A garment is disclosed that includes one or more selectively openable closure assemblies configured to provide controlled access to targeted anatomical regions of a wearer while maintaining overall garment coverage. The garment body, which may be a top, bottom, or unitary garment, incorporates at least one closure
assembly extending between two regions of the garment. Each closure
assembly comprises mateable closure elements, such as
interlocking zipper teeth, and at least a first slider and a second slider independently positionable to couple or uncouple the mateable elements. Movement of the sliders creates selectively openable access areas that
expose portions of the wearer's body, enabling medical procedures such as accessing implanted ports, vascular devices, infusion sites, or sensor modules. Independent slider positioning further defines a gap through which medical tubing, catheters, or cables may be routed without crimping. The garment enhances comfort, modesty, and functionality during
medical treatment or monitoring.