operation training, due to the fact that a stoma is a set through hole, when an operator is trained, the stoma puncturing step is omitted, and a good training effect on how to carry out interatrial septum puncturing is not achieved are solved.